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Pharmacological reviews, ISSN 0031-6997, 2015, Volume 67, Issue 1, pp. 214 - 258
Journal Article
Neuropharmacology, ISSN 0028-3908, 2003, Volume 45, Issue 5, pp. 623 - 636
Corticotropin-releasing factor (CRF) receptors are members of the superfamily of G-protein coupled receptors that utilise adenylate cyclase and subsequent... 
β-Amyloid | Neuroprotection | Central nervous system neurons | Phosphatidylinositol 3-kinase | Glycogen synthase kinase-3 | Apoptosis | CEREBELLAR GRANULE NEURONS | ALZHEIMERS-DISEASE | GLYCOGEN-SYNTHASE KINASE-3 | apoptosis | POTASSIUM DEPOLARIZATION | NEUROSCIENCES | HORMONE-MEDIATED NEUROPROTECTION | CELL-DEATH | beta-amyloid | CYCLIC-AMP | glycogen synthase kinase-3 | neuroprotection | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | GROWTH-FACTOR | central nervous system neurons | phosphatidylinositol 3-kinase | Cerebellum | Urocortins | Chromatin - metabolism | Receptors, Corticotropin-Releasing Hormone - metabolism | Urotensins - pharmacology | Protein-Serine-Threonine Kinases | Mitogen-Activated Protein Kinase Kinases - metabolism | Drug Interactions | Neuroprotective Agents - pharmacology | Cyclic AMP - analogs & derivatives | Time Factors | Corticotropin-Releasing Hormone - antagonists & inhibitors | Cerebral Cortex - drug effects | Phosphorylation - drug effects | Chromones - pharmacology | Cyclic AMP - metabolism | Animals, Newborn | Cell Survival - drug effects | Blotting, Western - methods | Amphibian Proteins | Colforsin - pharmacology | Enzyme Inhibitors - pharmacology | Rats | In Situ Nick-End Labeling - methods | Pyrimidines - pharmacology | Thionucleotides - pharmacology | Rats, Sprague-Dawley | 1-Methyl-3-isobutylxanthine - pharmacology | Corticotropin-Releasing Hormone - pharmacology | Cerebral Cortex - physiology | Enzyme-Linked Immunosorbent Assay - methods | L-Lactate Dehydrogenase - metabolism | Amyloid beta-Peptides - pharmacology | Peptide Fragments - pharmacology | Hippocampus - drug effects | Dose-Response Relationship, Drug | Peptide Hormones | Inhibitory Concentration 50 | Neurons - drug effects | Proto-Oncogene Proteins - metabolism | Vasodilator Agents - pharmacology | Cells, Cultured | Morpholines - pharmacology | Glycogen Synthase Kinase 3 - metabolism | Peptides - pharmacology | Cyclic AMP - pharmacology | Proto-Oncogene Proteins c-akt | Pyrroles - pharmacology | Animals | Hippocampus - physiology
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 06/2001, Volume 88, Issue 11, pp. 1102 - 1104
The aim of this work was to investigate the coupling of human urotensin II (hU-II) to RhoA activation and regulation of RhoA-dependent functions. The use of... 
Signal transduction | Vascular | G protein | SIGNAL-TRANSDUCTION | CARDIAC & CARDIOVASCULAR SYSTEMS | SENSITIZATION | PROTEIN-KINASE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | VASOCONSTRICTION | Norepinephrine - antagonists & inhibitors | Norepinephrine - pharmacology | Muscle, Smooth, Vascular - metabolism | Rats, Wistar | Recombinant Fusion Proteins - pharmacology | Urotensins - pharmacology | Humans | rhoA GTP-Binding Protein - metabolism | Recombinant Fusion Proteins - metabolism | Botulinum Toxins | Dose-Response Relationship, Drug | Vasoconstriction - physiology | Urotensins - metabolism | Potassium Chloride - pharmacology | rho-Associated Kinases | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | ADP Ribose Transferases - metabolism | Muscle, Smooth, Vascular - drug effects | Amides - pharmacology | Vasoconstrictor Agents - pharmacology | Vasoconstrictor Agents - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Aorta, Thoracic - metabolism | Intracellular Signaling Peptides and Proteins | Rats | rhoA GTP-Binding Protein - antagonists & inhibitors | Muscle, Smooth, Vascular - cytology | Vasoconstriction - drug effects | Cell Division - drug effects | ADP Ribose Transferases - genetics | Aorta, Thoracic - cytology | Animals | Signal Transduction - drug effects | ADP Ribose Transferases - pharmacology | Cytoskeleton - metabolism | Recombinant Fusion Proteins - genetics | Signal Transduction - physiology | Pyridines - pharmacology | In Vitro Techniques | Enzyme Activation - physiology | Cytoskeleton - drug effects
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2002, Volume 438, Issue 3, pp. 159 - 170
Human urotensin II-(1-11) and its N-terminally shortened analogues, human urotensin II-(4-11)-OH and human urotensin II-(4-11)-NH are potent vasoconstrictor... 
