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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2008, Volume 105, Issue 27, pp. 9343 - 9348
Integrin ανβ3 is found on a subset of tumor blood vessels where it is associated with angiogenesis and malignant tumor growth. We designed an ανβ3-targeted... 
Cardiovascular system | Angiogenesis | Microscopy | Renal cell carcinoma | Antineoplastics | Blood vessels | Metastasis | Tumors | Integrins | Cancer | Intravital microscopy | Liposome | Antiangiogenic | Pancreatic cancer | REGRESSION | intravital microscopy | ANGIOGENESIS | RGD PEPTIDES | antiangiogenic | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | DOXORUBICIN | ORTHOTOPIC MODEL | liposome | BREAST-CANCER | pancreatic cancer | renal cell carcinoma | ALPHA-V-BETA-3 | VX-2 RABBIT TUMORS | INTEGRIN ALPHA(V)BETA ANTAGONISTS | Endothelium - pathology | Doxorubicin - therapeutic use | Carcinoma, Renal Cell - pathology | Pancreatic Neoplasms - blood supply | Pancreatic Neoplasms - pathology | Angiogenesis Inhibitors - pharmacology | Neoplasms - blood supply | Integrin alphaVbeta3 - metabolism | Drug Delivery Systems | Neovascularization, Pathologic - pathology | Nanoparticles | Xenograft Model Antitumor Assays | Endothelium - drug effects | Animals | Neoplasm Metastasis - drug therapy | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Neoplasms - pathology | Oligopeptides - pharmacology | Doxorubicin - pharmacology | Disease Models, Animal | Doxorubicin - administration & dosage | Control | Blood-vessels | Physiological aspects | Genetic aspects | Carcinoma, Renal cell | Research | Neovascularization | Risk factors | Methods | Biological Sciences
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2009, Volume 119, Issue 9, pp. 2830 - 2842
Journal Article
RADIOLOGY, ISSN 0033-8419, 08/2013, Volume 268, Issue 2, pp. 470 - 480
Purpose: To assess the dependence of neovascular molecular magnetic resonance (MR) imaging on relaxivity (r1) of alpha(v)beta(3)-targeted paramagnetic... 
ANTIANGIOGENIC THERAPY | ANGIOGENESIS | INTEGRINS | IN-VIVO | ATHEROSCLEROSIS | INFLAMMATORY ARTHRITIS | TARGETED FUMAGILLIN NANOPARTICLES | VX-2 RABBIT TUMORS | CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CONTRAST AGENT
Journal Article
CANCER AND METASTASIS REVIEWS, ISSN 0167-7659, 12/2008, Volume 27, Issue 4, pp. 631 - 644
The integrin alpha v beta 3 plays an important role in angiogenesis and tumor metastasis. It is expressed on activated endothelial cells as well as some tumor... 
angiogenesis | alpha v beta 3 | molecular imaging | RGD | CANCER ALPHA(V)-INTEGRIN EXPRESSION | ALPHA(V)BETA EXPRESSION | CARBON NANOTUBES | QUANTUM DOTS | BREAST-CANCER | integrins | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | ANGIOGENESIS INHIBITORS | IN-VIVO | VX-2 RABBIT TUMORS
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 12/2008, Volume 22, Issue 12, pp. 4179 - 4189
Our objectives were 1) to characterize angiogenesis in the MDA-MB-435 xenograft mouse model with three-dimensional (3D) MR molecular imaging using... 
magnetic resonance imaging | INTEGRIN ALPHABETA | antiangiogenic | BIOCHEMISTRY & MOLECULAR BIOLOGY | fumagillin | ANTIBODY | molecular imaging | INHIBITOR TNP-470 | CONTRAST AGENT | CELL BIOLOGY | BREAST-CANCER | AG-013736 | ALPHA(V)BETA | IN-VIVO | BIOLOGY | cancer | VX-2 RABBIT TUMORS | PHASE-I
Journal Article
Neuroimage, ISSN 1053-8119, 2011, Volume 54, Issue 1, pp. S106 - S124
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 09/2009, Volume 23, Issue 9, pp. 2978 - 2985
The purpose of this study was to assess whether an alternative treatment approach that targets angiogenesis, delivered through ligand-targeted nano-therapy,... 
RHEUMATOID-ARTHRITIS | perfluorocarbon nanoparticles | COLLAGEN-INDUCED ARTHRITIS | angiogenesis | BIOCHEMISTRY & MOLECULAR BIOLOGY | FUMAGILLIN | CELL BIOLOGY | systemic drug delivery | TNP-470 | INTRAARTICULAR TREATMENT | BIOLOGY | MAGNETIC-RESONANCE | 1.5 TESLA | K/BxN mouse model | VX-2 RABBIT TUMORS
Journal Article
ANGIOGENESIS, ISSN 0969-6970, 01/2014, Volume 17, Issue 1, pp. 51 - 60
Angiogenesis is an important constituent of many inflammatory pulmonary diseases, which has been unappreciated until recently. Early neovascular expansion in... 
Molecular imaging | MRI | Fluorine | Lung | MACROPHAGE | PARAMAGNETIC NANOPARTICLES | MODEL | PULMONARY ISCHEMIA | CANCER | Angiogenesis | INTEGRINS | CELL-MIGRATION | PERIPHERAL VASCULAR DISEASE | VX-2 RABBIT TUMORS | EXPRESSION | Nanotechnology
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 11/2010, Volume 24, Issue 11, pp. 4262 - 4270
The primary objective of this study was to utilize MR molecular imaging to compare the 3-dimensional spatial distribution of Robo4 and alpha(V)beta(3)-integrin... 
magnetic resonance imaging | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAGIC ROUNDABOUT | RECEPTOR | neovasculature | INHIBITS TUMOR-GROWTH | CELL BIOLOGY | ULTRASOUND | INTEGRINS | CLONING | tumor | IN-VIVO | BIOLOGY | MAGNETIC-RESONANCE | integrin | VX-2 RABBIT TUMORS | EXPRESSION | roundabout
Journal Article
Journal Article