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Clinical Infectious Diseases, ISSN 1058-4838, 11/2018, Volume 67, Issue 12, pp. 1890 - 1896
A preconceptional cohort of 275 nulligravidae was established in Benin, and 68 confirmed pregnancies were followed up until delivery. Women infected with... 
AFRICA | INFECTIOUS DISEASES | preconception | SULFADOXINE-PYRIMETHAMINE | pregnancy | genotypes | VAR2CSA | MICROBIOLOGY | ANEMIA | IMMUNOLOGY | malaria
Journal Article
Journal Article
Emerging Infectious Diseases, ISSN 1080-6040, 2015, Volume 21, Issue 5, pp. 813 - 823
Placental malaria is caused by Plasmodium falciparum infected erythrocytes that bind to placental tissue. Binding is mediated by VAR2CSA, a parasite antigen... 
ADHESION | WOMEN | INFECTIOUS DISEASES | FALCIPARUM-INFECTED ERYTHROCYTES | PLASMODIUM-FALCIPARUM | CHONDROITIN SULFATE-A | VAR2CSA PROTEIN | BIRTH-WEIGHT | CROSS-REACTIVE ANTIBODIES | IMMUNOLOGY | BINDING | DOMAINS | Antigens, Protozoan - immunology | Follow-Up Studies | Immunoglobulin G - blood | Humans | Infant | Plasmodium falciparum - immunology | Young Adult | Antibodies, Protozoan - blood | Antibody Specificity - immunology | Pregnancy Complications, Parasitic - parasitology | Immunoglobulin G - immunology | Malaria - epidemiology | Malaria, Falciparum - epidemiology | Adult | Female | Infant, Newborn | Erythrocytes - immunology | Antibodies, Protozoan - immunology | Malaria - immunology | Risk Factors | Patient Outcome Assessment | Pregnancy | Benin - epidemiology | Malaria, Falciparum - parasitology | Pregnancy Complications, Parasitic - immunology | Malaria - parasitology | Malaria, Falciparum - immunology | Protein Binding | Pregnancy Complications, Parasitic - epidemiology | Placenta - parasitology | Erythrocytes - parasitology | Pregnancy Outcome | Malaria | Infants (Premature) | Anemia | Growth | Antibodies | Sulfates | Infection | Viral antibodies | Anemia in pregnancy | Plasmodium falciparum | Pregnant women | Analysis | Fetus | Health aspects | Benin | erythrocytes | outcomes | placental malaria | pregnancy | VAR2CSA | parasites | Protective Antibodies against Placental Malaria and Poor Outcomes during Pregnancy, Benin | antibodies | Research | malaria | variant surface antigen 2 chondroitin sulfate
Journal Article
Cellular Microbiology, ISSN 1462-5814, 06/2015, Volume 17, Issue 6, pp. 819 - 831
Acquired protection from Plasmodium falciparum malaria takes years to develop, probably reflecting the ability of the parasites to evade immunity. A recent... 
CHONDROITIN SULFATE | PFEMP1 | SURFACE | VAR2CSA | MALARIA PARASITE | MICROBIOLOGY | INFECTED ERYTHROCYTES | IMMUNOGLOBULIN BINDING | VARIANT | EXPRESSION | ANTIGEN | CELL BIOLOGY
Journal Article
Journal Article
JOURNAL OF PROTEOME RESEARCH, ISSN 1535-3893, 11/2019, Volume 18, Issue 11, pp. 3831 - 3839
Plasmodium falciparum variant antigens named erythrocyte membrane protein 1 (PfEMP1) are important targets for developing a protective immunity to malaria... 
Plasmodium falciparum proteomics | ANTIBODIES | ERYTHROCYTE-MEMBRANE PROTEIN-1 | BIOCHEMICAL RESEARCH METHODS | INFECTED ERYTHROCYTES | LEVEL | PREGNANCY-ASSOCIATED MALARIA | variant antigens | DISEASE | VAR2CSA | TARGETS | proteogenomics | EXPRESSION | PfEMP1
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 04/2010, Volume 397, Issue 3, pp. 826 - 834
malaria remains one of the world's leading causes of human suffering and poverty. Each year, the disease takes 1–3 million lives, mainly in sub-Saharan Africa.... 
