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Molecular Cell, ISSN 1097-2765, 07/2016, Volume 63, Issue 2, pp. 261 - 276
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 02/2013, Volume 587, Issue 4, pp. 311 - 316
► USP4 is overexpressed in head and neck squamous cell carcinoma. ► USP4 negatively regulates RIP1-mediated NF-κB activation. ► USP4 promotes TNF-α-induced... 
USP4 | Deubiquitination | RIP1 | Apoptosis | HNSCC | ubiquitin-specific protease 4 | receptor-interacting protein 1 | head and neck squamous cell carcinoma | SURVIVAL | KAPPA-B ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | DEATH | TRAF2 | CANCER | CELL BIOLOGY | BIOPHYSICS | PATHWAY | DEGRADATION | EXPRESSION | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Immunoprecipitation | Carcinoma, Squamous Cell - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Recombinant Fusion Proteins - metabolism | Head and Neck Neoplasms - metabolism | Recombinant Fusion Proteins - antagonists & inhibitors | Squamous Cell Carcinoma of Head and Neck | Ubiquitination | HEK293 Cells | Ubiquitin Thiolesterase - metabolism | Lysine - metabolism | Head and Neck Neoplasms - enzymology | Neoplasm Proteins - genetics | Ubiquitin Thiolesterase - antagonists & inhibitors | Ubiquitinated Proteins - metabolism | Recombinant Proteins - metabolism | Carcinoma, Squamous Cell - enzymology | Recombinant Proteins - antagonists & inhibitors | Down-Regulation | Gene Silencing | Ubiquitin Thiolesterase - genetics | Ubiquitin-Specific Proteases | Cell Line, Tumor | RNA, Small Interfering | Index Medicus
Journal Article
Science Signaling, ISSN 1945-0877, 01/2014, Volume 7, Issue 307, pp. ra3 - ra3
Ubiquitylation is an important mechanism for regulating innate immune responses to viral infections. Attachment of lysine 63 (Lys(63))-linked ubiquitin chains... 
INTERFERON INDUCTION | RESPONSES | PHOSPHORYLATION | NEGATIVE REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLYUBIQUITIN CHAINS | RNA VIRUSES | NF-KAPPA-B | ADAPTER PROTEIN | INNATE IMMUNITY | LIGASE | CELL BIOLOGY | Protein Binding - genetics | Ubiquitin-Specific Proteases - genetics | Interferon-beta - immunology | Antiviral Agents - immunology | Humans | Green Fluorescent Proteins - genetics | Antiviral Agents - metabolism | Tripartite Motif Proteins | Signal Transduction - immunology | Ubiquitin-Protein Ligases - immunology | Ubiquitination | RNA Interference | Proteolysis | HEK293 Cells | Lysine - metabolism | DEAD-box RNA Helicases - metabolism | Newcastle disease virus - immunology | Transcription Factors - immunology | Ubiquitin-Specific Proteases - metabolism | DEAD Box Protein 58 | Green Fluorescent Proteins - metabolism | Interferon-alpha - metabolism | Vesicular stomatitis Indiana virus - genetics | Sendai virus - immunology | Cells, Cultured | Ubiquitin-Protein Ligases - metabolism | Virus Replication - immunology | Signal Transduction - genetics | Transcription Factors - genetics | Protein Binding - immunology | Blotting, Western | Interferon-alpha - immunology | Transcription Factors - metabolism | DEAD-box RNA Helicases - genetics | Immunity, Innate - immunology | Microscopy, Confocal | Interferon-beta - metabolism | Newcastle disease virus - genetics | Ubiquitin-Specific Proteases - immunology | DEAD-box RNA Helicases - immunology | HeLa Cells | Proteasome Endopeptidase Complex - metabolism | Ubiquitin-Protein Ligases - genetics | Vesicular stomatitis Indiana virus - immunology | Index Medicus
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 03/2013, Volume 32, Issue 13, pp. 1660 - 1669
Journal Article