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1981, ISBN 8716089936, Volume no. 112, 45
Book
Circulation Research, ISSN 0009-7330, 10/2004, Volume 95, Issue 8, pp. 830 - 840
The pulmonary arteries (PA) in pulmonary arterial hypertension (PAH) are constricted and remodeled;. They have suppressed apoptosis, partly attributable to... 
Vascular remodeling | Smooth muscle | Proliferation | Apoptosis | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | proliferation | POTASSIUM CHANNELS | CARDIAC MYOCYTES | smooth muscle | RATS | apoptosis | RELAXATION | vascular remodeling | PERIPHERAL VASCULAR DISEASE | DIVERSITY | HEMATOLOGY | EXPRESSION | K+ CHANNELS | VASOCONSTRICTION | Apoptosis - drug effects | Myocytes, Smooth Muscle - pathology | Hypertrophy, Right Ventricular - etiology | Dichloroacetic Acid - therapeutic use | Hypertension, Pulmonary - chemically induced | Heart Failure - prevention & control | Oxidative Phosphorylation - drug effects | Potassium Channels, Voltage-Gated - metabolism | Vascular Resistance - drug effects | Hypertrophy, Right Ventricular - pathology | Hypertension, Pulmonary - drug therapy | Drug Evaluation, Preclinical | Myocytes, Smooth Muscle - drug effects | Heart Failure - etiology | Muscle, Smooth, Vascular - drug effects | Potassium Channels, Voltage-Gated - genetics | Cells, Cultured - drug effects | Rats | Monocrotaline - toxicity | Mitochondria - drug effects | Pulmonary Artery - drug effects | Organ Specificity | Shab Potassium Channels | Kv1.5 Potassium Channel | Cell Division - drug effects | Pulmonary Artery - cytology | Gene Expression Regulation - drug effects | Muscle, Smooth, Vascular - pathology | Animals | Dichloroacetic Acid - pharmacology | Hemodynamics - drug effects | Hypertension, Pulmonary - pathology | Hypertension, Pulmonary - complications | Index Medicus
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2008, Volume 51, Issue 22, pp. 2123 - 2129
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, pp. e104020 - e104020
Hypertension is considered as a low-grade inflammatory disease, with adaptive immunity being an important mediator of this pathology. TLR4 may have a role in... 
NADPH OXIDASE | OXIDATIVE STRESS | IMMUNE-SYSTEM | ENDOTHELIAL DYSFUNCTION | SIGNALING PATHWAY | RESISTANCE ARTERIES | MULTIDISCIPLINARY SCIENCES | IN-VIVO | SMOOTH-MUSCLE-CELLS | NF-KAPPA-B | BLOOD-PRESSURE | Reactive Oxygen Species - metabolism | Rats, Wistar | NADPH Oxidases - metabolism | Endothelium, Vascular - drug effects | Male | Heart Rate - drug effects | Phenylephrine - pharmacology | Superoxides - metabolism | Blood Pressure - drug effects | Aorta - physiopathology | Hypertension - genetics | Toll-Like Receptor 4 - antagonists & inhibitors | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Rats, Inbred SHR | Angiotensin II - pharmacology | Acetylcholine - pharmacology | Aorta - drug effects | Endothelium, Vascular - physiopathology | Toll-Like Receptor 4 - genetics | Antioxidants - pharmacology | Toll-Like Receptor 4 - metabolism | Vasoconstriction - drug effects | Hypertension - pathology | Hypertension - physiopathology | Aorta - pathology | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Cell Movement - drug effects | Muscle, Smooth, Vascular - pathology | Animals | Endothelium, Vascular - pathology | Cell Proliferation - drug effects | Oxidative Stress - drug effects | Vasodilation - drug effects | In Vitro Techniques | Potentiation | Oxidative stress | Reactive oxygen species | Biomedical research | Immunoglobulin G | Medical services | Smooth muscle | Innate immunity | mRNA | Activation | Biochemistry | Immunity | Experiments | Contraction | NAD(P)H oxidase | Ethics | Renin | Catalase | Rodents | Atherosclerosis | Phenylephrine | Toll-like receptors | Aorta | Physiology | Blood pressure | Angiotensin II | Heart diseases | Hypertension | Heparan sulfate | Muscles | Rats | Superoxide | Inflammation | Adaptive immunity | TLR4 protein | Endothelium | Heart rate | NAD | Pathology | Angiotensin | Acetylcholine | Cardiovascular diseases | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 1, pp. 55 - 60
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2006, Volume 26, Issue 11, pp. 2862 - 2870
Neuronal activity evokes localized changes in blood flow. Although this response, termed neurovascular coupling, is widely used to monitor human brain function... 
