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animals (44) 44
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renal medullary blood flow (5) 5
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arterioles (4) 4
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physiological aspects (4) 4
pressure-natriuresis (4) 4
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descending vasa recta (3) 3
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erythrocytes - metabolism (3) 3
expression (3) 3
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inositol 1,4,5-trisphosphate receptors - metabolism (3) 3
k+ conductance (3) 3
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1. Ca2+ Signalling in Pericytes
by Burdyga, Theodor and Borysova, Lyudmyla
Advances in experimental medicine and biology, ISSN 0065-2598, 2018, Volume 1109, pp. 95 - 109
Microcirculation is the generic name for the finest level of the circulatory system and consists of arteriolar and venular networks located upstream and... 
Microvascular networks | Conducted vasoconstriction | Gap junctions | Vasoconstriction | Postcapillary venules | wave | Ca2+ wave | Precapillary arterioles | Conducted vasodilation | Pericytes | Ca2+ oscillations | Ca2+ signalling | Capillaries | oscillations | signalling | RAT | BLOOD-FLOW | CELL BIOLOGY | CAPILLARY PERICYTES | DESCENDING VASA-RECTA | SUBMUCOSAL VENULES | CALCIUM | RETINAL MICROVASCULATURE | SMOOTH-MUSCLE-CELLS
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2. Pericytes in Type 2 Diabetes
by Hayes, KL
2019, Advances in Experimental Medicine and Biology, Volume 1147, 14
Pericytes are mural cells that are found ubiquitously throughout the microvasculature. Their main physiological roles are to support endothelial cells,... 
MEDICINE, RESEARCH & EXPERIMENTAL | Hyperinsulinemia | Blood-nerve barrier | Retinopathy | Dyslipidemia | Peripheral artery disease | Neuropathy | CELL BIOLOGY | Mural cell | Hyperglycemia | Advanced glycation end products | Blood-retina barrier | MOUSE MODEL | COMPLICATIONS | GLYCATION END-PRODUCTS | OXIDATIVE STRESS | STEM-CELLS | DEGENERATION | SKELETAL-MUSCLE | Nephropathy | Beta cell | BIOLOGY | VASA-RECTA | Microvasculature | TIGHT JUNCTIONAL MOLECULES | KIDNEY
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3. Full Text Calcium Signalling in Pericytes
by Burdyga, Theodor and Borysova, Lyudmyla
Journal of Vascular Research, ISSN 1018-1172, 08/2014, Volume 51, Issue 3, pp. 190 - 199
Recent advances in pericyte research have contributed to our understanding of the physiology and pathophysiology of microvessels. The microvasculature consists... 
Review | Venules | Arterioles | Microvascular networks | Pericytes | Myocytes | Capillaries | Ca 2+ signalling | ARTERIOLAR DILATION | PHYSIOLOGY | POTASSIUM CHANNELS | INTRACELLULAR CALCIUM | CONTRACTILE PROTEINS | VASOACTIVE SIGNAL | HYPERPOLARIZING FACTOR | DESCENDING VASA-RECTA | CONDUCTED VASODILATION | RETINAL MICROVASCULATURE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | Ca2+ signalling | Muscle Cells - physiology | Animals | Pericytes - drug effects | Calcium - metabolism | Calcium Signaling - physiology | Humans | Pericytes - ultrastructure | Receptors, G-Protein-Coupled - agonists | Pericytes - physiology | Sarcoplasmic Reticulum - secretion | Endothelium, Vascular - physiology | Receptors, G-Protein-Coupled - physiology
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4. Full Text Renal pericytes: regulators of medullary blood flow
by Kennedy‐Lydon, T. M and Crawford, C and Wildman, S. S. P and Peppiatt‐Wildman, C. M
Acta Physiologica, ISSN 1748-1708, 02/2013, Volume 207, Issue 2, pp. 212 - 225
Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta... 
medulla | cross‐talk | pericyte | blood flow | Pericyte | Medulla | Cross-talk | Blood flow | JUXTAMEDULLARY MICROVASCULAR RESPONSES | PHYSIOLOGY | cross-talk | RAT-KIDNEY | NITRIC-OXIDE SYNTHASE | ANGIOTENSIN-II | INTERSTITIAL HYDROSTATIC-PRESSURE | DESCENDING VASA-RECTA | ARTERIAL-PRESSURE | L-ARGININE | CHRONIC KIDNEY-DISEASE | THICK ASCENDING LIMB | Renal Circulation - physiology | Kidney Medulla - cytology | Animals | Pericytes - physiology | Humans | Kidney Medulla - blood supply | Reviews
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5. Full Text Spontaneous activity in the microvasculature of visceral organs: role of pericytes and voltage‐dependent Ca2+ channels
by Hashitani, Hikaru and Lang, Richard J
The Journal of Physiology, ISSN 0022-3751, 02/2016, Volume 594, Issue 3, pp. 555 - 565
The microvasculature plays a primary role in the interchange of substances between tissues and the circulation. In visceral organs that undergo considerable... 
