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Cancer Research, ISSN 0008-5472, 01/2008, Volume 68, Issue 2, pp. 521 - 529
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2010, Volume 28, Issue 5, pp. 780 - 787
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2010, Volume 107, Issue 45, pp. 19308 - 19313
Journal Article
Molecular Imaging and Biology, ISSN 1536-1632, 2/2018, Volume 20, Issue 1, pp. 85 - 93
Plaque vulnerability is associated with inflammation and angiogenesis, processes that rely on vascular endothelial growth factor (VEGF) signaling via two... 
Molecular imaging | Vascular endothelial growth factor receptor (VEGFR) | Diabetes | Medicine & Public Health | Imaging / Radiology | Atherosclerosis | CELLS | IDENTIFY | INSTABILITY | VEGF RECEPTORS | PLAQUE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Atherosclerosis - pathology | Diabetes Mellitus, Experimental - diagnosis | Apolipoproteins E - deficiency | Tomography, Emission-Computed, Single-Photon | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Atherosclerosis - complications | Male | Molecular Imaging - methods | Polyethylene Glycols - chemistry | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Apolipoproteins E - metabolism | Atherosclerosis - metabolism | Diabetes Mellitus, Experimental - blood | Tissue Distribution | Animals | Atherosclerosis - diagnosis | Diabetes Mellitus, Experimental - complications | Mice | Single-Chain Antibodies | Blood Glucose - metabolism | Diabetes Mellitus, Experimental - metabolism | Selectivity | Biology | Proteins | Angiogenesis | Receptors | Computed tomography | Apolipoprotein E | Polyethylene glycol | Imaging | Tomography | Aorta | Lesions | Vascular endothelial growth factor | Plaques | Photon emission | Medical imaging | Diabetes mellitus | Blood vessels | Software reliability | Single photon emission computed tomography | Mutants | Vascular endothelial growth factor receptors | Signaling | Computation | Arteriosclerosis | Coronary vessels | Tracers | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 05/2005, Volume 65, Issue 10, pp. 4389 - 4400
Journal Article
Experimental Cell Research, ISSN 0014-4827, 03/2014, Volume 322, Issue 1, pp. 89 - 98
Vascular endothelial growth factor (VEGF) triggers crucial signaling processes that regulate tumor angiogenesis and, therefore, represents an attractive target... 
Angiogenesis | Endothelial cell | Olive oil | Signaling pathway | VEGF/VEGFR-2 | KINASE-ACTIVITY | MEDITERRANEAN DIET | PHENOLIC-COMPOUNDS | HUMANS | TUMOR ANGIOGENESIS | CELL MIGRATION | VEGF-A | CELL BIOLOGY | SIGNAL-TRANSDUCTION | ONCOLOGY | TYROSINE RESIDUES | CANCER-RISK | Neovascularization, Physiologic - drug effects | Quercetin - analogs & derivatives | Plant Oils - pharmacology | Human Umbilical Vein Endothelial Cells - drug effects | Phenylethyl Alcohol - analogs & derivatives | Plant Extracts - pharmacology | Humans | Cells, Cultured | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Olive Oil | Down-Regulation - drug effects | Cell Movement - drug effects | Phenylethyl Alcohol - pharmacology | Human Umbilical Vein Endothelial Cells - physiology | Oleic Acid - pharmacology | Protein Processing, Post-Translational - drug effects | Quercetin - pharmacology | Cell Proliferation - drug effects | Phosphorylation - drug effects | Plant Oils - chemistry | Antioxidants | Monounsaturated fatty acids | Angiogenesis inhibitors | Vascular endothelial growth factor | Phosphorylation | Cellular biology | Cell adhesion & migration | Index Medicus | HUMAN POPULATIONS | VEINS | ANGIOGENESIS | ANTIOXIDANTS | NEOPLASMS | PHOSPHORYLATION | CATTLE | SIGNALS | COMPARATIVE EVALUATIONS | 60 APPLIED LIFE SCIENCES | GROWTH FACTORS | CAPILLARIES | OLEIC ACID | INHIBITION | DIET | PHENOLS | IN VITRO | OLIVE OIL | PLANTS | NUTRITION | RECEPTORS | FOOD
Journal Article
Nature, ISSN 0028-0836, 04/2012, Volume 484, Issue 7392, pp. 110 - 114
Developing tissues and growing tumours produce vascular endothelial growth factors (VEGFs), leading to the activation of the corresponding receptors in... 
TIP CELL-FORMATION | DLL4 | PATHWAYS | ACTIVATION | BEVACIZUMAB | MULTIDISCIPLINARY SCIENCES | GROWTH | MOUSE | LIGAND | INHIBIT | D114 | Human Umbilical Vein Endothelial Cells | Neovascularization, Physiologic - drug effects | Up-Regulation | Vascular Endothelial Growth Factor Receptor-3 - biosynthesis | Receptors, Notch - metabolism | Humans | Male | Intracellular Signaling Peptides and Proteins - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Intracellular Signaling Peptides and Proteins - deficiency | Membrane Proteins - deficiency | Receptors, Notch - antagonists & inhibitors | HEK293 Cells | Female | Transcription, Genetic | Membrane Proteins - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Endothelial Cells - metabolism | Membrane Proteins - genetics | Vascular Endothelial Growth Factor Receptor-2 - deficiency | Cells, Cultured | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Neovascularization, Physiologic - physiology | Animals | Signal Transduction - drug effects | Endothelial Cells - cytology | Models, Biological | Mice | Protein Kinase Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial Cells - drug effects | Cellular control mechanisms | Physiological aspects | Growth factor receptors | Neovascularization | Research | Vascular endothelial growth factor | Endothelium | Angiogenesis | Ligands | Kinases | Rodents | Index Medicus
Journal Article
Angiogenesis, ISSN 0969-6970, 6/2012, Volume 15, Issue 2, pp. 171 - 185
Pharmacological inhibition of VEGF-A has proven to be effective in inhibiting angiogenesis and vascular leak associated with cancers and various eye diseases.... 