Arachidonic acid metabolites | Retina | Calcium | Glia | ATP | Blood flow | arachidonic acid metabolites | NEURONAL-ACTIVITY | 20-HETE | calcium | RAT | ASTROCYTE-MEDIATED CONTROL | CALCIUM WAVES | ARACHIDONIC-ACID | glia | NEUROSCIENCES | HEMODYNAMIC-RESPONSE | retina | NITRIC-OXIDE | blood flow | MULLER CELLS | BRAIN | Arterioles - physiology | Cytochrome P-450 Enzyme Inhibitors | Rats, Long-Evans | Arterioles - enzymology | Nitric Oxide Synthase - physiology | Male | Vasodilation - radiation effects | Retinal Vessels - enzymology | Retinal Vessels - physiology | Hydroxyeicosatetraenoic Acids - biosynthesis | Vasoconstriction - radiation effects | Photolysis | Cyclic N-Oxides - pharmacology | Inositol 1,4,5-Trisphosphate - analogs & derivatives | Eye Proteins - antagonists & inhibitors | Purinergic Antagonists | Signal Transduction - radiation effects | Cytochrome P-450 Enzyme System - physiology | Hydrazines - pharmacology | Rats | Imidazoles - pharmacology | Retinal Vessels - drug effects | Arterioles - drug effects | Vasoconstriction - drug effects | Cytochrome P-450 CYP4A - physiology | Signal Transduction - drug effects | Miconazole - pharmacology | Eye Proteins - physiology | Retinal Vessels - radiation effects | Vasodilation - drug effects | Arterioles - radiation effects | Nitric Oxide - pharmacology | Caproates - pharmacology | Vasomotor System - drug effects | Nitric Oxide Synthase - antagonists & inhibitors | Inositol 1,4,5-Trisphosphate - pharmacology | Adenosine Triphosphate - pharmacology | Vasoconstriction - physiology | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | Proadifen - pharmacology | Nitric Oxide Donors - pharmacology | Vasodilation - physiology | 8,11,14-Eicosatrienoic Acid - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Calcium Signaling - radiation effects | Cytochrome P-450 CYP4A - antagonists & inhibitors | Neuroglia - physiology | Nitric Oxide - physiology | Vasomotor System - radiation effects | Animals | Vasomotor System - physiology | Amidines - pharmacology | In Vitro Techniques | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, pp. e63784 - e63784
Vascular complications are the leading cause of morbidity and mortality in patients with diabetes. Quercetin is an important flavonoid with antioxidant and... 
