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Neuropsychopharmacology, ISSN 0893-133X, 05/2010, Volume 35, Issue 6, pp. 1241 - 1252
Recent evidence suggests that corticotropin-releasing factor (CRF) receptor (CRFR) signaling is involved in modulating binge-like ethanol consumption in... 
Binge drinking | C57BL/6J mice | HPA axis | Ethanol consumption | CRF receptor | Drinking in the dark | IN-THE-DARK | CENTRAL NUCLEUS | PSYCHIATRY | ethanol consumption | RECEPTOR MESSENGER-RNA | binge drinking | ALCOHOL-CONSUMPTION | ANXIETY-LIKE BEHAVIOR | NEUROSCIENCES | NEUROPEPTIDE-Y | RESTRAINT STRESS | CORTICOTROPIN-RELEASING-FACTOR | drinking in the dark | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | PITUITARY-ADRENAL AXIS | Receptors, Corticotropin-Releasing Hormone - metabolism | Injections, Intraventricular | Receptors, Corticotropin-Releasing Hormone - agonists | Male | Peptide Fragments - pharmacology | Hypothalamo-Hypophyseal System - secretion | Alcohol-Induced Disorders, Nervous System - metabolism | Corticotropin-Releasing Hormone - therapeutic use | Urocortins - pharmacology | Pyrroles - therapeutic use | Disease Models, Animal | Hypothalamo-Hypophyseal System - drug effects | Urocortins - therapeutic use | Mice, Inbred C57BL | Injections, Intraperitoneal | Pyrimidines - pharmacology | Hypothalamo-Hypophyseal System - metabolism | Corticotropin-Releasing Hormone - pharmacology | Hormone Antagonists - pharmacology | Alcohol-Induced Disorders, Nervous System - drug therapy | Pyrroles - pharmacology | Animals | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Signal Transduction - drug effects | Pyrimidines - therapeutic use | Alcohol-Induced Disorders, Nervous System - physiopathology | Signal Transduction - physiology | Hormone Antagonists - therapeutic use | Mice | Peptide Fragments - therapeutic use | Pyridines - pharmacology | Mifepristone - pharmacology | Index Medicus | Addiction & Substance Abuse | C57BL | Psychopharmacology | 6J mice | Alcohol & Alcoholism | Neuropeptides | Original
Journal Article
Neuropharmacology, ISSN 0028-3908, 2003, Volume 45, Issue 5, pp. 623 - 636
Corticotropin-releasing factor (CRF) receptors are members of the superfamily of G-protein coupled receptors that utilise adenylate cyclase and subsequent... 
β-Amyloid | Neuroprotection | Central nervous system neurons | Phosphatidylinositol 3-kinase | Glycogen synthase kinase-3 | Apoptosis | CEREBELLAR GRANULE NEURONS | ALZHEIMERS-DISEASE | GLYCOGEN-SYNTHASE KINASE-3 | apoptosis | POTASSIUM DEPOLARIZATION | NEUROSCIENCES | HORMONE-MEDIATED NEUROPROTECTION | CELL-DEATH | beta-amyloid | CYCLIC-AMP | glycogen synthase kinase-3 | neuroprotection | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | GROWTH-FACTOR | central nervous system neurons | phosphatidylinositol 3-kinase | Cerebellum | Urocortins | Chromatin - metabolism | Receptors, Corticotropin-Releasing Hormone - metabolism | Urotensins - pharmacology | Protein-Serine-Threonine Kinases | Mitogen-Activated Protein Kinase Kinases - metabolism | Drug Interactions | Neuroprotective Agents - pharmacology | Cyclic AMP - analogs & derivatives | Time Factors | Corticotropin-Releasing Hormone - antagonists & inhibitors | Cerebral Cortex - drug effects | Phosphorylation - drug effects | Chromones - pharmacology | Cyclic AMP - metabolism | Animals, Newborn | Cell Survival - drug effects | Blotting, Western - methods | Amphibian Proteins | Colforsin - pharmacology | Enzyme Inhibitors - pharmacology | Rats | In Situ Nick-End Labeling - methods | Pyrimidines - pharmacology | Thionucleotides - pharmacology | Rats, Sprague-Dawley | 1-Methyl-3-isobutylxanthine - pharmacology | Corticotropin-Releasing Hormone - pharmacology | Cerebral Cortex - physiology | Enzyme-Linked Immunosorbent Assay - methods | L-Lactate Dehydrogenase - metabolism | Amyloid beta-Peptides - pharmacology | Peptide Fragments - pharmacology | Hippocampus - drug effects | Dose-Response Relationship, Drug | Peptide Hormones | Inhibitory Concentration 50 | Neurons - drug effects | Proto-Oncogene Proteins - metabolism | Vasodilator Agents - pharmacology | Cells, Cultured | Morpholines - pharmacology | Glycogen Synthase Kinase 3 - metabolism | Peptides - pharmacology | Cyclic AMP - pharmacology | Proto-Oncogene Proteins c-akt | Pyrroles - pharmacology | Animals | Hippocampus - physiology | Index Medicus
Journal Article
Psychoneuroendocrinology, ISSN 0306-4530, 2015, Volume 64, pp. 66 - 78
Highlights • Male prairie voles show high passive stress-coping after loss of female partner. • This is mediated via activation of CRFR2 in nucleus accumbens... 
