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Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 01/2011, Volume 66, Issue 1, pp. 1 - 14
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PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0167522
In this study, we retrospectively reviewed the clinical experience of patients receiving doripenem-containing regimens for the treatment of... 
IN-VITRO | MULTICENTER | BACTERIAL-INFECTIONS | IMIPENEM-CILASTATIN | EFFICACY | VENTILATOR-ASSOCIATED PNEUMONIA | SAFETY | PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | SURVEILLANCE | ANTIMICROBIAL ACTIVITY | Soft Tissue Infections - mortality | Urinary Tract Infections - mortality | Humans | Middle Aged | Cross Infection - mortality | Male | Tertiary Care Centers - statistics & numerical data | Hospital Mortality - trends | Respiratory Tract Infections - microbiology | Anti-Bacterial Agents - therapeutic use | Cross Infection - pathology | Respiratory Tract Infections - mortality | Soft Tissue Infections - pathology | Aged, 80 and over | Female | Urinary Tract Infections - microbiology | Urinary Tract Infections - pathology | Retrospective Studies | Soft Tissue Infections - drug therapy | Respiratory Tract Infections - pathology | Intraabdominal Infections - microbiology | Respiratory Tract Infections - drug therapy | Treatment Outcome | Cross Infection - drug therapy | Urinary Tract Infections - drug therapy | Intraabdominal Infections - mortality | Intraabdominal Infections - pathology | Soft Tissue Infections - microbiology | Carbapenems - therapeutic use | Cross Infection - microbiology | Aged | Intraabdominal Infections - drug therapy | APACHE | Infection | Doripenem | Care and treatment | Dosage and administration | Health care | Therapy | Pneumonia | Intensive care | Medical services | Medical records | Infections | Urinary tract | Drug resistance | Respiratory tract | Respiratory tract diseases | Urinary tract infections | Urogenital system | Pathogens | Ventilators | Medical research | Statistical analysis | Bacterial infections | Review boards | Mortality | Antimicrobial agents | Patients | Abdomen | Urinary tract diseases | Medicine | Studies | Hospitals | Antibiotics | Pharmacy | Skin | Adults
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 02/2015, Volume 112, Issue 8, pp. E871 - E880
Urinary tract infections (UTIs) are among the most common bacterial infections, causing considerable morbidity in females. Infection is highly recurrent... 
Urinary tract infection | Microbial pathogenesis | Uropathogenic E. coli | Persistent colonization | persistent colonization | CASPASE-1 | INFLAMMASOME ACTIVATION | MULTIDISCIPLINARY SCIENCES | microbial pathogenesis | NLRP3 INFLAMMASOME | VIRULENCE | uropathogenic E. coli | PATHOGENESIS | HOST DEFENSES | GRAM-NEGATIVE BACTERIA | EPITHELIAL-CELLS | BLADDER INFECTION | STRESS | urinary tract infection | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Hemolysin Proteins - genetics | Humans | Apoptosis - genetics | Caspase 1 - metabolism | Colony Count, Microbial | Urinary Bladder - pathology | Escherichia coli Infections - genetics | Virulence - genetics | Uropathogenic Escherichia coli - pathogenicity | Female | Urinary Tract Infections - microbiology | Urinary Tract Infections - pathology | Urinary Bladder - microbiology | Uropathogenic Escherichia coli - physiology | Interleukin-1beta - secretion | Acute Disease | Urinary Tract Infections - genetics | Urinary Bladder - metabolism | Escherichia coli Infections - microbiology | Escherichia coli Proteins - metabolism | Signal Transduction - genetics | Uropathogenic Escherichia coli - genetics | Disease Progression | Animals | Carrier Proteins - metabolism | Escherichia coli Infections - pathology | Models, Biological | Escherichia coli Proteins - genetics | Bacterial Proteins - metabolism | Mice | Enzyme Activation | Gene Expression Regulation, Bacterial | Chronic Disease | Hemolysin Proteins - metabolism | Biological Sciences | PNAS Plus
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PLoS Pathogens, ISSN 1553-7366, 08/2010, Volume 6, Issue 8, pp. 29 - 30
Journal Article
Nature Medicine, ISSN 1078-8956, 06/2006, Volume 12, Issue 6, pp. 636 - 641
The urinary tract functions in close proximity to the outside environment, yet must remain free of microbial colonization to avoid disease. The mechanisms for... 
MEDICINE, RESEARCH & EXPERIMENTAL | UROPATHOGENIC ESCHERICHIA-COLI | LL-37 | HCAP-18 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEFENSE PEPTIDES | BETA-DEFENSIN-1 | CELL BIOLOGY | MICE | BLADDER | DIFFERENTIATION | EXPRESSION | INNATE IMMUNITY | Urothelium - cytology | Epithelial Cells - metabolism | Urothelium - metabolism | Kidney Cortex - metabolism | Anti-Infective Agents - pharmacology | Escherichia coli - drug effects | Humans | Immunity, Mucosal | Drug Resistance, Bacterial | Antimicrobial Cationic Peptides - metabolism | Microbial Sensitivity Tests | Urinary Tract Infections - microbiology | Urinary Tract Infections - pathology | Urothelium - microbiology | Antimicrobial Cationic Peptides - genetics | Epithelial Cells - cytology | Child | Neutrophils - metabolism | Urinary Tract - microbiology | Antimicrobial Cationic Peptides - urine | Kidney Cortex - cytology | Mice, Inbred C57BL | Antimicrobial Cationic Peptides - pharmacology | Escherichia coli Infections - microbiology | Kidney Cortex - pathology | Mice, Knockout | Kidney Cortex - microbiology | Animals | Escherichia coli Infections - pathology | Epithelial Cells - microbiology | Escherichia coli Infections - immunology | Mice | Urinary Tract - drug effects | Urinary Tract Infections - immunology | Bacteria | Bacterial infections | Peptides | Urogenital system
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