CSA | VAR2CSA | vaccine | malaria | PfEMP1 | PROTEOGLYCANS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INFECTED ERYTHROCYTES | ADHERENCE | PREGNANCY-ASSOCIATED MALARIA | CHONDROITIN-SULFATE-A | GENE | SURFACE | CYTOADHERENCE | CYTOADHESION | DOMAINS | Recombinant Proteins - metabolism | Surface Plasmon Resonance | Malaria, Falciparum - genetics | Antigens, Protozoan - immunology | Chondroitin Sulfates - metabolism | Enzyme-Linked Immunosorbent Assay | Antibodies, Protozoan - immunology | Glycosaminoglycans - metabolism | Rats | Recombinant Proteins - genetics | Plasmodium falciparum - immunology | Recombinant Proteins - isolation & purification | Antigens, Protozoan - metabolism | Animals | Flow Cytometry | Plasmodium falciparum - genetics | Cloning, Molecular | Erythrocytes - metabolism | Malaria, Falciparum - immunology | Malaria, Falciparum - metabolism | Antigens, Protozoan - genetics | Erythrocytes - parasitology | Antibodies, Protozoan - metabolism | Plasmodium falciparum | Proteoglycans | Glycosaminoglycans | Malaria | Pregnant women | Immunoglobulin G | Fluorescence | Cross infection | Nosocomial infections | Chromatography | Protein binding | DBL, Duffy-binding-like | IE, infected erythrocyte | IEX, ion exchange | CSC, chondroitin sulphate C | HSPG, heparan sulphate proteoglycan | CSA, chondroitin sulphate A | PAM, pregnancy-associated malaria | GAG, glycosaminoglycan | CSPG, chondroitin sulphate proteoglycan | IMAC, immobilized metal ion affinity chromatography | AC, affinity chromatography | FV2, full-length VAR2CSA | PfEMP1, Plasmodium falciparum erythrocyte membrane protein 1 | CSPG-h, human chondroitin sulphate proteoglycan | MFI, mean fluorescence intensity | CSPG-b, bovine chondroitin sulphate proteoglycan
Journal Article
INFECTION AND IMMUNITY, ISSN 0019-9567, 10/2015, Volume 83, Issue 10, pp. 3972 - 3981
The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) adhesive proteins expressed on the surfaces of infected erythrocytes (IEs) are of key... 
PFEMP1 | INFECTIOUS DISEASES | ANTIGENIC VARIATION | SEVERE MALARIA | VAR GENE | SEQUENCE | VAR2CSA | SURFACE | INFECTED ERYTHROCYTES | IMMUNOLOGY | EXPRESSION | EPITOPES
Journal Article
Trends in Parasitology, ISSN 1471-4922, 03/2019, Volume 35, Issue 3, pp. 178 - 181
Malaria research has led to the discovery of oncofetal chondroitin sulfate, which appears to be shared between placental trophoblasts and cancer cells and can... 
VAR2CSA | cancer | oncofetal chondroitin sulfate | placental malaria | CHONDROITIN SULFATE | PLASMODIUM-FALCIPARUM | PARASITOLOGY | Plasmodium falciparum | Glycosaminoglycans | Malaria | Sulfates | Cancer | Protein binding
Journal Article
International journal of cancer, ISSN 0020-7136, 4/2017, Volume 140, Issue 7, pp. 1597 - 1608
Burkitt lymphoma (BL) is a malignant disease, which is frequently found in areas with holoendemic Plasmodium falciparum malaria. We have previously found that... 
CSA | Plasmodium falciparum | Chondroitin Sulfate A | chondroitin sulfate proteoglycan | VAR2CSA | Burkitt Lymphoma | malaria | Cancer
Journal Article
Vaccine, ISSN 0264-410X, 2016, Volume 35, Issue 4, pp. 610 - 618
Journal Article
Cancer Cell, ISSN 1535-6108, 10/2015, Volume 28, Issue 4, pp. 500 - 514
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 5/2014, Volume 209, Issue 9, pp. 1408 - 1417
Journal Article