PHYSIOLOGY | PIG GASTRIC PYLORUS | CALCIUM-CHANNELS | DESCENDING VASA-RECTA | URINARY-BLADDER | MOUSE RENAL PELVIS | SMALL-INTESTINE | SMOOTH-MUSCLE-CELLS | GUINEA-PIG | T-TYPE | NEUROSCIENCES | INTERSTITIAL-CELLS | Gastrointestinal system | Rodents | Adenosine triphosphatase | Cardiovascular Physiology | Topical Review | Cellular and molecular Physiology | Vasculature | Topical Reviews
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6. Full Text Nonsteroidal anti-inflammatory drugs alter vasa recta diameter via pericytes
by Kennedy-Lydon, Teresa and Crawford, Carol and Wildman, Scott S and Peppiatt-Wildman, Claire M
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 09/2015, Volume 309, Issue 7, pp. F648 - F657
We have previously shown that vasa recta pericytes are known to dilate vasa recta capillaries in the presence of PGE(2) and contract vasa recta capillaries... 
Vasa recta | Pericyte | Medulla | Nonsteroidal anti-inflammatory drugs | nonsteroidal anti-inflammatory drugs | medulla | PHYSIOLOGY | pericyte | CONTAINING MICROVASCULATURE | RAT RETINA | vasa recta | ANGIOTENSIN-II | RENAL MEDULLARY MICROCIRCULATION | UROLOGY & NEPHROLOGY | INDUCED NEPHROTOXICITY | KIDNEY | INTRARENAL BLOOD-FLOW | THICK ASCENDING LIMB | PROSTAGLANDIN E | IN-SITU | Vasodilator Agents - pharmacology | Kidney Tubules - drug effects | Pericytes - drug effects | Nitric Oxide - pharmacology | Prostaglandins - pharmacology | Rats | Capillaries - drug effects | Male | Kidney Tubules - blood supply | Rats, Sprague-Dawley | Vasoconstriction - drug effects | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Animals | Drug Interactions | Renal Circulation - drug effects | Vasodilation - drug effects | In Vitro Techniques | Bradykinin - pharmacology | Medulla oblongata | Research | Indomethacin | Health aspects
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7. Full Text The evolving role of renal pericytes
by Peppiatt-Wildman, Claire M
Current Opinion in Nephrology and Hypertension, ISSN 1062-4821, 01/2013, Volume 22, Issue 1, pp. 10 - 16
PURPOSE OF REVIEWThe purpose of this review is to focus on the most recent developments in our understanding of the physiological and pathophysiological... 
kidney disease | vasa recta | pericyte | hypertension | medullary blood flow | PROGENITOR CELLS | MEDULLARY BLOOD-FLOW | ANGIOTENSIN-II | MECHANISMS | TUBULOVASCULAR CROSS-TALK | KIDNEY INJURY | NITRIC-OXIDE | UROLOGY & NEPHROLOGY | VASA-RECTA | PERIPHERAL VASCULAR DISEASE | IN-SITU | SUPEROXIDE TRANSPORT | Kidney Diseases - physiopathology | Animals | Signal Transduction | Fibrosis - etiology | Humans | Pericytes - cytology | Renal Circulation | Pericytes - physiology | Neovascularization, Pathologic - etiology | Hypertension - etiology | Kidney Medulla - blood supply
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8. Immune Functions and Properties of Resident Cells in the Heart and Cardiovascular System: Pericytes
by Kennedy-Lydon, T
2017, Advances in Experimental Medicine and Biology, Volume 1003, 11
ATHEROSCLEROTIC LESIONS | MEDICINE, RESEARCH & EXPERIMENTAL | CARDIAC & CARDIOVASCULAR SYSTEMS | ABNORMALITIES | VASA-RECTA DIAMETER | MICROVASCULAR PERICYTES | PROLIFERATION | MECHANISMS | IMMUNOLOGY | KIDNEY FIBROSIS | IN-VIVO | BLOOD-VESSELS | RETINAL PERICYTES
Book Chapter
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9. Full Text Effects of angiotensin II on the pericyte-containing microvasculature of the rat retina
by Hajime Kawamura and Masato Kobayashi and Qing Li and Shigeki Yamanishi and Kozo Katsumura and Masahiro Minami and David M Wu and Donald G Puro
The Journal of Physiology, ISSN 0022-3751, 12/2004, Volume 561, Issue 3, pp. 671 - 683
The aim of this study was to identify the mechanisms by which angiotensin II alters the physiology of the pericyte-containing microvasculature of the retina.... 
