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1. Full Text OnabotulinumtoxinA 100 U Significantly Improves All Idiopathic Overactive Bladder Symptoms and Quality of Life in Patients with Overactive Bladder and Urinary Incontinence: A Randomised, Double-Blind, Placebo-Controlled Trial
by Chapple, Christopher and Sievert, Karl-Dietrich and MacDiarmid, Scott and Khullar, Vik and Radziszewski, Piotr and Nardo, Christopher and Thompson, Catherine and Zhou, Jihao and Haag-Molkenteller, Cornelia
European Urology, ISSN 0302-2838, 2013, Volume 64, Issue 2, pp. 249 - 256
Abstract Background Overactive bladder (OAB) syndrome with urinary incontinence (UI) is prevalent in the population and impairs health-related quality of life... 
Urology | Urinary incontinence | OnabotulinumtoxinA | Overactive bladder | Botulinum toxin | POPULATION | EFFICACY | TRACT SYMPTOMS | BOTULINUM-TOXIN | DOSE-RANGING TRIAL | WOMEN | IMPACT | UROLOGY & NEPHROLOGY | QUESTIONNAIRE | ANTICHOLINERGIC THERAPY | United States | Humans | Middle Aged | Urodynamics - drug effects | Male | Neuromuscular Agents - therapeutic use | Botulinum Toxins, Type A - administration & dosage | Urinary Bladder - innervation | Botulinum Toxins, Type A - therapeutic use | Urinary Bladder, Overactive - drug therapy | Urinary Bladder, Overactive - psychology | Time Factors | Urinary Bladder, Overactive - physiopathology | Urination - drug effects | Neuromuscular Agents - administration & dosage | Adult | Female | Surveys and Questionnaires | Urinary Incontinence, Urge - drug therapy | Urinary Incontinence, Urge - physiopathology | Cholinergic Antagonists - therapeutic use | Botulinum Toxins, Type A - adverse effects | Urinary Bladder, Overactive - diagnosis | Double-Blind Method | Europe | Treatment Outcome | Urinary Incontinence, Urge - psychology | Injections, Intramuscular | Urinary Incontinence, Urge - diagnosis | Neuromuscular Agents - adverse effects | Quality of Life | Urinary Bladder - physiopathology | Urinary Bladder - drug effects | Aged | Clinical trials | Incontinence | Care and treatment
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2. Full Text Botulinum Toxin A (Botox® ) Intradetrusor Injections in Adults with Neurogenic Detrusor Overactivity/Neurogenic Overactive Bladder: A Systematic Literature Review
by Karsenty, Gilles and Denys, Pierre and Amarenco, Gérard and De Seze, Marianne and Gamé, Xavier and Haab, François and Kerdraon, Jacques and Perrouin-Verbe, Brigitte and Ruffion, Alain and Saussine, Christian and Soler, Jean-Marc and Schurch, Brigitte and Chartier-Kastler, Emmanuel
European Urology, ISSN 0302-2838, 2007, Volume 53, Issue 2, pp. 275 - 287
Abstract Objectives This systematic literature review discusses the efficacy and safety of botulinum toxin type A (Botox® ) intradetrusor injections in adults... 
Urology | Urinary incontinence | Urodynamics | Urinary bladder | Botulinum toxin type A | Overactive bladder | Neurogenic | Cholinergic antagonist | SPINAL-CORD LESIONS | cholinergic antagonist | MANAGEMENT | urinary bladder | MUSCLE | urodynamics | neurogenic | botulinum toxin type A | urinary incontinence | FORMULATIONS | UROLOGY & NEPHROLOGY | EXPERIENCE | AGENTS | overactive bladder | DIRECTIONS | URINARY-INCONTINENCE | Urinary Bladder, Neurogenic - physiopathology | Urinary Bladder, Overactive - drug therapy | Injections | Urinary Bladder, Overactive - physiopathology | Humans | Neuromuscular Agents - administration & dosage | Urodynamics - drug effects | Urinary Bladder, Neurogenic - drug therapy | Botulinum Toxins, Type A - administration & dosage | Botulinum toxin | Adults
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3. Full Text Combination Treatment with Mirabegron and Solifenacin in Patients with Overactive Bladder: Efficacy and Safety Results from a Randomised, Double-blind, Dose-ranging, Phase 2 Study (Symphony)
by Abrams, Paul and Kelleher, Con and Staskin, David and Rechberger, Tomasz and Kay, Richard and Martina, Reynaldo and Newgreen, Donald and Paireddy, Asha and van Maanen, Rob and Ridder, Arwin
European Urology, ISSN 0302-2838, 2014, Volume 67, Issue 3, pp. 577 - 588
Abstract Background Combining the β3-adrenoceptor agonist mirabegron and the antimuscarinic (AM) agent solifenacin may improve efficacy in the treatment of... 
