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A heminested polymerase chain reaction for the detection of Brazilian rabies isolates from vampire bats and herbivores, 12/2002
A heminested-PCR (hn-PCR) using primers to the nucleoprotein-coding gene in a nested set was evaluated in the detection of Brazilian strains of rabies virus... 
rabies virus, polymerase chain reaction, detection of viral RNA, rabies diagnosis, Brazil
Journal
Antiviral Research, ISSN 0166-3542, 09/2019, Volume 169, p. 104547
Zika virus (ZIKV) infection can cause neonatal microcephaly and neurological disorders. Currently, there is no designated drug for treating ZIKV infection and... 
Viral RNA release | Zika virus | Autophagy | Chloroquine
Journal Article
Cell, ISSN 0092-8674, 2/2018, Volume 172, Issue 5, pp. 966 - 978.e12
Ebola virus nucleoprotein (eNP) assembles into higher-ordered structures that form the viral nucleocapsid (NC) and serve as the scaffold for viral RNA... 
Ebola virus | nucleocapsid | nucleoprotein | cryoEM | viral RNA synthesis
Journal Article
11/2012
The satellite RNA of Lucerne Transient Streak Virus (LTSV) is a 322-nucleotide, single-stranded circular RNA that has a rod-like structure very similar to that... 
Lucerne Transient Streak Virus | Satellite RNA | Viral RNA-dependent RNA polymerase | 0720 | 0410 | Viroid | 0307
Dissertation
Journal of Hepatology, ISSN 0168-8278, 01/2018, Volume 68, Issue 1, pp. 16 - 24
In diagnostics, serum hepatitis B virus (HBV)-RNA levels are valuable when the HBV-DNA load in circulation is effectively suppressed by nucleos(t)ide analogue... 
Viral RNA | Nucleos(t)ide analogues | Histopathology | Chronic hepatitis B | Viral replication
Journal Article
Molecular Therapy - Nucleic Acids, ISSN 2162-2531, 06/2019, Volume 16, pp. 105 - 117
The important role of insulin-like growth factor-1 receptor (IGF-1R) in tumorigenesis has been well established. The classical model involves IGF-1R binding to... 
RIG-I | viral RNA sensors | IGF-1R | mitochondrial apoptosis | MDA5
Journal Article
GASTROENTEROLOGY, ISSN 0016-5085, 04/2007, Volume 132, Issue 4, pp. 1270 - 1278
Background & Aims: SCH 503034 is a novel and potent oral hepatitis C virus (HCV) protease inhibitor. In this phase lb study, we assessed safety parameters and... 
PROTEASE INHIBITOR | VIRAL-RNA | REPLICON CELLS | PEGINTERFERON ALPHA-2B | NS3 PROTEASE | ANTIVIRAL EFFICACY | RANDOMIZED-TRIAL | SERINE-PROTEASE | RIBAVIRIN | GASTROENTEROLOGY & HEPATOLOGY | ADAPTER PROTEIN
Journal Article
Virology, ISSN 0042-6822, 9/2015, Volume 483, pp. 149 - 162
The 356 nt noncoding satellite RNA C (satC) of Turnip crinkle virus (TCV) is composed of 5′ sequences from a second TCV satRNA (satD) and 3′ sequences derived... 
viral RNA evolution | satellite RNA | Turnip crinkle virus | SELEX
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 08/2005, Volume 102, Issue 33, pp. 11928 - 11933
ARGONAUTE (AGO) RNA-binding proteins are involved in RNA silencing. They bind to short interfering RNAs (siRNAs) and microRNAs [miRNAs) through a conserved PAZ... 
BINDING-PROTEIN HYL1 | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | PLANT DEVELOPMENT | DISTINCT ROLES | silencing | LEAF DEVELOPMENT | posttranscriptional regulation | PAZ DOMAIN | MESSENGER-RNAS | TRANS-ACTING SIRNAS | C-ELEGANS | viral RNA | EFFECTOR COMPLEXES | ribonuclease
Journal Article
Nature Reviews Microbiology, ISSN 1740-1526, 05/2008, Volume 6, Issue 5, pp. 363 - 374
Journal Article
PLoS Pathogens, ISSN 1553-7366, 12/2012, Volume 8, Issue 12, p. e1003056
Journal Article
Current Opinion in Infectious Diseases, ISSN 0951-7375, 04/2019, Volume 32, Issue 2, pp. 176 - 186
PURPOSE OF REVIEWWe review antivirals inhibiting subunits of the influenza polymerase complex that are advancing in clinical development. RECENT... 
influenza | INFECTIOUS DISEASES | INFECTIONS | ribavirin | VIRAL-RNA POLYMERASE | SUSCEPTIBILITY | baloxavir | OSELTAMIVIR | pimodivir | ENDONUCLEASE | T-705 | THERAPIES | favipiravir | Special
Journal Article
Journal of virology, ISSN 0022-538X, 02/2019, Volume 93, Issue 4
The genome of influenza A virus is organized into eight ribonucleoproteins, each composed of a distinct RNA segment bound by the viral polymerase and... 
influenza | vRNPs | nucleoprotein | complexity | packaging | VIRAL-RNA | SIGNALS | A VIRUS | CONSERVATION | VIROLOGY | SEGMENTS | REGIONS | BIOLOGY | GENERATION | RESIDUES | BINDING
Journal Article
2013, Current Topics in Microbiology and Immunology, Volume 369, 32
Genome replication is a crucial step in the life cycle of any virus. HCV is a positive strand RNA virus and requires a set of nonstructural proteins (NS3, 4A,... 
INFECTIOUS DISEASES | 4-KINASE III ALPHA | VIRAL-RNA | NONSTRUCTURAL PROTEIN 5A | DE-NOVO INITIATION | CIS-ACTING REPLICATION | SECONDARY STRUCTURE | POLYMERASE ACTIVITY | IMMUNOLOGY | SERINE-TYPE PROTEINASE | CORE PROTEIN | MEMBRANE ASSOCIATION
Book Chapter
JOURNAL OF VIROLOGY, ISSN 0022-538X, 08/2019, Volume 93, Issue 15
Myxovirus resistance 1 (Mx1) is an interferon-induced gene that encodes a GTPase that plays an important role in the defense of mammalian cells against... 
ORTHOMYXOVIRIDAE | myeloid cells | VIRAL-RNA | Mx1 | MATRIX PROTEIN | POLYMERASE | Thogoto virus | bone marrow chimeras | VIROLOGY | INFLUENZA-A VIRUS | RESISTANCE | MICE | TICK-BORNE | OLIGOMERIZATION | GENE-PRODUCT
Journal Article