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Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 05/2016, Volume 14, Issue 5, pp. 1011 - 1020
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2015, Volume 35, Issue 4, pp. 838 - 844
Objective-We tested the hypothesis that endothelial peroxisome proliferator-activated receptor-. protects against vascular thrombosis using a transgenic mouse... 
endothelium | P-selectin | thrombosis | CELLS | ATHEROSCLEROSIS | MECHANISMS | PIOGLITAZONE | VENOUS THROMBOGENESIS | INSULIN-RESISTANCE | ACTIVATED-RECEPTOR-GAMMA | PERIPHERAL VASCULAR DISEASE | INTERFERENCE | DYSFUNCTION | HEMATOLOGY | ADIPOSE-TISSUE | Carotid Artery Diseases - prevention & control | P-Selectin - metabolism | Humans | Leukocyte Rolling | Male | PPAR gamma - metabolism | RNA, Messenger - metabolism | Venous Thrombosis - immunology | Time Factors | Carotid Artery Diseases - pathology | Vena Cava, Inferior - pathology | Venous Thrombosis - prevention & control | Thrombosis - prevention & control | Carotid Artery Diseases - metabolism | Neutrophils - metabolism | Disease Models, Animal | P-Selectin - immunology | PPAR gamma - genetics | Carotid Artery Diseases - immunology | P-Selectin - antagonists & inhibitors | Carotid Artery, Common - metabolism | Endothelial Cells - metabolism | Down-Regulation | Mice, Inbred C57BL | Venous Thrombosis - metabolism | Neutrophils - immunology | Thrombosis - immunology | Mice, Transgenic | Vena Cava, Inferior - metabolism | P-Selectin - genetics | Antibodies - pharmacology | Endothelial Cells - immunology | Thrombosis - pathology | Thrombosis - metabolism | Animals | Carotid Artery Diseases - genetics | Carotid Artery, Common - pathology | Thrombosis - genetics | Venous Thrombosis - genetics | Mutation | Venous Thrombosis - pathology | Endothelial Cells - pathology | Endothelial Cells - drug effects | Index Medicus | NF-κB | P-Selectin | Thrombosis | PPARγ | Endothelium
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 04/2019, Volume 10, Issue 1, pp. 1916 - 1916
Potentiation of neutrophil extracellular trap (NET) release is one mechanism by which antiphospholipid antibodies (aPL Abs) effect thrombotic events in... 
ANTIBODIES | NEUTROPHIL EXTRACELLULAR TRAPS | PEPTIDYLARGININE DEIMINASE INHIBITION | LOW-DOSE ASPIRIN | BETA-GLYCOPROTEIN I | MULTIDISCIPLINARY SCIENCES | BETA-2-GLYCOPROTEIN-I | VENOUS THROMBOSIS | UPDATE | RELEASE | TISSUE FACTOR | Antibodies, Antiphospholipid - blood | Immunoglobulin G - blood | Extracellular Traps - metabolism | Humans | Male | Extracellular Traps - immunology | Venous Thrombosis - immunology | Adenosine A2 Receptor Agonists - pharmacology | Dipyridamole - pharmacology | Extracellular Traps - drug effects | Receptor, Adenosine A2A - immunology | Antiphospholipid Syndrome - genetics | Receptor, Adenosine A2A - genetics | Cyclic AMP - metabolism | Disease Models, Animal | Phenethylamines - pharmacology | Signal Transduction | Venous Thrombosis - drug therapy | Adenosine - immunology | Antiphospholipid Syndrome - drug therapy | Mice, Inbred C57BL | Neutrophils - drug effects | Gene Expression Regulation | Neutrophils - immunology | Vena Cava, Inferior - metabolism | Adenosine - pharmacology | Vena Cava, Inferior - immunology | Antiphospholipid Syndrome - immunology | Fibrinolytic Agents - pharmacology | Vena Cava, Inferior - drug effects | Animals | Antiphospholipid Syndrome - pathology | Adenosine - analogs & derivatives | Cyclic AMP - immunology | Adenosine - metabolism | Mice | Venous Thrombosis - genetics | Venous Thrombosis - pathology | Index Medicus
Journal Article
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 11/2012, Volume 32, Issue 11, pp. 2616 - 2624
OBJECTIVE—Assessment of thrombus inflammation in vivo could provide new insights into deep vein thrombosis (DVT) resolution. Here, we develop and evaluate 2... 