Urology | Overactive bladder | Solifenacin | Combination therapy | Mirabegron | OUTLET OBSTRUCTION | TRIAL | THERAPY | URINARY-TRACT SYMPTOMS | MEN | UROLOGY & NEPHROLOGY | TAMSULOSIN | Humans | Middle Aged | Muscarinic Antagonists - adverse effects | Urodynamics - drug effects | Male | Muscarinic Antagonists - therapeutic use | Thiazoles - therapeutic use | Adrenergic beta-3 Receptor Agonists - adverse effects | Thiazoles - adverse effects | Urinary Bladder, Overactive - drug therapy | Urological Agents - adverse effects | Time Factors | Urinary Bladder, Overactive - physiopathology | Urination - drug effects | Acetanilides - therapeutic use | Adult | Female | Acetanilides - adverse effects | Urological Agents - therapeutic use | Urinary Bladder, Overactive - diagnosis | Double-Blind Method | Europe | Treatment Outcome | Solifenacin Succinate - therapeutic use | Adrenergic beta-3 Receptor Agonists - therapeutic use | Solifenacin Succinate - adverse effects | Urinary Bladder - physiopathology | Urinary Bladder - drug effects | Aged | Drug Combinations
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4. Full Text Population-Based Survey of Urinary Incontinence, Overactive Bladder, and Other Lower Urinary Tract Symptoms in Five Countries: Results of the EPIC Study
by Irwin, Debra E and Milsom, Ian and Hunskaar, Steinar and Reilly, Kate and Kopp, Zoe and Herschorn, Sender and Coyne, Karin and Kelleher, Con and Hampel, Christian and Artibani, Walter and Abrams, Paul and Giannantoni, Antonella and Institute of Clinical Sciences, Section for the Health of Women and Children and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institutionen för kliniska vetenskaper, sektionen för kvinnors och barns hälsa and Sahlgrenska Academy
European Urology, ISSN 0302-2838, 12/2006, Volume 50, Issue 6, pp. 1306 - 1315
Estimate the prevalence of urinary incontinence (UI), overactive bladder (OAB), and other lower urinary tract symptoms (LUTS) among men and women in five... 
Urinary incontinence | Epidemiologic survey | Prevalence | Adult | Overactive bladder | Lower urinary tract symptoms | Nocturia | DEFINITION | MODE | urinary incontinence | prevalence | CONTINENCE SOCIETY | WOMEN | SCORES | MEN | UROLOGY & NEPHROLOGY | nocturia | QUALITY-OF-LIFE | adult | lower urinary tract symptoms | epidemiologic survey | overactive bladder | Severity of Illness Index | Age Distribution | Urinary Incontinence - physiopathology | Cross-Sectional Studies | Humans | Middle Aged | Urinary Bladder, Overactive - epidemiology | Male | Sweden - epidemiology | Germany - epidemiology | Urodynamics - physiology | Canada - epidemiology | Urinary Bladder, Overactive - physiopathology | Adolescent | Sex Distribution | Female | Italy - epidemiology | Urinary Incontinence - epidemiology | Aged | Retrospective Studies | Population Surveillance | United Kingdom - epidemiology | MEDICIN OCH HÄLSOVETENSKAP | MEDICAL AND HEALTH SCIENCES
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5. Full Text Mirabegron in overactive bladder: A review of efficacy, safety, and tolerability
by Chapple, Christopher R and Cardozo, Linda and Nitti, Victor W and Siddiqui, Emad and Michel, Martin C
Neurourology and Urodynamics, ISSN 0733-2467, 01/2014, Volume 33, Issue 1, pp. 17 - 30
ABSTRACT Aims Mirabegron, the first β3‐adrenoceptor agonist to enter clinical practice, has a different mechanism of action from antimuscarinic agents. This... 
