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vesicular transport proteins (41) 41
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Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5998, pp. 1530 - 1534
Endosomal Toll-like receptors (TLRs) 7 and 9 recognize viral pathogens and induce signals leading to the activation of nuclear factor KB (NF-KB)-dependent... 
T lymphocytes | Molecules | Cytokines | Microscopy | Genes | REPORTS | Toll like receptors | Agonists | Macrophages | Cells | Endosomes | LOCALIZATION | ACTIVATION | DENDRITIC CELLS | TRAF3 | MULTIDISCIPLINARY SCIENCES | TLR9 | TOLL-LIKE-RECEPTOR-9 | INDUCTION | INTERFERON-ALPHA PRODUCTION | I INTERFERON | AP-3 ADAPTER | Recombinant Fusion Proteins - immunology | Dendritic Cells - immunology | Transcriptional Activation | Interferon Type I - immunology | Recombinant Fusion Proteins - metabolism | Endosomes - metabolism | Toll-Like Receptor 9 - immunology | Cytoplasmic Vesicles - metabolism | Interferon Type I - metabolism | Membrane Transport Proteins - metabolism | Cytokines - genetics | Dendritic Cells - metabolism | Macrophages - immunology | Cytokines - immunology | Oligodeoxyribonucleotides - immunology | Cytokines - metabolism | Signal Transduction | Vesicle-Associated Membrane Protein 3 - metabolism | Mice, Inbred C57BL | Cells, Cultured | TNF Receptor-Associated Factor 3 - metabolism | Adaptor Protein Complex beta Subunits | Interferon Regulatory Factor-7 - metabolism | Adaptor Protein Complex 3 - metabolism | Protein Transport | Animals | Adaptor Protein Complex 3 - genetics | Interferon Type I - genetics | Mice | Toll-Like Receptor 9 - metabolism | Myeloid Differentiation Factor 88 - metabolism | Lysosomal-Associated Membrane Protein 2 - metabolism | Cellular control mechanisms | Physiological aspects | TLR7 | Research | Health aspects | Immune system | Proteins | Signal transduction | Interferon | Cellular biology | Receptors | Compartments | Bifurcations | Activation
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2011, Volume 108, Issue 34, pp. 14318 - 14323
Exocytosis of synaptic vesicles (SVs) during fast synaptic transmission is mediated by soluble N-ethylmaleimide-sensitive factor attachment protein receptor... 
Molecules | Histograms | Neurons | Bleaching | Synaptic transmission | SNARE proteins | Fluorescence | Recycling | Exocytosis | Synapses | Membrane fusion | SynaptopHluorin | Single molecule bleaching | SNARE density | CELLS | SECRETORY VESICLES | MULTIDISCIPLINARY SCIENCES | single molecule bleaching | SYNAPTIC-TRANSMISSION | ENERGETICS | 3 SNARE COMPLEXES | CA2+-TRIGGERED EXOCYTOSIS | synaptopHluorin | ENDOCYTOSIS | membrane fusion | HIPPOCAMPAL SYNAPSES | MEMBRANE-FUSION | PROTEINS | Green Fluorescent Proteins - metabolism | Synaptic Vesicles - metabolism | Calcium - pharmacology | Central Nervous System - metabolism | Vesicle-Associated Membrane Protein 3 - metabolism | Mice, Inbred C57BL | Vesicle-Associated Membrane Protein 2 - deficiency | Neurons - cytology | Hippocampus - cytology | Recombinant Fusion Proteins - metabolism | Exocytosis - drug effects | Mice, Knockout | Gene Dosage - drug effects | Animals | Central Nervous System - drug effects | Synaptic Vesicles - drug effects | Synaptic Transmission - drug effects | Mice | Neurons - metabolism | Vesicle-Associated Membrane Protein 3 - deficiency | Neurons - drug effects | Vesicle-Associated Membrane Protein 2 - metabolism | Membrane Fusion - drug effects | Physiological aspects | Health aspects | Central nervous system | Membrane proteins | Biological Sciences
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 04/2016, Volume 18, Issue 4, pp. 355 - 365
Aim: To determine the impact of a functional human islet clock on insulin secretion and gene transcription. Methods: Efficient circadian clock disruption was... 