Tyrosine kinase | Protein kinase C | rat | Rho-kinase | Aorta contraction | Urotensin II | Somatostatin-receptor antagonist | Somatostatin | human | Phospholipase C | Human | Rat | aorta contraction, rat | phospholipase C | CELLS | somatostatin-receptor antagonist | SMALL ARTERIES | GPR14 | RAT | tyrosine kinase | VASCULAR SMOOTH-MUSCLE | urotensin II, human | CYTOSOLIC-FREE CALCIUM | CLONING | somatostatin | VASOCONSTRICTOR | PHARMACOLOGY & PHARMACY | LIGAND | protein kinase C | AGONIST | Protein Kinases - metabolism | Urotensins - pharmacology | Protein-Tyrosine Kinases - metabolism | Humans | Male | Peptide Fragments - pharmacology | Peptides, Cyclic - pharmacology | Phenanthridines - pharmacology | Urotensins - chemistry | Dose-Response Relationship, Drug | Alkaloids | Piperidines - pharmacology | Protein Kinase C - metabolism | Aorta, Thoracic - physiology | Estrenes - pharmacology | Pyrrolidinones - pharmacology | rho-Associated Kinases | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Receptors, Somatostatin - antagonists & inhibitors | Aorta, Thoracic - drug effects | Protein-Serine-Threonine Kinases - metabolism | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | Rats | Protein Kinase C - antagonists & inhibitors | Tyrphostins - pharmacology | Calcium Channel Blockers - pharmacology | Rats, Sprague-Dawley | Vasoconstriction - drug effects | Aorta, Thoracic - enzymology | Protein Kinase Inhibitors | Animals | Benzophenanthridines | Genistein - pharmacology | In Vitro Techniques | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2004, Volume 143, Issue 3, pp. 422 - 430
A biphasic cardiovascular response to bolus i.v. injection of human urotensin II (hUII, 3 nmol kg −1 ) in conscious, male, Sprague–Dawley (SD) rats was... 
cyclooxygenase | nitric oxide | Urotensin II | spontaneously hypertensive rats | haemodynamics | Haemodynamics | Spontaneously hypertensive rats | Cyclooxygenase | Nitric oxide | VASODILATOR RESPONSES | ACETYLCHOLINE | NITRIC-OXIDE SYNTHASE | HUMAN UROTENSIN-II | INVOLVEMENT | CENTRAL CARDIOVASCULAR ACTION | urotensin II | ARGININE METHYL-ESTER | POTENT | IN-VIVO | PHARMACOLOGY & PHARMACY | HEART-RATE | Injections, Intravenous | Urotensins - pharmacology | Humans | Rats, Inbred F344 | Rats, Inbred Lew | Nitric Oxide Synthase - antagonists & inhibitors | Rats, Inbred WKY | Male | Arginine - analogs & derivatives | Heart Rate - drug effects | Cardiovascular System - physiopathology | Propranolol - pharmacology | Cardiovascular Physiological Phenomena - drug effects | Blood Pressure - drug effects | NG-Nitroarginine Methyl Ester - pharmacology | Rats, Inbred SHR | Vasoconstrictor Agents - pharmacology | Vasodilator Agents - pharmacology | Consciousness | Enzyme Inhibitors - pharmacology | Losartan - pharmacology | Rats | Cardiovascular System - drug effects | Urotensins - administration & dosage | Arginine Vasopressin - pharmacology | Rats, Sprague-Dawley | Vasoconstriction - drug effects | Indomethacin - pharmacology | Animals | Arginine - pharmacology | Amidines - pharmacology | Hemodynamics - drug effects | Vasodilation - drug effects | Benzylamines - pharmacology | Indans - pharmacology | Papers
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 07/2004, Volume 142, Issue 6, pp. 921 - 932
In an effort to identify endogenous, native mammalian urotensin‐II (U‐II) receptors (UT), a diverse range of human, primate and rodent cell lines (49 in total)... 
Urotensin‐II | GPR14 | skeletal muscle | rhabdomyosarcoma | G‐protein‐coupled receptor | Urotensin-II | Skeletal muscle | G-protein-coupled receptor | Rhabdomyosarcoma | ENDOGENOUS LIGAND | RAT SPINAL-CORD | RHO-KINASE | RELEASE | SMOOTH-MUSCLE | CONTRACTION | ORPHAN-RECEPTOR | SOMATOSTATIN | VASOCONSTRICTOR | NEUROPEPTIDE | PHARMACOLOGY & PHARMACY | urotensin-II | Immunohistochemistry | Iodine Radioisotopes | Receptors, G-Protein-Coupled - metabolism | Urotensins - pharmacology | Calcium - metabolism | Humans | Rhabdomyosarcoma - metabolism | Rhabdomyosarcoma - pathology | Male | Gene Expression Profiling | Dose-Response Relationship, Drug | Urotensins - metabolism | Female | Pituitary Hormones - pharmacology | Radioligand Assay | Binding Sites | Pertussis Toxin - pharmacology | Cell Line | Neurophysins - pharmacology | Intracellular Space - drug effects | Calcitonin Gene-Related Peptide - pharmacology | Urotensins - genetics | Vasopressins - pharmacology | Neuropeptide Y - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Hypothalamic Hormones - pharmacology | Melanins - pharmacology | Binding, Competitive - drug effects | Protein Precursors - pharmacology | Blotting, Northern | Animals | Intracellular Space - metabolism | Cell Line, Tumor | Thapsigargin - pharmacology | HeLa Cells | Kinetics | Papers
Journal Article
Hypertension Research, ISSN 0916-9636, 10/2006, Volume 29, Issue 10, pp. 821 - 831
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2007, Volume 150, Issue 4, pp. 415 - 423
Journal Article