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Molecular & Biochemical Parasitology, ISSN 0166-6851, 09/2016, Volume 209, Issue 1-2, pp. 18 - 25
Journal Article
Insect Biochemistry and Molecular Biology, ISSN 0965-1748, 07/2015, Volume 62, pp. 211 - 225
In eukaryotic cells, regulated vesicular trafficking is critical for directing protein transport and for recycling and degradation of membrane lipids and... 
VPS | GARP | ESCRT | Retromer | VPS-C | PI3K-III
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 1/2002, Volume 156, Issue 2, pp. 271 - 285
Exocytic vesicles that accumulate in a temperature-sensitive sec6 mutant at a restrictive temperature can be separated into at least two populations with... 
Yeasts | Fractionation | Epithelial cells | Freight transport | Cell membranes | Freight | Cells | Vacuoles | Endosomes | Membrane proteins | VPS | Protein sorting | TGN | Yeast secretion | Endosome | BIOSYNTHETIC TRANSPORT | ENDOCYTIC PATHWAY | PREVACUOLAR COMPARTMENT | CELL-SURFACE | protein sorting | GTP-BINDING PROTEINS | yeast secretion | SACCHAROMYCES-CEREVISIAE | PLASMA-MEMBRANE | SECRETORY PATHWAY | CELL BIOLOGY | endosome | TRANS-GOLGI NETWORK | MANNOSE 6-PHOSPHATE RECEPTOR | Temperature | Proton-Translocating ATPases - immunology | Saccharomyces cerevisiae - genetics | Alkaline Phosphatase - metabolism | Secretory Vesicles - metabolism | Exocytosis | Clathrin-Coated Vesicles - metabolism | Proton-Translocating ATPases - metabolism | Saccharomyces cerevisiae - metabolism | Cathepsin A | Vesicular Transport Proteins | Saccharomyces cerevisiae Proteins - immunology | Centrifugation, Density Gradient | Receptors, Cell Surface - metabolism | Fungal Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Mutation - genetics | Blotting, Western | Protein Transport | Saccharomyces cerevisiae - cytology | Carrier Proteins - genetics | Carrier Proteins - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Vacuoles - metabolism | Carboxypeptidases - metabolism | Golgi Apparatus - metabolism | Glycoside Hydrolases - metabolism | Fungal Proteins - metabolism | Receptors, Cell Surface - genetics | beta-Fructofuranosidase | Physiological aspects | Clathrin | Yeast | Research | Biological transport | vps1 gene | vps10^D gene | pep12 gene | ap16^D gene | vps41^D gene | protein sorting; TGN; endosome; VPS; yeast secretion
Journal Article
Frontiers in neuroscience, ISSN 1662-4548, 2016, Volume 10, p. 532
Mammalian retromers play a critical role in protein trans-membrane sorting from endosome to the trans-Golgi network (TGN). Recently, retromer alterations have... 
Journal Article
Autophagy, ISSN 1554-8627, 01/2010, Volume 6, Issue 1, pp. 86 - 99
Although it has been established that Atg6/Beclin 1, the phosphatidylinositol 3-kinase (PI3K) Vps34, and associated proteins have direct or indirect roles in... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Phagophore | Uvrag | VPS pathway | PI3K | Pexophagy | Isolation membrane | Vps34 | Atg6 | Autophagy | autophagy | BECLIN 1 | PEROXISOMES | MEMBRANE-PROTEIN | isolation membrane | SACCHAROMYCES-CEREVISIAE | SELECTIVE AUTOPHAGY | CELL BIOLOGY | YEAST | pexophagy | TARGETING PATHWAY | CONSERVED DOMAIN | phagophore | MOLECULAR-MECHANISMS
Journal Article
Frontiers in Neuroscience, 11/2016, Volume 10
Mammalian retromers play a critical role in protein trans-membrane sorting from endosome to the trans-Golgi network (TGN). Recently, retromers have been linked... 
