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Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 10/2017, Volume 58, Issue 12, pp. 5043 - 5055
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2010, Volume 12, Issue 3, pp. 247 - 256
MicroRNAs (miRNAs) are increasingly implicated in regulating the malignant progression of cancer. Here we show that miR-9, which is upregulated in breast... 
ADHESION | STEM-CELLS | INVASION | N-MYC | C-MYC | TUMOR ANGIOGENESIS | HUMAN BREAST-CANCER | MESENCHYMAL TRANSITION | EXPRESSION | MAMMARY EPITHELIAL-CELLS | CELL BIOLOGY | Oncogene Proteins - genetics | RNA, Small Interfering - genetics | Protein Binding - genetics | Cell Proliferation | MicroRNAs - antagonists & inhibitors | Cadherins - metabolism | Gene Expression - genetics | Humans | 3' Untranslated Regions - genetics | Vascular Endothelial Growth Factor A - genetics | N-Myc Proto-Oncogene Protein | Cadherins - genetics | Oncogene Proteins - metabolism | Vascular Endothelial Growth Factor A - blood | Epithelial Cells - pathology | DNA - metabolism | Neuroblastoma - diagnosis | beta Catenin - metabolism | Down-Regulation - genetics | Cell Line, Tumor | Mice, Inbred NOD | Mice | Mice, Inbred BALB C | Neovascularization, Pathologic - metabolism | Neuroblastoma - metabolism | Proto-Oncogene Proteins c-myc - genetics | Histones - metabolism | MicroRNAs - physiology | Neoplasms - metabolism | Epithelial Cells - metabolism | Vimentin - metabolism | Lung Neoplasms - pathology | Breast Neoplasms - metabolism | Neovascularization, Pathologic - pathology | Neoplasms - blood | Transfection | Lung Neoplasms - secondary | Neoplasm Invasiveness - pathology | Female | Nuclear Proteins - genetics | Gene Expression Regulation, Neoplastic - physiology | Neuroblastoma - pathology | Cell Line | Neuroblastoma - genetics | Nuclear Proteins - metabolism | Gene Dosage | Mice, SCID | Proto-Oncogene Proteins c-myc - metabolism | beta Catenin - genetics | Neoplasm Metastasis - genetics | Animals | Breast Neoplasms - pathology | Neoplasm Metastasis - pathology | Signal Transduction - physiology | Transplantation, Heterologous - pathology | Neoplasm Invasiveness - genetics | Neoplasms - pathology | MicroRNA | Physiological aspects | Cadherins | Development and progression | Genetic aspects | Metastasis | Research | Oncogenes | Index Medicus
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 9/1999, Volume 146, Issue 6, pp. 1239 - 1254
Formation of a novel structure, the aggresome, has been proposed to represent a general cellular response to the presence of misfolded proteins (Johnston,... 
COS cells | Vimentin | Transfection | Ubiquitins | Microtubules | Antibodies | Cell aggregates | Chimeras | Cells | Microtubule organizing center | Aggresome | Chaperones | p50/dynamitin | Proteasome | proteasome | CELLS | MEMBRANE-PROTEIN | ORNITHINE DECARBOXYLASE | microtubules | QUALITY-CONTROL | CELL BIOLOGY | GREEN FLUORESCENT PROTEIN | PATHWAY | VIRUS G-PROTEIN | GOLGI TRANSPORT | DEGRADATION | ENDOPLASMIC-RETICULUM | chaperones | aggresome | Organelles - chemistry | Green Fluorescent Proteins | Molecular Chaperones - metabolism | Multienzyme Complexes - metabolism | Proteasome Endopeptidase Complex | Microtubules - metabolism | Organelles - ultrastructure | Biological Transport | Membrane Glycoproteins | Peptide Fragments - genetics | Ubiquitins - metabolism | Dyneins - metabolism | Viral Envelope Proteins - genetics | Membrane Proteins - genetics | Cytosol - ultrastructure | Solubility | Dynactin Complex | Recombinant Fusion Proteins - chemistry | Cytosol - chemistry | Peptide Fragments - chemistry | Recombinant Fusion Proteins - genetics | Cytosol - metabolism | Luminescent Proteins - genetics | Protein Processing, Post-Translational | Kinetics | COS Cells | Organelles - metabolism | Microtubule-Associated Proteins - metabolism | Vimentin - metabolism | Endoplasmic Reticulum - metabolism | Golgi Matrix Proteins | Recombinant Fusion Proteins - metabolism | Centrosome - ultrastructure | Cysteine Endopeptidases - metabolism | Viral Envelope Proteins - metabolism | Carrier Proteins - chemistry | Membrane Proteins - metabolism | Vesicular Transport Proteins | Peptide Fragments - metabolism | Microtubule-Associated Proteins - antagonists & inhibitors | Protein Folding | Centrosome - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Membrane Proteins - chemistry | Dyneins - antagonists & inhibitors | Golgi Apparatus - metabolism | Luminescent Proteins - metabolism | Protein folding | Cell organelles | Research | Proteins | Cellular biology | Enzymes | Index Medicus | p50 | dynamitin | Original
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 03/2011, Volume 15, Issue 3, pp. 635 - 646
Tumour‐associated fibroblasts (TAFs) are part of the tumour stroma, providing functional and structural support for tumour progression and development. The... 
