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Oncogene, ISSN 0950-9232, 08/2015, Volume 34, Issue 33, pp. 4311 - 4319
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2015, Volume 290, Issue 28, pp. 17485 - 17494
Journal Article
Chest, ISSN 0012-3692, 06/2017, Volume 151, Issue 6, pp. 1302 - 1310
Background Animal and cellular studies support the importance of autophagy inhibition in lymphangioleiomyomatosis (LAM). In a cohort of subjects with LAM, we... 
autophagy | VEGF-D | lymphangioleiomyomatosis | FEV | sirolimus | ADVANCED SOLID TUMORS | SAFETY | PANCREATIC ADENOCARCINOMA | 6-MINUTE-WALK TEST | COMBINATION | IMPORTANT DIFFERENCE | HYDROXYCHLOROQUINE | WOMEN | TUBEROUS SCLEROSIS COMPLEX | RESPIRATORY SYSTEM | PULMONARY LYMPHANGIOLEIOMYOMATOSIS | FEV1 | CRITICAL CARE MEDICINE | Lymphangioleiomyomatosis - blood | Sirolimus - therapeutic use | Enzyme-Linked Immunosorbent Assay | Humans | Immunosuppressive Agents - therapeutic use | Lymphangioleiomyomatosis - physiopathology | Middle Aged | Treatment Outcome | Lymphangioleiomyomatosis - drug therapy | Diarrhea - chemically induced | Autophagy | Mucositis - chemically induced | Hydroxychloroquine - administration & dosage | Enzyme Inhibitors - administration & dosage | Forced Expiratory Volume | Vital Capacity | Vascular Endothelial Growth Factor D - blood | Adult | Female | Aged | Walk Test | Headache - chemically induced | Women | Dosage and administration | Hydroxychloroquine | Lymphatic diseases | Drug therapy | Health aspects | Index Medicus | Abridged Index Medicus | 6-MWD, 6-min walk distance | Dlco, diffusion coefficient for carbon monoxide | TSC, tuberous sclerosis complex | VEGF-D, vascular endothelial growth factor D | MTD, maximal tolerated dose | NCI, National Cancer Institute | DLT, dose-limiting toxicity | AML, angiomyolipoma | Diffuse Lung Disease | LAM, lymphangioleiomyomatosis | SGRQ, St George’s Respiratory Questionnaire
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 01/2015, Volume 64, Issue 1, pp. 200 - 212
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 386, pp. 12 - 23
Abstract Triple-negative breast cancer (TNBC) are characterized by high vascularity and frequent metastasis. Here, we found that activation of G... 
Hematology, Oncology and Palliative Medicine | Angiogenesis | NF-κB | G-1 | TNBC | GPER | STEM-CELLS | VEGF | PROLIFERATION | CELL-GROWTH | COUPLED RECEPTOR 30 | EPITHELIAL-MESENCHYMAL TRANSITION | IN-VITRO | NF-kappa B | ONCOLOGY | INFLAMMATION | NF-KAPPA-B | EXPRESSION | Neovascularization, Physiologic - drug effects | Phosphorylation | Receptors, Estrogen - metabolism | Interleukin-6 - antagonists & inhibitors | Human Umbilical Vein Endothelial Cells - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Middle Aged | Neovascularization, Pathologic | NF-kappa B - metabolism | Vascular Endothelial Growth Factor A - metabolism | Receptors, G-Protein-Coupled - agonists | Triple Negative Breast Neoplasms - drug therapy | Quinolines - pharmacology | Dose-Response Relationship, Drug | Time Factors | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Triple Negative Breast Neoplasms - pathology | Female | Antineoplastic Agents - pharmacology | Binding Sites | Interleukin-6 - metabolism | STAT3 Transcription Factor - metabolism | Promoter Regions, Genetic | NF-kappa B - antagonists & inhibitors | Human Umbilical Vein Endothelial Cells - drug effects | Interleukin-6 - genetics | Neoplasm Invasiveness | Cyclopentanes - pharmacology | Antibodies - pharmacology | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Animals | Triple Negative Breast Neoplasms - genetics | NF-kappa B - genetics | Signal Transduction - drug effects | Tumor Burden - drug effects | Mice, Nude | Triple Negative Breast Neoplasms - metabolism | Cell Line, Tumor | Index Medicus
Journal Article
Journal Article
International Journal of Oncology, ISSN 1019-6439, 12/2014, Volume 45, Issue 6, pp. 2267 - 2277
Leiomyosarcomas remain challenging tumors to manage and novel therapy strategies besides radiation and conventional chemotherapy are needed. Targeting... 
leiomyosarcoma | VEGF | tumor | angiogenesis | receptor tyrosine kinase | VEGF receptor | PTK787/ZK222584 | small molecule inhibitor | Angiogenesis | Leiomyosarcoma | Receptor tyrosine kinase | Tumor | Small molecule inhibitor | FACTOR VEGF | MIGRATION | PHASE-III | METASTATIC COLORECTAL ADENOCARCINOMA | CANCER | ANTIANGIOGENIC THERAPY | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | ENDOTHELIAL GROWTH-FACTOR | Human Umbilical Vein Endothelial Cells | Vascular Endothelial Growth Factor A - biosynthesis | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Vascular Endothelial Growth Factor Receptor-3 - biosynthesis | Humans | Proto-Oncogene Proteins c-sis - administration & dosage | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Angiogenesis Inhibitors - administration & dosage | Leiomyosarcoma - genetics | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Vascular Endothelial Growth Factor Receptor-2 - biosynthesis | Gene Expression Regulation, Neoplastic - drug effects | Vascular Endothelial Growth Factor A - administration & dosage | Proto-Oncogene Proteins c-sis - biosynthesis | Phthalazines - administration & dosage | Pyridines - administration & dosage | Leiomyosarcoma - pathology | Vascular Endothelial Growth Factor Receptor-1 - biosynthesis | Cell Movement - drug effects | Protein Kinase Inhibitors - administration & dosage | Receptor Protein-Tyrosine Kinases - genetics | Signal Transduction - drug effects | Neovascularization, Pathologic - drug therapy | Cell Line, Tumor | Leiomyosarcoma - drug therapy | Neovascularization, Pathologic - genetics | Vascular Endothelial Growth Factor Receptor-3 - antagonists & inhibitors | Physiological aspects | Research | Angiogenesis inhibitors | Drug therapy | Vascular endothelial growth factor | Health aspects | Biotechnology | Laboratories | Cloning | Clinical trials | Metastasis | Kinases | Cancer therapies | Cell adhesion & migration | Studies | Cell growth | Chemotherapy | Medical prognosis | Ligands | Growth factors | Veins & arteries | Apoptosis
Journal Article
Journal Article