Biomedicine | Age-related macular degeneration | Cancer Research | Oncology | Affinity | Ophthalmology | VEGF receptor | Cardiology | Aflibercept | Placental growth factor | Biomedicine general | Cell Biology | ANGIOGENESIS | EFFICACY | MACULAR DEGENERATION | PHASE-II | ANTIBODY | FACTOR THERAPY | EYE | IN-VITRO | PEGAPTANIB | RETINAL DISEASES | PERIPHERAL VASCULAR DISEASE | Angiogenesis Inhibitors - immunology | Receptors, Vascular Endothelial Growth Factor | Vascular Endothelial Growth Factor B - antagonists & inhibitors | Recombinant Fusion Proteins - pharmacology | Endothelial Cells - metabolism | Humans | Angiogenesis Inhibitors - pharmacology | Vascular Endothelial Growth Factor B - immunology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor A - immunology | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor Receptor-2 - immunology | Enzyme Activation - drug effects | Bevacizumab | Endothelial Cells - immunology | Vascular Endothelial Growth Factor B - metabolism | Antibodies, Monoclonal, Humanized - pharmacology | HEK293 Cells | Ranibizumab | Vascular Endothelial Growth Factor Receptor-1 - immunology | Antibodies, Monoclonal, Humanized - immunology | Index Medicus | Original Paper
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2011, Volume 44, Issue 4, pp. 545 - 558
Journal Article
Oncogene, ISSN 0950-9232, 11/2017, Volume 36, Issue 47, pp. 6531 - 6541
Vascular endothelial growth factor receptor-2 (VEGFR2) is the main pro-angiogenic receptor expressed by endothelial cells (ECs). Using surface plasmon... 
CELL ADHESION | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCOSYLATION | PROTEOGLYCAN | ALPHA(V)BETA INTEGRIN | CELL BIOLOGY | CHORIOALLANTOIC MEMBRANE | ONCOLOGY | GENETICS & HEREDITY | SURFACE | LECTIN HISTOCHEMISTRY | SIALIC ACIDS | EXPRESSION | Human Umbilical Vein Endothelial Cells | Surface Plasmon Resonance | Humans | Ribosome Inactivating Proteins - pharmacology | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Female | Phosphorylation - drug effects | Galactosides | Endothelial Cells - metabolism | Down-Regulation | Mice, Inbred C57BL | Cells, Cultured | Sialyltransferases - genetics | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Plant Lectins - pharmacology | Sialyltransferases - metabolism | Chick Embryo | N-Acetylneuraminic Acid - metabolism | Cell Movement - drug effects | Animals | Fluorescent Antibody Technique | Cell Proliferation - drug effects | Mice | Neovascularization, Pathologic - metabolism | Protein Processing, Post-Translational | RNA, Small Interfering | Chorioallantoic Membrane | Neovascularization, Physiologic | Embryo | Usage | Lectins | Fluorescent antibody technique | Research | Neovascularization | Immunofluorescence | Vascular endothelial growth factor | Animal models | Immunoprecipitation | Ribonucleic acid--RNA | Endothelial cells | Vascular endothelial growth factor receptors | Vascularization | Angiogenesis | Chorioallantoic membrane | Surface plasmon resonance | Sugar | Fucose | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2010, Volume 107, Issue 6, pp. 2425 - 2430
Vascular endothelial growth factors (VEGFs) regulate blood and lymph vessel formation through activation of three receptor tyrosine kinases, VEGFR-1, -2, and... 
Proteins | Angiogenesis | Receptors | Vascular endothelial growth factors | Endothelial growth factors | Ligands | Dimers | Chimeras | Monomers | Crystal structure | Vascular endothelial growth factor receptor-2 | Lymphangiogenesis | Vascular endothelial growth factor C | ACTIVATION | COMPLEX | FACTOR-C | angiogenesis | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ORF-VIRUS | TYROSINE KINASES | vascular endothelial growth factor receptor-2 | VASCULAR-PERMEABILITY | FAMILY-MEMBER | lymphangiogenesis | KINASE DOMAIN RECEPTOR | vascular endothelial growth factor C | Humans | Crystallography, X-Ray | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Recombinant Fusion Proteins - metabolism | Spodoptera | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor A - chemistry | Vascular Endothelial Growth Factor C - chemistry | Vascular Endothelial Growth Factor Receptor-1 - genetics | Protein Structure, Tertiary | Cell Line | Cell Survival | Models, Molecular | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Binding Sites - genetics | Recombinant Fusion Proteins - chemistry | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - chemistry | Vascular Endothelial Growth Factor C - genetics | Vascular Endothelial Growth Factor Receptor-3 - chemistry | Vascular Endothelial Growth Factor Receptor-2 - chemistry | Animals | Hydrogen Bonding | Vascular Endothelial Growth Factor C - metabolism | Protein Binding | Recombinant Fusion Proteins - genetics | Protein Conformation | Kinetics | Mutation | Vascular Endothelial Growth Factor Receptor-3 - genetics | Development and progression | Research | Growth factor receptors | Neovascularization | Properties | Vascular endothelial growth factor | Protein binding | Lymphangioma | Signal transduction | Immunoglobulins | Membranes | Biochemistry | Kinases | Binding sites | Index Medicus | Biological Sciences
Journal Article