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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 04/2019, Volume 27, Issue 7, pp. 1292 - 1307
Bedaquiline is a new drug of the diarylquinoline class that has proven to be clinically effective against drug-resistant tuberculosis, but has a cardiac... 
HPLC, high-performance liquid chromatography | MABA, microplate alamar blue assay | M. tb, mycobacterium tuberculosis | LORA, low oxygen recovery assay | LiTMP, lithium tetramethylpiperidide | CFU, colony-forming units | TB, tuberculosis | LDA, lithium diisopropylamide | MIC90, minimum concentration for 90% inhibition of growth | hERG (human Ether-a-go-go Related Gene) | MDR, multidrug-resistant | QFVACMXSSGTRNB-UHFFFAOYSA-N | VRRHQOVTENICRT-UHFFFAOYSA-N | HPEZANWJRVQQPY-UHFFFAOYSA-N | UGUNGVBWXUEQAQ-UHFFFAOYSA-N | YJQCLWPGMHGBLU-UHFFFAOYSA-N | IKSKNYJMDKYTOW-UHFFFAOYSA-N | NBUAEURVOPSXCJ-UHFFFAOYSA-N | OYDTTXUPMJGJQF-UHFFFAOYSA-N | KLIQFVIIBDEFSR-UHFFFAOYSA-N | PTUDVOVIFTXCHK-UHFFFAOYSA-N | SNVWFSQDKYVAAG-UHFFFAOYSA-N | UXLVGNMLOBCENA-UHFFFAOYSA-N | GUWFEHMMBHOINR-UHFFFAOYSA-N | JJEGOJPMKLRSPJ-UHFFFAOYSA-N | PEJQWNBUKMHGGO-UHFFFAOYSA-N | CEKMWLSBGRPKES-UHFFFAOYSA-N | QZVLJNAOIGLPKW-UHFFFAOYSA-N | MAHMFPJJKAUVMB-UHFFFAOYSA-N | FROBLYAPPGEAGY-UHFFFAOYSA-N | XDKSYOXEWIYWFX-UHFFFAOYSA-N | LCXPUYSULUUQTQ-UHFFFAOYSA-N | VCZLKKRCINFNGE-UHFFFAOYSA-N | GQTLJYIGFBZGEF-UHFFFAOYSA-N | YCGHXWPDGDGPKQ-UHFFFAOYSA-N | GKYYBCNOEUQDTQ-UHFFFAOYSA-N | SVYKJBBFRWVRKZ-UHFFFAOYSA-N | HARUWTIOWZSVJY-UHFFFAOYSA-N | HHDDKDPLFXIPBX-UHFFFAOYSA-N | GRADMLRLWZORGX-UHFFFAOYSA-N | VDAOJOKLIXNFRY-UHFFFAOYSA-N | PDVNUOJSRPPQNZ-UHFFFAOYSA-N | ZIMZHZVDHBTFKS-UHFFFAOYSA-N | YEGWEZNQGSXHHQ-UHFFFAOYSA-N | HEUAVAYKJDRKNK-UHFFFAOYSA-N | IEDHWPCLYLYTME-UHFFFAOYSA-N | SNWMCNSZCLYXCK-UHFFFAOYSA-N | CHEMISTRY, MEDICINAL | ASSAY | MIC90, minimum concentration for 90 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | inhibition of growth | HPLC, high-performance liquid | TUBERCULOSIS DRUG BEDAQUILINE | DIARYLQUINOLINES | chromatography LDA, lithium diisopropylamide | Drug resistance in microorganisms | Tuberculosis | International cooperation | Chemical tests and reagents | Liability (Law) | Analysis | Research institutes | High performance liquid chromatography | Lithium compounds
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