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Nature, ISSN 0028-0836, 01/2019, Volume 565, Issue 7740, pp. 505 - 510
The increasing prevalence of diabetes has resulted in a global epidemic1. Diabetes is a major cause of blindness, kidney failure, heart attacks, stroke and... 
PLURIPOTENT STEM-CELLS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | EXPANSION | GENERATION | ANGIOPOIETIN-2 | MELLITUS | PERICYTES | LINES | Blood Vessels - growth & development | Basement Membrane - drug effects | Pericytes - drug effects | Blood Vessels - pathology | Humans | Pericytes - cytology | Hyperglycemia - complications | Venules - drug effects | Organoids - transplantation | Arteries - cytology | Basement Membrane - pathology | Intercellular Signaling Peptides and Proteins - metabolism | Diabetic Angiopathies - pathology | Inflammation Mediators - pharmacology | Diabetic Angiopathies - enzymology | Arterioles - cytology | Receptor, Notch3 - metabolism | Organoids - pathology | Pluripotent Stem Cells - cytology | Signal Transduction | Basement Membrane - cytology | Organoids - cytology | Arteries - drug effects | Venules - cytology | Arterioles - drug effects | Blood Vessels - cytology | Amyloid Precursor Protein Secretases - metabolism | Animals | Endothelial Cells - cytology | Models, Biological | Pluripotent Stem Cells - drug effects | Blood Vessels - drug effects | Organoids - drug effects | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | In Vitro Techniques | Endothelial Cells - drug effects | Type 2 diabetes | Blood vessels | Research | Diabetes | Heart | Diabetic retinopathy | Epidemics | Regulators | Nuclear magnetic resonance--NMR | Transplants & implants | Arterioles | Stem cell transplantation | Blood | Arteries | Angiogenesis | Hyperglycemia | Vascular diseases | Organoids | Amputation | Heart diseases | Thickening | Stroke | Cytokines | Diabetes mellitus | Inflammation | Gene expression | Patients | Endothelial cells | Endothelium | Collagen | Blindness | Stem cells | Renal failure | Pericytes | Microvasculature | Pluripotency | Structure-function relationships
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2013, Volume 190, Issue 5, pp. 2036 - 2048
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2013, Volume 14, Issue 1, pp. 41 - 51
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2009, Volume 206, Issue 11, pp. 2455 - 2467
Journal Article
Brain Research, ISSN 0006-8993, 2015, Volume 1603, pp. 141 - 149
Abstract Our previous findings indicated that in rats subjected to subarachnoid hemorrhage (SAH), suppression of post-SAH neuroinflammation via vascular... 
Neurology | Cerebral vascular function | Neuroinflammation | Leukocyte adhesion | Stroke | Neurological outcome | Cerebral vascularfunction | ACTIVATION | VASOSPASM | INFLAMMATION | RATS | INNATE | INJURY | NEUROSCIENCES | Venules - physiopathology | Cerebrovascular Circulation - physiology | Pia Mater - drug effects | Cell Adhesion Molecules - antagonists & inhibitors | Male | Neuroimmunomodulation - physiology | Pia Mater - physiopathology | Venules - drug effects | Leukocytes - physiology | Neutrophil Infiltration - physiology | Regional Blood Flow - drug effects | Amine Oxidase (Copper-Containing) - antagonists & inhibitors | Arterioles - physiopathology | Allylamine - pharmacology | Subarachnoid Hemorrhage - mortality | Nitric Oxide Donors - pharmacology | Cholinergic Agonists - pharmacology | Neutrophil Infiltration - drug effects | Subarachnoid Hemorrhage - drug therapy | Disease Models, Animal | Acetylcholine - pharmacology | Cerebrovascular Circulation - drug effects | Neutrophils - drug effects | Allylamine - analogs & derivatives | Neutrophils - physiology | Pia Mater - blood supply | Arterioles - drug effects | Cell Adhesion Molecules - metabolism | Rats, Sprague-Dawley | Amine Oxidase (Copper-Containing) - metabolism | Cardiovascular Agents - pharmacology | Subarachnoid Hemorrhage - physiopathology | Animals | Leukocytes - drug effects | Regional Blood Flow - physiology | S-Nitroso-N-Acetylpenicillamine - pharmacology | Neuroimmunomodulation - drug effects | Prevention | Stroke (Disease) | Employee recruitment | Acetylcholine | Subarachnoid hemorrhage | Analysis
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2009, Volume 74, Issue 3, pp. 934 - 941
Purpose In this article, we investigate the role of tumor necrosis factor-alpha (TNF) in the initiation of acute damage to the blood-brain barrier (BBB) and... 
