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PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e64010
Lantibiotics are peptides, produced by bacteria, that contain the noncanonicalamino acid lanthionine and many of them exhibit antibacterial activities. The... 
TARGET | HERPES-SIMPLEX-VIRUS | IN-VITRO | ENTRY | MULTIDISCIPLINARY SCIENCES | GRIFFITHSIN | INFECTION | SYNERGISTIC ACTIVITY | SEXUAL TRANSMISSION | TENOFOVIR | GEL | Anti-HIV Agents - pharmacology | Leukocytes, Mononuclear - metabolism | Lactobacillus - growth & development | Simplexvirus - physiology | Bacteriocins - chemistry | Epithelial Cells - drug effects | Giant Cells - drug effects | Humans | Virus Internalization - drug effects | HIV Envelope Protein gp120 - metabolism | Leukocytes, Mononuclear - virology | Lectins, C-Type - metabolism | HIV-1 - physiology | HIV Infections - pathology | HIV-1 - isolation & purification | Lactobacillus - drug effects | Protein Binding - drug effects | Female | Vagina - pathology | Simplexvirus - drug effects | Virus Replication - drug effects | Leukocytes, Mononuclear - drug effects | Receptors, CXCR5 - metabolism | HIV-1 - drug effects | HIV Infections - virology | Receptors, Cell Surface - metabolism | Epithelial Cells - pathology | Nisin - metabolism | Cell Adhesion Molecules - metabolism | Receptors, CXCR4 - metabolism | Leukocytes, Mononuclear - pathology | Nisin - pharmacology | Epithelial Cells - microbiology | Bacteriocins - pharmacology | Drug Resistance, Viral - drug effects | Vagina - microbiology | Kinetics | CD4 Antigens - metabolism | Prevention | Technology application | Disease transmission | Peptides | T cells | HIV (Viruses) | Acyclovir | Antibacterial agents | Drugs | Toxicity | Amino acids | Viruses | Lymphocytes T | Infections | Lantibiotics | Drug resistance | Proteins | Tenofovir | Synergistic effects | Saquinavir | CD69 antigen | Receptors | Sexually transmitted diseases | Microbicides | Enfuvirtide | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Antiviral activity | Lead | CD25 antigen | Bacteria | Inhibition | Pretreatment | Heparan sulfate | Medical research | Enzymes | Cytokines | Lactobacilli | Vagina | Envelope protein | Cultures | Inflammation | Virology | CD4 antigen | DC-SIGN protein | Studies | Glycoprotein gp120 | Chemokines | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2016, Volume 374, Issue 13, pp. 1221 - 1231
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2015, Volume 372, Issue 6, pp. 509 - 518
Preventing HIV-1 infection is a high global priority. This study assessed prevention strategies in young women in South Africa, Uganda, and Zimbabwe using oral... 
TRIALS | MEDICINE, GENERAL & INTERNAL | TRANSMISSION | ANTIRETROVIRAL PROPHYLAXIS | MICROBICIDE | PREVENTION | ADHERENCE | GEL | HIV Infections - prevention & control | Humans | Middle Aged | Drug Resistance, Viral | Administration, Intravaginal | Deoxycytidine - blood | Adenine - blood | Tenofovir | Young Adult | Adenine - adverse effects | Adult | Deoxycytidine - adverse effects | Female | Organophosphonates - blood | Surveys and Questionnaires | Anti-Retroviral Agents - blood | Drug Therapy, Combination | Emtricitabine | Adenine - analogs & derivatives | HIV Seropositivity | Administration, Oral | HIV-1 - drug effects | Deoxycytidine - administration & dosage | Anti-Retroviral Agents - adverse effects | Organophosphonates - adverse effects | Africa South of the Sahara | Adenine - administration & dosage | Pre-Exposure Prophylaxis | Organophosphonates - administration & dosage | Medication Adherence | Anti-Retroviral Agents - administration & dosage | Adolescent | HIV Infections - complications | Deoxycytidine - analogs & derivatives | Women | Care and treatment | HIV infection in women | Dosage and administration | HIV infection | Health aspects | Risk factors | Intervention | Creatinine | Antiretroviral drugs | Motivation | Human immunodeficiency virus--HIV | Prophylaxis | Vagina | Infections | Preventive medicine
Journal Article
Fertility and Sterility, ISSN 0015-0282, 2009, Volume 92, Issue 3, pp. 1025 - 1038
Objective To evaluate the effects of a tissue-selective estrogen complex (TSEC) composed of bazedoxifene/conjugated estrogens (BZA/CE) on menopausal symptoms,... 
