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JOURNAL OF GENERAL VIROLOGY, ISSN 0022-1317, 07/2019, Volume 100, Issue 7, pp. 1099 - 1111
Ebola virus (EBOV) VP40 is a major driving force of nascent virion production and a negative regulator of genome replication/transcription. Here, we showed... 
intramolecular interaction | SYSTEM | MOTIFS | FINGER-Z-PROTEIN | TSG101 | UBIQUITIN LIGASE | RNA REPLICATION | genome replication | PLASMA-MEMBRANE | Ebola virus | VIROLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | assembly | OLIGOMERIZATION | MATRIX PROTEIN VP40 | DOMAINS | VP40
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 9776 - 11
The Ebola filovirus causes severe hemorrhagic fever with a high fatality rate in humans. The primary structural matrix protein VP40 displays... 
MOLECULAR-DYNAMICS | PROTEIN VP40 | NUCLEOPROTEIN | MULTIDISCIPLINARY SCIENCES | Epidemics | Antiviral agents | Hemorrhagic fever | VP40 protein | Hexamers | Amino acids | Drug development | Hemorrhage | Virus-like particles | Ebola virus | Proteins | Matrix protein | Budding
Journal Article
Frontiers in Microbiology, ISSN 1664-302X, 11/2016, Volume 7, p. 1765
Ebola virus (EBOV) is an enveloped, ssRNA virus from the family Filoviridae capable of causing severe hemorrhagic fever with up to 80-90% mortality rates. The... 
Ebola virus | MicroRNA | EBOV | ESCRT | VLP | Exosomes | VP40 | Apoptosis | RNA | apoptosis | MICROBIOLOGY | PATHOGENESIS | INHIBITION | EXTRACELLULAR VESICLES | exosomes | IN-VIVO | IMMUNODEFICIENCY-VIRUS TYPE-1 | microRNA | INFECTION | VIRAL MIRNAS | MATRIX PROTEIN VP40 | Immune response | Observations | Health aspects | BASIC BIOLOGICAL SCIENCES
Journal Article
Frontiers in Microbiology, ISSN 1664-302X, 2014, Volume 5, p. 300
Lipid-enveloped viruses contain a lipid bilayer coat that protects their genome and helps to facilitate entry into the host cell. Filoviruses are... 
Phosphoinositides | Membrane binding | Plasma membrane | Filovirus | Ebola | Phosphatidylserine | VP40 | plasma membrane | CRYSTAL-STRUCTURE | MICROBIOLOGY | filovirus | PLASMA-MEMBRANE | phosphoinositides,VP40 | C2 DOMAINS | phosphatidylserine | VIRAL-EGRESS | VIRUS MATRIX PROTEIN | INFECTION | VESICULAR STOMATITIS-VIRUS | OLIGOMERIZATION | ASSOCIATION | membrane binding | phosphoinositides
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2017, Volume 377, Issue 15, pp. 1428 - 1437
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2017, Volume 7
We present the structure of the surface Ebola virus (EBOV) trimeric glycoprotein (GP) spike at 11 angstrom resolution, in situ within the viral plasma membrane... 
ENTRY REQUIRES | VISUALIZATION | ANTIBODIES | SYSTEM | NIEMANN-PICK C1 | ORIENTATION | MULTIDISCIPLINARY SCIENCES | GP2 | MICROSCOPY | NEUTRALIZATION | VP40
Journal Article
Journal of Virology, ISSN 0022-538X, 11/2017, Volume 91, Issue 22
Journal Article
Vaccine, ISSN 0264-410X, 2017, Volume 36, Issue 22, pp. 3090 - 3100
Abstract Infections with filoviruses in humans are highly virulent, causing hemorrhagic fevers which result in up to 90% mortality. In addition to natural... 
Allergy and Immunology | VP24 | Subunit vaccine | VP40 | Recombinant subunit proteins | Zaire ebolavirus | NONHUMAN-PRIMATES | MEDICINE, RESEARCH & EXPERIMENTAL | NEUTRALIZING ANTIBODIES | DENDRITIC CELLS | PARTICLES | I INTERFERON RESPONSE | INSECT CELLS | VACCINE | IMMUNOLOGY | MARBURG VIRUSES | HEMORRHAGIC-FEVER | STIMULATING ACTIVITY | Ebolavirus | Adjuvants, Immunologic - administration & dosage | Hemorrhagic Fever, Ebola - prevention & control | Viral Proteins - immunology | Vaccines, Subunit - immunology | Vaccines, Synthetic - immunology | Antibodies, Viral - blood | Animals | Immunity, Humoral | Ebola Vaccines - immunology | Female | Viral Envelope Proteins - immunology | Hemorrhagic Fever, Ebola - immunology | Mice | Mice, Inbred BALB C | Viral Matrix Proteins - immunology | Immunity, Cellular | Antibodies, Neutralizing - blood | Medical research | Medical colleges | Hemorrhagic fever | Immune response | Mortality | Disease susceptibility | Recombinant proteins | Homeopathy | Materia medica and therapeutics | Ebola virus | Analysis | Therapeutics | Medicine, Experimental | Health aspects | VP24 protein | Adaptive systems | Disease | Pathogenesis | VP40 protein | Viral diseases | Clinical trials | Viruses | Infections | Vaccines | Hemorrhage | Proteins | Replicating | Lymphocytes | Recombinant | Immune system | Thrombocytopenia | Glycoprotein | Bioterrorism | Immune response (humoral) | Immunogenicity | Insects | Lymphopenia | Viral infections
Journal Article