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11/2012
Planar cell polarity (PCP) refers to the coordinated orientation, movement, or structure of cells within the plane of a tissue. Zebrafish PCP mutants such as... 
Tmem14a | 0369 | Vangl2 | 0379 | planar cell polarity | neural tube development | cilia | zebrafish | 0307 | Golgi trafficking
Dissertation
Current Opinion in Cell Biology, ISSN 0955-0674, 12/2018, Volume 55, pp. 96 - 103
The planar cell polarity (PCP) pathway controls a variety of morphological events across many species. During embryonic development, the PCP pathway regulates... 
GENES CELSR1 | PATHWAY | BRANCHING MORPHOGENESIS | PROTEIN VANGL2 | DYNAMICS | DIFFERENTIATION | CILIA | CELL BIOLOGY | Gene mutations | Embryonic development | Developmental biology
Journal Article
Developmental Biology, ISSN 0012-1606, 08/2019, Volume 452, Issue 1, pp. 21 - 33
The asymmetric localization of planar cell polarity (PCP) proteins is essential for the establishment of many planar polarized cellular processes, but the... 
GASTRULATION | HAIR-CELLS | CILIARY | PROTEIN | VANGL2 | EPITHELIAL-CELLS | DYNAMICS | CONVERGENT EXTENSION | DEVELOPMENTAL BIOLOGY | POLARIZATION | ASYMMETRIC LOCALIZATION | Proteins | Polymerization | Protein binding
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 3325 - 14
Fractures are a common comorbidity in children with the neural tube defect (NTD) spina bifida. Mutations in the Wnt/planar cell polarity (PCP) pathway... 
FRACTURE | MINERAL DENSITY | SKELETAL HEALTH | VANGL2 | NEURAL-TUBE DEFECTS | MOUSE MUTANTS | MULTIDISCIPLINARY SCIENCES | BRANCHING MORPHOGENESIS | CLOSURE | RISK | CHILDHOOD | Fibula | Transcription factors | Wnt protein | Bone (trabecular) | Osteoblasts | Spina bifida | Genetic variance | Signal transduction | Bone mass | Fractures | Tibia | Rodents | Osteoclasts | Polarity | Children | Mutation | Pax3 protein | Bone (cortical)
Journal Article
eLife, ISSN 2050-084X, 01/2020, Volume 9
Dynamic mechanical interactions between adhesion complexes and the cytoskeleton are essential for axon outgrowth and guidance. Whether planar cell polarity... 
Journal Article
DEVELOPMENT, ISSN 0950-1991, 11/2019, Volume 146, Issue 22, p. dev182188
Lateral zebrafish hypoblast cells initiate dorsal convergence near mid-gastrulation and exhibit non-polarized morphologies, limited cell-cell contact and... 
Vangl2 | MOVEMENTS | ZEBRAFISH | Migration | DEVELOPMENTAL BIOLOGY | PRIMORDIAL GERM-CELLS | PLASMA-MEMBRANE | Fibronectin | Protrusion | CADHERIN | Ezrin b | MORPHOGENESIS | EZRIN | DOWNSTREAM | Polarity
Journal Article
Current Biology, ISSN 0960-9822, 11/2019, Volume 29, Issue 21, pp. 3579 - 3587.e7
The development of mechanosensory epithelia, such as those of the auditory and vestibular systems, results in the precise orientation of mechanosensory hair... 
delta | lateral inhibition | bistability | Emx2 | planar cell polarity | neuromast | ASYMMETRY | VANGL2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | IDENTIFICATION | POLARIZATION | PLANAR POLARITY | CELL BIOLOGY
Journal Article
Development (Cambridge, England), ISSN 0950-1991, 11/2018, Volume 145, Issue 22, p. dev165472
During zebrafish gastrulation the planar cell polarity (PCP) protein Vang-like 2 (Vangl2) regulates the polarization of cells that are engaged in directed... 
Vangl2 | Gastrulation | Migration | Polarity | Zebrafish | Fibronectin | Protrusion | GASTRULATION MOVEMENTS | TRILOBITE | PLANAR CELL POLARITY | DEVELOPMENTAL BIOLOGY | IDENTIFICATION | ORGANIZATION | MORPHOGENESIS | CONVERGENT EXTENSION MOVEMENTS | MESODERM | GENES | PROTEINS
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 08/2009, Volume 106, Issue 34, pp. 14426 - 14431
Journal Article
Cerebral Cortex, ISSN 1047-3211, 02/2019, Volume 29, Issue 2, pp. 505 - 516
Abstract SEC14 and Spectrin domain-1 (Sestd1) is a synapse protein that exhibits a striking shift from the presynaptic to postsynaptic space as neurons mature... 
EMBRYONIC-DEVELOPMENT | ANTAGONIST | hippocampus | ACTIN | pyramidal | CATENIN | DAPPER | NEUROSCIENCES | DENSITY | VANGL2 | NEURONS | projection | GTPase | glutamate | PCP PATHWAY | DACT1
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 03/2015, Volume 30, Issue 3, pp. 423 - 435
ABSTRACT Exposure of bone to dynamic strain increases the rate of division of osteoblasts and also influences the directional organization of the cellular and... 
PLANAR CELL POLARITY | VANGL2 | WNT SIGNALING | MECHANICAL STRAIN | OSTEOBLASTS |