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Circulation, ISSN 0009-7322, 2013, Volume 128, Issue 18, pp. 2016 - 2025
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 05/2016, Volume 133, Issue 20, pp. 1936 - 1944
Journal Article
CIRCULATION-HEART FAILURE, ISSN 1941-3289, 07/2016, Volume 9, Issue 7, pp. e002636 - e002636
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 4/2017, Volume 95, Issue 4, pp. 381 - 393
Right ventricular (RV) function determines prognosis in pulmonary arterial hypertension (PAH). We hypothesize that ischemia causes RV dysfunction in PAH by... 
Human Genetics | Ischemia-reperfusion injury | Biomedicine | Diastolic dysfunction | Internal Medicine | Mdivi-1 | Pulmonary arterial hypertension | Mitochondrial division inhibitor 1 | Molecular Medicine | Mitochondrial membrane potential | MEDICINE, RESEARCH & EXPERIMENTAL | RECRUITMENT | REPERFUSION INJURY | HEART | HYPERTROPHY | CARDIAC-ARREST | INHIBITION | METABOLISM | ARTERIAL-HYPERTENSION | DEPHOSPHORYLATION | GENETICS & HEREDITY | DYNAMIN-RELATED PROTEIN-1 | Mitochondrial Dynamics | Dynamins - metabolism | Myocardial Reperfusion Injury - complications | Hypertension, Pulmonary - physiopathology | Hypertension, Pulmonary - metabolism | Mitochondria - metabolism | Mitochondria - pathology | Rats, Sprague-Dawley | Myocardial Reperfusion Injury - physiopathology | Myocardial Reperfusion Injury - metabolism | Myocardial Reperfusion Injury - pathology | Animals | Mitochondrial Proteins - metabolism | Ventricular Dysfunction, Right - etiology | Ventricular Dysfunction, Right - physiopathology | Hypertension, Pulmonary - etiology | Hypertension, Pulmonary - pathology | Ventricular Dysfunction, Right - metabolism | Ventricular Dysfunction, Right - pathology | Care and treatment | Usage | Prognosis | Patient outcomes | Analysis | Ventricular function | Research | Gene expression | Guanosine triphosphatase | Health aspects | Pulmonary hypertension | Index Medicus | ischemia-reperfusion injury | diastolic dysfunction | mitochondrial division inhibitor 1 | pulmonary arterial hypertension | mitochondrial membrane potential
Journal Article
Circulation, ISSN 0009-7322, 09/2015, Volume 132, Issue 10, pp. 932 - 943
Journal Article
Cardiovascular Research, ISSN 0008-6363, 08/2016, Volume 111, Issue 3, pp. 184 - 193
Pulmonary hypertension is a progressive disease with poor prognosis, characterized by pathological inward remodelling and loss of patency of the lung... 
Hypertension | Hypoxia | Pulmonary | Pulmonary heart disease | CELLS | LUNG | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOGENESIS | PULMONARY ARTERIAL-HYPERTENSION | RECEPTOR | BREAST-CANCER | HEART | GENE | EXPRESSION | MICRORNA | Receptor, IGF Type 1 - metabolism | Receptor, IGF Type 1 - antagonists & inhibitors | Ventricular Dysfunction, Right - genetics | Humans | Heart Failure - physiopathology | Hypertension, Pulmonary - physiopathology | Male | MicroRNAs - metabolism | Hypertension, Pulmonary - prevention & control | Hypoxia - metabolism | Heart Failure - prevention & control | Hypertrophy, Right Ventricular - physiopathology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Ventricular Dysfunction, Right - physiopathology | Lung - metabolism | Receptor, IGF Type 1 - deficiency | Hypertrophy, Right Ventricular - metabolism | Ventricular Dysfunction, Right - metabolism | Genetic Predisposition to Disease | Signal Transduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Mice, Inbred C57BL | Gene Expression Regulation | Heart Failure - genetics | Hypertension, Pulmonary - genetics | Heart Failure - metabolism | Hypertension, Pulmonary - metabolism | Hypoxia - complications | Imidazoles - pharmacology | Receptor, IGF Type 1 - genetics | Mice, Knockout | Ventricular Dysfunction, Right - prevention & control | Hypoxia - genetics | Phenotype | Animals | Heart Ventricles - physiopathology | Receptors, Somatomedin - metabolism | Heart Ventricles - metabolism | MicroRNAs - genetics | Pyridines - pharmacology | Ventricular Function, Right | Index Medicus
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 05/2010, Volume 108, Issue 5, pp. 1148 - 1153
Journal Article
Circulation, ISSN 0009-7322, 02/2018, Volume 137, Issue 9, pp. 910 - 924
Journal Article
Basic Research in Cardiology, ISSN 0300-8428, 3/2013, Volume 108, Issue 2, pp. 1 - 13
Pulmonary arterial hypertension (PAH) is a fatal disease for which no cure is yet available. The leading cause of death in PAH is right ventricular (RV)... 
