X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
valosin containing protein (814) 814
humans (751) 751
index medicus (694) 694
cell cycle proteins - metabolism (546) 546
valosin-containing protein (545) 545
animals (479) 479
adenosine triphosphatases - metabolism (470) 470
cell cycle proteins - genetics (423) 423
biochemistry & molecular biology (418) 418
adenosine triphosphatases - genetics (367) 367
cell biology (340) 340
ubiquitin (304) 304
mutation (248) 248
proteins (246) 246
p97 (243) 243
frontotemporal dementia (220) 220
aaa-atpase (193) 193
adenosine triphosphatases (193) 193
male (189) 189
ubiquitin - metabolism (188) 188
protein binding (186) 186
female (180) 180
mice (179) 179
degradation (166) 166
vcp (166) 166
neurosciences (163) 163
endoplasmic-reticulum (154) 154
article (151) 151
endoplasmic reticulum - metabolism (149) 149
proteasome (143) 143
proteolysis (136) 136
proteasome endopeptidase complex - metabolism (134) 134
inclusion-body myopathy (131) 131
paget-disease (130) 130
clinical neurology (126) 126
saccharomyces-cerevisiae (124) 124
saccharomyces cerevisiae proteins - metabolism (123) 123
middle aged (122) 122
research (120) 120
amino acid sequence (115) 115
adenosine triphosphatase (113) 113
adenosine triphosphatases - chemistry (113) 113
molecular sequence data (113) 113
cell cycle proteins - chemistry (112) 112
amyotrophic-lateral-sclerosis (109) 109
genetic aspects (109) 109
autophagy (105) 105
protein structure, tertiary (105) 105
amyotrophic lateral sclerosis (103) 103
physiological aspects (103) 103
saccharomyces cerevisiae - metabolism (102) 102
analysis (101) 101
cell line (101) 101
nuclear proteins - metabolism (101) 101
ubiquitination (100) 100
signal transduction (97) 97
multidisciplinary sciences (91) 91
aged (90) 90
osteitis deformans - genetics (87) 87
valosin-containing-protein (87) 87
apoptosis (86) 86
cdc48 (86) 86
ubiquitin-protein ligases - metabolism (86) 86
biophysics (85) 85
cancer (85) 85
mutation - genetics (84) 84
cell cycle proteins - physiology (83) 83
complex (82) 82
membrane-fusion (82) 82
phosphorylation (82) 82
protein folding (82) 82
frontotemporal lobar degeneration (80) 80
cell line, tumor (79) 79
models, biological (78) 78
dna-binding proteins - metabolism (77) 77
dementia (76) 76
endoplasmic reticulum (76) 76
proteins - metabolism (75) 75
adult (74) 74
disease (73) 73
myositis, inclusion body - genetics (73) 73
protein (73) 73
research article (73) 73
yeast (73) 73
expression (72) 72
quality-control (72) 72
ubiquitin-proteasome system (72) 72
hela cells (71) 71
molecular biology (70) 70
carrier proteins - metabolism (69) 69
gene expression (69) 69
frontotemporal dementia - genetics (68) 68
hek293 cells (68) 68
membrane proteins - metabolism (68) 68
reticulum-associated degradation (67) 67
saccharomyces cerevisiae - genetics (67) 67
bone (66) 66
cell cycle (66) 66
saccharomyces cerevisiae proteins - genetics (66) 66
models, molecular (65) 65
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1237) 1237
Japanese (13) 13
German (4) 4
Chinese (3) 3
French (1) 1
Hungarian (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


The Journal of Cell Biology, ISSN 0021-9525, 12/2009, Volume 187, Issue 6, pp. 875 - 888
Mutations in valosin-containing protein (VCP) cause inclusion body myopathy (IBM), Paget's disease of the bone, and frontotemporal dementia (IBMPFD). Patient... 
