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Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2009, Volume 52, Issue 14, pp. 4400 - 4418
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 02/2013, Volume 166, Issue 1, pp. 1 - 9
Ovarian cancer is the most lethal gynecological malignancy, characterized by a high rate of chemoresistance. Current treatment strategies for ovarian cancer... 
Bioluminescence imaging | PET imaging | Polymeric micelles | Paclitaxel | Combination drug delivery | Ovarian cancer | SYSTEM | CELLS | EFFICACY | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | THERAPY | INHIBITION | RESISTANCE | PHARMACOLOGY & PHARMACY | Veratrum Alkaloids - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Gossypol - therapeutic use | Paclitaxel - pharmacology | Antineoplastic Combined Chemotherapy Protocols - chemistry | Humans | Ovarian Neoplasms - pathology | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Paclitaxel - chemistry | Micelles | Surface Properties | Veratrum Alkaloids - pharmacology | Female | Paclitaxel - administration & dosage | Ovarian Neoplasms - drug therapy | Lactones - chemistry | Cell Survival - drug effects | Veratrum Alkaloids - therapeutic use | Injections, Intraperitoneal | Kaplan-Meier Estimate | Solubility | Treatment Outcome | Paclitaxel - therapeutic use | Veratrum Alkaloids - chemistry | Xenograft Model Antitumor Assays | Gossypol - pharmacology | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Cell Line, Tumor | Mice | Gossypol - chemistry | Gossypol - administration & dosage | Drugs | Ethylene glycol | Drug delivery systems | Polyethylene | Care and treatment | Models | Drug therapy, Combination | Gossypol | Cancer | Vehicles | Index Medicus | paclitaxel | polymeric micelles | combination drug delivery | ovarian cancer
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 10/2016, Volume 26, Issue 19, pp. 4735 - 4738
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 2015, Volume 17, Issue 1, pp. 57 - 67
Journal Article
Science, ISSN 0036-8075, 10/2009, Volume 326, Issue 5952, pp. 572 - 574
The Hedgehog (Hh) signaling pathway is inappropriately activated in certain human cancers, including medulloblastoma, an aggressive brain tumor. GDC-0449, a... 
Receptors | Relapse | Basal cell carcinoma | Medulloblastoma | Amino acids | Biopsies | Reports | Genetic mutation | Tumors | Resistance mechanisms | Cancer | PROTEIN-COUPLED RECEPTORS | CYCLOPAMINE | CANCER | MULTIDISCIPLINARY SCIENCES | Anilides - therapeutic use | Receptors, G-Protein-Coupled - metabolism | Humans | Brain Neoplasms - pathology | Hedgehog Proteins - metabolism | Molecular Sequence Data | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Mutation, Missense | Antineoplastic Agents - metabolism | Neoplasm Metastasis | Hedgehog Proteins - genetics | Medulloblastoma - pathology | Smoothened Receptor | Veratrum Alkaloids - pharmacology | Antineoplastic Agents - pharmacology | Patched Receptors | Medulloblastoma - genetics | Mutant Proteins - antagonists & inhibitors | Pyridines - therapeutic use | Amino Acid Sequence | Signal Transduction | Anilides - metabolism | Brain Neoplasms - genetics | Receptors, Cell Surface - metabolism | Mutant Proteins - metabolism | Hedgehog Proteins - antagonists & inhibitors | Brain Neoplasms - drug therapy | Cinnamates - pharmacology | Animals | Pyridines - metabolism | Mutant Proteins - chemistry | Anilides - pharmacology | Receptors, G-Protein-Coupled - antagonists & inhibitors | Cell Line, Tumor | Protein Conformation | Mice | Pyridines - pharmacology | Receptors, G-Protein-Coupled - genetics | Medulloblastoma - drug therapy | Receptors, G-Protein-Coupled - chemistry | Amino Acid Substitution | Receptors, Cell Surface - genetics | Gene mutations | Development and progression | Genetic aspects | Diagnosis | Drug resistance | Identification and classification | Signal transduction | Genotype & phenotype | Inhibitor drugs | Cellular biology | Brain cancer | Mutation | Index Medicus
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 04/2009, Volume 458, Issue 7239, pp. 776 - 779
Journal Article
Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6063, pp. 1727 - 1731
Journal Article