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Journal of Medical Genetics, ISSN 0022-2593, 12/2011, Volume 48, Issue 12, pp. 856 - 859
ObjectiveTo investigate the potential contribution of germline sequence alterations in the BAP1 gene in uveal melanoma (UM) patients with possible... 
BREAST-CANCER | GENE | HIGH-RISK | GENETICS & HEREDITY | TUMOR-SUPPRESSOR | BRCA1 | UBIQUITIN HYDROLASE | BRCA1-ASSOCIATED PROTEIN-1 | Adenocarcinoma - pathology | Genetic Testing | Adenocarcinoma of Lung | Humans | Lung Neoplasms - metabolism | Middle Aged | Gene Expression Regulation, Neoplastic | Genetic Diseases, Inborn - genetics | Lung Neoplasms - pathology | Male | Meningioma - genetics | Genetic Diseases, Inborn - pathology | Loss of Heterozygosity | Adenocarcinoma - metabolism | DNA Mutational Analysis | Melanoma - genetics | Tumor Suppressor Proteins - genetics | Germ-Line Mutation | Ubiquitin Thiolesterase - metabolism | Adult | Female | Adenocarcinoma - genetics | Genetic Diseases, Inborn - metabolism | Uveal Neoplasms - metabolism | Microsatellite Repeats | Lung Neoplasms - genetics | Melanoma - metabolism | Uveal Neoplasms - genetics | Genetic Predisposition to Disease - genetics | Tumor Suppressor Proteins - metabolism | Meningeal Neoplasms - genetics | Meningioma - metabolism | Uveal Neoplasms - pathology | Gene Silencing | Chromosomes, Human, Pair 3 - metabolism | Melanoma - pathology | Ubiquitin Thiolesterase - genetics | Meningioma - pathology | Pedigree | Meningeal Neoplasms - metabolism | Meningeal Neoplasms - pathology | Chromosomes, Human, Pair 3 - genetics | Genetic aspects | Research | BRCA mutations | Cancer
Journal Article
Pathology, ISSN 0031-3025, 02/2013, Volume 45, Issue 2, pp. 116 - 126
BAP1 (BRCA1-Associated Protein 1) was initially identified as a protein that binds to BRCA1. BAP1 is a tumour suppressor that is believed to mediate its... 
pathology | familial cancer | uveal melanoma | skin | diagnosis | inherited tumour susceptibility | melanoma | 3p21 loss syndrome | atypical Spitz tumour | germline mutation | BAP1 | Pathology | Inherited tumour susceptibility | Melanoma | Uveal melanoma | Atypical Spitz tumour | Familial cancer | Germline mutation | Skin | Diagnosis | PLEURAL MESOTHELIOMA | DNA-DAMAGE RESPONSE | BRCA1-ASSOCIATED PROTEIN-1 | RENAL-CELL CARCINOMA | BREAST-CANCER | POLYCOMB GROUP PROTEINS | SPITZ NEVI | HISTONE DEACETYLASE INHIBITORS | MALIGNANT MESOTHELIOMA | MYELODYSPLASTIC SYNDROMES | Neoplasms - metabolism | Carcinoma, Neuroendocrine - diagnosis | Melanoma - diagnosis | Humans | Lung Neoplasms - metabolism | Meningioma - genetics | Neoplasms - diagnosis | Paraganglioma - diagnosis | Adenocarcinoma - metabolism | Neoplasms - genetics | DNA Mutational Analysis | Melanoma - genetics | Gene Deletion | Nevus, Epithelioid and Spindle Cell - genetics | Skin Neoplasms - diagnosis | Tumor Suppressor Proteins - genetics | Biomarkers, Tumor - metabolism | Adenocarcinoma - genetics | Uveal Neoplasms - metabolism | Carcinoma, Neuroendocrine - metabolism | Lung Neoplasms - genetics | Melanoma - metabolism | Uveal Neoplasms - genetics | Genetic Predisposition to Disease | Meningioma - metabolism | Paraganglioma - genetics | Carcinoma, Neuroendocrine - genetics | Mesothelioma - diagnosis | Mesothelioma - genetics | Nevus, Epithelioid and Spindle Cell - metabolism | Ubiquitin Thiolesterase - genetics | Skin Neoplasms - metabolism | Immunohistochemistry - methods | Nevus, Epithelioid and Spindle Cell - diagnosis | Adenocarcinoma - diagnosis | Mesothelioma - metabolism | Paraganglioma - metabolism | Skin Neoplasms - genetics | Uveal Neoplasms - diagnosis | Biomarkers, Tumor - genetics | Meningioma - diagnosis | Mutation | Lung Neoplasms - diagnosis
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2014, Volume 25, Issue 6, pp. 831 - 845
Journal Article
PLoS Biology, ISSN 1544-9173, 09/2011, Volume 9, Issue 9, p. e1001162
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2014, Volume 25, Issue 6, pp. 822 - 830
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 06/2012, Volume 36, Issue 6, pp. 818 - 830
Journal Article
Cell, ISSN 0092-8674, 11/2015, Volume 163, Issue 4, pp. 811 - 828
Journal Article