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PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 9, p. e106543
NK-lysin is an antimicrobial protein produced by cytotoxic T lymphocytes and natural killer cells. In this study, we examined the biological property of a... 
CELLS | DEFENSE | CYNOGLOSSUS-SEMILAEVIS | MULTIDISCIPLINARY SCIENCES | ANTIMICROBIAL PEPTIDE | INNATE | FISH | SYNTHETIC PEPTIDE | IDENTIFICATION | EXPRESSION | GRANULYSIN | Antimicrobial Cationic Peptides - immunology | DNA, Bacterial - metabolism | Streptococcal Infections - veterinary | Molecular Sequence Data | Flatfishes - genetics | Vibrio Infections - immunology | Antimicrobial Cationic Peptides - administration & dosage | Host-Pathogen Interactions - immunology | Vibrio - metabolism | Streptococcal Infections - genetics | Fish Proteins - genetics | Bacterial Infections - genetics | Vibrio Infections - genetics | Proteolipids - immunology | Bacterial Infections - immunology | Fish Diseases - immunology | Antimicrobial Cationic Peptides - genetics | Virus Diseases - genetics | Vibrio Infections - veterinary | Amino Acid Sequence | Proteolipids - administration & dosage | Gene Expression | Fish Diseases - microbiology | Proteolipids - genetics | Virus Diseases - immunology | Fish Proteins - immunology | Flatfishes - immunology | Pseudomonas fluorescens | Bacterial Infections - veterinary | Fish Proteins - administration & dosage | Pseudomonas Infections - genetics | Pseudomonas Infections - immunology | Sequence Homology, Amino Acid | Pseudomonas Infections - veterinary | Animals | Fish Diseases - virology | Host-Pathogen Interactions - genetics | Virus Diseases - veterinary | Streptococcal Infections - immunology | Vibrio - pathogenicity | Peptides | DNA | Aquaculture industry | Fishes | Bacteria | Bacterial genetics | Health aspects | Biological properties | Laboratories | Gram-positive bacteria | Cytotoxicity | Amino acids | Lymphocytes T | Infections | Antiinfectives and antibacterials | Degradation | Killer cells | Clonal deletion | E coli | Lymphocytes | Animal tissues | Antimicrobial peptides | Fish | Natural killer cells | Deoxyribonucleic acid--DNA | Immune system | Biodegradation | Pathogens | Immune response | Staphylococcus infections | Marine biology | Antimicrobial agents | Gene expression | Bactericidal activity | In vivo methods and tests | Cytoplasm | Viral infections | Aquaculture | Deoxyribonucleic acid
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 11, p. e50263
Piscidins are antimicrobial peptides (AMPs) that play important roles in helping fish resist pathogenic infections... 
HOST-DEFENSE PEPTIDES | IMMUNE-RESPONSE | CANDIDA-ALBICANS | MULTIDISCIPLINARY SCIENCES | MAST-CELLS | GENE-EXPRESSION | FISH | ALPHA | HYBRID STRIPED BASS | ANTIMICROBIAL PEPTIDES | EPINECIDIN-1 | Spleen - immunology | Open Reading Frames | Gills - microbiology | Streptococcal Infections - veterinary | Molecular Sequence Data | Gills - immunology | Fish Proteins - isolation & purification | Vibrio Infections - immunology | Cichlids - genetics | Ovary - cytology | Fish Proteins - pharmacology | Spleen - microbiology | Fish Proteins - genetics | RNA, Messenger - biosynthesis | Vibrio Infections - microbiology | Fish Diseases - immunology | Female | Ovary - drug effects | Antimicrobial Cationic Peptides - genetics | Vibrio Infections - veterinary | Vibrio vulnificus - growth & development | Expressed Sequence Tags | Amino Acid Sequence | Streptococcal Infections - microbiology | Fish Diseases - microbiology | RNA, Messenger - genetics | Antimicrobial Cationic Peptides - pharmacology | Cells, Cultured | Gene Expression Regulation | Cichlids - immunology | Streptococcus agalactiae - growth & development | Fish Diseases - genetics | Animals | Antimicrobial Cationic Peptides - isolation & purification | Cell Proliferation - drug effects | Cichlids - microbiology | Streptococcal Infections - immunology | Peptides | RNA | Health aspects | Analysis | Fishes | Water-borne diseases | Cell proliferation | Transcription | Liver | Genomics | Amino acids | Stimulation | Biology | Tissue analysis | Drug development | Antiinfectives and antibacterials | Synthesis | Coding | Antimicrobial peptides | Bacteria | Fish | Cod | Bass | Spleen | Kidneys | Bacterial infections | Research & development--R&D | Cationic peptides | Cloning | Gills | Staphylococcus infections | Tilapia | Antimicrobial agents | Injection | Gene expression | Polymerase chain reaction | Oreochromis niloticus | Skin | Aquaculture | Vibrio | Research & development | R&D
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e18832
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 3, p. e17629
Infection with Edwardsiella tarda, a Gram-negative bacterium, causes high morbidity and mortality in both marine and freshwater fish... 
