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Diabetes, Obesity and Metabolism, ISSN 1462-8902, 12/2015, Volume 17, Issue 12, pp. 1180 - 1193
Aims: To determine the effects of empagliflozin on blood pressure (BP) and markers of arterial stiffness and vascular resistance in patients with type 2... 
phase | cardiovascular disease | study | type 2 diabetes | inhibitor | SGLT2 | III | Phase III study | Type 2 diabetes | Cardiovascular disease | SGLT2 inhibitor | METFORMIN | ADD-ON | CARDIOVASCULAR EVENTS | RISK | MELLITUS | PULSE PRESSURE | ALL-CAUSE MORTALITY | GLUCOSE | phase III study | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | HEART-RATE | Benzhydryl Compounds - administration & dosage | Humans | Middle Aged | Male | Risk | Dose-Response Relationship, Drug | Heart Rate - drug effects | Benzhydryl Compounds - adverse effects | Hypoglycemic Agents - administration & dosage | Arteriosclerosis - epidemiology | Hypertension - prevention & control | Vascular Resistance - drug effects | Female | Glucosides - therapeutic use | Blood Pressure - drug effects | Diabetic Angiopathies - prevention & control | Benzhydryl Compounds - therapeutic use | Diabetes Mellitus, Type 2 - complications | Glucosides - adverse effects | Hypoglycemic Agents - therapeutic use | Arteriosclerosis - complications | Arteriosclerosis - prevention & control | Glucosides - administration & dosage | Vascular Stiffness - drug effects | Biomarkers | Hypertension - complications | Diabetic Angiopathies - epidemiology | Aged | Blood Pressure Monitoring, Ambulatory | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Cohort Studies | Hypertension | Care and treatment | Blood pressure | Heart beat | Index Medicus | Original
Journal Article
Circulation, ISSN 0009-7322, 06/2014, Volume 129, Issue 23, pp. 2403 - 2413
BACKGROUND—Glycosphingolipids, integral components of the cell membrane, have been shown to serve as messengers, transducing growth factor–initiated... 
Molecular imaging | Mice | Glycosphingolipids | Knockout | Atherosclerosis | atherosclerosis | CARDIAC & CARDIOVASCULAR SYSTEMS | GLUCOSYLCERAMIDE SYNTHASE | SERUM | molecular imaging | GENE KNOCKOUT MICE | mice, knockout | INSULIN SENSITIVITY | ADHESION | METABOLISM | glycosphingolipids | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | EXPRESSION | DENSITY-LIPOPROTEIN RECEPTOR | Hyperlipidemias - genetics | Calcium - metabolism | Male | Aorta - metabolism | Antigens, CD - metabolism | Dose-Response Relationship, Drug | Pulsatile Flow - drug effects | Cholesterol, Dietary - pharmacology | Diet, High-Fat | Ultrasonography | Lipoproteins, LDL - metabolism | Rabbits | Aorta - diagnostic imaging | Hyperlipidemias - metabolism | Models, Cardiovascular | Aorta - drug effects | Coronary Artery Disease - metabolism | Glycosphingolipids - biosynthesis | Hyperlipidemias - drug therapy | Enzyme Inhibitors - pharmacology | Lactosylceramides - metabolism | Morpholines - pharmacology | Coronary Artery Disease - drug therapy | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Apolipoproteins E - genetics | Vascular Stiffness - drug effects | Coronary Artery Disease - genetics | Glycosphingolipids - metabolism | Glucosylceramides - metabolism | Animal experimentation | Usage | Physiological aspects | Research | Apolipoproteins | Cholesterol | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal Article
Hypertension, ISSN 0194-911X, 09/2018, Volume 72, Issue 3, pp. 731 - 738
Journal Article
Journal Article
Hypertension, ISSN 0194-911X, 04/2018, Volume 71, Issue 4, pp. 609 - 621
Stiffening of the vasculature with aging is a strong predictor of adverse cardiovascular events, independent of all other risk factors including blood... 
