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Angewandte Chemie International Edition, ISSN 1433-7851, 01/2011, Volume 50, Issue 2, pp. 415 - 418
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Biochemistry, ISSN 0006-2960, 06/2011, Volume 50, Issue 24, pp. 5521 - 5534
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Journal of Controlled Release, ISSN 0168-3659, 06/2015, Volume 207, pp. 93 - 100
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Journal of Controlled Release, ISSN 0168-3659, 06/2017, Volume 255, pp. 54 - 61
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PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, pp. e0177877 - e0177877
Urate oxidase is a key enzyme in purine metabolism and catalyzes the oxidation of uric acid to allantoin. It is used to treat hyperuricemia and gout, and also... 
URICASE GENE | HYPERURICEMIA | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | PURIFICATION | RESOLUTION | RASBURICASE | ASPERGILLUS-FLAVUS | EXPRESSION | SP TB-90 | Directed Molecular Evolution - methods | Catalytic Domain | Temperature | Biocatalysis | Mutagenesis, Site-Directed | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Enzyme Stability | Models, Molecular | Bacillus subtilis - enzymology | Bacillus subtilis - genetics | Urate Oxidase - metabolism | Urate Oxidase - genetics | Epistasis, Genetic | Urate Oxidase - chemistry | Bacterial Proteins - metabolism | Protein Conformation | Kinetics | Amino Acid Substitution | Hyperuricemia | Gene mutations | Bacillus subtilis | Allopurinol | Dosage and administration | Research | Acute renal failure | Risk factors | High resolution | Error analysis | Allantoin | DNA polymerase | Gout | Series (mathematics) | Biochemistry | Fragmentation | Fungi | Degradation | Life sciences | Catalysis | Deoxyribonucleic acid--DNA | Enzymes | Construction | Stability | Upstream | Media | Gene expression | Metabolism | Chemicals | Amplification | Chemotherapy | Mutagenesis | Ampicillin | Lymphomas | Mutation | Structural analysis | Kidney transplantation | Biotechnology | Alkaline phosphatase | Cyanide | Media (culture) | Microbiology | Leukemia | Medical services | Oligonucleotides | Homology | Cyanides | Malignancy | Engineering | Arabinose | E coli | Biotransformation | Chemical bonds | Bacteria | Evolution | Rheumatism | Children | Biodegradation | Excretion | Kidneys | Purification | Hematology | Cloning | Crystallization | Uric acid | Lymphoma | Acids | Plasmids | Lysis | Amylosucrase | Combinatorial analysis | Index Medicus | Deoxyribonucleic acid | DNA
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