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Nature, ISSN 0028-0836, 02/2019, Volume 566, Issue 7743, pp. 259 - 263
Cytosolic DNA triggers innate immune responses through the activation of cyclic GMP-AMP synthase (cGAS) and production of the cyclic dinucleotide second... 
2ND-MESSENGER | DNA SENSOR | CELLS | CYCLIC GMP-AMP | DINUCLEOTIDE | ACTIVATION | RECOGNITION | MULTIDISCIPLINARY SCIENCES | VACCINIA VIRUS | POXVIRUSES | REVEALS | Nucleotides, Cyclic - metabolism | Virus Replication - genetics | Humans | Vaccinia virus - growth & development | Crystallography, X-Ray | Vaccinia virus - genetics | Deoxyribonucleases - metabolism | Vaccinia virus - immunology | Signal Transduction - immunology | Genes, Viral - genetics | Conserved Sequence | Female | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Vaccinia virus - enzymology | Second Messenger Systems | Deoxyribonucleases - chemistry | Cell Line | Mice, Inbred C57BL | Butterflies - enzymology | Models, Molecular | DNA, Viral - immunology | Immunity, Innate - immunology | Animals | Immune Evasion | Mice | Moths - enzymology | Baculoviridae - enzymology | Cellular signal transduction | Nucleotide sequencing | Observations | Methods | DNA sequencing | Enzymes | Nucleases | Immune response | Crystals | Interferon | DNA binding proteins | Structure | Biological response modifiers | Cyclic guanylic acid | Genes | Viruses | Homology | Intracellular signalling | Innate immunity | Infections | Activation | Genomes | Moths | Gene deletion | Baculovirus | Kinases | Immunity | Butterflies | Degradation | Proteins | Stimulators | Cyclic GMP | Deoxyribonucleic acid--DNA | Crystal structure | AMP | Mammals | Insects
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 10/2014, Volume 70, Issue 5, pp. 1367 - 1380
Journal Article
Journal of Virology, ISSN 0022-538X, 01/2011, Volume 85, Issue 1, pp. 21 - 31
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0153183
Influenza neuraminidase (NA) proteins expressed in TK- cells infected with recombinant vaccinia virus carrying NA gene of highly pathogenic avian influenza... 
A VIRUS | IMMUNITY | IMMUNIZATION | LETHAL INFLUENZA | HEMAGGLUTININ | RECOMBINANT | MULTIDISCIPLINARY SCIENCES | PANDEMIC H1N1 | INFECTION | CROSS-PROTECTION | ANTINEURAMINIDASE ANTIBODY | Influenza A Virus, H1N1 Subtype - immunology | Influenza A Virus, H5N1 Subtype - enzymology | Orthomyxoviridae Infections - prevention & control | Immune Sera | Viral Proteins - immunology | Influenza A Virus, H5N1 Subtype - genetics | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Antibodies, Viral - blood | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Madin Darby Canine Kidney Cells | Biological Assay | Female | Influenza A Virus, H1N1 Subtype - genetics | Disease Models, Animal | Enzyme-Linked Immunosorbent Assay | Glycosylation | Blotting, Western | Cross Reactions | Animals | Virus Replication | Influenza A Virus, H1N1 Subtype - enzymology | Influenza A Virus, H5N1 Subtype - immunology | Dogs | Fluorescent Antibody Technique | Antibody Formation | Mice | Mice, Inbred BALB C | Genetic Vectors | Orthomyxoviridae Infections - virology | Orthomyxoviridae Infections - immunology | Avian influenza viruses | Physiological aspects | Genetic aspects | Research | Viral proteins | Biological properties | Pandemics | Zoology | Antibodies | Homology | Viruses | Event-related potentials | Infections | Vaccines | Assaying | Avian flu | Molecular weight | Antibody response | Proteins | Reduction | Enzymatic activity | Exo-a-sialidase | Inhibition | Localization | N-glycosidase | Plaques | Recombinant | Enzymes | Immunization | Immunoglobulins | Medical technology | Animal sciences | Studies | Hospitals | Acids | Swine flu | Influenza | Replication | Genetic engineering | Cytoplasm | Viral infections
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 04/2019, Volume 74, Issue 1, pp. 19 - 31.e7
Viral infection triggers host defenses through pattern-recognition receptor-mediated cytokine production, inflammasome activation, and apoptosis of the... 
type I-interferon | cleavage | MAVS | innate immunity | IRF3 | apoptotic caspase | cGAS | apoptosis | immunologically silent | virus infection | STIMULATOR | ACTIVATION | RECOGNITION | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | INFLAMMASOME | ANTIVIRAL SIGNALING PROTEIN | NF-KAPPA-B | CELL-DEATH | CASPASE-8-MEDIATED CLEAVAGE | BETA | CELL BIOLOGY | Caspase 2 - genetics | Caspase 7 - metabolism | Sendai virus - pathogenicity | Caspase 9 - genetics | Caspase 9 - metabolism | Vaccinia virus - pathogenicity | Humans | Caspase 3 - metabolism | Male | Virus Diseases - virology | Caspase 2 - metabolism | Interferon Regulatory Factor-3 - genetics | Vaccinia virus - immunology | Caspases - metabolism | Caspase 3 - genetics | HEK293 Cells | Interferon Type I - metabolism | Female | Nucleotidyltransferases - metabolism | Virus Diseases - genetics | Virus Diseases - immunology | Signal Transduction | Caspase 7 - genetics | Caspases - genetics | Mice, Inbred C57BL | Sendai virus - immunology | THP-1 Cells | Immunity, Innate | Host-Pathogen Interactions | Virus Diseases - enzymology | Animals | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | Apoptosis | Virus diseases | Interferon | Transplantation | Biological response modifiers | Cell differentiation | Health aspects | Cyclic guanylic acid | Hematopoietic stem cells
Journal Article