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1. Full Text VEGFR2 promotes tumorigenesis and metastasis in a pro-angiogenic-independent way in gastric cancer 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 06 Biological Sciences 0601 Biochemistry and Cell Biology
by Lian, Lian and Li, Xiang-Li and Xu, Meng-Dan and Li, Xian-Min and Wu, Meng-Yao and Zhang, Yan and Tao, Min and Li, Wei and Shen, Xiao-Ming and Zhou, Chong and Jiang, Min
BMC Cancer, 02/2019, Volume 19, Issue 1, pp. 479 - 489
VEGFR2 | VTN | Gastric cancer
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2. Full Text Cooperation between integrin ανβ3 and VEGFR2 in angiogenesis
by Somanath, Payaningal R and Malinin, Nikolay L and Byzova, Tatiana V
Angiogenesis, ISSN 0969-6970, 06/2009, Volume 12, Issue 2, pp. 177 - 185
VEGFR2 | Angiogenesis | Alpha v beta 3 | Integrin
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3. Full Text VEGFR2 expression in head and neck squamous cell carcinoma cancer cells mediates proliferation and invasion
by Xu, Hui-Min and Zhu, Jian-Guo and Gu, Lian and Hu, Song-Qun and Wu, Hao
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2016, Volume 17, Issue 4, pp. 2217 - 2221
VEGFR2 | Proliferation | HNSCC | Invasion
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4. Full Text Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis
by Huang, Zhi and Zhao, Borui and Qin, Zhongxiang and Li, Yongtao and Wang, Tianqi and Zhou, Wei and Zheng, Jianyu and Yang, Shengyong and Shi, Yi and Fan, Yan and Xiang, Rong
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2019, Volume 181, pp. 111541 - 111541
Based on the significantly synergistic effects of CDK4 and VEGFR2 inhibitors on growth of cancer cells, a series of novel multi-kinase inhibitors targeting... 
VEGFR2 | Inhibitor | CDK4 | Cancer | Index Medicus
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5. Full Text Genetic Reduction of VEGFR2 Rescues Aberrant Angiogenesis Caused by Epsin Deficiency
by Tessneer, Kandice L and Pasula, Satish and Cai, Xiaofeng and Dong, Yunzhou and McManus, John and Liu, Xiaolei and Yu, Lili and Hahn, Scott and Chang, Baojun and Chen, Yiyuan and Griffin, Courtney and Xia, Lijun and Adams, Ralf H and Chen, Hong
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2/2014, Volume 34, Issue 2, pp. 331 - 337
VEGFR2 | Angiogenesis | Epsin
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6. Full Text Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide (pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor
by Harris, PA and Boloor, A and Cheung, M and Kumar, R and Crosby, RM and Davis-Ward, RG and Epperly, AH and Hinkle, KW and Hunter, RN and Johnson, JH and Knick, VB and Laudeman, CP and Luttrell, DK and Mook, RA and Nolte, RT and Rudolph, SK and Szewczyk, JR and Truesdale, AT and Veal, JM and Wang, L and Stafford, JA
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 08/2008, Volume 51, Issue 15, pp. 4632 - 4640
Inhibition of the vascular endothelial growth factor (VEGF) signaling pathway has emerged as one of the most promising new approaches for cancer therapy. We... 
VEGFR2 | CHEMISTRY, MEDICINAL | EFFICACY | TYROSINE KINASE INHIBITOR | ANGIOGENESIS INHIBITOR | ANTITUMOR
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7. Full Text Protein Tyrosine Phosphatase, Receptor Type B (PTPRB) Inhibits Brown Adipocyte Differentiation through Regulation of VEGFR2 Phosphorylation
by Ji Soo Kim and and Won Kon Kim and Kyoung-jin Oh and Eun-woo Lee and Baek Soo Han and Sang Chul Lee and Kwang-hee Bae
Journal of Microbiology and Biotechnology, ISSN 1017-7825, 2019, Volume 29, Issue 4, p. 645
Brown adipocytes have an important role in the regulation of energy balance through uncoupling protein-1 (UCP-1)-mediated nonshivering thermogenesis. Although... 
Brown adipogenesis | VEGFR2 | PTPRB | obesity
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8. Full Text Loss of osteoglycin promotes angiogenesis in limb ischaemiamousemodels viamodulation of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 signalling pathway
by Wu, Qi-Hong and Ma, Yu and Ruan, Cheng-Chao and Yang, Yan and Liu, Xin-He and Ge, Qian and Kong, Ling-Ran and Zhang, Ji-Wei and Yan, Chen and Gao, Ping-Jin
Cardiovascular Research, ISSN 0008-6363, 01/2017, Volume 113, Issue 1, pp. 70 - 80
VEGFR2 | Angiogenesis | Extracellular matrix | Osteoglycin | VEGF
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9. Full Text VEGF-C as a putative therapeutic target in cancer
by Michaelsen, Signe R and Poulsen, Hans S and Hamerlik, Petra
Oncotarget, ISSN 1949-2553, 06/2019, Volume 10, Issue 40, pp. 3988 - 3990
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10. Full Text β 3 Integrin promotes long-lasting activation and polarization of vascular endothelial growth factor receptor 2 by immobilized ligand
by Ravelli, Cosetta and Grillo, Elisabetta and Corsini, Michela and Coltrini, Daniela and Presta, Marco and Mitola, Stefania
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 10/2015, Volume 35, Issue 10, pp. 2161 - 2171
VEGFR2 | Angiogenesis | Lipid rafts | Gremlin | Integrins
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11. Full Text Synthesis, molecular modeling and biological evaluation of 4-alkoxyquinazoline derivatives as novel inhibitors of VEGFR2
by Lu, Liang and Zhao, Ting-Ting and Liu, Tian-Bao and Sun, Wen-Xue and Xu, Chen and Li, Dong-Dong and Zhu, Hai-Liang
Chemical and Pharmaceutical Bulletin, ISSN 0009-2363, 2016
A series of novel quinazoline derivatives have been designed and synthesized, and their inhibitory activities have also been tested against A549 (carcinomic... 
VEGFR2 | Schiff’s base | Quinazoline | Anticancer
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12. Preparation of VEGFR2 targeted ultrasound microbubbles by freeze-drying and targeting study in vitro
by Zhang, Huan and Peng, Yu-Lan and Wang, Hong and Huang, Jian-Bo and Yan, Feng
Journal of Sichuan University (Medical Science Edition), ISSN 1672-173X, 11/2018, Volume 49, Issue 6, pp. 955 - 959
VEGFR2 | Targeted microbubbles | Freeze-drying
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13. Full Text Curcumolide, a unique sesquiterpenoid from Curcuma wenyujin displays anti-angiogenic activity and attenuates ischemia-induced retinal neovascularization
by Lin, Weiwei and Tu, Hongfeng and Zhu, Yao and Guan, Yijian and Liu, Hui and Ling, Wei and Yan, Pengcheng and Dong, Jianyong
Phytomedicine, ISSN 0944-7113, 11/2019, Volume 64, pp. 152923 - 152923
Targeting vascular endothelial growth factor is a common treatment strategy for neovascular eye disease, a leading cause of visual impairment and blindness.... 
Endothelial cell apoptosis | Curcumolide | Retinal neovascularization | VEGFR2 signaling | Index Medicus
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14. Full Text Selective targeting of adenovirus to αvβ3 integrins, VEGFR2 and Tie2 endothelial receptors by angio-adenobodies
by Haisma, Hidde J and Kamps, Gera K and Bouma, Arend and Geel, Tessa M and Rots, Marianne G and Kariath, Anu and Bellu, Anna Rita
International Journal of Pharmaceutics, ISSN 0378-5173, 05/2010, Volume 391, Issue 1-2, pp. 155 - 161
Tumor angiogenesis is a prominent mechanism, driving the development and progression of solid tumors and the formation of cancer cell metastasis. Newly formed... 
VEGFR2 | Angiogenesis | Adenovirus | Tie2 | Integrins
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15. Full Text Neuroendocrine Carcinoma of the Stomach: A Response to Combination Chemotherapy Consisting of Ramucirumab Plus Paclitaxel
by Matsubara, Yuki and Ando, Takayuki and Hosokawa, Ayumu and Mihara, Hiroshi and Takagi, Hiroaki and Nakata, Naokatsu and Yoshita, Hiroki and Nanjo, Sohachi and Kajiura, Shinya and Fujinami, Haruka and Sugiyama, Toshiro
Internal Medicine, ISSN 0918-2918, 2018
Extrapulmonary neuroendocrine carcinoma (NEC) is a rare disease, and there is no standard chemotherapy. A 73-year-old man was diagnosed with advanced gastric... 
VEGFR2 | paclitaxel | ramucirumab | neuroendocrine carcinoma | chemotherapy
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16. Full Text Selective Targeting of a Novel Epsin–VEGFR2 Interaction Promotes VEGF-Mediated Angiogenesis
by Rahman, H.N Ashiqur and Wu, Hao and Dong, Yunzhou and Pasula, Satish and Wen, Aiyun and Sun, Ye and Brophy, Megan L and Tessneer, Kandice L and Cai, Xiaofeng and McManus, John and Chang, Baojun and Kwak, Sukyoung and Rahman, Negar S and Xu, Wenjia and Fernandes, Conrad and Mcdaniel, John Michael and Xia, Lijun and Smith, Lois and Srinivasan, R Sathish and Chen, Hong
Circulation Research, ISSN 0009-7330, 03/2016, Volume 118, Issue 6, pp. 957 - 969
RATIONALE:We previously reported that vascular endothelial growth factor (VEGF)-induced binding of VEGF receptor 2 (VEGFR2) to epsins 1 and 2 triggers VEGFR2... 