tumour‐associated fibroblasts (TAFs) | cytokines | tumour stroma | pluripotency | growth factors | mesenchymal stem cells (MSCs) | Tumour stroma | Mesenchymal stem cells (MSCs) | Tumour-associated fibroblasts (TAFs) | Cytokines | Growth factors | Pluripotency | MEDICINE, RESEARCH & EXPERIMENTAL | BONE-MARROW | PROLIFERATION | INTERMEDIATE FILAMENTS | CANCER | DELIVERY | BETA | CELL BIOLOGY | tumour-associated fibroblasts (TAFs) | VEHICLES | NK CELLS | MARROW STROMAL CELLS | Tumor Necrosis Factor-alpha - metabolism | Chondrocytes - cytology | Cell Proliferation | Vimentin - metabolism | Humans | Transforming Growth Factor beta1 - metabolism | Actins - metabolism | Adipocytes - cytology | Vascular Endothelial Growth Factor A - metabolism | Fibroblasts - ultrastructure | Mesenchymal Stromal Cells - cytology | Mesenchymal Stromal Cells - ultrastructure | Hyaluronan Receptors - metabolism | Interleukin-10 - metabolism | Female | Cell Differentiation | Osteoblasts - cytology | HLA-DR Antigens - metabolism | Chondrocytes - metabolism | Fibroblasts - metabolism | Cell Line | Interleukin-1 - metabolism | Microscopy, Electron, Transmission | Bone Marrow Cells - cytology | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Fibroblasts - pathology | Muscle, Smooth - chemistry | Bone Marrow Cells - ultrastructure | Integrin beta1 - metabolism | Breast Neoplasms - pathology | Adipocytes - metabolism | Osteoblasts - metabolism | Bone Marrow Cells - metabolism | Genotype & phenotype | Stem cells | Bone marrow | Cytoskeleton | Vascular endothelial growth factor | Tumors | Index Medicus
Journal Article
by Liu, Z and Li, Q and Li, K and Chen, L and Li, W and Hou, M and Liu, T and Yang, J and Lindvall, C and Björkholm, M and Jia, J and Xu, D
Oncogene, ISSN 0950-9232, 09/2013, Volume 32, Issue 36, pp. 4203 - 4213
Telomerase activation through induction of telomerase reverse transcriptase (hTERT) contributes to malignant transformation by stabilizing telomeres. Clinical... 
hTERT | gastric cancer | EMT | CSCs | SURVIVAL | METASTASIS | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-CATENIN | TUMOR-INITIATING CELLS | CELL BIOLOGY | ONCOLOGY | GASTRIC-CANCER | GROWTH | GENETICS & HEREDITY | EXPRESSION | CARCINOMA | SNAIL | Neoplasms - metabolism | Vimentin - metabolism | Humans | Transforming Growth Factor beta1 - metabolism | Gene Expression Regulation, Neoplastic | Stomach Neoplasms - metabolism | Stomach Neoplasms - pathology | Epithelial-Mesenchymal Transition - genetics | Cell Nucleus - metabolism | Telomerase - genetics | Neoplasms - genetics | Neoplastic Stem Cells - metabolism | RNA Interference | Cell Transformation, Neoplastic - genetics | Vimentin - genetics | Hyaluronan Receptors - metabolism | Telomerase - metabolism | Transcription, Genetic | Catalysis | Snail Family Transcription Factors | Biomarkers - metabolism | Stomach Neoplasms - genetics | Promoter Regions, Genetic | Gene Expression | Signal Transduction | Neoplasm Invasiveness | Transcription Factors - genetics | Cell Transformation, Neoplastic - metabolism | beta Catenin - metabolism | Protein Transport | Transcription Factors - metabolism | Animals | Cell Line, Tumor | Protein Binding | Mice | Neoplasms - pathology | Quantitative Trait Loci | Neoplastic processes | Cellular control mechanisms | Cancer cells | Research | Properties | Observations | Telomerase | Proteins | Signal transduction | Gene expression | Stomach cancer | Stem cells | Index Medicus
Journal Article
Experimental Dermatology, ISSN 0906-6705, 2008, Volume 17, