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Journal Article
Nucleic Acids Research, ISSN 0305-1048, 06/2003, Volume 31, Issue 12, pp. 3185 - 3193
Locked nucleic acids (LNAs) and double-stranded small interfering RNAs (siRNAs) are rather new promising antisense molecules for cell culture and in vivo... 
CAPSAICIN RECEPTOR | OLIGODEOXYNUCLEOTIDES | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | GENE-EXPRESSION | IMPROVEMENT | GROWTH-FACTOR | CHEMICAL-MODIFICATIONS | LNA | OLIGONUCLEOTIDES
Journal Article
Journal Article
Journal Article
by Cong, XL and Li, B and Yang, RC and Feng, SZ and Chen, SJ and Han, ZC
LEUKEMIA, ISSN 0887-6924, 09/2005, Volume 19, Issue 9, pp. 1517 - 1524
An antisense strategy by targeting both bcr3/abl2 and VEGF was designed to suppress the growth of Philadephia(1) leukemia cells in vitro and in vivo in mice.... 
CHRONIC MYELOGENOUS LEUKEMIA | antisense oligodeoxyribonucleotides | MECHANISM | ANGIOGENESIS | VEGF | BCR-ABL | BLAST CRISIS | apoptosis | gene therapy | bcr3/abI2 | CHRONIC MYELOID-LEUKEMIA | ONCOLOGY | IN-VIVO | TYROSINE KINASE INHIBITOR | STI-571 | HEMATOLOGY
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 12/2001, Volume 134, Issue 8, pp. 1731 - 1741
Journal Article
BRAIN RESEARCH, ISSN 0006-8993, 04/2001, Volume 898, Issue 1, pp. 113 - 121
The sigma, (sigma (1)) receptor cDNA was recently cloned in several animal species, including the mouse. In order to firmly establish the implication of sigma... 
INDUCED NEURONAL ACTIVATION | BEHAVIORAL EVIDENCE | MEDIATED BEHAVIOR | OLIGODEOXYNUCLEOTIDE ANTISENSE | MK-801-INDUCED IMPAIRMENT | spontaneous alternation | LEARNING IMPAIRMENT | dizocilpine | COGNITIVE ENHANCER | NEUROSCIENCES | passive avoidance | learning and memory | MICE | sigma (sigma) receptor | RAT-BRAIN | in vivo antisense strategy | scopolamine | MODULATION
Journal Article
CANCER GENE THERAPY, ISSN 0929-1903, 04/2003, Volume 10, Issue 4, pp. 278 - 286
Thymidylate synthase (TS) catalyzes de novo production of thymidylate for DNA synthesis and cell proliferation. As such, TS has been a target of antitumor... 
MEDICINE, RESEARCH & EXPERIMENTAL | MESSENGER-RNA TRANSLATION | combination treatment | CANCER CELLS | antisense oligodeoxynucteotide | PROMISE | thymidylate synthase | novel therapy | INHIBITION | THERAPY | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | cancer chemotherapy | IN-VIVO | GENETICS & HEREDITY | MDM2 | MICE
Journal Article
Advances in Polymer Science, ISSN 0065-3195, 2012, Volume 249, pp. 1 - 47
In this chapter, we introduce our recent work on the development of new antisense strategies in RNA synthetic technology and RNA drug discovery. In the first... 
Artificial mRNA | Double short hairpin RNA | RNA synthesis | Stereospecific modification | 2-Cyanoethoxymethyl | POLYMER SCIENCE | ESCHERICHIA-COLI | STEREOCHEMICAL COURSE | NUCLEIC-ACID ANALOGS | LIPOSOME COMPLEX | MESSENGER-RNA | PROTECTING GROUP | IN-VIVO | BIOLOGICAL-ACTIVITY | THERAPEUTIC AGENTS | STEREOCONTROLLED SYNTHESIS
Conference Proceeding
CURRENT NEUROPHARMACOLOGY, ISSN 1570-159X, 12/2008, Volume 6, Issue 4, pp. 344 - 366
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/1999, Volume 274, Issue 37, pp. 26105 - 26112
Journal Article