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Neurology, ISSN 0028-3878, 2009, Volume 73, Issue 2, pp. 142 - 149
Journal Article
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 01/2011, Volume 31, Issue 1, pp. 52 - 57
Journal Article
Epilepsia, ISSN 0013-9580, 01/2012, Volume 53, Issue 1, pp. 120 - 128
Summary Purpose:  Long‐term therapy with antiepileptic drugs (AEDs) has been associated with metabolic consequences that lead to an increase in risk of... 
Antiepileptic drugs | Monotherapy | Vascular risk factors | Atherosclerosis | Intima media thickness | INTIMA-MEDIA THICKNESS | MORTALITY | HOMOCYSTEINE | MYOCARDIAL-INFARCTION | CARBAMAZEPINE | FOLIC-ACID | CLINICAL NEUROLOGY | SODIUM VALPROATE | URIC-ACID | CARDIOVASCULAR RISK | EPILEPTIC CHILDREN | Follow-Up Studies | Humans | Middle Aged | Anticonvulsants - administration & dosage | Male | Young Adult | Anticonvulsants - adverse effects | Carbamazepine - administration & dosage | Time Factors | Adult | Female | Uric Acid - blood | Valproic Acid - adverse effects | Cross-Sectional Studies | Atherosclerosis - chemically induced | Risk Factors | Homocysteine - blood | Phenytoin - administration & dosage | Blood Glucose - drug effects | Carbamazepine - adverse effects | Valproic Acid - administration & dosage | Phenytoin - adverse effects | Carotid Artery, Common - drug effects | Adolescent | Folic Acid - blood | Carotid Artery, Common - pathology | Epilepsy - drug therapy | Aged | Medical colleges | Anticonvulsants | Blood sugar | Epilepsy | Uric acid | Homocysteine | Risk factors | Cholesterol | Folic acid | Enzymes | Acids | Drugs | C-reactive protein | Fasting | lamotrigine | thiobarbituric acid | Antiepileptic agents | Metabolism | Valproic acid | Carbamazepine | Body mass index | Arteriosclerosis | Carotid artery | Phenytoin | Sugar | Long-term effects
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 06/2012, Volume 121, Issue 5, pp. 818 - 829
J. Neurochem. (2012) 121, 818–829. The disruption of blood–spinal cord barrier (BSCB) after spinal cord injury (SCI) elicits an intensive local inflammation by... 
matrix metalloprotease | spinal cord injury | blood–spinal cord barrier | inflammation | histone deacetylase inhibitor | tight junction | blood-spinal cord barrier | ACTIVATION | PROTEIN | HISTONE DEACETYLASE INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOCAL CEREBRAL-ISCHEMIA | POTENTIAL ROLES | NEUROSCIENCES | CELL-DEATH | BRAIN-BARRIER | INTRACEREBRAL HEMORRHAGE | RAT-BRAIN | EXPRESSION | Immunohistochemistry | In Situ Nick-End Labeling | Enzyme-Linked Immunosorbent Assay | Recovery of Function - drug effects | Capillary Permeability - drug effects | Rats | Male | Reverse Transcriptase Polymerase Chain Reaction | Rats, Sprague-Dawley | Valproic Acid - pharmacology | Blotting, Western | Spinal Cord Injuries - pathology | Matrix Metalloproteinase 9 - metabolism | Animals | Neuroprotective Agents - pharmacology | Spinal Cord Injuries - enzymology | Histone Deacetylase Inhibitors - pharmacology | Neurochemistry | Leucocytes | Spinal cord injuries | Pharmacology | Protease inhibitors | Cellular biology | Histone deacetylase | Tight junctions | Therapeutic applications | Blood cells | Heat shock proteins | Recovery of function | Inflammation | Permeability | Macrophages | Spinal cord injury | Valproic acid | Caspase-3 | Gelatinase B | Zonula occludens-1 protein | Metastases | Cell death | Chromium | Tumor necrosis factor- alpha | Apoptosis
Journal Article
Nuclear Medicine and Biology, ISSN 0969-8051, 2013, Volume 40, Issue 7, pp. 912 - 918
Abstract The fatty acids, n -butyric acid (BA), 4-phenylbutyric acid (PBA) and valproic acid (VPA, 2-propylpentanoic acid) have been used for many years in the... 
