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Journal Article
Redox biology, ISSN 2213-2317, 04/2017, Volume 11, pp. 390 - 402
... the progression of fibrosis in rats that have undergone unilateral ureteral obstruction (UUO). Inhibiting Brd4 with either JQ1 or genetic knockdown resulted in decreased expression of fibrotic genes such as α... 
Nox4 | TGF-β1 | Renal fibrosis | Brd4 | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | RNA, Small Interfering - genetics | Ureteral Obstruction - complications | Reactive Oxygen Species - metabolism | Kidney - pathology | Humans | Male | Ureteral Obstruction - metabolism | Kidney - metabolism | Mitogen-Activated Protein Kinase 1 - genetics | Transforming Growth Factor beta1 - pharmacology | Kidney - drug effects | NADPH Oxidase 4 - genetics | Mitogen-Activated Protein Kinase 3 - genetics | Rats | Epithelial Cells - pathology | Rats, Sprague-Dawley | Reactive Oxygen Species - antagonists & inhibitors | Mitogen-Activated Protein Kinase 3 - metabolism | Fibrosis - etiology | Ureteral Obstruction - pathology | Collagen Type IV - genetics | Cell Cycle Proteins | Mitogen-Activated Protein Kinase 1 - metabolism | RNA, Small Interfering - metabolism | Epithelial Cells - metabolism | Transforming Growth Factor beta1 - antagonists & inhibitors | Epithelial Cells - drug effects | Actins - metabolism | Smad3 Protein - metabolism | Actins - genetics | Smad3 Protein - genetics | Fibrosis - prevention & control | Nuclear Proteins - genetics | Collagen Type IV - metabolism | Fibrosis - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Antioxidants - pharmacology | Transcription Factors - genetics | Fibronectins - metabolism | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | NADPH Oxidase 4 - metabolism | Animals | Nuclear Proteins - antagonists & inhibitors | Fibronectins - genetics | Fibrosis - pathology | Ureteral Obstruction - surgery | Cell Line, Transformed | Index Medicus
Journal Article
Medical science monitor, ISSN 1643-3750, 12/2019, Volume 25, pp. 9131 - 9137
Journal Article