Internal Medicine | Obstetrics and Gynecology | breast pain | Bazedoxifene | hot flushes | metabolism | vaginal atrophy | conjugated estrogens | coagulation | PLACEBO | RISK-FACTORS | MEDROXYPROGESTERONE ACETATE | OSTEOPOROSIS | OBSTETRICS & GYNECOLOGY | TRIAL | REPRODUCTIVE BIOLOGY | DISEASE | POSTMENOPAUSAL WOMEN | RECEPTOR MODULATOR | LIPIDS | Carbohydrate Metabolism - drug effects | Estrogens, Conjugated (USP) - pharmacology | Estrogens - pharmacology | Vagina - drug effects | Humans | Middle Aged | Atrophy - pathology | Selective Estrogen Receptor Modulators - adverse effects | Homocysteine - metabolism | Estrogens - adverse effects | Estrogens - therapeutic use | Dose-Response Relationship, Drug | Menopause - drug effects | Selective Estrogen Receptor Modulators - therapeutic use | Adult | Female | Indoles - pharmacology | Atrophy - drug therapy | Drug Therapy, Combination | Vagina - pathology | Hot Flashes - drug therapy | Double-Blind Method | Treatment Outcome | Estrogens, Conjugated (USP) - therapeutic use | Indoles - adverse effects | Menopause - metabolism | Outpatients | Lipid Metabolism - drug effects | Indoles - therapeutic use | Aged | Estrogens, Conjugated (USP) - adverse effects | Selective Estrogen Receptor Modulators - pharmacology | Benzoic acid | Women | Medical colleges | Care and treatment | Safety and security measures | Analysis | Menopause | Estrogen | Health aspects | Index Medicus
Journal Article
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 02/2018, Volume 233, Issue 2, pp. 1041 - 1050
Presently available contraceptives are mostly hormonal or detergent in nature with numerous side effects like irritation, lesion, inflammation in vagina,... 
apoptosis | sperm motility | spermicide | VRP | DNA damage | MICROBIAL-FLORA | PHYSIOLOGY | PROTEIN | MITOCHONDRIA | SPERMATOZOA | PREVENTION | LACTOBACILLI | CELL BIOLOGY | TRIAL | IN-VITRO | SAPONINS | NONOXYNOL-9 | Acrosome - ultrastructure | Acrosome - metabolism | Apoptosis - drug effects | Humans | Sperm Midpiece - drug effects | Male | Spermatozoa - metabolism | Membrane Potential, Mitochondrial - drug effects | Sperm Midpiece - ultrastructure | Dose-Response Relationship, Drug | Mitochondrial Membranes - drug effects | Time Factors | Lactobacillus - drug effects | Cell Membrane - metabolism | Acrosome - drug effects | Cell Membrane - drug effects | Mitochondrial Membrane Transport Proteins - metabolism | Microbial Viability - drug effects | Antimicrobial Cationic Peptides - pharmacology | Mitochondrial Membrane Transport Proteins - drug effects | Cell Membrane - ultrastructure | Permeability | Spermatozoa - drug effects | Mitochondrial Membranes - metabolism | Peptides - pharmacology | Sperm Motility - drug effects | Mitochondrial Membranes - ultrastructure | Sperm Midpiece - metabolism | Spermatocidal Agents - pharmacology | Spermatozoa - ultrastructure | Peptides | Apoptosis | Spermatozoa | Motility | Sperm | Membrane permeability | Vagina | Homeostasis | Microflora | Lactobacillus acidophilus | Assaying | Antiinfectives and antibacterials | Contraceptives | Side effects | Mitochondria | Antimicrobial peptides | Cations | MPTP | Disruption | Deoxyribonucleic acid--DNA | Irritation | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue 11, pp. 4388 - 4393
IgG is a major Ig subclass in mucosal secretions of the human female genital tract, where it predominates over the IgA isotype. Despite the abundance of IgG,... 
