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Journal Article
Water Research, ISSN 0043-1354, 2011, Volume 45, Issue 11, pp. 3417 - 3426
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 50, pp. 20412 - 20424
Journal Article
Journal of Chromatography B, ISSN 1570-0232, 2007, Volume 847, Issue 2, pp. 174 - 181
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2012, Volume 418, Issue 1, pp. 161 - 166
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Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 02/2014, Volume 22, Issue 3, pp. 1148 - 1155
Natural products represent the fourth generation of multidrug resistance (MDR) reversal agents that resensitize MDR cancer cells overexpressing P-glycoprotein... 
P-glycoprotein | ABCB1 | Multidrug resistance | Docking | Strychnos alkaloids | Total synthesis | Resensitization | CHEMISTRY, MEDICINAL | MEDIATED MULTIDRUG-RESISTANCE | TRANSPORTERS | NATURAL-PRODUCTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | REDUCTION | ONCOLOGY | ACCURATE DOCKING | (-)-TUBIFOLIDINE | CYTOTOXICITY | VERAPAMIL | AMIDES | Tubocurarine - analogs & derivatives | Drug Resistance, Multiple - drug effects | Humans | Indoles - chemical synthesis | Tubocurarine - chemistry | Alkaloids - chemical synthesis | Cell Line, Tumor - drug effects | Heterocyclic Compounds, 4 or More Rings - chemical synthesis | Strychnos - chemistry | Heterocyclic Compounds, 4 or More Rings - pharmacology | Tubocurarine - pharmacology | Indole Alkaloids - chemical synthesis | Indoles - pharmacology | Indole Alkaloids - chemistry | ATP Binding Cassette Transporter, Subfamily B, Member 1 - chemistry | Tubocurarine - chemical synthesis | Alkaloids - pharmacology | Antineoplastic Agents, Phytogenic - chemical synthesis | Chemistry Techniques, Synthetic | Heterocyclic Compounds, 4 or More Rings - chemistry | Adenosine Triphosphatases - metabolism | Antineoplastic Agents, Phytogenic - chemistry | Verapamil - pharmacology | ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Indole Alkaloids - pharmacology | Protein Conformation | Molecular Docking Simulation | Antineoplastic Agents, Phytogenic - pharmacology | Indoles - chemistry | Alkaloids - chemistry | Drug Resistance, Neoplasm - drug effects | Drug Screening Assays, Antitumor
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 01/2015, Volume 478, Issue 2, pp. 617 - 624
Journal Article
Biochemistry, ISSN 0006-2960, 04/2017, Volume 56, Issue 13, pp. 1921 - 1931
Resistance to the anticancer antibiotics, doxorubicin and daunorubicin, in the producer organism Streptomyces peucetius is conferred by an ABC transporter made... 
ABC TRANSPORTER | MULTIDRUG EFFLUX PUMP | DRUG-BINDING | BROAD SUBSTRATE-SPECIFICITY | STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | TRANSPORTER P-GLYCOPROTEIN | PREDICTED TRANSMEMBRANE DOMAIN | ATP-BINDING | FUNCTIONAL CONSEQUENCES | Ethidium - chemistry | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Bacterial Proteins - chemistry | Substrate Specificity | Ethidium - metabolism | Doxorubicin - chemistry | Benzimidazoles - chemistry | Streptomyces - metabolism | ATP-Binding Cassette Transporters - chemistry | ATP-Binding Cassette Transporters - genetics | Escherichia coli - metabolism | ATP-Binding Cassette Transporters - metabolism | ATP-Binding Cassette, Sub-Family B, Member 1 - chemistry | Doxorubicin - metabolism | Daunorubicin - metabolism | Recombinant Proteins - metabolism | Gene Expression | Protein Structure, Secondary | Streptomyces - genetics | Bacterial Proteins - genetics | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Static Electricity | Daunorubicin - chemistry | Verapamil - chemistry | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Escherichia coli - genetics | Benzimidazoles - metabolism | Protein Binding | Bacterial Proteins - metabolism | Structural Homology, Protein | Mutation | Drug Resistance, Multiple, Bacterial - genetics | Verapamil - metabolism | Evolution, Molecular | Chemical bonds | Chemical reactions | Usage | Analysis
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