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Organic Letters, ISSN 1523-7060, 03/2017, Volume 19, Issue 5, pp. 1000 - 1003
Bioassay-guided metabolomic analyses led to the characterization of four new 20-membered glycosylated polyketide macrolactams, macrotermycins A–D, from a... 
CHEMISTRY, ORGANIC | STREPTOMYCES SP | VICENISTATIN | INCEDNINE | DISCOVERY | SYMBIONTS | Actinomycetales | Anti-Bacterial Agents | Glycosylation | Molecular Structure | Animals | Isoptera
Journal Article
Current Opinion in Chemical Biology, ISSN 1367-5931, 12/2016, Volume 35, pp. 58 - 64
•Biosynthetic pathways of β-amino acid-containing macrolactams are reviewed.•Functional and structural studies uncover the β-amino acid incorporation... 
ACYL CARRIER PROTEIN | ENZYME | BIOPHYSICS | GENE-CLUSTER | CRYSTAL-STRUCTURE | SIDE-CHAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | STARTER UNIT | ADENYLATION DOMAINS | IDENTIFICATION | ANTIBIOTIC VICENISTATIN | REVEALS | Amino Acids - chemistry | Amino Acid Sequence | Amino Acids - metabolism | Lactams - metabolism | Polyketides - metabolism
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2005, Volume 46, Issue 37, pp. 6187 - 6190
New aglycon switch approach using glycosyltransferase VinC was explored to create unnatural glycosides from natural glycoside in one-pot reaction. New aglycon... 
Enzymatic synthesis | Antibiotic | Glycoside | Glycosyltransferase | Vicenistatin | antibiotic | CHEMISTRY, ORGANIC | vicenistatin | enzymatic synthesis | glycoside | glycosyltransferase | Glycosides | Enzymes
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2016, Volume 26, Issue 23, pp. 5770 - 5772
[Display omitted] Extracellular administration of water-soluble and membrane-permeant analogs of phosphatidylinositol phosphates (PIPs) is a useful strategy... 
Phosphatidylinositol 3,5-bisphosphates | Dioctanoyl analog | Acetoxymethyl ester | Chemical synthesis | CELLS | CHEMISTRY, MEDICINAL | PHOSPHORYLATION | MEMBRANE-PERMEANT ESTERS | CHEMISTRY, ORGANIC | 3,5-BISPHOSPHATE | VICENISTATIN | Phospholipids
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 10/2010, Volume 8, Issue 20, pp. 4682 - 4689
A Streptomyces sp. isolated from a shallow water sediment sample collected off Heron Island, Australia, afforded three new polyketide macrolactams, heronamides... 
CHEMISTRY, ORGANIC | MACROCYCLIC LACTAM | ACTINOMYCETE | VICENISTATIN | Streptomyces - metabolism | Lactams, Macrocyclic - chemistry | Macrolides - chemistry | Lactams, Macrocyclic - metabolism | Streptomyces - chemistry | Chromatography, High Pressure Liquid | Australia
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 03/2014, Volume 2014, Issue 7, pp. 1376 - 1380
The total synthesis of the proposed structure of heronamide C was accomplished through a Sato–Micalizio reductive alkyne–alkyne coupling strategy and... 
Cross‐coup­ling | Macrocycles | Natural products | Total synthesis | Alkynes | Cross-coupling | CHEMISTRY, ORGANIC | ALDEHYDES | STANNYLCUPRATION | MACROCYCLIC LACTAM | MACROLACTAM | BE-14106 | STEREOSELECTIVE-SYNTHESIS | VICENISTATIN | Chemotherapy | Synthesis | Organic compounds | Cancer
Journal Article
Synlett, ISSN 0936-5214, 10/2010, Volume 2010, Issue 17, pp. 2589 - 2592
Abstract A highly convergent total synthesis of macrocyclic lactam glycoside vicenistatin is described. Key features of the synthesis include rapid assembly of... 
letter | vicenistatin | macrolactam | total synthesis | vicenisamine | SECONDARY ALCOHOLS | SYSTEM | CHEMISTRY, ORGANIC | ALDEHYDES | EFFICIENT | CATALYSTS
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 07/2011, Volume 21, Issue 13, pp. 3905 - 3908
A new rare 20-membered macrocyclic lactam incorporating a diene conjugated olefin, designated sannastatin (1), together with the known structurally related... 
Sannastatin | Toxic activity | Streptomyces sannanensis | 20-Membered macrocyclic lactam | Ailuropoda melanoleuca | MACROCYCLIC LACTAM | CHEMISTRY, MEDICINAL | STRUCTURAL ELUCIDATION | CHEMISTRY, ORGANIC | SANNAMYCIN | VICENISTATIN | AMINOGLYCOSIDE ANTIBIOTICS
Journal Article
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 05/2016, Volume 80, Issue 5, pp. 902 - 910
Journal Article
Tetrahedron, ISSN 0040-4020, 2008, Volume 64, Issue 28, pp. 6651 - 6656
Incednine was isolated from Streptomyces sp. ML694-90F3 as an inhibitor of anti-apoptotic function of Bcl-2/Bcl-xL oncoproteins. The structure of incednine is... 
GENE-CLUSTER | CLONING | ENZYMES | STARTER UNIT | CHEMISTRY, ORGANIC | 2,3-AMINOMUTASE | LYSINE 5,6-AMINOMUTASE | ANTIBIOTIC VICENISTATIN
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2006, Volume 47, Issue 10, pp. 1529 - 1532
The excited thioesterase (TE) domain from the vicenistatin polyketide synthase (PKS) efficiently catalyzed the macrolactam formation of the N-acetylcysteamine... 
Polyketide synthase | Macrolactam formation | Thioesterase | Vicenistatin | CYCLASE | polyketide synthase | NONRIBOSOMAL PEPTIDE SYNTHETASE | SPECIFICITY | STARTER UNIT | CHEMISTRY, ORGANIC | ANTIBIOTIC VICENISTATIN | macrolactam formation | BIOSYNTHETIC GENE-CLUSTER | CHANNEL | thioesterase | vicenistatin | CYCLIZATION | Polyketides | Esterases
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 05/2005, Volume 127, Issue 17, pp. 6148 - 6149
Journal Article
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