Genitalia | Epithelial cells | Secretion | Female genitalia | Cell lines | Antibodies | Human herpesvirus 2 | Infections | Transcytosis | Epithelium | Uterine | Humoral | Mucosa | SIMPLEX-VIRUS TYPE-2 | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | IMMUNOGLOBULIN-G ANTIBODIES | HIV-1-SPECIFIC IGG | MUCOSAL | humoral | IMMUNIZATION | TRANSPORT | EPITHELIAL-CELLS | SECRETIONS | uterine | mucosa | EXPRESSION | Epithelial Cells - metabolism | Antibodies, Viral - pharmacology | Vagina - drug effects | Epithelial Cells - drug effects | Humans | Receptors, Fc - metabolism | Vaginal Diseases - prevention & control | Protein Transport - drug effects | Histocompatibility Antigens Class I - metabolism | Immunity - drug effects | Immunoglobulin G - immunology | Female | Herpesvirus 2, Human - drug effects | Vagina - pathology | Vaginal Diseases - drug therapy | Cell Line | Vaginal Diseases - immunology | Antibodies, Viral - therapeutic use | Histocompatibility Antigens Class I - immunology | Immunity - immunology | Epithelial Cells - pathology | Histocompatibility Antigens Class I - genetics | Gene Expression Regulation - drug effects | Animals | Herpesvirus 2, Human - immunology | Vaginal Diseases - virology | Receptors, Fc - genetics | Vagina - metabolism | Mice | Transcytosis - drug effects | Reproductive organs, Female | Control | Immunoglobulin G | Genetic aspects | Health aspects | Immunity | Vaginosis | Biological Sciences
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 01/2011, Volume 403, Issue 1-2, pp. 262 - 267
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2011, Volume 121, Issue 6, pp. 2401 - 2412
The continued spread of the HIV epidemic underscores the need to interrupt transmission. One attractive strategy is a topical vaginal microbicide. Sexual... 
MEDICINE, RESEARCH & EXPERIMENTAL | BLT MICE | CELLS | MUCOSAL TRANSMISSION | REPLICATION | GENE | RESISTANCE | INFECTION | CCR5 | SMALL INTERFERING RNAS | DELIVERY | Cell Polarity | HIV Infections - prevention & control | Species Specificity | Transplantation Chimera - immunology | Vagina - drug effects | Humans | Molecular Sequence Data | Receptors, CCR5 - genetics | Administration, Intravaginal | Aptamers, Nucleotide - administration & dosage | Gene Knockdown Techniques | CD4-Positive T-Lymphocytes - immunology | Genes, gag | Base Sequence | Female | HIV Infections - transmission | Drug Evaluation, Preclinical | Transplantation Chimera - virology | Macrophages - immunology | Organ Culture Techniques | CD4 Antigens - genetics | Cervix Uteri - drug effects | Cells, Cultured - drug effects | Cervix Uteri - virology | Aptamers, Nucleotide - therapeutic use | Mice, SCID | Genes, vif | Gene Expression Regulation - drug effects | Macrophages - metabolism | Animals | RNA, Small Interfering - therapeutic use | Vagina - virology | Macrophages - drug effects | Mice, Inbred NOD | Cells, Cultured - metabolism | Mice | RNA, Small Interfering - administration & dosage | CD4-Positive T-Lymphocytes - drug effects | CD4 Antigens - metabolism | Infection | Genes | Anti-infective agents | T cells | HIV (Viruses) | Gene expression | Health aspects
Journal Article
Journal Article