Proteins | Muscular diseases | Transgenic animals | Inclusion bodies | Cell nucleus | Cell lines | Muscles | Small interfering RNA | Frontotemporal dementia | Skeletal muscle | GENE-MUTATIONS | NEURODEGENERATIVE DISEASE | SKELETAL-MUSCLE | IN-VITRO | AAA ATPASE CDC48/P97 | DEMENTIA | INCLUSION-BODY MYOPATHY | TDP-43 ACCUMULATION | FRONTOTEMPORAL LOBAR DEGENERATION | PAGET-DISEASE | CELL BIOLOGY | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Chloroquine | Humans | Valosin Containing Protein | Ubiquitin - metabolism | Recombinant Fusion Proteins - metabolism | Case-Control Studies | Osteitis Deformans - genetics | Osteitis Deformans - chemically induced | DNA-Binding Proteins - metabolism | Myositis, Inclusion Body - enzymology | Transfection | Quadriceps Muscle - enzymology | RNA Interference | Cell Cycle Proteins - genetics | Myositis, Inclusion Body - pathology | Female | Autophagy - genetics | Quadriceps Muscle - pathology | Disease Models, Animal | Frontotemporal Dementia - pathology | Frontotemporal Dementia - genetics | Cell Line | Heat-Shock Proteins - metabolism | Cell Cycle Proteins - metabolism | Adenosine Triphosphatases - metabolism | Mice, Transgenic | Myositis, Inclusion Body - genetics | Osteitis Deformans - enzymology | Osteitis Deformans - pathology | Animals | Biopsy | Frontotemporal Dementia - chemically induced | Frontotemporal Dementia - enzymology | Myositis, Inclusion Body - chemically induced | Adenosine Triphosphatases - genetics | Mice | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Autophagy (Cytology) | Gene mutations | Genetic aspects | Research | Binding proteins | Health aspects | Risk factors | Brain diseases | Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2017, Volume 493, Issue 4, pp. 1384 - 1389
Scaffold proteins play a pivotal role in making protein complexes, and organize binding partners into a functional unit to enhance specific signaling pathways.... 
VCP | Proteomics | IQGAP1 | TARGET | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | PAGET-DISEASE | CDC42 | EFFECTOR | BIOPHYSICS | RAC1 | BINDING | SCAFFOLDING PROTEINS | Immunohistochemistry | ras GTPase-Activating Proteins - chemistry | Humans | Valosin Containing Protein | Osteitis Deformans - metabolism | Osteitis Deformans - genetics | Cell Cycle Proteins - chemistry | Frontotemporal Dementia - metabolism | ras GTPase-Activating Proteins - genetics | Muscular Dystrophies, Limb-Girdle - genetics | HEK293 Cells | Cell Cycle Proteins - genetics | Neurons - metabolism | Protein Interaction Domains and Motifs | Frontotemporal Dementia - genetics | Recombinant Proteins - metabolism | ras GTPase-Activating Proteins - metabolism | Mutagenesis, Site-Directed | Cell Cycle Proteins - metabolism | Mutant Proteins - genetics | Adenosine Triphosphatases - metabolism | Recombinant Proteins - chemistry | Mutant Proteins - metabolism | Recombinant Proteins - genetics | Myositis, Inclusion Body - genetics | Hippocampus - metabolism | Muscular Dystrophies, Limb-Girdle - metabolism | Mutant Proteins - chemistry | Adenosine Triphosphatases - chemistry | Myositis, Inclusion Body - metabolism | Adenosine Triphosphatases - genetics | HeLa Cells | Amino Acid Substitution | Proteins | Physiological aspects | Protein binding | Medical colleges | Neurons | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2016, Volume 291, Issue 14, pp. 7396 - 7408
Cockayne syndrome group A and B (CSB) proteins act in transcription-coupled repair, a subpathway of nucleotide excision repair. Here we demonstrate that... 
