X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1603) 1603
humans (1477) 1477
mutation (977) 977
proto-oncogene proteins b-raf - genetics (931) 931
cancer (822) 822
female (772) 772
male (764) 764
oncology (759) 759
braf (753) 753
braf mutation (683) 683
braf v600e mutation (675) 675
middle aged (648) 648
adult (560) 560
melanoma (514) 514
aged (473) 473
thyroid neoplasms - genetics (467) 467
pathology (446) 446
carcinoma (431) 431
prognosis (411) 411
thyroid cancer (404) 404
genetic aspects (393) 393
thyroid neoplasms - pathology (379) 379
tumors (375) 375
gene mutations (359) 359
braf v600e (326) 326
vemurafenib (322) 322
v600e mutation (319) 319
endocrinology & metabolism (309) 309
immunohistochemistry (295) 295
diagnosis (274) 274
metastasis (249) 249
thyroid cancer, papillary (244) 244
expression (236) 236
v600e (236) 236
surgery (230) 230
metastatic melanoma (228) 228
analysis (227) 227
papillary thyroid carcinoma (226) 226
association (222) 222
aged, 80 and over (219) 219
young adult (217) 217
melanoma - genetics (214) 214
proto-oncogene proteins b-raf - metabolism (211) 211
cell biology (206) 206
research (206) 206
neoplasms (203) 203
adolescent (202) 202
dna mutational analysis (201) 201
animals (197) 197
survival (194) 194
carcinoma, papillary (192) 192
biomarkers, tumor - genetics (184) 184
thyroid (181) 181
carcinoma - genetics (180) 180
care and treatment (177) 177
carcinoma, papillary - genetics (173) 173
health aspects (173) 173
article (172) 172
b-raf (169) 169
retrospective studies (169) 169
proto-oncogene proteins b-raf - antagonists & inhibitors (166) 166
abridged index medicus (165) 165
endocrine system diseases (162) 162
kinases (160) 160
cell line, tumor (156) 156
mutations (153) 153
mutation - genetics (152) 152
colorectal cancer (151) 151
thyroid neoplasms - diagnosis (150) 150
medicine & public health (144) 144
nodules (142) 142
gene (139) 139
neoplasm staging (138) 138
melanoma - pathology (137) 137
melanoma - drug therapy (133) 133
papillary thyroid cancer (133) 133
carcinoma - pathology (131) 131
activation (130) 130
microsatellite instability (129) 129
thyroid neoplasms - metabolism (128) 128
recurrence (127) 127
carcinoma, papillary - pathology (126) 126
antineoplastic agents - therapeutic use (124) 124
management (121) 121
patients (120) 120
digestive system diseases (119) 119
colorectal neoplasms - genetics (118) 118
child (116) 116
development and progression (116) 116
pathway (116) 116
high prevalence (115) 115
treatment outcome (115) 115
risk factors (114) 114
cells (113) 113
medicine, research & experimental (112) 112
fine-needle-aspiration (111) 111
dabrafenib (108) 108
polymerase chain reaction (107) 107
resistance (106) 106
thyroid neoplasms - surgery (106) 106
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2263) 2263
French (16) 16
German (13) 13
Korean (5) 5
Spanish (5) 5
Russian (2) 2
Chinese (1) 1
Hungarian (1) 1
Japanese (1) 1
Polish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, 1/2016, Volume 142, Issue 1, pp. 89 - 100
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 7/2011, Volume 122, Issue 1, pp. 11 - 19
Journal Article
CLINICAL ENDOCRINOLOGY, ISSN 0300-0664, 06/2014, Volume 80, Issue 6, pp. 899 - 904
Journal Article
Nature, ISSN 0028-0836, 09/2010, Volume 467, Issue 7315, pp. 596 - 599
B-RAF is the most frequently mutated protein kinase in human cancers. The finding that oncogenic mutations in BRAF are common in melanoma, followed by the... 
ACTIVATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | MUTATION | KERATOACANTHOMAS | SENSITIVITY | SENESCENCE | SORAFENIB | HUMAN CANCER | PROGRESSION | BRAF(V600E) | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Macaca fascicularis | Melanoma - enzymology | Substrate Specificity | Positron-Emission Tomography | Extracellular Signal-Regulated MAP Kinases - metabolism | Indoles - administration & dosage | Neoplasm Metastasis | Melanoma - genetics | Phosphorylation - drug effects | Mutant Proteins - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Sulfonamides - chemistry | Mutant Proteins - genetics | Models, Molecular | Rats | Mutant Proteins - metabolism | Melanoma - pathology | Mutation - genetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Indoles - adverse effects | MAP Kinase Signaling System - drug effects | Sulfonamides - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Mutant Proteins - chemistry | Alleles | Dogs | Sulfonamides - adverse effects | Indoles - therapeutic use | Indoles - chemistry | Sulfonamides - administration & dosage | Control | Gene mutations | Melanoma | Development and progression | Genetic aspects | Research | Health aspects | Protein kinases | Cancer | Proteins | Mutation | Kinases | Rodents | Index Medicus | targeted therapy | melanoma | BRAF | PLX4032 | biomarker | oncogene
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 09/2014, Volume 38, Issue 9, pp. 1235 - 1241
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 2011, Volume 121, Issue 3, pp. 397 - 405
Missense mutations of the V600E type constitute the vast majority of tumor-associated somatic alterations in the v-RAF murine sarcoma viral oncogene homolog B1... 
Brain tumor | Pathology | Neurosciences | Ganglioglioma | V600E mutation | Medicine & Public Health | BRAF | Pleomorphic xanthoastrocytoma | GLIOMAS | B-RAF GENE | PATHOLOGY | CANCER | NEUROSCIENCES | CLINICAL NEUROLOGY | PATHWAY ACTIVATION | ATYPICAL TERATOID/RHABDOID TUMOR | COMPONENT | DUPLICATION | INHIBITOR | MAPK PATHWAY | EXPRESSION | Astrocytoma - genetics | Gene Frequency - genetics | World Health Organization | Signal Transduction | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Child, Preschool | Exons - genetics | Mutation, Missense - genetics | Young Adult | Ganglioglioma - genetics | Astrocytoma - pathology | Proto-Oncogene Proteins B-raf - genetics | Ganglioglioma - pathology | Adolescent | Adult | Nervous System Neoplasms - genetics | Retrospective Studies | Child | Nervous System Neoplasms - pathology | Medical colleges | Molecular genetics | Sarcoma | Neurons | Brain tumors | Oncology, Experimental | Melanoma | Thyroid diseases | Research | Codon | Gene mutations | Gliomas | Analysis | Genetic research | Genetic aspects | Cancer | Index Medicus | meningioma | Pediatrics | Exons | Glioblastoma | Clinical trials | Insertion | Adenoma | Neuronal-glial interactions | Missense mutation | Sheaths | Colon | Astrocytoma | Oncogenes | Peripheral nervous system | Astrocytes | Base pairs | Central nervous system diseases | Glioma | Pituitary | Codons | papillary thyroid carcinoma | Tumors
Journal Article
Cancer discovery, ISSN 2159-8274, 09/2018, Volume 8, Issue 9, pp. 1130 - 1141
BRAF hyperactivates ERK and signals as a RAF inhibitor-sensitive monomer. Although RAF inhibitors can produce impressive clinical responses in patients with... 
BRAF V600E | secondary mutation | dabrafenib | acquired resistance
Journal Article
CANCER, ISSN 0008-543X, 08/2013, Volume 119, Issue 15, pp. 2765 - 2770
BACKGROUND A point mutation (V600E) in the BRAF oncogene is a prognostic biomarker and may predict for nonresponse to anti-EGFR antibody therapy in patients... 
SURVIVAL | microsatellite instability | colon cancer | PREDICTIVE-VALUE | METASTATIC COLORECTAL-CANCER | STAGE-II | CETUXIMAB | BRAF(V600E) mutation | MELANOMA | ONCOLOGY | BRAF MUTATION | KRAS | immunohistochemistry | BRAF(V600E) protein | MISMATCH-REPAIR STATUS
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2012, Volume 13, Issue 11, pp. 1087 - 1095
Journal Article