human pancreatic islet | circadian bioluminescence | insulin secretion | RNA | circadian clock | sequencing | Circadian clock | RNA sequencing | Circadian bioluminescence | Human pancreatic islet | Insulin secretion | PERIPHERAL CLOCKS | SYSTEM | TRANSCRIPTOME | BEHAVIOR | BETA-CELLS | METABOLISM | CHANNEL | GENES | ENDOCRINOLOGY & METABOLISM | OSCILLATIONS | EXPRESSION | Islets of Langerhans - drug effects | Sodium-Potassium-Exchanging ATPase - genetics | Cation Transport Proteins - antagonists & inhibitors | Sodium-Potassium-Exchanging ATPase - chemistry | Zinc Transporter 8 | Humans | CLOCK Proteins - genetics | Gene Expression Profiling | Potassium Channels, Inwardly Rectifying - chemistry | Qa-SNARE Proteins - chemistry | CLOCK Proteins - metabolism | Insulin-Secreting Cells - metabolism | Vesicle-Associated Membrane Protein 3 - chemistry | GTP-Binding Protein alpha Subunits, Gq-G11 - chemistry | RNA Interference | Cation Transport Proteins - metabolism | Islets of Langerhans - metabolism | Islets of Langerhans - cytology | Qa-SNARE Proteins - genetics | Cation Transport Proteins - genetics | Potassium Channels, Inwardly Rectifying - antagonists & inhibitors | Insulin-Secreting Cells - cytology | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Insulin Secretion | Vesicle-Associated Membrane Protein 3 - antagonists & inhibitors | Vesicle-Associated Membrane Protein 3 - genetics | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors | Circadian Clocks - drug effects | Colforsin - pharmacology | Vesicle-Associated Membrane Protein 3 - metabolism | CLOCK Proteins - antagonists & inhibitors | Cells, Cultured | GTP-Binding Protein alpha Subunits, Gq-G11 - antagonists & inhibitors | Potassium Channels, Inwardly Rectifying - genetics | Gene Expression Regulation - drug effects | Hyperglycemia - metabolism | Sodium-Potassium-Exchanging ATPase - metabolism | Insulin - metabolism | Insulin-Secreting Cells - drug effects | Qa-SNARE Proteins - metabolism | Genes, Reporter - drug effects | Qa-SNARE Proteins - antagonists & inhibitors | RNA, Small Interfering | Cation Transport Proteins - chemistry | Potassium Channels, Inwardly Rectifying - metabolism | Pancreatic beta cells | Analysis | Glucose | Insulin | Dextrose | Circadian rhythm | Pancreas | Rodents | Circadian rhythms | Transcription | Secretion | Islet cells | siRNA | Islets of Langerhans | Gene expression
Journal Article
Journal Article
European Journal of Immunology, ISSN 0014-2980, 03/2008, Volume 38, Issue 3, pp. 855 - 863
Mediator release from mast cells (MC) is a crucial step in allergic and non-allergic inflammatory disorders. However, the final events in response to... 
Allergology | Cellular immunology | Mast cells | Mucosal immunity | FUSION | INVOLVEMENT | IMMUNOLOGY | mast cells | COMPOUND EXOCYTOSIS | IDENTIFICATION | cellular immunology | MEDIATOR RELEASE | HUMAN EOSINOPHILS | allergology | SNARE COMPLEXES | SNAP-23 | RECEPTORS | EXPRESSION | mucosal immunity | Gene Expression - drug effects | SNARE Proteins - genetics | Humans | Qb-SNARE Proteins - metabolism | R-SNARE Proteins - metabolism | Qb-SNARE Proteins - genetics | Cytoplasm - metabolism | Qc-SNARE Proteins - immunology | Vesicle-Associated Membrane Protein 2 - physiology | Vesicle-Associated Membrane Protein 2 - genetics | Vesicle-Associated Membrane Protein 3 - physiology | Qc-SNARE Proteins - metabolism | Mast Cells - metabolism | Qa-SNARE Proteins - genetics | Cell Membrane - metabolism | Histamine Release - drug effects | Vesicle-Associated Membrane Protein 3 - genetics | R-SNARE Proteins - genetics | Vesicle-Associated Membrane Protein 3 - metabolism | Histamine Release - physiology | Mast Cells - physiology | Tetanus Toxin - pharmacology | Qa-SNARE Proteins - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mast Cells - drug effects | Blotting, Western | Antibodies - pharmacology | R-SNARE Proteins - physiology | Metalloendopeptidases - pharmacology | Qa-SNARE Proteins - metabolism | Fluorescent Antibody Technique | Qb-SNARE Proteins - immunology | Qc-SNARE Proteins - genetics | Vesicle-Associated Membrane Protein 2 - metabolism | SNARE Proteins - metabolism | Cell Degranulation - physiology | Cell Degranulation - drug effects | Index Medicus | Qb-SNARE Proteins | Cell Membrane | Vesicle-Associated Membrane Protein 2 | Gene Expression | Vesicle-Associated Membrane Protein 3 | Cell Degranulation | Tetanus Toxin | R-SNARE Proteins | Antibodies | Metalloendopeptidases | Life Sciences | Immunology | Qa-SNARE Proteins | Qc-SNARE Proteins | Histamine Release | SNARE Proteins | Cytoplasm | Mast Cells
Journal Article
PLoS Genetics, ISSN 1553-7390, 04/2017, Volume 13, Issue 4, p. e1006698
The cellular machinery required for the fusion of constitutive secretory vesicles with the plasma membrane in metazoans remains poorly defined. To address this... 
