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Clinical Cancer Research, ISSN 1078-0432, 11/2006, Volume 12, Issue 21, pp. 6573 - 6584
Journal Article
Journal of Biochemistry, ISSN 0021-924X, 01/2013, Volume 153, Issue 1, pp. 13 - 19
Vascular endothelial growth factors (VEGFs) belong to the platelet-derived growth factor supergene family, and they play central roles in the regulation of... 
VEGFR | hypoxia | preeclampsia | VEGF | tumor angiogenesis | SUPPRESSES TUMOR-GROWTH | CELLS | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-MARROW | VEGF RECEPTOR-1 | BEVACIZUMAB PLUS IRINOTECAN | NUTRIENT STARVATION | DNA-SYNTHESIS | FLT-1 | IN-VIVO | Neoplasms - metabolism | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Humans | Male | Neoplasm Proteins - antagonists & inhibitors | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | Vascular Endothelial Growth Factor A - chemistry | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Angiogenesis Inhibitors - therapeutic use | Female | Pre-Eclampsia - metabolism | Lymphangiogenesis | Angiogenesis Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Neoplasm Proteins - chemistry | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - chemistry | Neoplasms - drug therapy | Pregnancy | Vascular Endothelial Growth Factor Receptor-2 - chemistry | Animals | Pre-Eclampsia - drug therapy | Signal Transduction - drug effects | Neovascularization, Pathologic - drug therapy | Neovascularization, Pathologic - metabolism | Neovascularization, Physiologic | JB Reviews
Journal Article
Cell Metabolism, ISSN 1550-4131, 01/2014, Volume 19, Issue 1, pp. 37 - 48
Journal Article
Nature, ISSN 0028-0836, 12/2005, Volume 438, Issue 7069, pp. 820 - 827
Journal Article
eLife, ISSN 2050-084X, 06/2013, Volume 2013, Issue 2, p. e00324
Optimal phototransduction requires separation of the avascular photoreceptor layer from the adjacent vascularized inner retina and choroid. Breakdown of... 
LONG-TERM EVALUATION | OPTICAL COHERENCE TOMOGRAPHY | SUBRETINAL NEOVASCULARIZATION | TYROSINE KINASE | BIOLOGY | MACULAR DEGENERATION | GENE-THERAPY | CHOROIDAL NEOVASCULARIZATION | ENDOTHELIAL GROWTH-FACTOR | RETINAL-PIGMENT EPITHELIUM | TRANSGENIC MICE | Retinal Pigment Epithelium - metabolism | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Humans | Male | Retinal Neovascularization - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Case-Control Studies | Retinal Pigment Epithelium - pathology | Choroidal Neovascularization - pathology | RNA Interference | Aged, 80 and over | Adult | Female | Retinal Neovascularization - genetics | Disease Models, Animal | Vascular Endothelial Growth Factor Receptor-1 - genetics | Vascular Endothelial Growth Factor Receptor-1 - deficiency | Signal Transduction | Down-Regulation | Mice, Inbred C57BL | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Mice, Knockout | Antibodies - pharmacology | Macular Degeneration - metabolism | Animals | Choroidal Neovascularization - metabolism | Macular Degeneration - genetics | Vision, Ocular | Aged | Mice, Inbred BALB C | Photoreceptor Cells, Vertebrate - metabolism | Choroidal Neovascularization - genetics | Photoreceptor Cells, Vertebrate - pathology | Retinal Neovascularization - pathology | Macular Degeneration - pathology | RNA viruses | Animal models | Laboratories | RNA-mediated interference | Retina | Epithelium | Retinal pigment epithelium | Vascularization | Macular degeneration | Medicine | Proteins | Signal transduction | Phototransduction | Blindness | Photoreceptors | Females | Vascular endothelial growth factor | Age
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 03/2010, Volume 14, Issue 3, pp. 528 - 552
•  Introduction ‐  Angiogenesis in physiology and pathology ‐  Angiogenesis in current medicine ‐  VEGF ligand and receptor system: where does sVEGFR1 fit? ‐ ... 