RNA-POLYMERASE-II | UV-SENSITIVE SYNDROME | UBIQUITIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | IN-VIVO | AAA-ATPASE | DOUBLE-STRAND BREAKS | XPC | TRANSCRIPTION-COUPLED REPAIR | NUCLEOTIDE EXCISION-REPAIR | Chromatin - metabolism | Valosin Containing Protein | DNA Repair Enzymes - genetics | Hexosyltransferases - metabolism | LIM Domain Proteins - metabolism | DNA-Binding Proteins - metabolism | Poly-ADP-Ribose Binding Proteins | Proteolysis | DNA Repair Enzymes - metabolism | Cell Cycle Proteins - genetics | Cullin Proteins - metabolism | DNA Helicases - genetics | Cell Line | ATPases Associated with Diverse Cellular Activities | Cell Cycle Proteins - metabolism | Hexosyltransferases - genetics | Adenosine Triphosphatases - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Ultraviolet Rays - adverse effects | Cullin Proteins - genetics | Proteasome Endopeptidase Complex - genetics | Proteins - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | DNA Helicases - metabolism | Carrier Proteins - metabolism | Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | LIM Domain Proteins - genetics | Ubiquitination - radiation effects | Adenosine Triphosphatases - genetics | DNA Damage | Proteasome Endopeptidase Complex - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Chromatin - genetics | Ubiquitination - genetics | Cockayne syndrome group B protein | DNA and Chromosomes | valosin-containing protein | DNA damage | DNA repair | nucleotide excision repair | protein degradation | ubiquitin | transcription-coupled repair
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 11002 - 15
In recent years, multiple studies including ours have reported on the mechanism of resistance towards valosin-containing protein (VCP) inhibitors. While all... 
TARGET | CLEARANCE | P97 AAA-ATPASE | MULTIDISCIPLINARY SCIENCES | DISEASE | VCP/P97 | DEGRADATION | CANCER | Proteins | CRISPR | Zygosity | Transcription | Alleles | Frameshift mutation | Mutation | Deoxyribonucleic acid--DNA | Valosin-containing protein | DNA sequencing
Journal Article
Journal of Neuropathology and Experimental Neurology, ISSN 0022-3069, 06/2006, Volume 65, Issue 6, pp. 571 - 581
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2011, Volume 13, Issue 9, pp. 1116 - 1124
The AAA-ATPase VCP (also known as p97) cooperates with distinct cofactors to process ubiquitylated proteins in different cellular pathways(1-3). VCP missense... 
UBIQUITIN-SELECTIVE CHAPERONE | VALOSIN-CONTAINING PROTEIN | COMPLEX | FRONTOTEMPORAL DEMENTIA | CDC48/P97 | AAA-ATPASE | ENDOPLASMIC-RETICULUM | MYOPATHY | PAGET-DISEASE | P97 | CELL BIOLOGY | Humans | Valosin Containing Protein | Endosomal Sorting Complexes Required for Transport - genetics | Endosomes - metabolism | Lysosomes - metabolism | RNA Interference | Mass Spectrometry | Endosomes - ultrastructure | HEK293 Cells | Cell Cycle Proteins - genetics | Sarcolemma - metabolism | Ubiquitinated Proteins - metabolism | Muscular Diseases - metabolism | Cell Cycle Proteins - metabolism | Cells, Cultured | Endosomal Sorting Complexes Required for Transport - metabolism | Adenosine Triphosphatases - metabolism | Caveolin 1 - genetics | Rats | Muscular Diseases - pathology | Microscopy, Electron | Blotting, Western | Caveolin 1 - metabolism | Lysosomes - ultrastructure | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Cell Line, Tumor | Protein Binding | Luminescent Proteins - genetics | Ubiquitinated Proteins - genetics | Adenosine Triphosphatases - genetics | Muscular Diseases - genetics | Mutation | Microscopy, Fluorescence | Luminescent Proteins - metabolism | Usage | Degeneration (Pathology) | Gene mutations | Genetic aspects | Diagnosis | Research | Mass spectrometry | Health aspects | Risk factors
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1761, Volume 289, Issue 18, pp. 12264 - 12274
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 11519 - 9
Reduced adenosine triphosphate (ATP) levels in ischemic stroke constitute an upstream contributor to neuronal cell death. We have recently created a small... 
SURVIVAL | MYELIN | MODELS | MULTIDISCIPLINARY SCIENCES | RANDOMIZED-TRIAL | DEATH | MECHANISMS | GLUCOSE DEPRIVATION | STRESS | ISCHEMIA/REPERFUSION | OLIGODENDROCYTES | Cerebral infarction | Neuroprotection | Cell culture | Stroke | Animal models | Cortex | Ischemia | Cell death | Cerebral blood flow | ATP | Adenosine triphosphate | Valosin-containing protein | Apoptosis
Journal Article
Journal Article
Journal Article