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Journal Article
Journal Article
Cytokine and Growth Factor Reviews, ISSN 1359-6101, 2015, Volume 26, Issue 6, pp. 673 - 685
Abstract Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most deaths in westernized societies with numbers increasing at a... 
Advanced Basic Science | Therapeutic avenues | Inflammation | Cytokines | Chemokines | Atherosclerosis | Atherosclerosis - immunology | Cytokines - metabolism | Atherosclerosis - physiopathology | Humans | Endothelium, Vascular - physiopathology | Extracellular Matrix - metabolism | Inflammation - immunology | Lipoproteins - blood | Molecular Targeted Therapy | Extracellular Matrix - chemistry | Macrophages - enzymology | Animals | Atherosclerosis - therapy | Muscle, Smooth, Vascular - chemistry | Myocardial Infarction - physiopathology | Chemokines - metabolism | Mice | Matrix Metalloproteinases - metabolism | Macrophages - immunology | Chemokines - immunology | Cytokines - immunology | Endothelium, Vascular - immunology | Inflammation - physiopathology | Development and progression | Blood lipids | Health aspects | GM-CSF, granulocyte macrophage colony-stimulating factor | ECM, extracellular matrix | RCT, reverse cholesterol transport | ICAM-1, intercellular adhesion molecule-1 | LDLr, low-density lipoprotein receptor | PECAM-1, platelet endothelial cell adhesion molecule-1 | ABC, ATP-binding cassette | IL-1RA, IL-1 receptor antagonist | ADRP, adipocyte differentiation related protein | SREBP, sterol response element binding protein | wt, wild type | G-CSF, granulocyte colony-stimulating factor | PAI, plasminogen activator inhibitor | CSF, colony-stimulating factor | PRR, pattern recognition receptor | TIMP, tissue inhibitor of metalloproteinases | NPC, Niemann-Pick disease, type C | TNF, tumor necrosis factor | TL1A, TNF-like protein 1A | NLR, NOD-like receptor | SMCs, smooth muscle cells | CR, chemokine receptor | Tregs, regulatory T cells | Survey | GDF-15, growth differentiation factor-15 | NK, natural killer | TNFSF12, TNF superfamily member 12 | IL, interleukin | NLRP3, NLR family, pyrin domain containing 3 | mmLDL, minimally modified LDL | LIGHT, homologous to lymphotoxin, exhibits inducible expression, and competes with HSV glycoprotein D for herpes virus entry mediator, a receptor expressed by T lymphocytes | TF, tissue factor | Th, T-helper | MMP, matrix metalloproteinase | OxLDL, oxidized LDL | CVD, cardiovascular disease | TLR, Toll-like receptor | DCs, dendritic cells | IL-18BP, IL-18 binding protein | miRNA, micro RNA | CANTOS, Canakinumab Anti-inflammatory Thrombosis Outcomes Study | TRAIL, TNF-related apoptosis-inducing ligand | ACAT-1, acyl-CoA acyl transferase-1 | ECs, endothelial cells | TWEAK, TNF-related weak inducer of apoptosis | TGF, transforming growth factor | LFA1, lymphocyte function-associated antigen 1 | ROS, reactive oxygen species | CIRT, Cardiovascular Inflammation Reduction Trial | LDL, low-density lipoprotein | IFN, interferon | MIF, macrophage migration inhibitory factor | SR, scavenger receptor | eNOS, endothelial nitric oxide synthase | STAT1, signal transducer and activator of transcription-1 | Fn14, fibroblast growth factor-inducible 14 | VCAM-1, vascular cell adhesion molecule-1 | LXR, liver X receptors | MHC, major histocompatibility complex | CCR2, CC-chemokine receptor-2 | NOD, nucleotide-binding oligomerization domain | VLA4, very late antigen 4 | BMT, bone marrow transplantation | SR-PSOX, SR that binds phosphatidyl serine and oxidized lipoprotein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | Apo, apolipoprotein | M-CSF, macrophage-colony stimulating factor | ER, endoplasmic reticulum
Journal Article
Journal Article
Journal Article
Immunological Investigations, ISSN 0882-0139, 10/2015, Volume 44, Issue 7, pp. 694 - 712
Background and Purpose: Some functional limitations and economic burden of therapeutic antibodies indicated that introducing of alternative therapeutic... 
EAE | neuro-inflammation | VLA4 | BIO-1211 | multiple sclerosis | CORTICAL DEMYELINATION | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DIFFERENT SUBTYPES | C57BL/6 MICE | NATALIZUMAB | IMMUNOLOGY | B-CELLS | IN-VIVO | ANIMAL-MODEL | IRANIAN PATIENTS | T-CELLS | Leukocyte Common Antigens - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Cerebral Cortex - pathology | Encephalomyelitis, Autoimmune, Experimental - immunology | Male | Monocytes - metabolism | Thiazoles - administration & dosage | Monocytes - immunology | RNA, Messenger - metabolism | Cerebral Cortex - metabolism | Cell Movement - immunology | Leukocytes - immunology | Inflammation Mediators - metabolism | Encephalomyelitis, Autoimmune, Experimental - genetics | Cytokines - genetics | Oligopeptides - chemistry | Disease Models, Animal | Multiple Sclerosis - metabolism | Permeability - drug effects | Encephalomyelitis, Autoimmune, Experimental - pathology | Cytokines - metabolism | Encephalomyelitis, Autoimmune, Experimental - drug therapy | RNA, Messenger - genetics | Multiple Sclerosis - genetics | Blood-Brain Barrier - drug effects | Disease Progression | Blood-Brain Barrier - metabolism | Gene Expression Regulation - drug effects | Animals | Cerebral Cortex - immunology | Integrin alpha4beta1 - antagonists & inhibitors | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Mice | Oligopeptides - administration & dosage | Thiazoles - pharmacology | CD11b Antigen - metabolism | Oligopeptides - pharmacology | Leukocytes - metabolism | Multiple Sclerosis - drug therapy
Journal Article
International Archives of Allergy and Immunology, ISSN 1018-2438, 01/2000, Volume 121, Issue 1, pp. 25 - 33
Background: The α4 integrin, as α4β1 (VLA-4) or α4β7, is critical for T cell migration and proliferation, although its functional modulation remains poorly... 
Original Paper | VLA4 | CD45RO | Integrin, a | T cells | Adhesion | Allergen
Journal Article