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Nature cell biology, ISSN 1476-4679, 2011, Volume 13, Issue 10, pp. 1202 - 1213
Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch signalling, whereas vascular endothelial growth factor receptor (VEGFR... 
LYMPHATIC ENDOTHELIUM | KINASE-ACTIVITY | VASCULAR NETWORK FORMATION | ENDOTHELIAL-GROWTH-FACTOR | FACTOR-C | MOUSE EMBRYOS | EXTRACELLULAR-MATRIX | MONOCLONAL-ANTIBODY | TUMOR ANGIOGENESIS | FACTOR RECEPTOR-3 | CELL BIOLOGY | Neovascularization, Physiologic - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Receptors, Notch - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Receptors, Notch - antagonists & inhibitors | Transfection | RNA Interference | Time Factors | Forkhead Transcription Factors - metabolism | Vascular Endothelial Growth Factor D - genetics | Phosphatidylinositol 3-Kinase - metabolism | Vascular Endothelial Growth Factor Receptor-3 - deficiency | Transduction, Genetic | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Rhombencephalon - blood supply | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Forkhead Transcription Factors - genetics | Vascular Endothelial Growth Factor C - genetics | Mice, Knockout | Antibodies - pharmacology | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Signal Transduction - drug effects | Vascular Endothelial Growth Factor B - metabolism | Vascular Endothelial Growth Factor C - metabolism | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Vascular Endothelial Growth Factor B - genetics | Mice | Neovascularization, Pathologic - metabolism | Protein Kinase Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial Cells - drug effects | Physiological aspects | Blood vessels | Cellular signal transduction | Growth factor receptors | Research | Vascular endothelial growth factor
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2010, Volume 107, Issue 6, pp. 2425 - 2430
Vascular endothelial growth factors (VEGFs) regulate blood and lymph vessel formation through activation of three receptor tyrosine kinases, VEGFR-1, -2, and -3... 
Proteins | Angiogenesis | Receptors | Vascular endothelial growth factors | Endothelial growth factors | Ligands | Dimers | Chimeras | Monomers | Crystal structure | Vascular endothelial growth factor receptor-2 | Lymphangiogenesis | Vascular endothelial growth factor C | ACTIVATION | COMPLEX | FACTOR-C | angiogenesis | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ORF-VIRUS | TYROSINE KINASES | vascular endothelial growth factor receptor-2 | VASCULAR-PERMEABILITY | FAMILY-MEMBER | lymphangiogenesis | KINASE DOMAIN RECEPTOR | vascular endothelial growth factor C | Humans | Crystallography, X-Ray | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Recombinant Fusion Proteins - metabolism | Spodoptera | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor A - chemistry | Vascular Endothelial Growth Factor C - chemistry | Vascular Endothelial Growth Factor Receptor-1 - genetics | Protein Structure, Tertiary | Cell Line | Cell Survival | Models, Molecular | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Binding Sites - genetics | Recombinant Fusion Proteins - chemistry | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - chemistry | Vascular Endothelial Growth Factor C - genetics | Vascular Endothelial Growth Factor Receptor-3 - chemistry | Vascular Endothelial Growth Factor Receptor-2 - chemistry | Animals | Hydrogen Bonding | Vascular Endothelial Growth Factor C - metabolism | Protein Binding | Recombinant Fusion Proteins - genetics | Protein Conformation | Kinetics | Mutation | Vascular Endothelial Growth Factor Receptor-3 - genetics | Development and progression | Research | Growth factor receptors | Neovascularization | Properties | Vascular endothelial growth factor | Protein binding | Lymphangioma | Biological Sciences
Journal Article
International journal of molecular sciences, ISSN 1661-6596, 09/2018, Volume 19, Issue 9, p. 2487
.... Signaling via vascular endothelial growth factor (VEGF)-C, VEGF-D, and VEGF receptor (VEGFR)-3 is a central molecular mechanism for lymphangiogenesis... 
