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Neuroscience, ISSN 0306-4522, 2009, Volume 159, Issue 3, pp. 993 - 1002
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 1999
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2015, Volume 35, Issue 5, pp. 1166 - 1178
Objectives-Pulmonary hypertension (PH) is a process of lung vascular remodeling, which can lead to right heart dysfunction and significant morbidity. The... 
hypertension, pulmonary | endothelium | mitochondrial uncoupling protein 2 | autophagy | PTEN-induced putative kinase | mitochondrial degradation | APOPTOSIS | LUNG | MITOCHONDRIAL BIOGENESIS | CELL PROLIFERATION | MECHANISMS | MOUSE MODELS | DEFICIENCY | ARTERIAL | PERIPHERAL VASCULAR DISEASE | STRESS | HEMATOLOGY
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2014, Volume 35, Issue 2, pp. 421 - 430
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2015, Volume 125, Issue 2, pp. 665 - 680
Cellular lipid metabolism has been linked to immune responses; however, the precise mechanisms by which de novo fatty acid synthesis can regulate inflammatory... 
MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | GLUCOSE-METABOLISM | ATP-CITRATE LYASE | UCP2 | SEPTIC SHOCK | CELL-GROWTH | CRITICALLY-ILL PATIENTS | INTENSIVE INSULIN THERAPY | CANCER | MITOCHONDRIAL UNCOUPLING PROTEINS | Fatty Acid Synthase, Type I - genetics | Fatty Acid Synthase, Type I - biosynthesis | Lipids - genetics | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Ion Channels - genetics | Caspase 1 - metabolism | Mitochondrial Proteins - genetics | Interleukin-1beta - genetics | Lipids - biosynthesis | Sepsis - pathology | Interleukin-1beta - metabolism | Mitochondrial Proteins - metabolism | Sepsis - metabolism | Macrophages - pathology | Down-Regulation - genetics | Inflammasomes - genetics | Sepsis - genetics | Mice, Knockout | Carrier Proteins - genetics | Enzyme Induction - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Sepsis - chemically induced | Ion Channels - metabolism | Caspase 1 - genetics | Sepsis - therapy | Mice | Uncoupling Protein 2 | Interleukin-18 - genetics | Interleukin-18 - metabolism | Cellular proteins | Immune response | Synthesis | Sepsis | Development and progression | Lipids | Genetic aspects | Properties | Enzymes | Cytokines | Pathogenesis | Mortality | Glucose | Metabolism | Gene expression | Fatty acids | Proteins | Studies | Metabolites | Consent | Rodents
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e25436
Aims: Berberine, a botanical alkaloid purified from Coptidis rhizoma, is reported to activate the AMP-activated protein kinase (AMPK). Whether AMPK is required... 
SKELETAL-MUSCLE | OXYGEN SPECIES PRODUCTION | MITOCHONDRIAL BIOGENESIS | ENDOTHELIAL-CELLS | IN-VIVO | BIOLOGY | TRADITIONAL CHINESE MEDICINE | SMOOTH-MUSCLE-CELLS | HYDROGEN-PEROXIDE | GLUCOSE-UPTAKE | INSULIN SENSITIVITY | Transcription, Genetic - drug effects | AMP-Activated Protein Kinases - metabolism | Berberine - administration & dosage | Apolipoproteins E - deficiency | Cholesterol - blood | Humans | Ion Channels - genetics | Mitochondrial Proteins - genetics | Protein Transport - drug effects | Aorta - metabolism | Aldehydes - metabolism | Threonine - metabolism | Tyrosine - analogs & derivatives | Mitochondrial Proteins - metabolism | Phosphorylation - drug effects | Atherosclerosis - pathology | Atherosclerosis - drug therapy | Plaque, Atherosclerotic - metabolism | Aorta - drug effects | Mitochondrial Proteins - biosynthesis | Enzyme Activation - drug effects | Serine - metabolism | AMP-Activated Protein Kinases - chemistry | Atherosclerosis - metabolism | Aorta - pathology | Atherosclerosis - blood | Up-Regulation - drug effects | Berberine - pharmacology | Intercellular Adhesion Molecule-1 - metabolism | Tyrosine - metabolism | Animals | Ion Channels - metabolism | Triglycerides - blood | Mice | Uncoupling Protein 2 | Berberine - therapeutic use | Blood Glucose - metabolism | Vascular Cell Adhesion Molecule-1 - metabolism | Acetyl-CoA Carboxylase - metabolism | Acetyl-CoA Carboxylase - chemistry | Alkaloids | RNA | Atherosclerosis | Biosynthesis | Cardiovascular diseases | Protein kinases | Endothelium | Health sciences | Oxidative stress | Mitochondrial uncoupling protein 2 | Atherogenesis | Homeostasis | mRNA | Kinases | AMP-activated protein kinase | Cell adhesion & migration | Proteins | Mitochondria | Reduction | Hyperglycemia | Chinese medicine | Transfection | Apolipoprotein E | Rodents | Aorta | Physiology | Lesions | Heart diseases | Berberine | Immunoglobulins | AMP | siRNA | Metabolism | Gene expression | Endothelial cells | Studies | Diet | Arteriosclerosis | Nitric oxide | In vivo methods and tests | Diabetes | Umbilical vein | Veins & arteries
Journal Article