Mirabegron | overactive bladder | β3‐adrenoceptor agonist | adrenoceptor agonist | SELECTIVE BETA-ADRENOCEPTOR AGONIST | URINARY-BLADDER | MUSCARINIC RECEPTORS | PHASE-III | ANTIMUSCARINIC THERAPY | BETA-ADRENOCEPTORS | PATIENT PERCEPTION | DOUBLE-BLIND | UROLOGY & NEPHROLOGY | RITOBEGRON KUC-7483 | QUALITY-OF-LIFE | Urinary Bladder, Overactive - diagnosis | Humans | Urodynamics - drug effects | Treatment Outcome | Thiazoles - therapeutic use | Adrenergic beta-3 Receptor Agonists - adverse effects | Thiazoles - adverse effects | Urinary Bladder, Overactive - drug therapy | Urological Agents - adverse effects | Adrenergic beta-3 Receptor Agonists - therapeutic use | Animals | Urinary Bladder, Overactive - physiopathology | Acetanilides - therapeutic use | Urinary Bladder - physiopathology | Urinary Bladder - drug effects | Acetanilides - adverse effects | Urological Agents - therapeutic use | Drugs | Hypertension | Urinary incontinence | Urinary tract infections | Analysis | Clinical trials | Drug therapy
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6. Full Text Impact on Quality of Life of Urinary Incontinence and Overactive Bladder: A Systematic Literature Review
by Bartoli, Simona and Aguzzi, Giovanni and Tarricone, Rosanna
Urology, ISSN 0090-4295, 2010, Volume 75, Issue 3, pp. 491 - 500
The paper provides a systematization of the scientific evidence on quality of life of patients affected by urinary incontinence (UI) and overactive bladder... 
Urology | WOMEN SEEKING TREATMENT | RISK-FACTORS | MEN | UROLOGY & NEPHROLOGY | PATTERNS | PREVALENCE | STRESS | QUESTIONNAIRE | URGE | TRACT SYMPTOMS | UTILITY | Quality of Life | Urinary Incontinence - physiopathology | Urinary Bladder, Overactive - physiopathology | Humans
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7. Full Text The potential role of unregulated autonomous bladder micromotions in urinary storage and voiding dysfunction; overactive bladder and detrusor underactivity
by Drake, Marcus J and Kanai, Anthony and Bijos, Dominika A and Ikeda, Youko and Zabbarova, Irina and Vahabi, Bahareh and Fry, Christopher H
BJU International, ISSN 1464-4096, 01/2017, Volume 119, Issue 1, pp. 22 - 29
The isolated bladder shows autonomous micromotions, which increase with bladder distension, generate sensory nerve activity, and are altered in models of... 
detrusor underactivity | micromotions | urodynamics | LUTS | overactive bladder | detrusor overactivity | CORD-INJURED RATS | GUINEA-PIG BLADDER | MICRO-CONTRACTILE ACTIVITY | CONSCIOUS RATS | MICTURITION CYCLE | IN-VITRO | GAP-JUNCTIONS | TRACT FUNCTION | OUTFLOW OBSTRUCTION | UROLOGY & NEPHROLOGY | MODULATION | Urine | Urodynamics | Urinary Bladder, Overactive - physiopathology | Humans | Urinary Bladder - physiopathology | Urination Disorders - physiopathology | Urinary Bladder Diseases - physiopathology | Pressure | Urinary incontinence | Bladder | Overactive bladder
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8. Full Text Pelvic organ prolapse and overactive bladder
by Boer, T.A. de and Salvatore, S and Cardozo, L and Chapple, C and Kelleher, C and Kerrebroeck, P. van and Kirby, M.G and Koelbl, H and Espuna-Pons, M and Milsom, I and Tubaro, A and Wagg, A and Vierhout, M.E and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Section for the Health of Women and Children, Department of Obstetrics and Gynecology and Sahlgrenska Academy and Institutionen för kliniska vetenskaper, sektionen för kvinnors och barns hälsa, Avdelningen för obstetrik och gynekologi
Neurourology and Urodynamics, ISSN 0733-2467, 2010, Volume 29, Issue 1, pp. 30 - 39
AIMS: In this review we try to shed light on the following questions: *How frequently are symptoms of overactive bladder (OAB) and is detrusor overactivity... 