Receptors | Gene expression profiling | Mineralocorticoid | Smooth muscle | Blood pressure | Myocytes | Vascular stiffening | blood pressure | receptors | HEART-FAILURE | smooth muscle | ANGIOTENSIN-II | AORTIC STIFFNESS | myocytes | mineralocorticoid | vascular stiffening | ARTERIAL STIFFNESS | DISEASE | VASCULAR INFLAMMATION | PERIPHERAL VASCULAR DISEASE | ALDOSTERONE | CARDIAC FIBROSIS | gene expression profiling | MOLECULAR-MECHANISMS | GENE-TRANSCRIPTION | Receptors, Mineralocorticoid - genetics | Gene Expression - drug effects | Muscle, Smooth, Vascular - metabolism | Receptors, Mineralocorticoid - metabolism | Humans | Cellular Senescence - drug effects | Male | Gene Expression Profiling | Spironolactone - metabolism | Fibrosis - metabolism | Mineralocorticoid Receptor Antagonists - metabolism | Spironolactone - pharmacology | Mineralocorticoid Receptor Antagonists - pharmacology | Fibrosis - prevention & control | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Muscle, Smooth, Vascular - drug effects | Cellular Senescence - physiology | Treatment Outcome | Disease Progression | Muscle, Smooth, Vascular - pathology | Animals | Exercise Tolerance - physiology | Vascular Stiffness - drug effects | Vascular Stiffness - physiology | Aged | Mice | Fibrosis - pathology | Hormone receptors | Care and treatment | Fibrosis | Aging | Physiological aspects | Mineralocorticoids | Development and progression | Health aspects | Heart diseases | Index Medicus | mineralocorticoid receptors | smooth muscle cell | aging | vascular fibrosis
Journal Article
American Journal of Hypertension, ISSN 0895-7061, 6/2012, Volume 25, Issue 6, pp. 644 - 650
Background Premature arterial stiffening and atherosclerosis are increased in patients with inflammatory arthropathies such as rheumatoid arthritis (RA),... 
arterial stiffness | blood pressure | carotid intima media thickness | hypertension | rheumatoid arthritis | Anti-TNF-α | INTIMA-MEDIA THICKNESS | RHEUMATOID-ARTHRITIS | SURROGATE | PULSE-WAVE VELOCITY | EVENTS | METAANALYSIS | MARKERS | anti-TNF-alpha | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | EXPRESSION | Prospective Studies | Arthritis, Psoriatic - physiopathology | Humans | Middle Aged | Carotid Artery Diseases - physiopathology | Leukocyte L1 Antigen Complex - drug effects | Male | Arthritis, Rheumatoid - drug therapy | Arthritis, Psoriatic - drug therapy | Adult | Female | Blood Pressure - drug effects | Blood Pressure - physiology | Antirheumatic Agents - pharmacology | Arthritis, Rheumatoid - physiopathology | Antirheumatic Agents - therapeutic use | Carotid Artery Diseases - drug therapy | Carotid Intima-Media Thickness | Spondylitis, Ankylosing - drug therapy | Treatment Outcome | Spondylitis, Ankylosing - physiopathology | Leukocyte L1 Antigen Complex - blood | Disease Progression | Leukocyte L1 Antigen Complex - physiology | Vascular Stiffness - drug effects | Vascular Stiffness - physiology | Aged | Longitudinal Studies | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Complications and side effects | Tumor necrosis factor inhibitors | Patient outcomes | Atherosclerosis | Aorta | Dosage and administration | Joint diseases | Health aspects | Risk factors | Index Medicus | Ajh-03 | anti-TNF-α | Original Contributions
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 09/2017, Volume 70, Issue 13, pp. 1683 - 1684
Journal Article
Journal Article
British Journal of Nutrition, ISSN 0007-1145, 02/2014, Volume 111, Issue 4, pp. 653 - 661
Journal Article