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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2006, Volume 103, Issue 38, pp. 14170 - 14175
Journal Article
PLoS Pathogens, ISSN 1553-7366, 09/2018, Volume 14, Issue 9, p. e1007102
Manganese (Mn) is an essential micronutrient that is not readily available to pathogens during infection due to an active host defense mechanism known as... 
URINARY-TRACT-INFECTIONS | ENTERICA SEROVAR TYPHIMURIUM | MICROBIOLOGY | GENETIC-CHARACTERIZATION | MURINE MODEL | STREPTOCOCCUS-PNEUMONIAE | VIROLOGY | FULL VIRULENCE | STAPHYLOCOCCUS-AUREUS | ENDOCARDITIS | SUPEROXIDE-DISMUTASE | PARASITOLOGY | BIOFILM FORMATION | Moths - microbiology | Catheter-Related Infections - etiology | Endocarditis, Bacterial - etiology | Catheter-Related Infections - metabolism | Humans | Leukocyte L1 Antigen Complex - metabolism | Biofilms - growth & development | Gram-Positive Bacterial Infections - metabolism | Urinary Tract Infections - metabolism | ATP-Binding Cassette Transporters - genetics | Cation Transport Proteins - metabolism | Moths - metabolism | Gram-Positive Bacterial Infections - microbiology | ATP-Binding Cassette Transporters - metabolism | Endocarditis, Bacterial - microbiology | Cation Transport Proteins - genetics | Urinary Tract Infections - microbiology | Disease Models, Animal | Rabbits | Enterococcus faecalis - pathogenicity | Endocarditis, Bacterial - metabolism | Enterococcus faecalis - genetics | Bacterial Proteins - genetics | Gram-Positive Bacterial Infections - etiology | Animals | Enterococcus faecalis - metabolism | Manganese - metabolism | Catheter-Related Infections - microbiology | Urinary Tract Infections - etiology | Virulence - physiology | Bacterial Proteins - metabolism | Mice | Physiological aspects | Research | Virulence (Microbiology) | Binding proteins | Endocarditis | Salmonella | Pathogenesis | Funding | Virulence | Disseminated infection | Gram-positive bacteria | Homeostasis | Infections | Urinary tract | Inactivation | Immunity | Proteins | Permease | Chelation | Urinary tract infections | Bacteria | Nosocomial infections | Nramp protein | Urogenital system | Supervision | Urine | Medical research | Bacterial infections | Deactivation | Computational fluid dynamics | Redundancy | Medical instruments | Antimicrobial agents | Bioavailability | Dentistry | Metabolism | Zinc | Urinary tract diseases | Medicine | Body fluids | Infectious diseases | Antibiotics | Womens health | Oral hygiene | Nutrient availability | Invertebrates | Manganese
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2016, Volume 22, Issue 11, pp. 1277 - 1284
Bacterial infection is highly prevalent in patients who have had a stroke. Despite the potential contribution of micro-aspiration in post-stroke pneumonia, we... 
MEDICINE, RESEARCH & EXPERIMENTAL | VENTILATOR-ASSOCIATED PNEUMONIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROBIOTA | CELL BIOLOGY | STROKE | ASPIRATION PNEUMONIA | TRAUMATIC BRAIN-INJURY | RESISTANCE | CENTRAL-NERVOUS-SYSTEM | STAPHYLOCOCCUS-AUREUS | COMPLICATIONS | DYSFUNCTION | Enterococcus faecalis | Bacteremia - immunology | Gram-Positive Bacterial Infections - immunology | Humans | Middle Aged | Male | Infarction, Middle Cerebral Artery - immunology | Pneumonia, Bacterial - metabolism | Gram-Positive Bacterial Infections - metabolism | Bacteremia - microbiology | Adrenergic beta-Antagonists - pharmacology | Urinary Tract Infections - metabolism | Bacterial Infections - immunology | Gram-Positive Bacterial Infections - microbiology | Aged, 80 and over | Female | Urinary Tract Infections - microbiology | Zonula Occludens-1 Protein - metabolism | Receptors, Adrenergic, beta - metabolism | Bacterial Infections - microbiology | Stroke - immunology | Disease Models, Animal | Permeability - drug effects | Pneumonia, Bacterial - microbiology | Specific Pathogen-Free Organisms | Blood Culture | Intestine, Small - microbiology | Computational Biology | Bacterial Translocation - immunology | Gastrointestinal Microbiome - genetics | Goblet Cells - metabolism | Bacteremia - metabolism | Animals | Sequence Analysis, RNA | Intestine, Small - cytology | Microbiota - genetics | Intestine, Small - drug effects | RNA, Ribosomal, 16S - genetics | Pneumonia, Bacterial - immunology | Aged | High-Throughput Nucleotide Sequencing | Mice | Intestine, Small - metabolism | Urinary Tract Infections - immunology | Bacterial Infections - metabolism | Goblet Cells - cytology | Stroke (Disease) | Ribosomal RNA | Bacteria, Pathogenic | Physiological aspects | Genetic aspects | Virulence (Microbiology) | Identification and classification | Stroke | Pneumonia | Bacterial infections
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2015, Volume 11, Issue 1, pp. 1 - 13
Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 09/2016, Volume 90, Issue 3, pp. 568 - 579
Journal Article
Kidney International, ISSN 0085-2538, 06/2018, Volume 93, Issue 6, pp. 1320 - 1329
The signaling networks regulating antimicrobial activity during urinary tract infection (UTI) are incompletely understood. Interleukin-6 (IL-6) levels increase... 
Stat3 | antimicrobial peptide | urothelium | intracellular bacterial community | IL-6 | urinary tract infection | UROPATHOGENIC ESCHERICHIA-COLI | CELLS | INNATE IMMUNE-RESPONSE | EPITHELIAL CYTOKINE RESPONSES | ACUTE PYELONEPHRITIS | RECEPTOR KNOCKOUT MICE | UROLOGY & NEPHROLOGY | HEPCIDIN EXPRESSION | BACTERIAL-INFECTION | BLADDER | Hepcidins - metabolism | Phosphorylation | Urothelium - metabolism | Cystitis - metabolism | Humans | Cystitis - genetics | Escherichia coli Infections - genetics | Urinary Tract Infections - metabolism | Escherichia coli - pathogenicity | STAT3 Transcription Factor - deficiency | Female | Urinary Tract Infections - microbiology | Urinary Bladder - microbiology | Urothelium - microbiology | Interleukin-6 - metabolism | Pancreatitis-Associated Proteins - genetics | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Disease Models, Animal | Cell Line | Urinary Tract Infections - genetics | Signal Transduction | Urinary Bladder - metabolism | Mice, Inbred C57BL | Cystitis - microbiology | Escherichia coli Infections - microbiology | Escherichia coli Infections - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Inbred C3H | Mice, Knockout | Host-Pathogen Interactions | Animals | Hepcidins - genetics | Pancreatitis-Associated Proteins - metabolism | Animal models | Antimicrobial activity | Bladder | Urinary tract | Kinases | Urology | Interleukin 6 | Proteins | Inoculation | Clonal deletion | E coli | Transcription activation | Toll-like receptors | Bacteria | Urinary tract infections | Urogenital system | Cystitis | Enzymes | Phenotypes | Cytokines | Secretion | Stat3 protein | Antimicrobial agents | Roles | TLR4 protein | Gene expression | Pyelonephritis | Protein expression | Urothelium
Journal Article