multi‐scale modelling | molecular systems biology | angiogenesis | neovascularization | computational modelling | vascular endothelial growth factor (VEGF) | systems pharmacology | soluble fms‐like tyrosine kinase 1 (sFlt‐1) | Angiogenesis | Soluble fms-like tyrosine kinase 1 (sFlt-1) | Vascular endothelial growth factor (VEGF) | Computational modelling | Multi-scale modelling | Molecular systems biology | Neovascularization | Systems pharmacology | FLT-1 GENE-THERAPY | MEDICINE, RESEARCH & EXPERIMENTAL | soluble fms-like tyrosine kinase 1 (sFlt-1) | COLLAGEN-INDUCED ARTHRITIS | ENDOTHELIAL-GROWTH-FACTOR | CARDIOVASCULAR MEDICINE | ANGIOGENIC FACTORS | CELL BIOLOGY | SKELETAL-MUSCLE | SOLUBLE VEGF RECEPTOR-1 | INHIBITS ANGIOGENESIS | ANTIANGIOGENIC GENE | PERIPHERAL ARTERIAL-DISEASE | multi-scale modelling | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Atherosclerosis - drug therapy | Atherosclerosis - physiopathology | Humans | Vascular Endothelial Growth Factor A - blood | Vascular Endothelial Growth Factor Receptor-1 - physiology | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Systems Biology | Neoplasms - drug therapy | Atherosclerosis - blood | Neoplasms - blood | Models, Biological | Angiogenesis Inhibitors - therapeutic use | Neovascularization, Pathologic - physiopathology | Neovascularization, Pathologic - prevention & control | Neoplasms - physiopathology | Vascular Endothelial Growth Factor Receptor-1 - blood | Vascular Endothelial Growth Factor A - physiology | Physiological effects | Clinical trials | Cardiovascular disease | Biology | Kinases | Cancer therapies | Proteins | Signal transduction | Heterogeneity | Receptors | Ischemia | Atherosclerosis | Eclampsia | Physiology | Capillaries | Vascular endothelial growth factor | Growth factors | Therapeutic applications | Markers | Cell membranes | Bioavailability | Permeability | Diseases | Pregnancy | Signaling | Molecular modelling | Arteriosclerosis | Computer applications | Hypoxia | Ligands | Microvasculature | Molecular biology | Protein structure | Cancer | Reviews
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2011, Volume 108, Issue 28, pp. 11590 - 11595
PlGF, one of the ligands for VEGFR-1, has been implicated in tumor angiogenesis. However, more recent studies indicate that genetic or pharmacological... 
Tumor cell line | Cell growth | Vascular endothelial growth factors | HEK293 cells | Stromal cells | Cell lines | Antibodies | Endothelial cells | Tumors | Cancer | Stroma | Angiogenesis | Tyrosine kinase | Placental growth factor | Vascular endothelial growth factor | CANCER-CELLS | ENDOTHELIAL-GROWTH-FACTOR | angiogenesis | MULTIDISCIPLINARY SCIENCES | stroma | tyrosine kinase | BONE-MARROW | FACTOR RECEPTOR-1 | HIGH-AFFINITY BINDING | FLT-1 | placental growth factor | SIGNAL-TRANSDUCTION | vascular endothelial growth factor | CARCINOMA | RNA, Small Interfering - genetics | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Neoplasms - etiology | Pregnancy Proteins - antagonists & inhibitors | Humans | Neovascularization, Pathologic | Pregnancy Proteins - pharmacology | Gene Knockdown Techniques | MAP Kinase Signaling System | Neoplasms - therapy | Female | Vascular Endothelial Growth Factor Receptor-1 - genetics | Signal Transduction | Endothelial Cells - metabolism | Stromal Cells - metabolism | Neoplasms - blood supply | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Pregnancy Proteins - immunology | Mice, Knockout | Animals | Antibodies, Monoclonal - administration & dosage | Mice, Nude | Neoplasms - immunology | Cell Line, Tumor | Placenta Growth Factor | Mice | Mice, Inbred BALB C | Endothelial Cells - drug effects | Biological Sciences
Journal Article
Cancer Research, ISSN 0008-5472, 02/2011, Volume 71, Issue 4, pp. 1474 - 1485
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2011, Volume 301, Issue 3, pp. 1043 - 1055
Spleen tyrosine kinase (Syk), expressed in endothelial cells, has been implicated in migration and proliferation and in vasculogenesis. This study was... 
Tube formation | Human umbilical vein endothelial cells | Transactivation of endothelial growth factor receptor | Aortic sprouting | EA.hy926 cells | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | SYK | RAT | aortic sprouting | transactivation of endothelial growth factor receptor | VASCULAR SMOOTH-MUSCLE | CELL HYPERTROPHY | tube formation | SIGNAL-TRANSDUCTION | IN-VITRO | human umbilical vein endothelial cells | PERIPHERAL VASCULAR DISEASE | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Neovascularization, Physiologic - drug effects | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Phosphorylation | Protein-Tyrosine Kinases - metabolism | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Vascular Endothelial Growth Factor A - metabolism | Angiotensin II Type 1 Receptor Blockers - pharmacology | Protein-Tyrosine Kinases - genetics | Receptor, Epidermal Growth Factor - metabolism | Transfection | RNA Interference | Time Factors | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Angiotensin II - metabolism | Signal Transduction | Endothelial Cells - metabolism | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Rats | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Epidermal Growth Factor - metabolism | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Rats, Sprague-Dawley | Animals | Analysis of Variance | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Endothelial Cells - drug effects | Protein-Tyrosine Kinases - antagonists & inhibitors | Angiotensin | Physiological aspects | Protein tyrosine kinase | Genetic aspects | Research | Neovascularization | Vascular endothelial growth factor | Integrative Cardiovascular Physiology and Pathophysiology
Journal Article