Neuroscience and Biobehavioral Reviews, ISSN 0149-7634, 01/2020, Volume 108, pp. 48 - 77
The ventral tegmental area dopamine (VTA-DA) mesolimbic circuit processes emotional, motivational, and social reward associations together with their more...
Dopamine | Glucocorticoids | BDNF | Mesocorticolimbic system | Depression | Cognition | Stress | Habituation | Microglia | Addiction | Neurodegeneration | Opioids | CRH | Coping | Ventral tegmental area | Adaptation
Dopamine | Glucocorticoids | BDNF | Mesocorticolimbic system | Depression | Cognition | Stress | Habituation | Microglia | Addiction | Neurodegeneration | Opioids | CRH | Coping | Ventral tegmental area | Adaptation
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 12/2019, Volume 376, p. 112190
Adolescent alcohol drinking has been linked to increased risk for drug abuse during adulthood. Nicotine microinjected directly into the posterior ventral...
Adolescent alcohol | Dopamine | Ventral tegmental area | Mesolimbic | α7 nicotinic acetylcholine receptor | Nicotine
Adolescent alcohol | Dopamine | Ventral tegmental area | Mesolimbic | α7 nicotinic acetylcholine receptor | Nicotine
Journal Article
Progress in Neuropsychopharmacology & Biological Psychiatry, ISSN 0278-5846, 12/2019, Volume 95, p. 109681
Behavioral sensitization to repeated psychostimulant administration has been proposed to reflect many of the neurochemical and behavioral changes that are...
Amphetamine | Methamphetamine | GABA | Sensitization | Prefrontal cortex | Inhibition | Psychostimulants | ANTERIOR CINGULATE CORTEX | MESSENGER-RNA EXPRESSION | PSYCHIATRY | INTERNEURON DIVERSITY SERIES | NEUROSCIENCES | CLINICAL NEUROLOGY | VENTRAL TEGMENTAL AREA | NUCLEUS-ACCUMBENS | DOPAMINE NEURONS | BASKET CELLS | PHARMACOLOGY & PHARMACY | GAMMA-AMINOBUTYRIC-ACID | GABA(A) RECEPTORS | ORBITOFRONTAL CORTEX
Amphetamine | Methamphetamine | GABA | Sensitization | Prefrontal cortex | Inhibition | Psychostimulants | ANTERIOR CINGULATE CORTEX | MESSENGER-RNA EXPRESSION | PSYCHIATRY | INTERNEURON DIVERSITY SERIES | NEUROSCIENCES | CLINICAL NEUROLOGY | VENTRAL TEGMENTAL AREA | NUCLEUS-ACCUMBENS | DOPAMINE NEURONS | BASKET CELLS | PHARMACOLOGY & PHARMACY | GAMMA-AMINOBUTYRIC-ACID | GABA(A) RECEPTORS | ORBITOFRONTAL CORTEX
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 11250 - 8
Although it is well known that food intake is affected by the palatability of food, the actual effect of flavoring on regulation of energy-homeostasis and...
NERVOUS-SYSTEM CONTROL | GLUCOSE-INGESTION | FOOD-INTAKE | MULTIDISCIPLINARY SCIENCES | SWEET-TASTE | AROMA | APPETITE | REWARD | BRAIN | Ventral tegmentum | Energy balance | Palatability | Food intake | Brain mapping | Homeostasis | Functional magnetic resonance imaging | Reinforcement | Hypothalamus | Glucose | Flavor
NERVOUS-SYSTEM CONTROL | GLUCOSE-INGESTION | FOOD-INTAKE | MULTIDISCIPLINARY SCIENCES | SWEET-TASTE | AROMA | APPETITE | REWARD | BRAIN | Ventral tegmentum | Energy balance | Palatability | Food intake | Brain mapping | Homeostasis | Functional magnetic resonance imaging | Reinforcement | Hypothalamus | Glucose | Flavor
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 03/2019, Volume 10, Issue 1, pp. 1455 - 13
The ventral tegmental area (VTA) is a heterogeneous midbrain structure, containing neurons and astrocytes, that coordinates behaviors by integrating activity...
