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Molecular Cell, ISSN 1097-2765, 01/2016, Volume 61, Issue 1, pp. 84 - 97
Autophagy, a cellular self-eating mechanism, is important for maintaining cell survival and tissue homeostasis in various stressed conditions. Although the... 
VPS34 complex | ULK1 | autophagy | ubiquitination | Ubiquitination | Autophagy | BECLIN 1 | PHOSPHATIDYLINOSITOL 3-KINASE | PROTEIN ATG8 | BIOCHEMISTRY & MOLECULAR BIOLOGY | REGULATES AUTOPHAGY | KINASE | MAMMALIAN AUTOPHAGY | DYNAMICS | INHIBITS AUTOPHAGY | AMBRA1 | MTOR | CELL BIOLOGY | Autophagy-Related Proteins | Phosphorylation | Vesicular Transport Proteins - metabolism | Humans | Male | Intracellular Signaling Peptides and Proteins - metabolism | Muscular Atrophy - enzymology | Adaptor Proteins, Vesicular Transport - metabolism | Autophagy-Related Protein-1 Homolog | Transfection | RNA Interference | Time Factors | Proteolysis | HEK293 Cells | Cullin Proteins - metabolism | Diabetes Complications - genetics | Membrane Proteins - metabolism | Diabetes Complications - pathology | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Beclin-1 | Muscle, Skeletal - enzymology | Signal Transduction | Mice, Inbred C57BL | Muscular Atrophy - pathology | Protein-Serine-Threonine Kinases - genetics | Ubiquitin-Protein Ligases - metabolism | Class III Phosphatidylinositol 3-Kinases - metabolism | Muscular Atrophy - genetics | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Protein Transport | Cullin Proteins - genetics | Carrier Proteins - genetics | Feedback, Physiological | Animals | Carrier Proteins - metabolism | Class III Phosphatidylinositol 3-Kinases - genetics | Ubiquitin-Protein Ligases - deficiency | Diabetes Complications - enzymology | HeLa Cells | Muscle, Skeletal - pathology | Ubiquitin-Protein Ligases - genetics | Ubiquitin | Starvation | Ligases | Medical colleges | Cell death
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 12/2008, Volume 19, Issue 12, pp. 5360 - 5372
Class III phosphatidylinositol 3-kinase (PI3-kinase) regulates multiple membrane trafficking. In yeast, two distinct PI3-kinase complexes are known: complex I... 
PRE-AUTOPHAGOSOMAL STRUCTURE | LATE ENDOSOMES | MOLECULAR MACHINERY | PROTEIN-KINASE | TRANS-GOLGI NETWORK | TUMOR-SUPPRESSOR | VPS34 PTDINS 3-KINASE | SACCHAROMYCES-CEREVISIAE | SELECTIVE AUTOPHAGY | SELF-DIGESTION | CELL BIOLOGY | Autophagy-Related Proteins | Adaptor Proteins, Vesicular Transport - classification | Humans | Adaptor Proteins, Vesicular Transport - genetics | Molecular Sequence Data | rab GTP-Binding Proteins - genetics | Autophagy - physiology | Phosphatidylinositol 3-Kinases - metabolism | Phylogeny | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Adaptor Proteins, Vesicular Transport - metabolism | Recombinant Fusion Proteins - metabolism | Multiprotein Complexes - metabolism | RNA Interference | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Phagosomes - ultrastructure | Cell Membrane - metabolism | Membrane Proteins - metabolism | Androstadienes - metabolism | Beclin-1 | rab GTP-Binding Proteins - metabolism | Amino Acid Sequence | Cell Line | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Phagosomes - metabolism | Apoptosis Regulatory Proteins - metabolism | Endocytosis - physiology | Phosphatidylinositol 3-Kinases - genetics | Multiprotein Complexes - chemistry | Sequence Alignment | Animals | Recombinant Fusion Proteins - genetics | Signal Transduction - physiology | Mice
Journal Article
Autophagy, ISSN 1554-8627, 03/2016, Volume 12, Issue 3, pp. 547 - 564
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2017, Volume 65, Issue 6, pp. 1029 - 1043.e5
Journal Article
Biochemical and biophysical research communications, ISSN 0006-291X, 02/2020
Endothelial progenitor cells (EPCs) are widely accepted to be applied in ischemic diseases. However, the therapeutic potency is largely impeded because of its... 
Journal Article
MOLECULAR BIOLOGY OF THE CELL, ISSN 1059-1524, 04/2019, Volume 30, Issue 9, pp. 1098 - 1107
Autophagy is a conserved eukaryotic pathway critical for cellular adaptation to changes in nutrition levels and stress. The class III phosphatidylinositol... 
ORGANIZATION | ATG PROTEINS | UVRAG | BECLIN 1 | 3-PHOSPHATE | BIOGENESIS | ARCHITECTURE | MEMBRANE-CURVATURE | MECHANISMS | VPS34 | CELL BIOLOGY
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2014, Volume 461, Issue 2, pp. 315 - 322
Macroautophagy is a physiological cellular response to nutrient stress, which leads to the engulfment of cytosolic contents by a double-walled membrane... 
Nuclear receptor-binding factor 2 (NRBF2) | Vacuolar protein sorting 34 (Vps34) | Autophagy | Macroautophagy | Mass spectrometry | Human vacuolar protein sorting 34 (hVps34) | Vacuolar protein sorting 15 (Vps15) | human vacuolar protein sorting 34 (hVps34) | ACTIVATION | autophagy | RAB5 | 3-KINASE | macroautophagy | BIOCHEMISTRY & MOLECULAR BIOLOGY | vacuolar protein sorting 15 (Vps15) | vacuolar protein sorting 34 (Vps34) | nuclear receptor-binding factor 2 (NRBF2) | HVPS34 | PATHOGENESIS | ROLES | mass spectrometry | ULK1 | RNA, Small Interfering - genetics | Autophagy-Related Proteins | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Adaptor Proteins, Vesicular Transport - genetics | Green Fluorescent Proteins - genetics | Mitochondrial Proteins - genetics | Adaptor Proteins, Vesicular Transport - metabolism | Lysosomes - metabolism | Mitochondrial Proteins - metabolism | Tumor Suppressor Proteins - genetics | HEK293 Cells | Trans-Activators - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Autophagy - genetics | Genes, Reporter | Beclin-1 | Green Fluorescent Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Vacuolar Sorting Protein VPS15 - genetics | Signal Transduction | Membrane Proteins - genetics | Phagosomes - metabolism | Gene Expression Regulation | Class III Phosphatidylinositol 3-Kinases - metabolism | HSP70 Heat-Shock Proteins - genetics | Apoptosis Regulatory Proteins - metabolism | HSP70 Heat-Shock Proteins - metabolism | Protein Transport | Vacuolar Sorting Protein VPS15 - metabolism | Class III Phosphatidylinositol 3-Kinases - genetics | Vacuoles - metabolism | Trans-Activators - metabolism | Trans-Activators - antagonists & inhibitors | RNA, Small Interfering - metabolism
Journal Article