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Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 35, pp. 37335 - 37348
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, pp. e27509 - e27509
Aberrant activation and mutation status of proteins in the phosphatidylinositol-3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) and the mitogen... 
MAMMALIAN TARGET | CELLS | LY294002 | PI3K | 3-KINASE | UROTHELIAL CARCINOMA | MULTIDISCIPLINARY SCIENCES | IN-VIVO | RAPAMYCIN INHIBITOR | PHOSPHATIDYLINOSITOL 3-KINASE/MAMMALIAN TARGET | MTOR | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Humans | Phosphatidylinositol 3-Kinases - metabolism | Phosphoproteins - metabolism | Quinolines - pharmacology | Dose-Response Relationship, Drug | Neoplasm Metastasis | Urinary Bladder Neoplasms - genetics | Time Factors | Urinary Bladder Neoplasms - pathology | Gene Expression Regulation, Neoplastic - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Everolimus | Urinary Bladder Neoplasms - metabolism | Carcinoma, Transitional Cell - genetics | Cell Survival - drug effects | Sirolimus - analogs & derivatives | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Carcinoma, Transitional Cell - metabolism | Imidazoles - pharmacology | Enzyme Activation - drug effects | Sirolimus - pharmacology | Carcinoma, Transitional Cell - pathology | Signal Transduction - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Adaptor Proteins, Signal Transducing - metabolism | Proteins | Chemical inhibitors | Growth | Protein kinases | TOR protein | Therapy | Phosphorylation | Crosstalk | Leukemia | Lung cancer | Bladder | AKT protein | Metastasis | Kinases | Cancer therapies | Urology | Signal transduction | Cell activation | Cell growth | Urinary bladder | Tumorigenesis | Inhibition | Urothelial carcinoma | MAP kinase | Rapamycin | siRNA | Bladder cancer | 1-Phosphatidylinositol 3-kinase | Signaling | Chemotherapy | Inhibitors | Protein kinase | Medical prognosis | Cell lines | Technology assessment | Mutation | Aberration | Tumors | Apoptosis | Cancer | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 11/2012, Volume 72, Issue 22, pp. 5843 - 5855
Fibroblast growth factor receptor 3 (FGFR3) belongs to a family of receptor tyrosine kinases that control cell proliferation, differentiation, and survival.... 
MULTIPLE-MYELOMA | LUNG-CANCER | FATTY-ACID SYNTHESIS | PROTEIN | ONCOLOGY | PHOSPHATIDYLINOSITOL 3-KINASE | GENE-EXPRESSION | FACTOR RECEPTOR-3 | CELL-GROWTH | CARCINOMA | ACTIVATING MUTATIONS | RNA, Small Interfering - genetics | TOR Serine-Threonine Kinases - metabolism | Humans | Urinary Bladder Neoplasms - enzymology | Cell Growth Processes - physiology | Transplantation, Heterologous | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Receptor, Fibroblast Growth Factor, Type 3 - metabolism | Gene Knockdown Techniques | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - metabolism | RNA, Messenger - biosynthesis | Urinary Bladder Neoplasms - genetics | Receptor, Fibroblast Growth Factor, Type 3 - deficiency | Urinary Bladder Neoplasms - pathology | Female | Fatty Acids - metabolism | Urinary Bladder Neoplasms - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Receptor, Fibroblast Growth Factor, Type 3 - genetics | Signal Transduction | RNA, Messenger - genetics | Stearoyl-CoA Desaturase - antagonists & inhibitors | Mice, SCID | Stearoyl-CoA Desaturase - genetics | Animals | Cell Cycle - physiology | Cell Line, Tumor | Stearoyl-CoA Desaturase - metabolism | Doxycycline - pharmacology | Mice | RNA, Small Interfering - administration & dosage | Fatty Acids - biosynthesis | Index Medicus
Journal Article
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 10/2017, Volume 43, Issue 1, pp. 405 - 418
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2005, Volume 115, Issue 4, pp. 978 - 985
The mainstay in the management of invasive bladder cancer continues to be radical cystectomy. With regard to improvement of quality of life, however, therapies... 
MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | SEVERE COMBINED IMMUNODEFICIENCY | POLO-LIKE-KINASE | INHIBITION | GENE-THERAPY | ADULT MICE | PROGNOSTIC-SIGNIFICANCE | CELL GROWTH | EXPRESSION | DELIVERY | Index Medicus | Abridged Index Medicus
Journal Article