Molecular imaging | Deep vein thrombosis | Inflammation | Post-thrombotic syndrome | Macrophage | RECRUITMENT | RAT | ATHEROSCLEROSIS | macrophage | DEEP-VEIN THROMBOSIS | molecular imaging | MICROSCOPY | POSTTHROMBOTIC SYNDROME | PLASMINOGEN | deep vein thrombosis | LEUKOCYTES | inflammation | post-thrombotic syndrome | MOUSE MODEL | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Inflammation - chemically induced | Inflammation - pathology | Prognosis | Venous Thrombosis - chemically induced | Venous Thrombosis - diagnostic imaging | Male | Tomography, X-Ray Computed | Saphenous Vein - immunology | Jugular Veins - metabolism | Saphenous Vein - metabolism | Jugular Veins - immunology | Inflammation - metabolism | Dextrans | Venous Thrombosis - immunology | Time Factors | Femoral Vein - pathology | Chlorides | Inflammation - diagnostic imaging | Macrophages - immunology | Disease Models, Animal | Biomarkers - metabolism | Severity of Illness Index | Femoral Vein - metabolism | Reproducibility of Results | Jugular Veins - pathology | Macrophages - pathology | Mice, Inbred C57BL | Venous Thrombosis - metabolism | Fluorescein-5-isothiocyanate - analogs & derivatives | Molecular Imaging - methods | Saphenous Vein - pathology | Inflammation - immunology | Femoral Vein - immunology | Phlebography | Ferric Compounds | Microscopy, Confocal | Animals | Mice | Matrix Metalloproteinases - metabolism | Venous Thrombosis - pathology | Fluorescent Dyes | Microscopy, Fluorescence | Index Medicus | intravital microscopy
Journal Article
Clinical Rheumatology, ISSN 0770-3198, 03/2019, Volume 38, Issue 3, pp. 885 - 893
ObjectiveTo validate the association of thrombotic events with positive lupus anticoagulant (LA) and co-presence of anti-RNP/Sm, as well as the diagnostic... 
Anti-RNP/Sm | Systemic lupus erythematosus | Thrombosis | Diagnostic accuracy | Lupus anticoagulant | Anti-RNP | DIAGNOSIS | RISK-FACTORS | ANTIENDOTHELIAL CELL ANTIBODIES | VENOUS THROMBOSIS | ANTICOAGULANT | ASYMPTOMATIC CARRIERS | RHEUMATOLOGY | ANTIPHOSPHOLIPID SYNDROME | DISEASE-ACTIVITY | NEUTROPHIL EXTRACELLULAR TRAPS | REVISED CRITERIA | Antibodies, Anticardiolipin - immunology | Multivariate Analysis | Glucocorticoids - administration & dosage | Antibodies, Antinuclear - immunology | Humans | Middle Aged | Antibodies, Antiphospholipid - immunology | Male | snRNP Core Proteins - immunology | Case-Control Studies | Young Adult | Lupus Coagulation Inhibitor - immunology | Immunoglobulin G - immunology | Lupus Erythematosus, Systemic - drug therapy | Lupus Erythematosus, Systemic - immunology | Adult | Female | Prednisone - administration & dosage | Lupus Erythematosus, Systemic - epidemiology | Risk Factors | Thrombosis - immunology | Logistic Models | Thrombosis - epidemiology | Autoantibodies - immunology | Adolescent | beta 2-Glycoprotein I - immunology | Lupus | Medical research | Care and treatment | Corticosteroids | Comorbidity | Antibodies | Anticoagulants (Medicine) | Risk factors | Blood clot | Viral antibodies | Analysis | Medicine, Experimental | Immunoglobulin M | Immunoglobulins | Immunoglobulin G | Prednisone | Diagnosis | Health risk assessment | Patients
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2011, Volume 70, Issue 6, pp. 1083 - 1086
Journal Article
Lupus, ISSN 0961-2033, 11/2012, Volume 21, Issue 13, pp. 1423 - 1432
Objective: Patients with systemic lupus erythematosus (SLE) have an increased risk of developing vascular diseases (VD) such as myocardial infarction, stroke... 