Endocrinology & Metabolism | Psychiatry | Corticotropin-releasing factor | Passive stress-coping | Social loss | Stresscopin | Partner separation | Grieving | DEPRESSION | PSYCHIATRY | BEHAVIOR | MECHANISMS | SOCIAL ATTACHMENT | NEUROSCIENCES | BED NUCLEUS | ANTIDEPRESSANTS | CORTICOTROPIN-RELEASING-FACTOR | ENDOCRINOLOGY & METABOLISM | VASOPRESSIN | SYSTEMS | HYPOTHALAMUS | Paraventricular Hypothalamic Nucleus - physiology | Oxytocin - pharmacology | Receptors, Corticotropin-Releasing Hormone - metabolism | Urocortins - administration & dosage | Pair Bond | Male | Peptide Fragments - pharmacology | Peptides, Cyclic - pharmacology | Nucleus Accumbens - physiology | Peptides, Cyclic - administration & dosage | Radioimmunoassay | Neurons - physiology | Female | Corticotropin-Releasing Hormone - administration & dosage | Urocortins - pharmacology | Luminescent Proteins | Membrane Potentials - drug effects | Microinjections | Receptors, Oxytocin - antagonists & inhibitors | Peptide Fragments - administration & dosage | RNA, Small Interfering - pharmacology | Oxytocin - physiology | Vasotocin - pharmacology | Arvicolinae - physiology | Membrane Potentials - physiology | Vasotocin - analogs & derivatives | Bacterial Proteins | Corticotropin-Releasing Hormone - pharmacology | Autoradiography | Oxytocin - administration & dosage | Receptors, Corticotropin-Releasing Hormone - physiology | Receptors, Oxytocin - metabolism | Animals | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Corpus Striatum - physiology | Death | Vasotocin - administration & dosage | Infusions, Intraventricular | Nucleus Accumbens - drug effects | RNA, Small Interfering - administration & dosage | Adaptation, Psychological | Stress management | Neuropeptides | Stress (Psychology) | Neurophysiology | Corticotropin releasing hormone | Health aspects | Monogamy | Index Medicus | corticotropin-releasing factor | grieving | stresscopin | passive stress-coping | social loss | partner separation
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2008, Volume 28, Issue 2, pp. 407 - 414
Journal Article
Journal Article
Neuropharmacology, ISSN 0028-3908, 2006, Volume 51, Issue 5, pp. 1013 - 1022
Neuropeptide Y (NPY) and corticotropin-releasing factor (CRF) have opposing effects on stress and anxiety. Both can modify synaptic activity through their... 
Neuropeptide Y | Electrophysiology | Anxiety | Whole cell | CRF | Extended amygdala | COCAINE SEEKING | PROTEIN-KINASE | neuropeptide Y | KNOCKOUT MICE | DIFFERENTIAL REGULATION | NEUROSCIENCES | HYPOTHALAMIC PARAVENTRICULAR NUCLEUS | VENTRAL TEGMENTAL AREA | anxiety | MESSENGER-RNAS | electrophysiology | whole cell | STRESS-INDUCED REINSTATEMENT | FACTOR CRF | PHARMACOLOGY & PHARMACY | extended amygdala | Y-2 RECEPTORS | Urocortins | gamma-Aminobutyric Acid - metabolism | Male | Neurons - cytology | Peptide Fragments - pharmacology | Pyridazines - pharmacology | Septal Nuclei - cytology | Excitatory Postsynaptic Potentials - drug effects | Receptors, Corticotropin-Releasing Hormone - deficiency | Patch-Clamp Techniques - methods | Drug Interactions | Synaptic Transmission - drug effects | Neurons - drug effects | Electric Stimulation - methods | Aniline Compounds - pharmacology | Mice, Inbred C57BL | Neuropeptide Y - pharmacology | Pyrimidines - pharmacology | Corticotropin-Releasing Hormone - pharmacology | GABA Antagonists - pharmacology | Mice, Knockout | Animals | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Analysis of Variance | Mice | In Vitro Techniques | Dose-Response Relationship, Radiation | Inhibitory Postsynaptic Potentials - drug effects | Corticotropin releasing hormone | GABA | Index Medicus
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 10/2007, Volume 293, Issue 4, pp. G903 - G910
Journal Article
Canadian Journal of Cardiology, ISSN 0828-282X, 2014, Volume 30, Issue 6, pp. 687 - 695
Abstract Background Urocortin-1 (UCN1) exerts protective effects on hypoxia/reoxygenation injury in the heart. Serum- and glucocorticoid- responsive kinase-1... 