Radiology | Hematology, Oncology and Palliative Medicine | Astrogliosis | Blood-brain barrier | Radiation toxicity | Tumor necrosis factor | Vascular response | MOUSE-BRAIN | PERMEABILITY | ENDOTHELIAL CELL-ADHESION | NORMAL TISSUE | ALPHA | IRRADIATION | ONCOLOGY | LEUKOCYTE ADHESION | RAT-BRAIN | IONIZING-RADIATION | EXPRESSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Antibody Specificity | Fluorescein-5-isothiocyanate - pharmacokinetics | Arterioles - radiation effects | Cell Adhesion - radiation effects | Male | Venules - drug effects | Leukocytes - physiology | Venules - radiation effects | Central Nervous System Neoplasms - radiotherapy | Leukocytes - radiation effects | Dextrans - pharmacokinetics | Astrocytes - radiation effects | Brain - blood supply | Time Factors | Intercellular Adhesion Molecule-1 - radiation effects | Blood-Brain Barrier - physiology | Leukocyte Count | Astrocytes - drug effects | Arterioles - anatomy & histology | Permeability - drug effects | Venules - anatomy & histology | Mice, Inbred C57BL | Fluorescein-5-isothiocyanate - analogs & derivatives | Brain - radiation effects | Radiation Dosage | Recombinant Proteins - pharmacology | Cell Adhesion - drug effects | Cranial Irradiation | Arterioles - drug effects | Blood-Brain Barrier - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Intercellular Adhesion Molecule-1 - metabolism | Animals | Permeability - radiation effects | Fluorescent Antibody Technique | Tumor Necrosis Factor-alpha - physiology | Blood-Brain Barrier - radiation effects | Leukocytes - drug effects | Mice | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Radiation | Tumors | Arterioles | Index Medicus | ADHESION | LEUKOCYTES | NEOPLASMS | DEXTRAN | RADIOLOGY AND NUCLEAR MEDICINE | BLOOD-BRAIN BARRIER | MICE | TOXICITY | RADIOTHERAPY | CEREBRAL CORTEX | RADIATION INJURIES
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 05/2013, Volume 147, Issue 1, pp. 74 - 83
Chlorogenic acid (CA) exits widely in those Chinese herbal injections that have antibacterial and antiphlogistic effects and belongs to the... 
Reactive oxygen species | Chlorogenic acid | Safety | Mesenteric microcirculation | NADPH oxidase | MESENTERY | CHEMISTRY, MEDICINAL | HYDROXYCINNAMIC ACIDS | PHENOLIC-ACIDS | REPERFUSION | DAMAGE | PLANT SCIENCES | POLYPHENOLS | INTEGRATIVE & COMPLEMENTARY MEDICINE | DNA | ANTIOXIDANT | PHARMACOLOGY & PHARMACY | INDUCED MICROCIRCULATORY DISTURBANCE | Inflammation - pathology | Venules - physiopathology | Venules - immunology | Tumor Necrosis Factor-alpha - blood | NADPH Oxidases - metabolism | Capillary Permeability - drug effects | Male | Venules - drug effects | RNA, Messenger - metabolism | Chlorogenic Acid - toxicity | Inflammation - blood | Ileum - drug effects | Time Factors | NADPH Oxidases - genetics | Real-Time Polymerase Chain Reaction | Malondialdehyde - metabolism | Splanchnic Circulation - drug effects | Neutrophils - drug effects | Rats | Blotting, Western | Mesentery - blood supply | CD18 Antigens - metabolism | Leukocytes - drug effects | Oxidative Stress - drug effects | Serum Albumin - metabolism | Inflammation - chemically induced | Leukocyte Rolling - drug effects | Ileum - pathology | Catalase - blood | Rats, Wistar | Superoxide Dismutase - blood | Microscopy, Video | Ileum - immunology | Microcirculation - drug effects | Dose-Response Relationship, Drug | Leukocytes - immunology | Flow Cytometry | Interleukin-6 - blood | Mast Cells - immunology | Enzyme-Linked Immunosorbent Assay | Inflammation Mediators - blood | Neutrophils - immunology | Inflammation - immunology | NADPH Oxidase 4 | Mast Cells - drug effects | Gene Expression Regulation, Enzymologic | Venules - metabolism | Animals | Inflammation - genetics | CD11b Antigen - metabolism | Cell Degranulation - drug effects | Inflammation - physiopathology | Peroxidase - metabolism | Oxidases
Journal Article
Journal Article
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 2010, Volume 130, Issue 2, pp. 398 - 406
Cerebralcare Granule (CG) is a Chinese herb compound preparation that has been used for treatment of cerebrovascular related diseases. However, the effect of... 
Global ischemia | Chinese medicine | Cerebral microcirculatory disturbance | Hippocampal neuron injury | Apoptosis | CHEMISTRY, MEDICINAL | CASSIA-TORA | INHIBITORY-ACTIVITY | DRUG DISCOVERY | RAT MESENTERY | BRAIN-DAMAGE | DISTURBANCE | PLANT SCIENCES | STROKE | IN-VITRO | INTEGRATIVE & COMPLEMENTARY MEDICINE | INDUCED MICROVASCULAR DYSFUNCTION | PHARMACOLOGY & PHARMACY | CONSTITUENTS | Leukocyte Rolling - drug effects | Reperfusion Injury - etiology | Venules - physiopathology | Capillary Permeability | Cerebral Veins - metabolism | Apoptosis - drug effects | Caspase 3 - metabolism | Reperfusion Injury - drug therapy | Drugs, Chinese Herbal - pharmacology | Male | Venules - drug effects | Microcirculation - drug effects | CA1 Region, Hippocampal - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Neurons - ultrastructure | Neuroprotective Agents - pharmacology | CA1 Region, Hippocampal - metabolism | Neurons - metabolism | Drugs, Chinese Herbal - administration & dosage | Neurons - drug effects | Neuroprotective Agents - administration & dosage | CA1 Region, Hippocampal - ultrastructure | Disease Models, Animal | Brain Ischemia - complications | Cardiovascular Agents - administration & dosage | Cerebral Veins - drug effects | Reperfusion Injury - pathology | Cerebrovascular Circulation - drug effects | bcl-2-Associated X Protein - metabolism | Brain Ischemia - physiopathology | Cardiovascular Agents - pharmacology | Hydrogen Peroxide - metabolism | Venules - metabolism | Animals | Cerebral Veins - physiopathology | Gerbillinae | Brain Ischemia - drug therapy | Brain Ischemia - pathology | Reperfusion Injury - physiopathology | Serum Albumin - metabolism
Journal Article