GLUTAMATE TRANSPORTER GLT-1 | DOPAMINE NEURONS | ACTIVATION | INFORMATION | MULTIDISCIPLINARY SCIENCES | DYNAMICS | GABA NEURONS | CURRENTS | CONDITIONAL DELETION | GLIAL-CELLS | RECEPTORS | Ventral tegmentum | Dopamine | Mesencephalon | Neurons | Astrocytes | Circuits | γ-Aminobutyric acid | Motivation | Avoidance behavior | Reinforcement | Behavior | Excitation | Glutamatergic transmission | Glutamic acid transporter | Approach behavior | Transporter | Avoidance
GLUTAMATE TRANSPORTER GLT-1 | DOPAMINE NEURONS | ACTIVATION | INFORMATION | MULTIDISCIPLINARY SCIENCES | DYNAMICS | GABA NEURONS | CURRENTS | CONDITIONAL DELETION | GLIAL-CELLS | RECEPTORS | Ventral tegmentum | Dopamine | Mesencephalon | Neurons | Astrocytes | Circuits | γ-Aminobutyric acid | Motivation | Avoidance behavior | Reinforcement | Behavior | Excitation | Glutamatergic transmission | Glutamic acid transporter | Approach behavior | Transporter | Avoidance
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 13
A new mechanism is revealed by which a polyphenol, rosmarinic acid (RA), suppresses amyloid β (Aβ) accumulation in mice. Here we examined the brains of mice...
Ventral tegmentum | Dopamine | Secretion | Substantia nigra | Cortex | Gene expression | Monoamines | Amine oxidase (flavin-containing) | Signal transduction | DNA microarrays | Dihydroxyphenylacetic acid | Rosmarinic acid | Norepinephrine | Levodopa | Alzheimer's disease
Ventral tegmentum | Dopamine | Secretion | Substantia nigra | Cortex | Gene expression | Monoamines | Amine oxidase (flavin-containing) | Signal transduction | DNA microarrays | Dihydroxyphenylacetic acid | Rosmarinic acid | Norepinephrine | Levodopa | Alzheimer's disease
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1873 - 16
The lateral hypothalamic area (LHA) is essential for ingestive behavior but it remains unclear how LHA neurons coordinate feeding vs. drinking. Most LHA...
CORTICOTROPIN-RELEASING HORMONE | LOCALIZATION | NUCLEUS | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | OREXIN | MODULATE | MESOLIMBIC DOPAMINE SYSTEM | PROJECTIONS | REWARD | VENTRAL TEGMENTAL AREA | Ventral tegmentum | Drinking water | Subpopulations | Feeding behavior | Neurons | Drinking behavior | Substantia nigra | Hypothalamus (lateral) | Hypothalamus | Neurotensin | Dehydration | Feeding | γ-Aminobutyric acid | Neural networks | Water intake | Food consumption | Polydipsia
CORTICOTROPIN-RELEASING HORMONE | LOCALIZATION | NUCLEUS | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | OREXIN | MODULATE | MESOLIMBIC DOPAMINE SYSTEM | PROJECTIONS | REWARD | VENTRAL TEGMENTAL AREA | Ventral tegmentum | Drinking water | Subpopulations | Feeding behavior | Neurons | Drinking behavior | Substantia nigra | Hypothalamus (lateral) | Hypothalamus | Neurotensin | Dehydration | Feeding | γ-Aminobutyric acid | Neural networks | Water intake | Food consumption | Polydipsia
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 5262 - 9
Parkinson's disease (PD) is the second most common neurodegenerative disorder and is characterized by motor deficits such as tremor, rigidity and bradykinesia....