C-REACTIVE PROTEIN | TUMOR-NECROSIS-FACTOR | SPONTANEOUSLY HYPERTENSIVE-RATS | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | CARDIOVASCULAR-DISEASE | FACTOR-KAPPA-B | TNF-ALPHA | PROINFLAMMATORY CYTOKINES | FACTOR-ALPHA | Tumor Necrosis Factor-alpha - metabolism | Male | NF-kappa B - metabolism | Insulin - blood | Diabetes Mellitus, Experimental - blood | Inflammation - metabolism | C-Reactive Protein - metabolism | Inflammation - drug therapy | Blood Pressure - drug effects | Diabetes Mellitus, Experimental - complications | Aorta, Thoracic - drug effects | Anti-Inflammatory Agents - pharmacology | Insulin Resistance | Rats | Antioxidants - pharmacology | Diabetic Angiopathies - blood | Diabetic Angiopathies - drug therapy | Vasoconstriction - drug effects | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Collagen - metabolism | Endothelium - drug effects | Insulin - metabolism | Animals | Endothelium - metabolism | Quercetin - pharmacology | Signal Transduction - drug effects | Leukocytes - drug effects | Blood Glucose - metabolism | Leukocytes - metabolism | Complications and side effects | Flavonoids | C-reactive protein | Flavones | Blood sugar | Bioflavonoids | Vasoconstriction | Insulin resistance | Inflammation | Insulin | Fructose | Animal models | Pathogenesis | Streptozocin | Cardiovascular disease | Glucose | Kinases | Blood | Metastases | Antioxidants | Toxicology | Chlorides | Rodents | Atherosclerosis | Phenylephrine | Aorta | Tumor necrosis factor-TNF | Blood pressure | Inhibition | Hypertension | NF-κB protein | Antiinflammatory agents | Cytokines | Complications | Diabetes mellitus | Thorax | Pharmacology | Potassium chloride | Morbidity | Studies | White blood cells | Signaling | Tumor necrosis factor | Pharmacy | Collagen | Quercetin | Infiltration | Diabetes | Immunofluorescence | Tumors | Apoptosis | Index Medicus
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 08/2008, Volume 326, Issue 2, pp. 443 - 452
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, ISSN 0193-1849, 04/2016, Volume 310, Issue 7, pp. E495 - E504
Neuregulin-1 (NRG-1) is an endothelium-derived growth factor with cardioprotective and antiatherosclerotic properties and is currently being tested in clinical... 
atherosclerosis | KIDNEY-DISEASE | heart failure | RECOMBINANT HUMAN NEUREGULIN-1 | CHRONIC HEART-FAILURE | type 1 diabetes | PHYSIOLOGY | RAT | CARDIOMYOPATHY | RECEPTOR | neuregulin-1 | MELLITUS | CARDIAC DEVELOPMENT | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | nephropathy | MICE | Cardiovascular Diseases | Diabetes Mellitus, Experimental - drug therapy | Diabetic Nephropathies - etiology | Myocardial Contraction - drug effects | Risk | Diabetes Mellitus, Type 1 - complications | Recombinant Proteins | Mesangial Cells - drug effects | Diabetic Nephropathies - physiopathology | Collagen - drug effects | Collagen - biosynthesis | Diabetes Mellitus, Experimental - complications | Plaque, Atherosclerotic - pathology | Receptor, ErbB-2 - drug effects | Disease Models, Animal | Insulin - pharmacology | Diabetic Nephropathies - pathology | Receptor, ErbB-4 - drug effects | Kidney - drug effects | Kidney Glomerulus - drug effects | Neuregulin-1 - pharmacology | Arterioles - drug effects | Vasoconstriction - drug effects | Diabetes Mellitus, Type 1 - drug therapy | Hypoglycemic Agents - pharmacology | Mice, Knockout | Animals | Apolipoproteins E - genetics | Heart - drug effects | Hypercholesterolemia - complications | Mice | Hypercholesterolemia - genetics | Heart Ventricles - drug effects | Physiological aspects | Cardiovascular diseases | Risk factors | Diabetic nephropathies | Atherosclerosis | Heart failure | Hypercholesterolemia | Type 1 diabetes | Kidney diseases | Cardiology | Apolipoproteins | Cardiomyopathy | Rodents | Collagen | Medical treatment | Index Medicus
Journal Article
American Journal of Hypertension, ISSN 0895-7061, 2017, Volume 30, Issue 4, pp. 389 - 399
BACKGROUND We investigated the influence of salt overconsumption on the functionality of the RhoA/Rho-associated kinase (ROCK) pathway and calcium regulation... 
