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Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2007, Volume 292, Issue 2, pp. 758 - 766
Hypoxia-inducible factor (HIF)-1 activation in response to hypoxia requires mitochondrial generation of reactive oxygen species (ROS). In contrast, the... 
Gene expression | Reduced nicotinamide adenine dinucleotide phosphate oxidase | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Transcription, Genetic - drug effects | Reactive Oxygen Species - metabolism | Humans | Reactive Oxygen Species - pharmacology | NADPH Oxidases - metabolism | Protein Tyrosine Phosphatases - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Hepatocytes - metabolism | Promoter Regions, Genetic - drug effects | Hypoxia-Inducible Factor 1 - metabolism | Promoter Regions, Genetic - genetics | Hypoxia-Inducible Factor 1 - genetics | Dose-Response Relationship, Drug | Protein Tyrosine Phosphatases - antagonists & inhibitors | Thiocarbamates - pharmacology | Transfection | Time Factors | Vanadates - pharmacology | Acetophenones - pharmacology | Proline - pharmacology | Hepatocytes - drug effects | DNA - drug effects | Insulin - pharmacology | Proline - analogs & derivatives | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Antioxidants - pharmacology | DNA - metabolism | Onium Compounds - pharmacology | Hydrogen Peroxide - metabolism | Gene Expression Regulation - drug effects | Insulin - metabolism | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | Cell Line, Tumor | Myocytes, Cardiac - metabolism | Receptor, Insulin - drug effects | Receptor, Insulin - metabolism | Enzymes | Hypoxia | Oxygen | Insulin | Index Medicus
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 11/2001, Volume 70, Issue 5, pp. 830 - 838
5‐Lipoxygenase (5‐LO), which catalyzes the first two steps in leukotriene biosynthesis, is a target for pharmacological treatment of inflammatory disorders.... 
mitogen-activated protein kinase | sodium arsenite | heat shock protein | 5-lipoxygenase | Mono Mac 6 | hypertonicity | Mitogen-activated protein kinase | Hypertonicity | Sodium arsenite | Heat shock protein | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Biology | Arsenites - pharmacology | Osmotic Pressure | Arachidonic Acid - metabolism | Oxidative Stress | Protein-Serine-Threonine Kinases | Hypertonic Solutions - pharmacology | Hydroxyeicosatetraenoic Acids - biosynthesis | Protein Tyrosine Phosphatases - antagonists & inhibitors | Calcium - physiology | Protein Processing, Post-Translational - drug effects | Vanadates - pharmacology | Sorbitol - administration & dosage | Phosphorylation - drug effects | p38 Mitogen-Activated Protein Kinases | Arachidonate 5-Lipoxygenase - analysis | B-Lymphocytes - metabolism | Ionophores - pharmacology | Cell Line | Arachidonate 5-Lipoxygenase - metabolism | Enzyme Inhibitors - pharmacology | Leukotrienes - biosynthesis | Intracellular Signaling Peptides and Proteins | Imidazoles - pharmacology | Sodium Compounds - pharmacology | Calcimycin - pharmacology | Interleukin-1 - pharmacology | B-Lymphocytes - drug effects | Transforming Growth Factor beta - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Cell-Free System | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mitogen-Activated Protein Kinases - physiology | Protein Kinases | Thapsigargin - pharmacology | Pyridines - pharmacology | Enzyme Activation | Lipoxygenase Inhibitors - pharmacology | Subcellular Fractions - enzymology | Mitogen-Activated Protein Kinases - metabolism | Protein Tyrosine Phosphatases - physiology | Index Medicus
Journal Article
Journal Article
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 07/2007, Volume 293, Issue 1, pp. 390 - 400
Hypotonic exposure provokes the mobilization of arachidonic acid, production of ROS, and a transient increase in taurine release in Ehrlich Lettre cells. The... 
Vanadate | Reactive oxygen species | Arachidonic acid mobilization | Organic osmolytes | Tyrosine phosphatases | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | NIH 3T3 Cells | Arachidonic Acid - metabolism | Reactive Oxygen Species - metabolism | Reactive Oxygen Species - pharmacology | NADPH Oxidases - metabolism | Protein Tyrosine Phosphatases - metabolism | Phospholipases A - metabolism | Carcinoma, Ehrlich Tumor - metabolism | Pyrones - pharmacology | Hypotonic Solutions - metabolism | Dose-Response Relationship, Drug | Terpenes - pharmacology | Protein Tyrosine Phosphatases - antagonists & inhibitors | Time Factors | Vanadates - pharmacology | Sodium Chloride - metabolism | Carcinoma, Ehrlich Tumor - pathology | Fibroblasts - metabolism | Arachidonate 5-Lipoxygenase - metabolism | Cell Size - drug effects | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Hydrogen Peroxide - pharmacology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Naphthalenes - pharmacology | Animals | Signal Transduction - drug effects | Fibroblasts - drug effects | Cell Line, Tumor | Phospholipases A - antagonists & inhibitors | Mice | Lipoxygenase Inhibitors - pharmacology | Taurine - metabolism | Antioxidants | Enzymes | Acids | Chemical compounds | Cells | Index Medicus
Journal Article
Investigational new drugs, ISSN 0167-6997, 8/2012, Volume 30, Issue 4, pp. 1302 - 1310
Journal Article
Journal Article