ATIPAMEZOLE | NOREPINEPHRINE | MULTIDISCIPLINARY SCIENCES | DISEASE | LOCUS-COERULEUS | LEADS | DOPAMINERGIC-NEURONS | NORADRENALINE | SUBSTANTIA-NIGRA | NUCLEOLAR DISRUPTION | DEGENERATION | Neuroprotection | Basal ganglia | Animal models | Parkinson's disease | Substantia nigra | Mimicry | Genotype & phenotype | Neurodegeneration | Autopsy | Phenylephrine | Neostriatum | Locus coeruleus | Movement disorders | Dopamine receptors | Ventral tegmentum | Reboxetine | Phenotypes | Cell survival | Dopamine | Tremor | Neurodegenerative diseases | Neurons | rRNA | Central nervous system diseases | Norepinephrine | MPTP
ATIPAMEZOLE | NOREPINEPHRINE | MULTIDISCIPLINARY SCIENCES | DISEASE | LOCUS-COERULEUS | LEADS | DOPAMINERGIC-NEURONS | NORADRENALINE | SUBSTANTIA-NIGRA | NUCLEOLAR DISRUPTION | DEGENERATION | Neuroprotection | Basal ganglia | Animal models | Parkinson's disease | Substantia nigra | Mimicry | Genotype & phenotype | Neurodegeneration | Autopsy | Phenylephrine | Neostriatum | Locus coeruleus | Movement disorders | Dopamine receptors | Ventral tegmentum | Reboxetine | Phenotypes | Cell survival | Dopamine | Tremor | Neurodegenerative diseases | Neurons | rRNA | Central nervous system diseases | Norepinephrine | MPTP
Journal Article
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Full Text
Neuropharmacology of the mesolimbic system and associated circuits on social hierarchies
Neuropharmacology, ISSN 0028-3908, 11/2019, Volume 159, p. 107498
Most socially living species are organized hierarchically, primarily based on individual differences in social dominance. Dominant individuals typically gain...
Nucleus accumbens | Mitochondria | Dopamine | Mesolimbic system | Dominance | Ventral tegmental area | Social hierarchy | DOPAMINERGIC ACTIVITY | CHRONIC STRESS | REWARD | NEUROSCIENCES | NUCLEUS-ACCUMBENS | DOMINANCE RANK | LONG-TERM ESTABLISHMENT | DEFEAT STRESS | PHARMACOLOGY & PHARMACY | Ventral segmental area | NEURAL MECHANISMS | PSYCHOSOCIAL STRESS | REPRODUCTIVE SUCCESS
Nucleus accumbens | Mitochondria | Dopamine | Mesolimbic system | Dominance | Ventral tegmental area | Social hierarchy | DOPAMINERGIC ACTIVITY | CHRONIC STRESS | REWARD | NEUROSCIENCES | NUCLEUS-ACCUMBENS | DOMINANCE RANK | LONG-TERM ESTABLISHMENT | DEFEAT STRESS | PHARMACOLOGY & PHARMACY | Ventral segmental area | NEURAL MECHANISMS | PSYCHOSOCIAL STRESS | REPRODUCTIVE SUCCESS
Journal Article
Brain Research, ISSN 0006-8993, 11/2019, p. 146552
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 05/2018, Volume 24, Issue 11, pp. 1 - 17
The diurnal regulation of dopamine is important for normal physiology and diseases such as addiction. Here we find a novel role for the CLOCK protein to...
Phenols | Usage | Cocaine | Dopamine | Research | Genetic transcription | Tyrosine | Circadian rhythms | Ventral tegmentum | Drug abuse | Narcotics | Transcription | Hydroxylase | CLOCK protein | Metabolism | Cyclic AMP response element-binding protein | Tyrosine 3-monooxygenase | SIRT1 protein | Diurnal | Proteins | NAD | Reinforcement | Conditioning | Redox properties | Dopamine receptors
Phenols | Usage | Cocaine | Dopamine | Research | Genetic transcription | Tyrosine | Circadian rhythms | Ventral tegmentum | Drug abuse | Narcotics | Transcription | Hydroxylase | CLOCK protein | Metabolism | Cyclic AMP response element-binding protein | Tyrosine 3-monooxygenase | SIRT1 protein | Diurnal | Proteins | NAD | Reinforcement | Conditioning | Redox properties | Dopamine receptors
Journal Article