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Nature cell biology, ISSN 1476-4679, 2011, Volume 13, Issue 10, pp. 1202 - 1213
Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch signalling, whereas vascular endothelial growth factor receptor (VEGFR... 
LYMPHATIC ENDOTHELIUM | KINASE-ACTIVITY | VASCULAR NETWORK FORMATION | ENDOTHELIAL-GROWTH-FACTOR | FACTOR-C | MOUSE EMBRYOS | EXTRACELLULAR-MATRIX | MONOCLONAL-ANTIBODY | TUMOR ANGIOGENESIS | FACTOR RECEPTOR-3 | CELL BIOLOGY | Neovascularization, Physiologic - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Receptors, Notch - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Receptors, Notch - antagonists & inhibitors | Transfection | RNA Interference | Time Factors | Forkhead Transcription Factors - metabolism | Vascular Endothelial Growth Factor D - genetics | Phosphatidylinositol 3-Kinase - metabolism | Vascular Endothelial Growth Factor Receptor-3 - deficiency | Transduction, Genetic | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Rhombencephalon - blood supply | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Forkhead Transcription Factors - genetics | Vascular Endothelial Growth Factor C - genetics | Mice, Knockout | Antibodies - pharmacology | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Signal Transduction - drug effects | Vascular Endothelial Growth Factor B - metabolism | Vascular Endothelial Growth Factor C - metabolism | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Vascular Endothelial Growth Factor B - genetics | Mice | Neovascularization, Pathologic - metabolism | Protein Kinase Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial Cells - drug effects | Physiological aspects | Blood vessels | Cellular signal transduction | Growth factor receptors | Research | Vascular endothelial growth factor
Journal Article
Angiogenesis (London), ISSN 1573-7209, 2012, Volume 15, Issue 2, pp. 171 - 185
...ORIGINAL PAPER Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab Nicholas... 
Biomedicine | Age-related macular degeneration | Cancer Research | Oncology | Affinity | Ophthalmology | VEGF receptor | Cardiology | Aflibercept | Placental growth factor | Biomedicine general | Cell Biology | ANGIOGENESIS | EFFICACY | MACULAR DEGENERATION | PHASE-II | ANTIBODY | FACTOR THERAPY | EYE | IN-VITRO | PEGAPTANIB | RETINAL DISEASES | PERIPHERAL VASCULAR DISEASE | Angiogenesis Inhibitors - immunology | Receptors, Vascular Endothelial Growth Factor | Vascular Endothelial Growth Factor B - antagonists & inhibitors | Recombinant Fusion Proteins - pharmacology | Endothelial Cells - metabolism | Humans | Angiogenesis Inhibitors - pharmacology | Vascular Endothelial Growth Factor B - immunology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor A - immunology | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor Receptor-2 - immunology | Enzyme Activation - drug effects | Bevacizumab | Endothelial Cells - immunology | Vascular Endothelial Growth Factor B - metabolism | Antibodies, Monoclonal, Humanized - pharmacology | HEK293 Cells | Ranibizumab | Vascular Endothelial Growth Factor Receptor-1 - immunology | Antibodies, Monoclonal, Humanized - immunology | Original Paper
Journal Article
Journal Article
Journal of biochemistry (Tokyo), ISSN 0021-924X, 2012, Volume 153, Issue 1, pp. 13 - 19
Vascular endothelial growth factors (VEGFs) belong to the platelet-derived growth factor supergene family, and they play central roles in the regulation of angiogenesis and lymphangiogenesis... 
VEGFR | hypoxia | preeclampsia | VEGF | tumor angiogenesis | SUPPRESSES TUMOR-GROWTH | CELLS | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-MARROW | VEGF RECEPTOR-1 | BEVACIZUMAB PLUS IRINOTECAN | NUTRIENT STARVATION | DNA-SYNTHESIS | FLT-1 | IN-VIVO | Neoplasms - metabolism | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Humans | Male | Neoplasm Proteins - antagonists & inhibitors | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | Vascular Endothelial Growth Factor A - chemistry | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Angiogenesis Inhibitors - therapeutic use | Female | Pre-Eclampsia - metabolism | Lymphangiogenesis | Angiogenesis Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Neoplasm Proteins - chemistry | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - chemistry | Neoplasms - drug therapy | Pregnancy | Vascular Endothelial Growth Factor Receptor-2 - chemistry | Animals | Pre-Eclampsia - drug therapy | Signal Transduction - drug effects | Neovascularization, Pathologic - drug therapy | Neovascularization, Pathologic - metabolism | Neovascularization, Physiologic | JB Reviews
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2001, Volume 276, Issue 10, pp. 7614 - 7620
Vascular endothelial growth factor (VEGF) induces adhesion molecules on endothelial cells during inflammation... 
