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Circulation research, ISSN 1524-4571, 2017, Volume 121, Issue 6, pp. 662 - 676
... (uncoupling protein 1)-dependent thermogenesis. Objective: We sought to determine the differential effects of ambient environmental temperature challenge and UCP1 activation in relation to cardiovascular disease progression... 
Bone marrow | Thermogenesis | Housing | Macrophages | Atherosclerosis | atherosclerosis | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | housing | BONE-MARROW | PROLIFERATION | BROWN ADIPOSE-TISSUE | HYPERCHOLESTEROLEMIA | bone marrow | macrophages | thermogenesis | INFLAMMATION | DISEASE | PERIPHERAL VASCULAR DISEASE | MICE | CHEMOKINE RECEPTORS | HEMATOLOGY | Receptors, CCR2 - genetics | Atherosclerosis - pathology | Cold Temperature | Uncoupling Protein 1 - genetics | Plaque, Atherosclerotic - metabolism | Atherosclerosis - physiopathology | Uncoupling Protein 1 - metabolism | Humans | Mice, Inbred C57BL | Monocytes - metabolism | Cholesterol - metabolism | Atherosclerosis - metabolism | Atherosclerosis - blood | Receptors, CCR2 - metabolism | Animals | Uncoupling Protein 1 - deficiency | Mice | Plaque, Atherosclerotic - blood | Monocytes - physiology | Cell Movement | CC chemokine receptors | Temperature | Animal models | Cardiovascular disease | Blood | Cholesterol | Glucose tolerance | Monocytes | Cell activation | CCR2 protein | Temperature effects | Uncoupling protein 1 | Arteriosclerosis | Adrenergic receptors | Cardiovascular diseases | Bone imaging | Localization | Monocyte chemoattractant protein 1 | Plaques | atherogenesis | Migration | Vascular Biology | adrenergic receptor | macrophage | Inflammation | Metabolism | Lipids and Cholesterol | Animal Models of Human Disease | positron emission tomography
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2012, Volume 441, Issue 2, pp. 523 - 540
...) proteins and 50 lysosomal hydrolases. Autophagosomes... 
Mitochondrion | Oxidative stress | Redox signalling | Neurodegeneration | Autophagy | Nitrative stress | autophagy | CHAPERONE-MEDIATED AUTOPHAGY | ANTIOXIDANT RESPONSIVE ELEMENTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIPOFUSCINOSES BATTEN-DISEASE | neurodegeneration | AMYOTROPHIC-LATERAL-SCLEROSIS | mitochondrion | redox signalling | MOTOR-NEURON DEGENERATION | MANGANESE SUPEROXIDE-DISMUTASE | nitrative stress | SMOOTH-MUSCLE-CELLS | PATHOGENIC DJ-1 MUTATIONS | HYPOXIA-INDUCED AUTOPHAGY | oxidative stress | COMPLEX-I DEFICIENCY | Protein Kinases - metabolism | Transcription, Genetic - drug effects | Cardiovascular Diseases - physiopathology | Reactive Oxygen Species - metabolism | Oxidation-Reduction | Reactive Nitrogen Species - metabolism | Humans | Oxidative Stress - physiology | Hydrogen Peroxide - pharmacology | Oncogene Proteins - metabolism | Nitric Oxide - physiology | Autophagy - physiology | Intracellular Signaling Peptides and Proteins - metabolism | Mitochondria - metabolism | Mitochondria - pathology | Parkinson Disease - physiopathology | Lysosomes - physiology | Protein Deglycase DJ-1 | Animals | Signal Transduction - physiology | TOR Serine-Threonine Kinases - physiology | Neoplasms - physiopathology | AMPK, 5′-AMP-activated protein kinase | NBR1, neighbour of BRCA1 (breast cancer early-onset 1) | NGF, nerve growth factor | LC3, light chain 3 | NOX, NADPH oxidase | EM, electron microscopy | TOR, target of rapamycin | ULK, unc (unco-ordinated family member)-51-like kinase | mtDNA, mitochondrial DNA | mTOR, mammalian target of rapamycin | IKKβ, IκB kinase β | LRRK2, leucine-rich repeat kinase 2 | NAC, N-acetyl-L-cysteine | Nrf2, nuclear factor-erythroid 2-related factor 2 | PI3P, phosphatidylinositol 3-phosphate | ECH, enoyl-CoA hydratase | BNIP3L, BNIP3-like | Drp1, dynamin-related protein 1 | tfLC3, tandem fluorescently tagged LC3 | NF-κB, nuclear factor κB | BAG, Bcl-2-associated athanogene | Keap1, Kelch-like ECH-associated protein 1 | PE, phosphatidylethanolamine | 3-MA, 3-methyladenine | UCP, uncoupling protein | IκB, inhibitor of nuclear factor κB | FIP200, focal adhesion kinase family-interacting protein of 200 kDa | PI3K, phosphoinositide 3-kinase | HNE, 4-hydroxynonenal | Review | ALS, amyotrophic lateral sclerosis | ATG, AuTophaGy-related | adenovirus E18 19-kDa-interacting protein | Tzb, trastuzumab | mETC, mitochondrial electron-transport chain | Rubicon, RUN domain- and cysteine-rich domain-containing beclin-1-interacting protein | VDAC, voltage-dependent anion channel | IP3, inositol 1,4,5-trisphosphate | RFP, red fluorescent protein | ROS, reactive oxygen species | TNFα, tumour necrosis factor α | PINK1, PTEN (phosphatase and tensin homologue deleted on chromosome 10)-induced kinase 1 | GFP, green fluorescent protein | LAMP, lysosome-associated membrane protein | JNK1, c-Jun N-terminal kinase 1 | TAC, transverse aortic constriction | GABARAP, GABAA (γ-aminobutyric acid type A)-receptor-associated protein | HIF-1, hypoxia-inducible factor 1 | NOS, nitric oxide synthase | siRNA, small interfering RNA | SOD, superoxide dismutase | RLS, reactive lipid species | RNS, reactive nitrogen species | ER, endoplasmic reticulum | TIGAR, TP53 (tumour protein 53)-induced glycolysis and apoptosis regulator | Vps34, vacuolar protein sorting 34 | BNIP, Bcl-2
Journal Article
Journal Article
Nature medicine, ISSN 1546-170X, 2012, Volume 18, Issue 10, pp. 1575 - 1579
Journal Article
Oncogene, ISSN 1476-5594, 2014, Volume 34, Issue 32, pp. 4229 - 4237
.... Here, we show that MnSOD deficiency in skin tissues of MnSOD-heterozygous knockout (Sod2(+/) (-)) mice leads to increased expresson of uncoupling proteins... 
OXIDATIVE STRESS | LIPID-PEROXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | CELL BIOLOGY | OVEREXPRESSION | SKIN CARCINOGENESIS MODEL | EPITHELIAL-CELLS | ONCOLOGY | GLUCOSE | GENETICS & HEREDITY | CANCER METABOLISM | PROTEIN-2 | EXPRESSION | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Ion Channels - genetics | Mitochondrial Proteins - genetics | Phosphatidylinositol 3-Kinases - metabolism | TOR Serine-Threonine Kinases - genetics | Mitochondria - genetics | RNA Interference | Mitochondrial Proteins - metabolism | Adenosine Triphosphate - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cells, Cultured | PPAR alpha - genetics | Superoxide Dismutase - deficiency | Mitochondria - metabolism | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Animals | Lactates - metabolism | Ion Channels - metabolism | Glycolysis | Uncoupling Protein 2 | PPAR alpha - metabolism | Uncoupling Protein 1 | Physiological aspects | Superoxide dismutase | Genetic aspects | Mitochondrial diseases | Research | Carcinogenesis | Risk factors | Antioxidants | Enzymes | Signal transduction | Protein expression | Mitochondria | Cancer | TOR protein | Reactive oxygen species | AKT protein | Superoxide | 1-Phosphatidylinositol 3-kinase | Tumorigenesis | Oxidation | Lactic acid | Manganese | Energetic metabolism | UCPs | Redox homeostasis | MnSOD | glycolysis
Journal Article
Nature (London), ISSN 1476-4687, 2016, Volume 532, Issue 7597, pp. 112 - 116
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 3/2017, Volume 114, Issue 10, pp. 2705 - 2710
Journal Article