Right heart disease | Medicine & Public Health | Fibrosis | MAL | Cardiac fibroblasts | Fn14 | Cardiology | TRANSCRIPTION FACTORS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | APOPTOSIS TWEAK | PULMONARY ARTERIAL-HYPERTENSION | SRF ACTIVITY | ENDOTHELIN SYSTEM | WEAK INDUCER | CARDIAC-HYPERTROPHY | CEREBRAL-ISCHEMIA | MOLECULAR-MECHANISMS | Immunohistochemistry | Tumor Necrosis Factors - genetics | Up-Regulation | Cell Proliferation | TWEAK Receptor | Receptors, Tumor Necrosis Factor - physiology | Hypertrophy, Right Ventricular - physiopathology | Trans-Activators - genetics | Apoptosis Regulatory Proteins - genetics | Ventricular Dysfunction, Right - physiopathology | Cell Differentiation | Membrane Proteins - metabolism | Endothelin-1 - physiology | Fibrosis - prevention & control | Hypertrophy, Right Ventricular - metabolism | Real-Time Polymerase Chain Reaction | Ventricular Dysfunction, Right - metabolism | Signal Transduction | Membrane Proteins - genetics | Tumor Necrosis Factors - metabolism | Rats | Familial Primary Pulmonary Hypertension | Myocardium - pathology | Transcription Factors - genetics | Rats, Sprague-Dawley | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Transcription Factors - metabolism | Ventricular Dysfunction, Right - prevention & control | Collagen - metabolism | Cytokine TWEAK | Animals | Fluorescent Antibody Technique | Hypertrophy, Right Ventricular - prevention & control | Trans-Activators - metabolism | Mice | Myofibroblasts | Hypertension, Pulmonary - complications | Heart | Endothelin | Collagen | Fibroblast growth factors | Heart diseases | Pulmonary hypertension | Index Medicus | Original Contribution
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 3/2013, Volume 91, Issue 3, pp. 333 - 346
Journal Article
Cardiovascular Drugs and Therapy, ISSN 0920-3206, 12/2016, Volume 30, Issue 6, pp. 587 - 598
Endoplasmic reticulum (ER) stress contributes to pulmonary artery hypertension (PAH). However, the exact roles of ER stress in right ventricular (RV)... 
Medicine & Public Health | Endoplasmic reticulum (ER) stress | Pulmonary artery hypertension | Inflammation | Cardiology | Right ventricular dysfunction | Apoptosis | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | RECEPTOR BLOCKADE | METAANALYSIS | MODEL | UNFOLDED PROTEIN RESPONSE | THERAPY | RIGHT HEART-FAILURE | GENE | CARDIOVASCULAR-DISEASE | PHARMACOLOGY & PHARMACY | INHIBITORS | Transcription Factor CHOP - genetics | Phenylbutyrates - therapeutic use | Apoptosis - drug effects | eIF-2 Kinase - metabolism | Monocrotaline | Hypertension, Pulmonary - physiopathology | Male | RNA, Messenger - metabolism | Activating Transcription Factor 6 - genetics | Hypertension, Pulmonary - chemically induced | Heat-Shock Proteins - genetics | Peptide Fragments - blood | Phenylbutyrates - pharmacology | Ventricular Dysfunction, Right - physiopathology | Hypertension, Pulmonary - drug therapy | Membrane Proteins - metabolism | Ventricular Dysfunction, Right - chemically induced | Ventricular Dysfunction, Right - metabolism | Natriuretic Peptide, Brain - blood | Protein-Serine-Threonine Kinases - metabolism | eIF-2 Kinase - genetics | Endoplasmic Reticulum Stress - drug effects | Membrane Proteins - genetics | Heat-Shock Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Ventricular Dysfunction, Right - drug therapy | Hypertension, Pulmonary - metabolism | Rats, Sprague-Dawley | Activating Transcription Factor 6 - metabolism | Animals | Myocytes, Cardiac - drug effects | Heart Ventricles - physiopathology | Myocytes, Cardiac - metabolism | Heart Ventricles - metabolism | Transcription Factor CHOP - metabolism | Enzymes | Inositol | Interleukins | Medicine, Preventive | Protein kinases | Pulmonary hypertension | Protein binding | Preventive health services | Index Medicus
Journal Article
Annals of the American Thoracic Society, ISSN 2325-6621, 02/2013, Volume 10, Issue 1, pp. 1 - 9
Journal Article