Vascular endothelial growth factor-C | Lymphangiogenesis | Transforming growth factor-β | Fibrosis | TISSUE-GROWTH-FACTOR | TYPE-1 DIABETIC-PATIENTS | PERITONEAL MESOTHELIAL CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | vascular endothelial growth factor-C | MONOCLONAL-ANTIBODY | FACTOR RECEPTOR-3 | CHEMISTRY, MULTIDISCIPLINARY | SOLUTE TRANSPORT | transforming growth factor-beta | LYMPHATIC ABSORPTION RATE | ULTRAFILTRATION FAILURE | DIALYSIS PATIENTS | lymphangiogenesis | fibrosis | GLYCATION END-PRODUCTS | Epithelial Cells - metabolism | Humans | Peritoneal Fibrosis - genetics | Nephrogenic Fibrosing Dermopathy - metabolism | Renal Insufficiency, Chronic - metabolism | Lymphatic Vessels - metabolism | Peritoneal Fibrosis - metabolism | Renal Insufficiency, Chronic - genetics | Vascular Endothelial Growth Factor D - genetics | Macrophages - pathology | Signal Transduction | Gene Expression Regulation | Nephrogenic Fibrosing Dermopathy - genetics | Epithelial Cells - pathology | Nephrogenic Fibrosing Dermopathy - pathology | Peritoneal Fibrosis - pathology | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Vascular Endothelial Growth Factor C - genetics | Renal Insufficiency, Chronic - pathology | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Transforming Growth Factor beta - genetics | Vascular Endothelial Growth Factor C - metabolism | Lymphatic Vessels - pathology | Connective Tissue Growth Factor - genetics | Lymphangiogenesis - genetics | Transforming Growth Factor beta - metabolism | Connective Tissue Growth Factor - metabolism | Vascular Endothelial Growth Factor Receptor-3 - genetics | Lymphatic system | Epithelial cells | Transforming growth factor-a | Blood vessels | Connective tissue growth factor | Macrophages | Endothelial cells | Peritoneal dialysis | Vascular endothelial growth factor receptors | Connective tissues | Signal transduction | Signaling | Etiology | Capillaries | Vascular endothelial growth factor | Growth factors | Peritoneum | Nephrology | Homeostasis | Mitochondrial DNA | Proteins | Fibroblasts | Cytokines | Inflammation | Permeability | Diabetes | Kidney diseases | transforming growth factor-β
Journal Article
Annals of the New York Academy of Sciences, ISSN 1749-6632, 05/2008, Volume 1131, Issue 1, pp. 225 - 234
.... These include the secreted glycoproteins vascular endothelial growth factor-C (VEGF-C) and VEGF-D, which act via their cognate receptor tyrosine kinase VEGF receptor-3 (VEGFR-3... 
lymphangiogenesis | lymphatic vessel | cancer | angiogenesis | lymph node | Angiogenesis | Lymph node | Lymphangiogenesis | Lymphatic vessel | Cancer | INTRATUMORAL LYMPHANGIOGENESIS | ENDOTHELIAL-GROWTH-FACTOR | FACTOR-C EXPRESSION | MULTIDISCIPLINARY SCIENCES | TUMOR LYMPHANGIOGENESIS | VEGF-C | FACTOR RECEPTOR-3 | MELANOMA METASTASIS | BREAST-CANCER | NODE METASTASIS | PROGNOSTIC-FACTOR | Lymph Nodes - pathology | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor Receptor-2 - immunology | Vascular Endothelial Growth Factor A - genetics | Neovascularization, Pathologic - pathology | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Lymph Nodes - blood supply | Lymphatic Metastasis - pathology | Neovascularization, Pathologic - prevention & control | Vascular Endothelial Growth Factor D - genetics | Signal Transduction | Lymphangiogenesis - physiology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Vascular Endothelial Growth Factor C - genetics | Vascular Endothelial Growth Factor D - metabolism | Animals | Lymphatic Metastasis - prevention & control | Models, Biological | Vascular Endothelial Growth Factor C - metabolism | Lymphatic Vessels - pathology | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial growth factors | Metastasis
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2010, Volume 464, Issue 7290, pp. 917 - 921
The vascular endothelial growth factors (VEGFs) are major angiogenic regulators and are involved in several aspects of endothelial cell physiology(1... 