VEGFR2 protein mouse | ubiquitination | neovascularization physiologic | epsin | ubiquitin | CARDIAC & CARDIOVASCULAR SYSTEMS | neovascularization | physiologic | TRAFFICKING | MECHANISMS | VEGFR2 protein | mouse | PERIPHERAL VASCULAR DISEASE | EPSIN 1 | RECEPTORS | PROTEINS | HEMATOLOGY | TUMOR-GROWTH | BINDING | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Human Umbilical Vein Endothelial Cells | Amino Acid Sequence | Protein Structure, Secondary | Humans | Mice, Inbred C57BL | Adaptor Proteins, Vesicular Transport - genetics | Molecular Sequence Data | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Mice, Transgenic | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Adaptor Proteins, Vesicular Transport - metabolism | Mice, Knockout | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor A - chemistry | Neovascularization, Physiologic - physiology | Vascular Endothelial Growth Factor Receptor-2 - chemistry | Animals | MCF-7 Cells | HEK293 Cells | Adaptor Proteins, Vesicular Transport - chemistry | Mice | Drug Delivery Systems - trends | Protein Binding - physiology | Index Medicus | VEGFR2 | UIM | Epsin | angiogenesis
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17. Full Text A Phase II and Biomarker Study of Cabozantinib in Patients with Advanced Cholangiocarcinoma
by Goyal, Lipika and Zheng, Hui and Yurgelun, Matthew B and Abrams, Thomas A and Allen, Jill N and Cleary, James M and Knowles, Michelle and Regan, Eileen and Reardon, Amanda and Khachatryan, Anna and Jain, Rakesh K and Nardi, Valentina and Borger, Darrell R and Duda, Dan G and Zhu, Andrew X
Cancer, ISSN 0008-543X, 6/2017, Volume 123, Issue 11, pp. 1979 - 1988
VEGFR2 | phase II | soluble MET | Cholangiocarcinoma | cabozantinib
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18. Full Text Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes
by Kilpatrick, Laura E and Friedman-Ohana, Rachel and Alcobia, Diana C and Riching, Kristin and Peach, Chloe J and Wheal, Amanda J and Briddon, Stephen J and Robers, Matthew B and Zimmerman, Kris and Machleidt, Thomas and Wood, Keith V and Woolard, Jeanette and Hill, Stephen J
Biochemical Pharmacology, ISSN 0006-2952, 07/2017, Volume 136, pp. 62 - 75
Vascular endothelial growth factor (VEGF) is an important mediator of angiogenesis. Here we have used a novel stoichiometric protein-labeling method to... 
VEGFR2 | BRET | Ligand binding | Receptor tyrosine kinase inhibitors | VEGF | Index Medicus
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19. Full Text VEGFR2-specific FnCAR effectively redirects the cytotoxic activity of T cells and YT NK cells
by Kulemzin, Sergey V and Gorchakov, Andrey A and Chikaev, Anton N and Kuznetsova, Valeriya V and Volkova, Olga Y and Matvienko, Daria A and Petukhov, Alexey V and Zaritskey, Andrey Y and Taranin, Alexandr V
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 10, pp. 9021 - 9029
T and NK cells armed with chimeric antigen receptors (CAR) are promising tools for the specific elimination of cancer cells. In most CAR designs implemented to... 
Chimeric antigen receptors | VEGFR2 | FnCAR | NK cells | Fn3
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20. Full Text Synthesis of Novel c(AmpRGD) Sunitinib Dual Conjugates as Molecular Tools Targeting the alpha(v)beta(3) Integrin/VEGFR2 Couple and Impairing Tumor-Associated Angiogenesis
by Sartori, A and Portioli, E and Battistini, L and Calorini, L and Pupi, A and Vacondio, F and Arosio, D and Bianchini, F and Zanardi, F
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 01/2017, Volume 60, Issue 1, pp. 248 - 262
On the basis of a previously discovered anti-alpha(v)beta(3) integrin peptidomimetic (c(AmpRGD)) and the clinically approved antiangiogenic kinase inhibitor... 
VEGFR2 | RGD-PEPTIDE | CHEMISTRY, MEDICINAL | THERAPY | DRUG DISCOVERY | GROWTH | BIOLOGICAL EVALUATION | OPEN-LABEL | INHIBITORS | CANCER | CILENGITIDE
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