JAPANESE FLOUNDER | PROTEIN-A | PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | NEISSERIA-MENINGITIDIS | RELEASE | SECRETION | TARDA | CELL | VIBRIO-CHOLERAE | Enterobacteriaceae Infections - prevention & control | Cell Membrane Structures - immunology | Enterobacteriaceae Infections - immunology | Flounder - microbiology | Spectrometry, Mass, Electrospray Ionization | Protective Agents - pharmacology | Fish Diseases - immunology | Edwardsiella tarda - immunology | Edwardsiella tarda - drug effects | Flounder - immunology | Immunization | Fish Diseases - microbiology | Cell Membrane Structures - drug effects | Enterobacteriaceae Infections - veterinary | Electrophoresis, Polyacrylamide Gel | Enterobacteriaceae Infections - microbiology | Toll-Like Receptors - immunology | Fish Diseases - prevention & control | Cell Membrane Structures - ultrastructure | Injections | Animals | Bacterial Vaccines - immunology | Proteomics | Survival Analysis | Bacterial Proteins - metabolism | Cytokines - biosynthesis | Proteins | Fishes | Bacteria | Hostages | Vaccines | Health aspects | Formaldehyde | Pilin | Veterinary colleges | Biotechnology | Pathogenesis | Virulence | Flagellin | Genomes | Infections | Veterinary medicine | Composition effects | Interleukin 6 | Vesicles | Databases | E coli | Virulence factors | Rodents | Phylogenetics | Fish | Freshwater fish | Gram-negative bacteria | Localization | Enzymes | Immune response | Immunostimulation | Bacterial infections | Prokaryotes | Trout | Membrane vesicles | Tumor necrosis factor-α | Morbidity | γ-Interferon | Information storage | Glyceraldehyde-3-phosphate dehydrogenase
Journal Article
Journal Article
Journal Article
Autophagy, ISSN 1554-8627, 03/2015, Volume 11, Issue 3, pp. 516 - 526
.... We show for the first time that autophagy pathway is present and functional in Pacific oysters and plays an important role to protect animals from infections... 
Pacific oyster | autophagy | Atg8-PE, Atg8-phosphatidylethenolamine | MAP1LC3A/B (LC3A/B), microtubule-associated proteins 1 light chain 3 alpha/beta (mammalian orthologs of the predicted Crassostrea gigas LC3 and yeast Atg8) | ATG, autophagy-related | Vibrio aestuarianus | OsHV-1, Ostreid herpesvirus 1 | LC3-II, cleaved, lipidated and autophagosome-associated form of LC3 | OsHV-1 | hpi, hours postinfection | PCR, polymerase chain reaction | DNA, deoxyribonucleic acid | Cl, ammonium chloride | Crassostrea gigas | Autophagy | MORTALITY | lipidated and autophagosome-associated form of LC3 | GUIDELINES | LC3-II | CELL BIOLOGY | MAP1LC3A | deoxyribonucleic acid | autophagy-related | STRESS | Atg8-phosphatidylethenolamine | microtubule-associated proteins 1 light chain 3 alpha | polymerase chain reaction | hpi | cleaved | B (LC3A | CRASSOSTREA-GIGAS | QUANTIFICATION | hours postinfection | ADAPTATIONS | beta (mammalian orthologs of the predicted Crassostrea gigas LC3 and yeast Atg8) | IDENTIFICATION | NH4Cl | Ostreid herpesvirus 1 | REAL-TIME PCR | Atg8-PE | ATG | ammonium chloride | DNA | MONITORING AUTOPHAGY | PCR | OSTREID HERPESVIRUS-1 | Amino Acid Sequence | Microscopy, Electron, Transmission | Herpesviridae - pathogenicity | Virus Diseases - immunology | Signal Transduction | DNA, Viral - isolation & purification | Gene Expression Regulation | Molecular Sequence Data | Phylogeny | Immunity, Innate | Bacterial Infections - veterinary | Crassostrea - immunology | Animals | Bacterial Infections - immunology | Crassostrea - virology | Crassostrea - microbiology | Virus Diseases - veterinary | Vibrio - pathogenicity | Real-Time Polymerase Chain Reaction | Aquaculture
Journal Article