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Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2009, Volume 69, Issue 9, pp. 4001 - 4009
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2005, Volume 25, Issue 2, pp. 334 - 340
OBJECTIVE—Expression of adhesion molecules on endothelial cells and subsequent leukocyte recruitment are critical early events in the development of... 
Superoxide dismutase | Endothelial cell | Adhesion molecule | Atherosclerosis | MAPKs | atherosclerosis | ACTIVATION | INDUCED APOPTOSIS | endothelial cell | adhesion molecule | MAP KINASES | INDUCTION | AP-1 | SIGNAL-TRANSDUCTION | IN-VITRO | superoxide dismutase | VCAM-1 EXPRESSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | NF-KAPPA-B | Endothelium, Vascular - cytology | Neutrophils - cytology | Transcription, Genetic - drug effects | MAP Kinase Signaling System - physiology | Phosphorylation | Superoxide Dismutase - genetics | Humans | Recombinant Fusion Proteins - physiology | Depression, Chemical | Superoxide Dismutase - physiology | Intercellular Adhesion Molecule-1 - biosynthesis | Superoxides - metabolism | Vascular Cell Adhesion Molecule-1 - genetics | Flavonoids - pharmacology | NF-kappa B - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Transduction, Genetic | p38 Mitogen-Activated Protein Kinases - physiology | Endothelial Cells - metabolism | NADPH Oxidases - antagonists & inhibitors | Imidazoles - pharmacology | Inflammation | Cell Adhesion - drug effects | Anthracenes - pharmacology | Gene Expression Regulation - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Arteriosclerosis - prevention & control | Transcription Factor AP-1 - antagonists & inhibitors | MAP Kinase Signaling System - drug effects | Cell Adhesion - physiology | Endothelium, Vascular - metabolism | Intercellular Adhesion Molecule-1 - genetics | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - physiology | Vascular Cell Adhesion Molecule-1 - biosynthesis | Protein Processing, Post-Translational | Pyridines - pharmacology | Aorta - cytology | Superoxide Dismutase-1 | Index Medicus
Journal Article
Journal Article
Atherosclerosis, ISSN 0021-9150, 2005, Volume 183, Issue 2, pp. 259 - 267
In this study the effects of stable and intermittent high glucose concentrations on ICAM-1, VCAM-1 and E-selectin production, PKC activity and PKCβI, βII and δ... 
Adhesion molecules | PKC | Mitochondrial superoxide | Intermittent glucose | Endothelium | endothelium | OXIDATIVE STRESS | ACTIVATION | CIRCULATING ADHESION MOLECULES | BLOOD-GLUCOSE | ATHEROSCLEROSIS | MECHANISMS | intermittent glucose | DIABETES-MELLITUS | mitochondrial superoxide | HYPERGLYCEMIA | adhesion molecules | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | COMPLICATIONS | Endothelium, Vascular - cytology | Mitochondria - enzymology | Vascular Cell Adhesion Molecule-1 - drug effects | Gene Expression - drug effects | Humans | Glucose - administration & dosage | Dose-Response Relationship, Drug | RNA, Messenger - biosynthesis | E-Selectin - genetics | Protein Kinase C - metabolism | Intercellular Adhesion Molecule-1 - biosynthesis | E-Selectin - biosynthesis | Superoxides - metabolism | Intercellular Adhesion Molecule-1 - drug effects | Vascular Cell Adhesion Molecule-1 - genetics | E-Selectin - drug effects | Umbilical Veins - cytology | Deoxyguanosine - analogs & derivatives | Infant, Newborn | Enzyme-Linked Immunosorbent Assay | Protein Kinase C - drug effects | RNA, Messenger - genetics | Cells, Cultured | Blotting, Western | Blotting, Northern | Endothelium, Vascular - metabolism | Intercellular Adhesion Molecule-1 - genetics | Deoxyguanosine - metabolism | Vascular Cell Adhesion Molecule-1 - biosynthesis | Oxidative Stress - drug effects | In Vitro Techniques | Sweetening Agents - administration & dosage | Umbilical Veins - metabolism | Messenger RNA | Atherosclerosis | Superoxide | Glucose | Protein kinases | Dextrose | Porphyrins | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2011, Volume 286, Issue 8, pp. 6423 - 6432
FoxO1, a forkhead box O class transcription factor, is abundant in insulin-responsive tissues. Akt, downstream from phosphatidylinositol 3-kinase in insulin... 
