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Cell Stem Cell, ISSN 1934-5909, 11/2016, Volume 19, Issue 5, pp. 628 - 642
Journal Article
Circulation Research, ISSN 0009-7330, 04/2015, Volume 116, Issue 8, pp. 1312 - 1323
Rationale: Matrix vesicles (MVs), secreted by vascular smooth muscle cells (VSMCs), form the first nidus for mineralization and fetuin-A, a potent circulating... 
exosomes | extracellular matrix | vascular calcification | CALCIPROTEIN PARTICLES | CARDIAC & CARDIOVASCULAR SYSTEMS | PROTEIN | RETICULOCYTE MATURATION | EXTRACELLULAR CALCIUM | MATRIX VESICLES | HUMAN ATHEROSCLEROTIC PLAQUES | MULTIVESICULAR ENDOSOMES | ARTERIAL CALCIFICATION | PERIPHERAL VASCULAR DISEASE | CHRONIC KIDNEY-DISEASE | HEMATOLOGY | FETUIN-A | Exosomes - metabolism | Sphingomyelin Phosphodiesterase - genetics | Muscle, Smooth, Vascular - metabolism | Calcium - metabolism | Humans | Middle Aged | Vascular Calcification - genetics | Myocytes, Smooth Muscle - pathology | Secretory Vesicles - metabolism | Exosomes - pathology | Male | Exocytosis | Case-Control Studies | Young Adult | Intercellular Signaling Peptides and Proteins - metabolism | Vascular Calcification - metabolism | Transfection | RNA Interference | Time Factors | Sphingomyelin Phosphodiesterase - metabolism | Vascular Calcification - physiopathology | Adult | Female | Proteomics - methods | Tetraspanins - metabolism | Myocytes, Smooth Muscle - metabolism | Exosomes - secretion | Cytokines - metabolism | Cells, Cultured | Vascular Calcification - pathology | Myocytes, Smooth Muscle - secretion | Protein Transport | Secretory Vesicles - secretion | Muscle, Smooth, Vascular - pathology | Adolescent | alpha-2-HS-Glycoprotein - metabolism | Secretory Vesicles - pathology | Muscle, Smooth, Vascular - secretion | Index Medicus
Journal Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 01/2015, Volume 29, Issue 1, pp. 173 - 181
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2016, Volume 126, Issue 4, pp. 1323 - 1336
Vascular calcification is a common feature of major cardiovascular diseases. Extracellular vesicles participate in the formation of microcalcifications that... 
MEDICINE, RESEARCH & EXPERIMENTAL | MYOCARDIAL-INFARCTION | NONSPECIFIC ALKALINE-PHOSPHATASE | MINERALIZATION | TRANS-GOLGI NETWORK | CARDIOVASCULAR-DISEASE | ATHEROSCLEROSIS | MATRIX VESICLES | PROTEINS | MASS-SPECTROMETRY | GENOME-WIDE ASSOCIATION | Phosphorylation | Muscle, Smooth, Vascular - metabolism | Casein Kinase I - genetics | Humans | Vascular Calcification - genetics | Adaptor Proteins, Vesicular Transport - genetics | Myocytes, Smooth Muscle - pathology | rab GTP-Binding Proteins - genetics | Adaptor Proteins, Vesicular Transport - metabolism | Vascular Calcification - metabolism | Cell-Derived Microparticles - metabolism | Plaque, Atherosclerotic - pathology | Myocytes, Smooth Muscle - metabolism | Extracellular Matrix Proteins - metabolism | Calcium-Binding Proteins - metabolism | rab GTP-Binding Proteins - metabolism | Alkaline Phosphatase - genetics | Plaque, Atherosclerotic - metabolism | Cell-Derived Microparticles - genetics | Carrier Proteins - biosynthesis | Extracellular Matrix Proteins - genetics | Cells, Cultured | Vascular Calcification - pathology | Mice, Knockout | Protein Transport | Carrier Proteins - genetics | Muscle, Smooth, Vascular - pathology | Animals | Alkaline Phosphatase - biosynthesis | Casein Kinase I - metabolism | Mice | Casein Kinase II - metabolism | Calcium-Binding Proteins - genetics | Calcification | Phosphatases | Cellular proteins | Molecular targeted therapy | Innovations | Development and progression | Genetic aspects | Properties | Coronary heart disease | Proteins | Statistical analysis | Rodents | Acute coronary syndromes | Metabolism | Experiments | Manuscripts | Carotid arteries | Veins & arteries | Index Medicus | Abridged Index Medicus
Journal Article
Kidney International, ISSN 0085-2538, 05/2014, Volume 85, Issue 5, pp. 1103 - 1111
Fibroblast growth factor 23 (FGF23) is a phosphate-regulating hormone that acts primarily on the kidney and parathyroid. With declining kidney function there... 