Calcium signaling | Hypertension | Calcium sensitization | High-salt | Vascular smooth muscle cell | Blood pressure | Vascular dysfunction | blood pressure | RHO-ASSOCIATED KINASE | TRANSLOCATION | SENSITIVE RATS | ACTIVATION | PROTEIN-KINASE | calcium signaling | VASCULAR SMOOTH-MUSCLE | BLOOD-PRESSURE | high-salt | calcium sensitization | vascular dysfunction | CONTRACTION | PERIPHERAL VASCULAR DISEASE | vascular smooth muscle cell | hypertension | MYOSIN PHOSPHATASE | Rats, Wistar | Sodium Chloride, Dietary - pharmacology | Calcium - metabolism | Male | Mesenteric Arteries - drug effects | Ryanodine Receptor Calcium Release Channel - metabolism | Aorta - metabolism | Stromal Interaction Molecule 1 - drug effects | Sarcoplasmic Reticulum Calcium-Transporting ATPases - drug effects | Inositol 1,4,5-Trisphosphate Receptors - drug effects | Phenylephrine - pharmacology | rho-Associated Kinases - metabolism | Inositol 1,4,5-Trisphosphate Receptors - metabolism | rho-Associated Kinases - drug effects | Phosphorylation - drug effects | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | ORAI1 Protein - drug effects | Amides - pharmacology | Mesenteric Arteries - cytology | ORAI1 Protein - metabolism | Vasoconstrictor Agents - pharmacology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Aorta - drug effects | Enzyme Inhibitors - pharmacology | Rats | Ryanodine Receptor Calcium Release Channel - drug effects | Mesenteric Arteries - metabolism | Vasoconstriction - drug effects | rho GTP-Binding Proteins - drug effects | Stromal Interaction Molecule 1 - metabolism | Protein Phosphatase 1 - metabolism | Animals | Protein Phosphatase 1 - drug effects | Signal Transduction - drug effects | rho GTP-Binding Proteins - metabolism | Pyridines - pharmacology | Aorta - cytology | Physiological aspects | Salt | Research | Health aspects | Rattus | Index Medicus | Blood Vessels | Original
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2010, Volume 176, Issue 3, pp. 1306 - 1315
Brain hemodynamics in cerebral malaria (CM) is poorly understood, with apparently conflicting data showing microcirculatory hypoperfusion and normal or even... 
Pathology | SEQUESTRATION | PATHOGENESIS | AFRICAN CHILDREN | PLASMODIUM-FALCIPARUM | IN-VIVO | VOLUME | SUBARACHNOID HEMORRHAGE | RED-BLOOD-CELLS | MICE | BERGHEI | PATHOLOGY | Body Temperature - drug effects | Plasmodium berghei - physiology | Parasitemia - drug therapy | Nimodipine - pharmacology | Vasospasm, Intracranial - complications | Malaria, Cerebral - physiopathology | Microcirculation - drug effects | Microcirculation - physiology | Artemisinins - pharmacology | Arterioles - physiopathology | Erythrocytes - pathology | Parasitemia - physiopathology | Vasospasm, Intracranial - parasitology | Malaria, Cerebral - parasitology | Cerebrovascular Circulation - drug effects | Mice, Inbred C57BL | Parasitemia - complications | Cell Adhesion - drug effects | Arterioles - drug effects | Vasoconstriction - drug effects | Erythrocytes - drug effects | Nimodipine - therapeutic use | Arterioles - pathology | Animals | Artemisinins - therapeutic use | Leukocytes - parasitology | Malaria, Cerebral - complications | Vasospasm, Intracranial - physiopathology | Malaria, Cerebral - drug therapy | Survival Analysis | Parasitemia - parasitology | Leukocytes - drug effects | Mice | Vasodilation - drug effects | Erythrocytes - parasitology | Plasmodium berghei - drug effects | Vasospasm, Intracranial - drug therapy | Index Medicus | Abridged Index Medicus | Regular
Journal Article