STIMULATES PHOSPHORYLATION | ACTIVATION | ANGIOGENESIS | METABOLISM | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PKA | INVOLVEMENT | MECHANISMS | CAMP | FORKHEAD TRANSCRIPTION FACTORS | Phosphorylation - physiology | RNA, Small Interfering - genetics | Humans | Transcriptional Activation - drug effects | Monocytes - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | Isoquinolines - pharmacology | Cattle | Forkhead Transcription Factors - metabolism | HEK293 Cells | Vascular Cell Adhesion Molecule-1 - genetics | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Endothelial Cells - metabolism | Cell Adhesion - drug effects | Forkhead Transcription Factors - genetics | Sulfonamides - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Animals | Cell Adhesion - physiology | Endothelial Cells - cytology | Vascular Cell Adhesion Molecule-1 - biosynthesis | Forkhead Box Protein O1 | Protein Kinase Inhibitors - pharmacology | Transcriptional Activation - physiology | Mutation | Protein kinase A | Alanine | Phosphorylation | Transcription factors | Antibodies | AKT protein | siRNA | Insulin | Endothelial cells | Promoters | 1-Phosphatidylinositol 3-kinase | Monocytes | Prostaglandins | FOXO1 protein | Aorta | Forkhead protein | Tumor necrosis factor- alpha | Antigen-antibody complexes | Index Medicus | Protein Kinase A (PKA) | VCAM-1 | Signal Transduction | Transcription Factors | Akt PKB | Endothelium | Protein-Protein Interactions | FoxO1
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 12/1999, Volume 100, Issue 25, pp. 2473 - 2476
Background-Among the many adipocyte-derived endocrine factors, we recently found an adipocyte-specific secretory protein, adiponectin, which was decreased in... 
Coronary disease | Adiponectin | Cell adhesion molecules | Endothelium | endothelium | adiponectin | cell adhesion molecules | VISCERAL FAT | CARDIAC & CARDIOVASCULAR SYSTEMS | ATHEROSCLEROSIS | SELECTIN | coronary disease | OBESITY | GENE | CLONING | DISEASE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION | ADIPOSE | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 02/2006, Volume 91, Issue 2, pp. 546 - 554
Context: An increasing body of evidence suggests that testosterone may exert beneficial effects on the development of atherosclerosis. It was suggested that... 
ACTIVATION | CAROTID ATHEROSCLEROSIS | EPITHELIAL-CELLS | TESTOSTERONE | ENDOCRINOLOGY & METABOLISM | CYCLOOXYGENASE-2 EXPRESSION | MECHANISMS | DEPENDENT PATHWAY | ELDERLY-MEN | CORONARY-ARTERY-DISEASE | ADHESION MOLECULE-1 EXPRESSION | Androgen Receptor Antagonists | Platelet Endothelial Cell Adhesion Molecule-1 - genetics | Humans | Immunoblotting | NF-kappa B - metabolism | Cyclooxygenase 2 - biosynthesis | RNA, Messenger - biosynthesis | Inflammation - metabolism | Drug Interactions | Cyclooxygenase 2 - genetics | E-Selectin - genetics | Inflammation - drug therapy | Intercellular Adhesion Molecule-1 - biosynthesis | E-Selectin - biosynthesis | Dihydrotestosterone - pharmacology | Nitriles | Tosyl Compounds | Vascular Cell Adhesion Molecule-1 - genetics | Endothelial Cells - metabolism | RNA, Messenger - genetics | Androgen Antagonists - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Endothelial Cells - immunology | Receptors, Androgen - immunology | Tumor Necrosis Factor-alpha - pharmacology | Intercellular Adhesion Molecule-1 - genetics | Anilides - pharmacology | Lipopolysaccharides - pharmacology | Cell Line, Tumor | Vascular Cell Adhesion Molecule-1 - biosynthesis | Platelet Endothelial Cell Adhesion Molecule-1 - biosynthesis | Endothelial Cells - drug effects | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2007, Volume 282, Issue 42, pp. 31038 - 31045
Methylglyoxal is a highly reactive dicarbonyl degradation product formed from triose phosphates during glycolysis. Methylglyoxal forms stable adducts primarily... 
DIABETIC-RETINOPATHY | ACTIVATION | ADVANCED GLYCATION | SP1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | O-GLYCOSYLATION | MICE | 3 MAJOR PATHWAYS | EXPRESSION | HYPERGLYCEMIC DAMAGE | GLYOXALASE-I | Tumor Necrosis Factor-alpha - metabolism | Transcription, Genetic - drug effects | Kidney - pathology | Sweetening Agents - metabolism | Angiopoietin-2 - genetics | Protein Processing, Post-Translational - genetics | Diabetes Mellitus, Experimental - genetics | N-Acetylglucosaminyltransferases - genetics | Glycolysis - drug effects | Acetylglucosamine - metabolism | Glycolysis - genetics | Pyruvaldehyde - metabolism | Kidney - metabolism | Diabetic Angiopathies - pathology | Protein Processing, Post-Translational - drug effects | Arginine - genetics | Intercellular Adhesion Molecule-1 - biosynthesis | Vascular Cell Adhesion Molecule-1 - genetics | Response Elements - genetics | Diabetes Mellitus, Experimental - metabolism | Diabetic Angiopathies - genetics | Repressor Proteins - metabolism | Sp3 Transcription Factor - metabolism | Diabetic Angiopathies - metabolism | Sweetening Agents - pharmacology | Endothelial Cells - metabolism | Gene Expression Regulation - genetics | Sp3 Transcription Factor - genetics | Angiopoietin-2 - biosynthesis | Repressor Proteins - genetics | Glucose - pharmacology | Acetylglucosamine - genetics | N-Acetylglucosaminyltransferases - metabolism | Gene Expression Regulation - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Animals | Intercellular Adhesion Molecule-1 - genetics | Diabetes Mellitus, Experimental - pathology | Glucose - metabolism | Vascular Cell Adhesion Molecule-1 - biosynthesis | Mice | Endothelial Cells - pathology | Arginine - metabolism | Cell Line, Transformed | Index Medicus
Journal Article