phosphate | chronic kidney disease | Klotho | fibroblast growth factor 23 | vascular calcification | Vascular calcification | Chronic kidney disease | Fibroblast growth factor 23 | Phosphate | VITAMIN-D | AORTIC CALCIFICATION | OSTEOBLAST DIFFERENTIATION | CARDIOVASCULAR EVENTS | FGF RECEPTOR 1 | ENDOTHELIAL-CELLS | ARTERIAL CALCIFICATION | HEMODIALYSIS-PATIENTS | UROLOGY & NEPHROLOGY | SMOOTH-MUSCLE-CELLS | CHRONIC KIDNEY-DISEASE | Phosphorylation | Muscle, Smooth, Vascular - metabolism | Glucuronidase - metabolism | Myocytes, Smooth Muscle - pathology | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Male | Aorta - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Renal Insufficiency, Chronic - complications | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Aortic Diseases - chemically induced | Aortic Diseases - metabolism | Glucuronidase - deficiency | Dose-Response Relationship, Drug | Renal Insufficiency, Chronic - metabolism | Fibroblast Growth Factors - metabolism | Vascular Calcification - metabolism | Transfection | Phosphates - toxicity | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Aortic Diseases - pathology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Aorta - drug effects | Osteoblasts - drug effects | Cells, Cultured | Vascular Calcification - pathology | Rats, Sprague-Dawley | Aorta - pathology | Osteoblasts - pathology | Muscle, Smooth, Vascular - pathology | Animals | Glucuronidase - genetics | Signal Transduction - drug effects | Cell Differentiation - drug effects | Vascular Calcification - chemically induced | Recombinant Proteins - toxicity | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Osteoblasts - metabolism | Fibroblast Growth Factors - toxicity | Index Medicus
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2018, Volume 38, Issue 3, pp. 575 - 587
Journal Article
Kidney International, ISSN 0085-2538, 06/2013, Volume 83, Issue 6, pp. 1042 - 1051
Autophagy is a dynamic and highly regulated process of self-digestion responsible for cell survival and reaction to oxidative stress. As oxidative stress is... 
apoptosis | autophagy | chronic renal failure | hyperphosphatemia | oxidative stress | Hyperphosphatemia | Oxidative stress | Chronic renal failure | Autophagy | Apoptosis | PRIMARY CULTURE | INORGANIC-PHOSPHATE | DEATH | CALCIUM | DISEASE | GROWTH | UROLOGY & NEPHROLOGY | SMOOTH-MUSCLE-CELLS | BETA-GLYCEROPHOSPHATE | SELF-DIGESTION | Caspase Inhibitors - pharmacology | Superoxide Dismutase - genetics | Muscle, Smooth, Vascular - metabolism | Alkaline Phosphatase - metabolism | Myocytes, Smooth Muscle - pathology | Secretory Vesicles - metabolism | Metalloporphyrins - pharmacology | Valproic Acid - pharmacology | Autophagy - drug effects | Sodium-Phosphate Cotransporter Proteins, Type III - genetics | Vascular Calcification - metabolism | Transfection | RNA Interference | Time Factors | Amino Acid Chloromethyl Ketones - pharmacology | Cattle | Kidney Failure, Chronic - pathology | Vascular Calcification - etiology | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Superoxide Dismutase - metabolism | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Adenine - analogs & derivatives | Cells, Cultured | Rats | Vascular Calcification - prevention & control | Adenine - pharmacology | Antioxidants - pharmacology | Vascular Calcification - pathology | Kidney Failure, Chronic - metabolism | Proteins - genetics | Muscle, Smooth, Vascular - pathology | Phosphates - metabolism | Animals | Proteins - metabolism | Autophagy-Related Protein 5 | Secretory Vesicles - drug effects | Kidney Failure, Chronic - complications | Secretory Vesicles - pathology | Sodium-Phosphate Cotransporter Proteins, Type III - metabolism | Index Medicus
Journal Article
Atherosclerosis, ISSN 0021-9150, 2012, Volume 221, Issue 2, pp. 387 - 396
Highlights ► STZ–CML–HFD for 4 months could induce atherosclerotic calcification of diabetes. ► We constructed a new calcification model in a high-lipid,... 
Cardiovascular | Advanced glycation end-products | Phenotype transformation | OSTEOGENIC DIFFERENTIATION | RECEPTOR | MECHANISMS | RAGE | CORONARY-ARTERY CALCIFICATION | Atherosclerosis | DISEASE | Vascular calcification | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | INTRAVASCULAR ULTRASOUND | APOPTOTIC BODIES | Diabetes | Vascular smooth muscle cells | Apoptosis | Immunohistochemistry | Apolipoproteins E - deficiency | Atherosclerosis - genetics | Alkaline Phosphatase - metabolism | Diabetic Angiopathies - etiology | Male | Vascular Calcification - metabolism | Time Factors | Vascular Calcification - etiology | Diet, High-Fat | Cell Differentiation | Diabetes Mellitus, Experimental - complications | Lipoproteins, LDL - metabolism | Lysine - metabolism | Receptor for Advanced Glycation End Products | Lysine - analogs & derivatives | Atherosclerosis - pathology | Core Binding Factor Alpha 2 Subunit - metabolism | Macrophages - pathology | Lysine - administration & dosage | Rats | Vascular Calcification - pathology | Atherosclerosis - metabolism | Blotting, Western | Disease Progression | Mice, Knockout | Macrophages - metabolism | Staining and Labeling | Glucose - metabolism | Mice | Injections, Intravenous | Muscle, Smooth, Vascular - metabolism | Vascular Calcification - genetics | Myocytes, Smooth Muscle - pathology | Atherosclerosis - etiology | Diabetic Angiopathies - pathology | Bone Morphogenetic Protein 2 - metabolism | Diabetes Mellitus, Experimental - metabolism | Diabetic Angiopathies - genetics | Myocytes, Smooth Muscle - metabolism | Cell Line | Diabetic Angiopathies - metabolism | Mice, Inbred C57BL | Muscle, Smooth, Vascular - pathology | Animals | Apolipoproteins E - genetics | Osteogenesis | Receptors, Immunologic - metabolism | Index Medicus
Journal Article