CELLS | CYTOKINE SECRETION | SNARE COMPLEX | EXOCYTOSIS | PATHWAY | GENETICS & HEREDITY | GOLGI TRANSPORT | VAMP FAMILY | ENDOPLASMIC-RETICULUM | SYNTAXIN | SYNAPTIC VESICLE PROTEINS | Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins - genetics | R-SNARE Proteins - genetics | SNARE Proteins - genetics | Vesicle-Associated Membrane Protein 3 - metabolism | Humans | R-SNARE Proteins - metabolism | Membrane Fusion - genetics | Shiga Toxin 1 - metabolism | Cell Membrane - genetics | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Protein Transport - genetics | Drosophila melanogaster - metabolism | Animals | RNA Interference | Golgi Apparatus - metabolism | Heterozygote | Cell Membrane - metabolism | Drosophila Proteins - genetics | SNARE Proteins - metabolism | Shiga Toxin 1 - genetics | Golgi Apparatus - genetics | Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins - metabolism | Vesicle-Associated Membrane Protein 3 - genetics | Physiological aspects | Genetic aspects | Cell membranes | Research | Gene expression | Drosophila | Medical research | Cytokines | Lipids | Genomes | Biology | Cell fusion | Ribonucleic acid--RNA | Machinery | Studies | Proteins | Molecular evolution | Cell growth | Secretory vesicles | Eukaryotes | Depletion | Insects | Plasma membranes | Extracellular matrix | Physiology | Endoplasmic reticulum | Combinatorial analysis | Plasmas (physics) | RNA | Ribonucleic acid
Journal Article
Journal of cell science, ISSN 0021-9533, 08/2015, Volume 128, Issue 15, pp. 2891 - 2902
Journal Article
FEBS Journal, ISSN 1742-464X, 2014, Volume 281, Issue 3, pp. 750 - 765
Fibroblast-like synoviocytes are important mediators of inflammatory joint damage in arthritis through the release of cytokines, but it is unknown whether... 
TNFα | Arthritis | SW982 | SNAREs | IL-6 | RHEUMATOID-ARTHRITIS | CYTOKINE SECRETION | TOXIN-A | TNF alpha | PROTEIN | BOTULINUM-NEUROTOXIN-A | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN SYNOVIOCYTES | SENSORY NEURONS | MEMBRANE-FUSION | arthritis | JOINT PAIN | CLOSTRIDIAL NEUROTOXINS | Arthritis - metabolism | Membrane Glycoproteins - metabolism | Humans | Qb-SNARE Proteins - metabolism | Qb-SNARE Proteins - genetics | Synovial Membrane - immunology | Protein Transport - drug effects | Synovial Membrane - drug effects | Molecular Targeted Therapy | Exocytosis - drug effects | Membrane Glycoproteins - antagonists & inhibitors | Protein Isoforms - metabolism | Qc-SNARE Proteins - metabolism | RNA Interference | Interleukin-1beta - metabolism | Anti-Inflammatory Agents - therapeutic use | Arthritis - immunology | Qa-SNARE Proteins - genetics | Vesicle-Associated Membrane Protein 3 - antagonists & inhibitors | Vesicle-Associated Membrane Protein 3 - genetics | Nerve Tissue Proteins - antagonists & inhibitors | Anti-Inflammatory Agents - pharmacology | Vesicle-Associated Membrane Protein 3 - metabolism | Tumor Necrosis Factor-alpha - secretion | Interleukin-6 - secretion | Nerve Tissue Proteins - genetics | Synovial Membrane - metabolism | Membrane Glycoproteins - genetics | Receptors, Interleukin-1 - metabolism | Nerve Tissue Proteins - metabolism | Synovial Membrane - secretion | Calcium Signaling - drug effects | Qa-SNARE Proteins - metabolism | Arthritis - drug therapy | Cell Line, Tumor | Qc-SNARE Proteins - genetics | Qa-SNARE Proteins - antagonists & inhibitors | Qc-SNARE Proteins - antagonists & inhibitors | RNA, Small Interfering | Qb-SNARE Proteins - antagonists & inhibitors | Protein Isoforms - antagonists & inhibitors | Protein Isoforms - genetics
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2012, Volume 287, Issue 44, pp. 37530 - 37539
Journal Article