PROTEIN-KINASE-C | IN-VITRO | PHOSPHORYLATION | PATHWAY | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | INHIBITOR | FLT-1 | BINDING | Vascular Endothelial Growth Factor A | Vascular Endothelial Growth Factors | Humans | Nitric Oxide Synthase - antagonists & inhibitors | NF-kappa B - metabolism | RNA, Messenger - metabolism | MAP Kinase Kinase 2 | Type C Phospholipases - antagonists & inhibitors | MAP Kinase Kinase 1 | Ribonucleases - metabolism | Flow Cytometry | Time Factors | Intercellular Adhesion Molecule-1 - biosynthesis | E-Selectin - biosynthesis | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Lymphokines - biosynthesis | Umbilical Veins - cytology | Protein Structure, Tertiary | Recombinant Proteins - metabolism | NF-kappa B - antagonists & inhibitors | Signal Transduction | Cells, Cultured | Enzyme Inhibitors - pharmacology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Endothelial Growth Factors - biosynthesis | Protein Kinase C - antagonists & inhibitors | Cell Adhesion | Blotting, Western | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Androstadienes - pharmacology | Endothelium, Vascular - metabolism | Models, Biological | Vascular Cell Adhesion Molecule-1 - biosynthesis | Nitric Oxide Synthase - metabolism | Enzyme Activation | DNA, Complementary - metabolism | Leukocytes - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Cancer cell, ISSN 1535-6108, 2008, Volume 14, Issue 5, pp. 382 - 393
A key step in angiogenesis is the upregulation of growth factor receptors on endothelial cells... 
CELLCYCLE | THERAPY | ONCOLOGY | VASCULAR INTEGRITY | IN-VIVO | GENE-EXPRESSION | DEGRADATION | TARGETS | OCULAR NEOVASCULARIZATION | TUMOR ANGIOGENESIS | MICRORNAS | CANCER | CELL BIOLOGY | Endothelium, Vascular - cytology | Luciferases - metabolism | MicroRNAs - antagonists & inhibitors | Humans | Neovascularization, Pathologic | Molecular Sequence Data | MicroRNAs - metabolism | Brain Neoplasms - blood supply | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | Brain Neoplasms - metabolism | Glioma - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Kidney - metabolism | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Oligonucleotides - pharmacology | Base Sequence | RNA, Messenger - antagonists & inhibitors | Glioma - therapy | Umbilical Veins - cytology | Receptor, Platelet-Derived Growth Factor beta - metabolism | Signal Transduction | Endosomal Sorting Complexes Required for Transport | RNA, Messenger - genetics | RNA, Small Interfering - pharmacology | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Kidney - cytology | Phosphoproteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sequence Homology, Nucleic Acid | Blotting, Western | Hepatocyte Growth Factor - metabolism | Glioma - blood supply | Xenograft Model Antitumor Assays | Magnetic Resonance Imaging | Animals | Endothelium, Vascular - metabolism | Brain Neoplasms - therapy | Fluorescent Antibody Technique | Mice | MicroRNAs - genetics | Cell Movement | Umbilical Veins - metabolism | Tyrosine | Medical colleges | Neurosciences | Messenger RNA | Gliomas | Oncology, Experimental | Brain tumors | Research | Growth factors | Cancer | Endothelium | PDGFR | VEGFR | miRNA | cancer | HGS | angiogenesis
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2011, Volume 286, Issue 50, pp. 42863 - 42872
Background: Several studies have suggested that decreasing VEGF levels might result in placental oxidative stress in preeclampsia. Results: VEGF activates Nrf2... 
SIGNAL-TRANSDUCTION | MEDIATED DAMAGE | CELLS | OXIDATIVE STRESS | ACTIVATION | ANTIOXIDANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLACENTA | GENE-EXPRESSION | RECEPTOR | PREGNANCY | Pre-Eclampsia - genetics | Nitriles - pharmacology | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Immunoblotting | Female | NF-E2-Related Factor 2 - genetics | Flavonoids - pharmacology | Pre-Eclampsia - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Vascular Endothelial Growth Factor A - pharmacology | Cell Survival - drug effects | MAP Kinase Kinase 1 - antagonists & inhibitors | Butadienes - pharmacology | Enzyme-Linked Immunosorbent Assay | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | MAP Kinase Kinase 1 - metabolism | Imidazoles - pharmacology | MAP Kinase Kinase 2 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Pregnancy | Mitogen-Activated Protein Kinase 3 - metabolism | MAP Kinase Kinase 2 - antagonists & inhibitors | NF-E2-Related Factor 2 - metabolism | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cell Line, Tumor | Pyridines - pharmacology | Oxidative Stress - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | Molecular Bases of Disease | Vascular Endothelial Growth Factor (VEGF) | Oxidative Stress | Carbon Monoxide | Nrf2 | Preeclampsia | Heme Oxygenase
Journal Article
Journal Article
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 03/2018, Volume 197, Issue 6, pp. 703 - 704
Journal Article