TRANSPORT | LACKING | LIPID-METABOLISM | ANGIOGENESIS | PERMEABILITY | LETHALITY | MULTIDISCIPLINARY SCIENCES | MOUSE | FLT-1 | VEGF-B | RECEPTOR-1 | Neuropilin-1 - genetics | Vascular Endothelial Growth Factor B - deficiency | Oligonucleotide Array Sequence Analysis | Neuropilin-1 - metabolism | Humans | Adipose Tissue, White - metabolism | Male | Mitochondrial Proteins - genetics | Biological Transport | Mitochondria - genetics | Mitochondrial Proteins - metabolism | Myocardium - metabolism | Transcription, Genetic | Muscles - metabolism | Fatty Acids - metabolism | Cell Line | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Mitochondria - metabolism | Organ Specificity | Endothelium - cytology | Animals | Cell Nucleus - genetics | Endothelium - metabolism | Vascular Endothelial Growth Factor B - metabolism | Vascular Endothelial Growth Factor B - genetics | Adipose Tissue, Brown - metabolism | Mice | Fatty Acid Transport Proteins - genetics | Care and treatment | Physiological aspects | Genetic aspects | Diabetes | Research | Cardiovascular diseases | Vascular endothelial growth factor | Proteins | Signal transduction | Rodents | Binding sites | Genetik | Biokemi och molekylärbiologi | Cell and Molecular Biology | Biochemistry and Molecular Biology | Genetics | Cellbiologi | Cell- och molekylärbiologi | Cell Biology
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 04/2006, Volume 130, Issue 4, pp. 1270 - 1282
Background & Aims: Vascular endothelial growth factor (VEGF) is secreted by several epithelia and modulates cellular functions by autocrine and paracrine mechanisms... 
PARTIAL-HEPATECTOMY | DUCTAL SECRETION | CHOLANGIOCARCINOMA GROWTH | BILIARY TREE | MESSENGER-RNA | CELL HYPERPLASIA | VEGF | KINASE-C-ALPHA | BDL RATS | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Phosphorylation | Protein Kinase C-alpha - metabolism | Bile Ducts - metabolism | Calcium - metabolism | Rats, Inbred F344 | Male | Vascular Endothelial Growth Factor A - metabolism | Bile Ducts - cytology | Vascular Endothelial Growth Factor A - secretion | Ligation | src-Family Kinases - metabolism | Hepatocytes - secretion | Vascular Endothelial Growth Factor A - pharmacology | Bile Ducts - secretion | Autocrine Communication - physiology | Cells, Cultured | Vascular Endothelial Growth Factor A - blood | Rats | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor A - immunology | Recombinant Proteins - pharmacology | Vascular Endothelial Growth Factor C - immunology | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Antibodies - pharmacology | Animals | Vascular Endothelial Growth Factor C - metabolism | Cell Proliferation - drug effects | Inositol 1,4,5-Trisphosphate - metabolism | Vascular Endothelial Growth Factor A - physiology | Mitogen-Activated Protein Kinases - metabolism | Vascular Endothelial Growth Factor C - pharmacology | Phosphates | Antigens | Medical colleges | Inositol | Antibodies | Serum albumin | Monosaccharides | Viral antibodies | Messenger RNA | Transglutaminases | Protein kinases | Vascular endothelial growth factor | Sugars
Journal Article
Human Pathology, ISSN 0046-8177, 2013, Volume 44, Issue 10, pp. 2204 - 2212
Summary Vascular endothelial growth factor (VEGF) promotes growth of blood or lymphatic vessels... 
Pathology | VEGF-C | Undifferentiated carcinoma | VEGF-A | Papillary thyroid carcinoma | ANGIOGENESIS | PATHOLOGY | CANCER | FEATURES | LYMPH-NODE METASTASES | MUTATION | LYMPHANGIOGENESIS | FOLLICULAR VARIANT | INHIBITORS | EXPRESSION | Lymph Nodes - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Adenocarcinoma, Follicular - genetics | Male | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Neovascularization, Pathologic - pathology | Adenocarcinoma, Follicular - secondary | Biomarkers, Tumor - metabolism | Adult | Female | Adenocarcinoma, Follicular - metabolism | Carcinoma - secondary | Lymph Nodes - metabolism | Lymphatic Metastasis | Reverse Transcriptase Polymerase Chain Reaction | Vascular Endothelial Growth Factor C - genetics | Thyroid Cancer, Papillary | Thyroid Neoplasms - genetics | Carcinoma, Papillary | Vascular Endothelial Growth Factor C - metabolism | Thyroid Neoplasms - secondary | Carcinoma - genetics | Neovascularization, Pathologic - genetics | Biomarkers, Tumor - genetics | Neovascularization, Pathologic - metabolism | Carcinoma - metabolism | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Immunohistochemistry | Thyroid cancer | Carcinoma | RNA | Development and progression | Neovascularization | Vascular endothelial growth factor | Cancer | Proteins | Polymerase chain reaction | Thermal cycling | Polyclonal antibodies
Journal Article