VPS | Protein Clearance | Neurogenetics | Genetic Parkinsonism | Autophagoproteasome
Journal Article
Biochimica et Biophysica Acta - Molecular Cell Research, ISSN 0167-4889, 2008, Volume 1783, Issue 6, p. 974
The vacuolar/endosomal network has an important but as yet undefined role in the cellular tolerance to saltstress. We hypothesized that the mechanistic basis... 
GFP | vacuolar protein sorting | phenotype | vps deletion mutant | sodium export | Biokemi och molekylärbiologi | Atom- och molekylfysik och optik | Biochemistry and Molecular Biology | Atom and Molecular Physics and Optics | yeast
Journal Article
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 02/2009, Volume 417, Issue 3, pp. 747 - 755
The mammalian Class III PI3K (phosphoinositide 3-kinase), hVps34 [mammalian Vps (vacuolar protein sorting) 34 homologue], is an important regulator of... 
Beclin-1 | Mammalian target of rapamycin (mTOR) | UV radiation resistance-associated gene (UVRAG) | Autophagy | Mammalian vacuolar protein sorting 34 (Vps34) | Vacuolar protein sorting 15 (Vps15) | COMPLEX | ACTIVATION | autophagy | 3-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | vacuolar protein sorting 15 (Vps15) | mammalian target of rapamycin (mTOR) | VPS15 PROTEIN-KINASE | TRAFFICKING | LYSOSOME-LIKE VACUOLE | beclin-1 | mammalian vacuolar protein sorting 34 (Vps34) | YEAST | LIPID KINASE | VPS34 | Cricetinae | Tumor Suppressor Proteins - metabolism | Calmodulin - metabolism | Cricetulus | Signal Transduction | Endosomal Sorting Complexes Required for Transport | Humans | Protein-Serine-Threonine Kinases - genetics | Phosphatidylinositol 3-Kinases - metabolism | Vacuolar Sorting Protein VPS15 | Apoptosis Regulatory Proteins - metabolism | Phosphatidylinositol 3-Kinases - genetics | Animals | Membrane Proteins - metabolism | Binding Sites | Protein-Serine-Threonine Kinases - metabolism | CHO Cells | MLCK, myosin light-chain kinase | hVps34, mammalian vacuolar protein sorting 34 homologue | PI3K, phosphoinositide 3-kinase | YFP, yellow fluorescent protein | Vps, vacuolar protein sorting | HEK, human embryonic kidney | CaM, calmodulin | hVps15, mammalian vacuolar protein sorting 15 homologue | TOR, target of rapamycin | S6K1, S6 kinase 1 | AM, BAPTA(acetoxymethyl ester) | mTOR, mammalian target of rapamycin | BAPTA | MEM, minimal essential medium | Bif-1, Bax-interacting factor 1 | HA, haemagglutinin | UVRAG, UV radiation resistance-associated gene | BAPTA, 1,2-bis-(o-aminophenoxy)ethane-N,N,N′,N′-tetra-acetic acid | FBS, foetal bovine serum | D-PBS, Dulbecco's PBS
Journal Article
Biochemical Journal, ISSN 0264-6021, 11/2006, Volume 399, Issue 3, pp. 361 - 372
The covalent modification of proteins by ubiquitination is a major regulatory mechanism of protein degradation and quality control, endocytosis, vesicular... 