prevalence | detrusor overactivity | pathophysiology | surgical treatment | overactive bladder | pelvic organ prolapse | pessary | Overactive bladder | Prevalence; surgical treatment | Pelvic organ prolapse | Pathophysiology | Detrusor overactivity | Pessary | DETRUSOR MUSCLE | PARTIAL URETHRAL OBSTRUCTION | URODYNAMIC EVALUATION | RABBIT URINARY-BLADDER | ANTERIOR COLPORRHAPHY | MOTOR URGE INCONTINENCE | OUTFLOW OBSTRUCTION | UROLOGY & NEPHROLOGY | VAGINAL WALL PROLAPSE | QUALITY-OF-LIFE | STRESS-INCONTINENCE | Severity of Illness Index | Prevalence | Pelvic Organ Prolapse - physiopathology | Urinary Bladder Neck Obstruction - etiology | Urinary Bladder Neck Obstruction - physiopathology | Humans | Risk Factors | Urinary Bladder, Overactive - epidemiology | Pelvic Organ Prolapse - epidemiology | Pelvic Organ Prolapse - therapy | Treatment Outcome | Urinary Bladder, Overactive - therapy | Urinary Bladder, Overactive - etiology | Urinary Bladder Neck Obstruction - epidemiology | Pelvic Organ Prolapse - complications | Urinary Bladder, Overactive - physiopathology | Urogenital Surgical Procedures | Pelvic Floor - physiopathology | Urinary Bladder - physiopathology | Female | Urinary Bladder Neck Obstruction - therapy | Pessaries | complications | therapy | Urinary Bladder Neck Obstruction | MEDICIN OCH HÄLSOVETENSKAP | Pelvic Organ Prolapse | etiology | epidemiology | physiopathology | Pelvic Floor | Overactive | Urinary Bladder | MEDICAL AND HEALTH SCIENCES
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9. Full Text The impact of overactive bladder on mental health, work productivity and health‐related quality of life in the UK and Sweden: results from EpiLUTS
by Coyne, Karin S and Sexton, Chris C and Kopp, Zoe S and Ebel‐Bitoun, Caty and Milsom, Ian and Chapple, Chris and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Section for the Health of Women and Children, Department of Obstetrics and Gynecology and Sahlgrenska Academy and Institutionen för kliniska vetenskaper, sektionen för kvinnors och barns hälsa, Avdelningen för obstetrik och gynekologi
BJU International, ISSN 1464-4096, 11/2011, Volume 108, Issue 9, pp. 1459 - 1471
Study Type – Symptom prevalence (prospective cohort) Level of Evidence 1b OBJECTIVE • To examine the prevalence and burden of overactive bladder (OAB) with... 
OAB | anxiety | bother | work productivity | health‐related quality of life | depression | burden | health-related quality of life | CONDITION PPBC | DEPRESSION SCALE | HOSPITAL ANXIETY | CULTURAL-ADAPTATION | PATIENT PERCEPTION | CARE-SEEKING BEHAVIOR | URINARY-TRACT SYMPTOMS | UROLOGY & NEPHROLOGY | QUESTIONNAIRE | EPIDEMIOLOGY | Depression - epidemiology | Prevalence | Cross-Sectional Studies | Lower Urinary Tract Symptoms - psychology | Humans | Middle Aged | Urinary Bladder, Overactive - epidemiology | Male | Lower Urinary Tract Symptoms - epidemiology | Sweden - epidemiology | Urinary Bladder, Overactive - psychology | Urinary Bladder, Overactive - physiopathology | Efficiency | Anxiety - epidemiology | Quality of Life | Female | Surveys and Questionnaires | Internet | Health Status | United Kingdom - epidemiology | Depression, Mental | Analysis | Mental health | Obstetrics, Gynecology and Reproductive Medicine | Reproduktionsmedicin och gynekologi
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10. Full Text Flexible-dose fesoterodine in elderly adults with overactive bladder: results of the randomized, double-blind, placebo-controlled study of fesoterodine in an aging population trial
by Wagg, Aian and Khullar, Vik and Marschall-Kehrel, Daniela and Michel, Martin C and Oelke, Matthias and Darekar, Amanda and Bitoun, Caty E and Weinstein, David and Osterloh, Ian
Journal of the American Geriatrics Society, ISSN 0002-8614, 2013, Volume 61, Issue 2, pp. 185 - 193
To assess the efficacy and safety of flexible-dose fesoterodine in elderly adults with overactive bladder (OAB). Twelve-week, randomized, double-blind,... 
fesoterodine | overactive bladder | flexible dosing | antimuscarinic | elderly | TOLTERODINE EXTENDED-RELEASE | EFFICACY | VALIDATION | GERIATRICS & GERONTOLOGY | CONTINENCE SOCIETY | OLDER POPULATION | URINARY-TRACT SYMPTOMS | TOLERABILITY | URGE INCONTINENCE | GERONTOLOGY | QUALITY-OF-LIFE | HEAD-TO-HEAD | Benzhydryl Compounds - administration & dosage | Double-Blind Method | Drug Administration Schedule | Follow-Up Studies | Humans | Male | Treatment Outcome | Dose-Response Relationship, Drug | Urinary Bladder, Overactive - drug therapy | Urinary Bladder, Overactive - physiopathology | Urination - drug effects | Aging | Female | Surveys and Questionnaires | Aged | Retrospective Studies | Clinical trials | Bladder | Drug therapy | Medical disorders | Older people | Urology
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