CELLS | PROTEIN-KINASE-C | PHYSIOLOGY | INTERCELLULAR COMMUNICATION | SENSITIVE K+ CURRENTS | PATCH-CLAMP | MICROVESSELS | VASA-RECTA PERICYTES | EXPRESSION | ATP | Membrane Potentials - drug effects | Angiotensin II - pharmacology | Calcium - pharmacology | Rats, Long-Evans | Rats | Capillaries - drug effects | Electric Conductivity | Protein Kinase C - antagonists & inhibitors | Retinal Vessels - drug effects | Pericytes - physiology | Phenanthridines - pharmacology | Vasoconstriction - drug effects | Retinal Vessels - physiology | Alkaloids | Calcium Channels - physiology | Animals | Calcium - physiology | Benzophenanthridines | In Vitro Techniques | Angiotensin II - physiology | Research Papers
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10. Full Text Sympathetic nerve-derived ATP regulates renal medullary vasa recta diameter via pericyte cells: a role for regulating medullary blood flow?
by Crawford, C and Wildman, SSP and Kelly, MC and Kennedy-Lydon, TM and Peppiatt-Wildman, CM
FRONTIERS IN PHYSIOLOGY, ISSN 1664-042X, 10/2016, Volume 7, p. 307
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of... 
NEURAL-CONTROL | PHYSIOLOGY | STIMULATION | KIDNEY IN-VIVO | RAT | pericytes | INNERVATION | MUSCLE | vasa recta | RELEASE | P2 receptors | ATP release | vasoconstriction | RECEPTORS | NORADRENALINE | kidney slice
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11. Full Text Inward rectifier currents in pericytes
by Loutzenhiser, Rodger
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 06/2006, Volume 290, Issue 6, pp. R1598 - R1600
RECTIFYING POTASSIUM CHANNELS | SMOOTH-MUSCLE | PHYSIOLOGY | DESCENDING VASA-RECTA | MICROCIRCULATION | ANGIOTENSIN-II | AFFERENT | BLOOD-FLOW | ARTERIOLES | Capillaries - physiology | Potassium - metabolism | Animals | Capillaries - cytology | Pericytes - metabolism | Potassium Channels, Inwardly Rectifying - physiology | Electrophysiology | Rats | Pericytes - physiology | Kidney Medulla - blood supply
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12. Full Text Sympathetic nerve-derived ATP regulates renal medullary blood flow via vasa recta pericytes
by Scott S Wildman
Frontiers in Physiology, 10/2013, Volume 4
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of... 
Pericytes | vasa recta | P2 receptors | kidney slice | Vasoconstriction | ATP release
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13. Full Text Cellular Mechanisms of Tissue Fibrosis. 3. Novel mechanisms of kidney fibrosis
by Gabriela Campanholle and Giovanni Ligresti and Sina A. Gharib and Jeremy S. Duffield
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 04/2013, Volume 304, Issue 7, pp. 591 - 603
Chronic kidney disease, defined as loss of kidney function for more than three months, is characterized pathologically by glomerulosclerosis, interstitial... 
Pericyte | Chronic kidney disease | Inflammation | Myofibroblast | Fibrosis | chronic kidney disease | SIGNALING PATHWAYS | PHYSIOLOGY | pericyte | myofibroblast | MICROVASCULAR RAREFACTION | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | RENAL FIBROSIS | inflammation | INTERSTITIAL FIBROSIS | NITRIC-OXIDE | VASA-RECTA | fibrosis | GROWTH-FACTOR | MICRORNA SIGNATURE | PERICYTE-MYOFIBROBLAST TRANSITION | Myofibroblasts - pathology | Animals | Kidney - pathology | Pericytes - pathology | Kidney - cytology | Fibrosis - pathology | Mesenchymal Stromal Cells - pathology | Renal Insufficiency, Chronic - pathology | Physiological aspects | Fibroblasts | Development and progression | Chronic kidney failure | Health aspects | Themes
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14. Full Text Evidence for the presence of smooth muscle α-actin within pericytes of the renal medulla
by Frank Park and David L. Mattson and Lou A. Roberts and Allen W. Cowley, Jr
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, ISSN 0363-6119, 11/1997, Volume 273, Issue 5, pp. 1742 - 1748
This study was designed to determine whether smooth muscle α-actin mRNA and smooth muscle α-actin contractile protein elements were present within the renal... 