Radiology | Histone deacetylase (HDAC) | [11C]4-phenylbutyric acid | [11C]butyric acid | Pharmacokinetics | Positron emission tomography | 11C]valproic acid | C]4-phenylbutyric acid | C]butyric acid | C]valproic acid | BETA-GLOBIN DISORDERS | C-11]valproic acid | ULCERATIVE-COLITIS | [C-11]4-phenylbutyric acid | MEMORY | DISEASE MOUSE MODEL | SODIUM-BUTYRATE | IN-VIVO | PHENYLBUTYRATE | INCREASED FETAL-HEMOGLOBIN | HISTONE DEACETYLASE INHIBITORS | [C-11]butyric acid | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | COLONIC-MUCOSA | Phenylbutyrates - blood | Valproic Acid - pharmacokinetics | Brain - diagnostic imaging | Positron-Emission Tomography | Blood Proteins - metabolism | Histone Deacetylase Inhibitors - blood | Brain - metabolism | Papio | Tissue Distribution | Histone Deacetylase Inhibitors - pharmacokinetics | Animals | Butyric Acid - metabolism | Phenylbutyrates - pharmacokinetics | Phenylbutyrates - metabolism | Radiochemistry | Valproic Acid - blood | Butyric Acid - pharmacokinetics | Isotope Labeling | Female | Histone Deacetylase Inhibitors - metabolism | Butyric Acid - blood | Valproic Acid - metabolism | Carbon Radioisotopes | Drugs | Divalproex | Valproic acid | Saturated fatty acids | Organic acids | Index Medicus | RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY | phamacokinetics | 11C (Carbon 11) | [11C]PBA (4-phenylbutyric acid) | PET (positron emission tomography) | HDAC (histone deacetylase) | [11C]VPA (valproic acid) | [11C]BA (butyric acid) | [11C]valproic acid | pharmacokinetics | carbon-11 | histone deacetylase (HDAC) | positron emission tomography
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2015, Volume 92, Issue 5, pp. 986 - 992
Purpose Valproic acid (VPA) is an antiepileptic agent with histone deacetylase inhibitor (HDACi) activity shown to sensitize glioblastoma (GBM) cells to... 
Radiology | Hematology, Oncology and Palliative Medicine | PLUS TEMOZOLOMIDE | MALIGNANT GLIOMA | SURVIVAL | ONCOLOGY | NEWLY-DIAGNOSED GLIOBLASTOMA | CONCOMITANT | RANDOMIZED-TRIAL | RADIOTHERAPY | MULTIFORME | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | ERLOTINIB | ADJUVANT TEMOZOLOMIDE | Multivariate Analysis | Dacarbazine - adverse effects | Age Factors | Dacarbazine - therapeutic use | Humans | Middle Aged | Male | Bone Marrow - radiation effects | Glioblastoma - radiotherapy | Radiation-Sensitizing Agents - administration & dosage | Time Factors | Brain Neoplasms - blood | Dacarbazine - analogs & derivatives | Valproic Acid - blood | Adult | Female | Brain Neoplasms - mortality | Chemotherapy, Adjuvant | Brain Neoplasms - radiotherapy | Valproic Acid - adverse effects | Bone Marrow - drug effects | Chemoradiotherapy - methods | Drug Administration Schedule | Glioblastoma - blood | Kaplan-Meier Estimate | Brain Neoplasms - drug therapy | Radiation-Sensitizing Agents - adverse effects | Disease Progression | Antineoplastic Agents, Alkylating - therapeutic use | Radiation Tolerance - drug effects | Disease-Free Survival | Valproic Acid - administration & dosage | Radiation-Sensitizing Agents - metabolism | Aged | Histone Deacetylase Inhibitors - therapeutic use | Antineoplastic Agents, Alkylating - adverse effects | Glioblastoma - drug therapy | Glioblastoma - mortality | Histone Deacetylase Inhibitors - adverse effects | Divalproex | Care and treatment | Analysis | Radiation | Temozolomide | Radiotherapy | Valproic acid | Glioblastoma multiforme | Index Medicus | GLIOMAS | DIAGNOSIS | PATIENTS | DISEASE INCIDENCE | RADIOLOGY AND NUCLEAR MEDICINE | BONE MARROW | RADIATION DOSES | TOXICITY | COMPARATIVE EVALUATIONS | BLOOD
Journal Article
Acta Neurologica Scandinavica, ISSN 0001-6314, 03/2004, Volume 109, Issue 3, pp. 159 - 168
Journal Article
Journal Article
Journal of Analytical Toxicology, ISSN 0146-4760, 10/2016, Volume 40, Issue 8, pp. 649 - 652
Journal Article