cardiovascular disease | platelet | Systemic lupus erythematosus | complement | venous thrombosis | COMPLEMENT ACTIVATION | COMPLEXES | ANTIPHOSPHOLIPID ANTIBODIES | RECEPTOR | RHEUMATOLOGY | DAMAGE | DISEASE | INDEX | BINDING | ASSOCIATION | Lupus Coagulation Inhibitor - blood | Up-Regulation | Lupus Erythematosus, Systemic - complications | Blood Platelets - immunology | Humans | Middle Aged | Venous Thrombosis - blood | Male | Lupus Erythematosus, Systemic - blood | Case-Control Studies | Complement C4b - analysis | Complement C1q - analysis | Young Adult | Flow Cytometry | Venous Thrombosis - immunology | Lupus Erythematosus, Systemic - immunology | Aged, 80 and over | Adult | Female | Complement Pathway, Classical | Complement C3d - analysis | Risk Factors | Biomarkers - blood | Venous Thrombosis - etiology | Peptide Fragments - analysis | Platelet Activation | Aged | Index Medicus | Myocardial infarction | complement component C4 | Anticoagulants | Flow cytometry | Stroke | Centrifugation | Data processing | Thrombosis | Blood | Risk factors | antiphospholipid antibodies | Complement component C1q | Complement activation | Vascular diseases | Complement component C3 | Platelets | Sexually-transmitted diseases | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Reumatologi och inflammation
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, pp. e99386 - e99386
Anti-phospholipid (aPL) antibodies are important contributors to development of thrombosis in patients with the autoimmune rheumatic disease systemic lupus... 
Complement C4b - immunology | Blood Platelets - immunology | Humans | Middle Aged | Platelet Activation - immunology | Risk Factors | Antibodies, Antiphospholipid - immunology | Thrombosis - immunology | Cardiolipins - immunology | Male | Lupus Erythematosus, Systemic - blood | Complement Activation - immunology | Young Adult | Peptide Fragments - immunology | Adolescent | Lupus Erythematosus, Systemic - immunology | Aged, 80 and over | Adult | Female | Aged | Thrombosis - blood | Stroke (Disease) | Lupus | Rheumatoid factor | Systemic lupus erythematosus | Phospholipids | Antiphospholipid antibodies | Thrombosis | Blood clot | Shipping industry | Heart attacks | Laboratories | Antibodies | Cardiovascular disease | Activation | Complement | Arthritis | Kinases | Risk factors | Inflammatory diseases | Immunology | Blood platelets | Thromboembolism | Deposition | Stroke | Immunoglobulins | Mortality | Rheumatology | Health risks | Rheumatic diseases | Risk analysis | Patients | Studies | Complement component C1q | Chronic conditions | Complement activation | Hospitals | Rheumatoid arthritis | Systemic sclerosis | Autoimmune diseases | Cardiovascular diseases | Platelets | Classical pathway | Index Medicus | Rheumatology and Autoimmunity | Clinical Medicine | Basic Medicine | Medical and Health Sciences | Microbiology in the medical area | Medicin och hälsovetenskap | Reumatologi och inflammation | Medicinska och farmaceutiska grundvetenskaper | Immunologi inom det medicinska området | Klinisk medicin | Mikrobiologi inom det medicinska området | Immunology in the medical area
Journal Article