Cardiovascular | HEART | APOPTOSIS | ISCHEMIA/REPERFUSION INJURY | IN-VITRO | CARDIAC & CARDIOVASCULAR SYSTEMS | PEPTIDES | AKT ACTIVATION | SIGNALING PATHWAY | GENE-EXPRESSION | SERUM | KINASE SGK | Phosphorylation | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Peptide Fragments - pharmacology | Peptides, Cyclic - pharmacology | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | RNA, Messenger - metabolism | Gene Knockdown Techniques | Hypoxia - metabolism | Isoquinolines - pharmacology | Hypoxia - prevention & control | Models, Animal | Flavonoids - pharmacology | Urocortins - pharmacology | Chromones - pharmacology | Real-Time Polymerase Chain Reaction | Animals, Newborn | Immediate-Early Proteins - physiology | Protein-Serine-Threonine Kinases - physiology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Morpholines - pharmacology | Rats | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Reverse Transcriptase Polymerase Chain Reaction | Sulfonamides - pharmacology | Blotting, Western | Animals | Immediate-Early Proteins - genetics | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Reperfusion Injury - prevention & control | Myocytes, Cardiac - physiology | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2008, Volume 578, Issue 2, pp. 242 - 248
We planned to determine the primary effects and mechanisms of urocortin II, a member of the corticotrophin-releasing factor (CRF) family highly expressed in... 
Corticotrophin releasing factor | Coronary blood flow | Urocortin II | Nitric oxide | Myocardial contractility | nitric oxide | RAT | HEART-FAILURE | CRF2 RECEPTORS | RELAXATION | FAMILY | MEMBER | ENDOTHELIUM | urocortin II | PHARMACOLOGY & PHARMACY | coronary blood flow | myocardial contractility | ISCHEMIA-REPERFUSION | corticotrophin releasing factor | K+ CHANNELS | MURINE HEART | Anesthesia, General | Receptors, Corticotropin-Releasing Hormone - metabolism | Urocortins - administration & dosage | Cardiac Output | Nitric Oxide Synthase - antagonists & inhibitors | Peptide Fragments - pharmacology | Adrenergic alpha-Antagonists - pharmacology | Vasodilation | Coronary Vessels - metabolism | Adrenergic beta-Antagonists - pharmacology | Urocortins - metabolism | Propranolol - pharmacology | Muscarinic Antagonists - pharmacology | Myocardium - metabolism | Heart - innervation | Myocardial Contraction | NG-Nitroarginine Methyl Ester - pharmacology | Coronary Vessels - drug effects | Coronary Vessels - enzymology | Autonomic Nervous System - drug effects | Ventricular Function, Left - drug effects | Enzyme Inhibitors - pharmacology | Atropine - pharmacology | Phentolamine - pharmacology | Regional Blood Flow | Myocardium - enzymology | Animals | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Heart - drug effects | Nitric Oxide Synthase - metabolism | Ventricular Pressure | Coronary Circulation - drug effects | Nitric Oxide - metabolism | Sus scrofa | Infusions, Intra-Arterial | Swine | Index Medicus
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 01/2013, Volume 18, Issue 1, pp. 86 - 92
Dendritic spines are important sites of excitatory neurotransmission in the brain with their function determined by their structure and molecular content.... 
stress | dendritic development | maturation | spine | synapse | cerebellum | PSYCHIATRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRENATAL STRESS | NEUROSCIENCES | PREFRONTAL CORTEX | DENDRITIC SPINES | HIPPOCAMPUS | ACTIN CYTOSKELETON | DIFFERENTIATION | RECEPTORS | BRAIN | PLASTICITY | Peptide Hormones - pharmacology | Fluorescent Dyes - metabolism | Peptide Fragments - pharmacology | rhoA GTP-Binding Protein - metabolism | Peptide Hormones - metabolism | Purkinje Cells - cytology | Time Factors | Dendritic Spines - drug effects | Stress, Psychological - metabolism | Egtazic Acid - analogs & derivatives | Corticotropin-Releasing Hormone - antagonists & inhibitors | Post-Synaptic Density - drug effects | Post-Synaptic Density - metabolism | Tetrodotoxin - pharmacology | Organ Culture Techniques | Animals, Newborn | Membrane Potentials - drug effects | Microscopy, Electron, Transmission | Synapses - drug effects | Aniline Compounds - pharmacology | Vesicular Glutamate Transport Protein 1 - metabolism | Rats | Sodium Channel Blockers - pharmacology | Synapses - ultrastructure | Post-Synaptic Density - ultrastructure | Chelating Agents - pharmacology | Pyrimidines - pharmacology | Membrane Potentials - physiology | Corticotropin-Releasing Hormone - metabolism | Corticotropin-Releasing Hormone - pharmacology | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Stress, Psychological - pathology | Microscopy, Confocal | Patch-Clamp Techniques | Animals | Egtazic Acid - pharmacology | Dendritic Spines - pathology | Cerebellum - cytology | Purkinje Cells - pathology | Dendritic Spines - ultrastructure | Corticotropin releasing hormone | Care and treatment | Spine | Growth | Physiological aspects | Dendrites | Stress (Psychology) | Health aspects | Synapses | Cerebellum | postsynaptic density | Brain | Cell culture | Mental disorders | Synaptogenesis | urocortin | RhoA protein | Corticotropin-releasing hormone | Stress | Dendritic spines | Signal transduction | Purkinje cells | Synaptic transmission | Plasticity (developmental) | Neurotransmission | Index Medicus
Journal Article