Immunohistochemistry | Renal medullary blood flow | Descending vasa recta | Western blot analysis | Microdissection | Reverse transcription-polymerase chain reaction | Actins - biosynthesis | Muscle, Smooth, Vascular - metabolism | Rats | Male | DNA Primers | Rats, Sprague-Dawley | Blotting, Western | Kidney Medulla - blood supply | Muscle, Smooth | RNA, Messenger - biosynthesis | Animals | Arterioles - metabolism | Actins - analysis | Transcription, Genetic | Capillaries - metabolism | Usage | Messenger RNA | Western immunoblotting | Actin | Analysis | Research | Dissection
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15. Pericyte regulation of renal medullary blood flow
by Pallone, Thomas L and Silldorff, Erik P
Experimental Nephrology, ISSN 1018-7782, 2001, Volume 9, Issue 3, pp. 165 - 170
Pericytes are contractile smooth muscle-like cells that surround descending vasa recta (DVR) and provide their capability for vasomotion. The importance of the... 
Vasa recta | Microcirculation | Oxygen | Nitric oxide | Kidney | kidney | nitric oxide | ADENOSINE | UROLOGY & NEPHROLOGY | vasa recta | microcirculation | oxygen | Vasoconstrictor Agents - pharmacology | Vasodilator Agents - pharmacology | Pericytes - drug effects | Kidney Cortex - blood supply | Humans | Vasomotor System - drug effects | Pericytes - ultrastructure | Microcirculation - anatomy & histology | Pericytes - physiology | Forecasting | Microcirculation - drug effects | Oxygen - metabolism | Kidney Medulla - blood supply | Vasodilator Agents - blood | Vasomotor System - anatomy & histology | Animals | Vasoconstrictor Agents - blood | Kidney Concentrating Ability | Kidney Medulla - anatomy & histology | Kidney Medulla - metabolism | Renal Circulation - drug effects
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16. Full Text Disruption of vascular Ca2+-activated chloride currents lowers blood pressure
by Heinze, Christoph and Seniuk, Anika and Sokolov, Maxim V and Huebner, Antje K and Klementowicz, Agnieszka E and Szijártó, István A and Schleifenbaum, Johanna and Vitzthum, Helga and Gollasch, Maik and Ehmke, Heimo and Schroeder, Björn C and Hübner, Christian A
Journal of Clinical Investigation, ISSN 0021-9738, 02/2014, Volume 124, Issue 2, pp. 675 - 686
High blood pressure is the leading risk factor for death worldwide. One of the hallmarks is a rise of peripheral vascular resistance, which largely depends on... 
MEDICINE, RESEARCH & EXPERIMENTAL | PHYSIOLOGY | DESCENDING VASA-RECTA | CEREBRAL-ARTERY | CALCIUM | ION-CHANNEL | SMOOTH-MUSCLE-CELLS | ANGIOTENSIN-II | TMEM16A | HYPERTENSION | PERICYTES | Anoctamin-1 | Retina - metabolism | Humans | Electrophysiology | Mesenteric Arteries - pathology | Estrogen Antagonists - pharmacology | Hypertension - drug therapy | Neoplasm Proteins - metabolism | Brain - metabolism | Time Factors | Cloning, Molecular | HEK293 Cells | Blood Pressure - drug effects | Blood Pressure - physiology | Membrane Potentials - drug effects | Vasoconstrictor Agents - pharmacology | Vascular Resistance | Mice, Inbred C57BL | Pericytes - metabolism | Muscle, Smooth, Vascular - cytology | Hypertension - physiopathology | Mice, Knockout | Chloride Channels - metabolism | Arterioles - pathology | Animals | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Tamoxifen - pharmacology | Mice | DNA, Complementary - metabolism
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17. Full Text A novel mechanism for regulation of retinal blood flow by lactate: Gap junctions, hypoxia, and pericytes
by Lombard, Julian H
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 03/2006, Volume 290, Issue 3, pp. H921 - H922
CONDUCTANCE | PERIPHERAL VASCULAR DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | RAT | DESCENDING VASA-RECTA | Hemostasis - drug effects | Retina - drug effects | Cell Hypoxia - drug effects | Cell Hypoxia - physiology | Hemostasis - physiology | Pericytes - drug effects | Humans | Feedback - physiology | Retinal Vessels - drug effects | Pericytes - physiology | Retinal Vessels - physiology | Retina - physiology | Feedback - drug effects | Animals | Gap Junctions - physiology | Gap Junctions - drug effects | Lactic Acid - pharmacology | Blood Flow Velocity - physiology | Blood Flow Velocity - drug effects
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