Endocytosis | Ubiquitination | Vesicle trafficking | Ubiquitin-binding domain | Protein structure | Proteasome | proteasome | LYS48-LINKED POLYUBIQUITIN CHAIN | DAMAGE-INDUCIBLE PROTEINS | GAT DOMAIN | ubiquitin-binding domain | BIOCHEMISTRY & MOLECULAR BIOLOGY | ZINC-FINGER DOMAIN | protein structure | UBA DOMAIN | ubiquitination | STRUCTURAL BASIS | endocytosis | PROTEIN-PROTEIN INTERACTIONS | DNA-REPAIR | INTERACTING MOTIF | GGA PROTEINS | vesicle trafficking | Polyubiquitin - metabolism | Protein Structure, Tertiary | Humans | Ubiquitin - chemistry | Ubiquitin - metabolism | Models, Molecular | Structure-Activity Relationship | Protein Transport | Animals | Ubiquitin-Protein Ligase Complexes - metabolism | Protein Binding | Protein Conformation | Protein Processing, Post-Translational | Kinetics | Proteasome Endopeptidase Complex - metabolism | Polyubiquitin - chemistry | DUIM, double-sided ubiquitin-interacting motif | GAT, GGA and TOM | UEV, ubiquitin-conjugating enzyme E2 variant | GGA, Golgi-localized, gamma-ear-containing, ADP-ribosylation-factor-binding protein | TOM, target of Myb | UBP, ubiquitin-specific processing protease | Review | UBA, ubiquitin-associated | ESCRT, endosomal sorting complexes required for transport | UBM, ubiquitin-binding motif | PFU, PLAA family ubiquitin binding | GLUE, GRAM-like ubiquitin binding in EAP45 | Vps, vacuolar sorting protein | UBZ, ubiquitin-binding zinc finger | Ubc, ubiquitin-conjugating enzyme | CUE, coupling of ubiquitin conjugation to endoplasmic reticulum degradation | ZnF, zinc finger | PAZ, polyubiquitin-associated zinc binding | RIP, receptor-interacting protein | PH, pleckstrin homology | MIU, motif interacting with ubiquitin | UIM, ubiquitin-interacting motif | NZF, Npl4 zinc finger
Journal Article
FEBS Letters, ISSN 0014-5793, 11/2015, Volume 589, Issue 22, pp. 3343 - 3353
Autophagy is an intracellular degradation system that, as a basic mechanism it delivers cytoplasmic components to the lysosomes in order to maintain adequate... 
Autophagosome biogenesis | Rab GTPase | Autophagosome–lysosome fusion | Autophagy | SNAP receptor | GTP | PAS | PtdIns3P | sequestosome 1 | TRAPP | LRRK1 | mechanistic target of rapamycin | 200 kD focal adhesion kinase family-interacting protein | unc-51 like autophagy activating kinase 1 | GAS-containing autophagosome-like vacuoles | FYCO1 | guanosine diphosphate | GDP | WD-repeat-interacting phosphoinositide proteins | CMA | guanosine nucleotide exchange factor | STX | AMD | mTOR | Group A Streptococcus | LC3 | GTPase activating protein | N-ethyl-maleimide-sensitive factor | NSF | endoplasmic reticulum exit sites | chaperone-mediated autophagy | autophagy-related protein | phosphatidylinositol 3-phosphate | light chain 3 | coat protein complex II | phagophore assembly site | Huntington disease | PKA | GEF | cAMP-dependent protein kinase | transport protein particle | GAP | NS4B | soluble N-ethyl-maleimide attachment proteins | FIP200 | GAS | MVB | AMPK | HCV | PIK3C3 | ULK1 | ERES | epidermal growth factor | SQSTM1 | class III phosphatidylinositol 3 kinase | AMP-activated protein kinase | FYVE and coiled-coil domain-containing 1 | SNARE | vacuolar protein sorting | COPII | non-structural protein 4B | age-related macular degeneration of the eye | multivesicular body | VPS | leucine-rich repeat kinase 1 | recycling endosome | WIPI | EGF | guanosine triphosphate | molecular weight | SNAP | Syntaxin | phosphatidylethanolamine | ATG | GcAVs | Hepatitis C virus | DFCP1 | endoplasmic reticulum | double FYVE domain-containing protein 1 | Autophagosome-lysosome fusion | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLASMA-MEMBRANE | RAB24 GTPASE | SMALL GTPASE | NEGATIVE REGULATOR | CELL BIOLOGY | MEMBRANE-FUSION | PROMOTES AUTOPHAGY | LONGIN DOMAIN | BIOPHYSICS | MULTIVESICULAR BODIES | WIPI PROTEINS | rab GTP-Binding Proteins - metabolism | Animals | Proteins - metabolism | Biological Transport | Humans | Intracellular Space - metabolism | SNARE Proteins - metabolism | Proteins
Journal Article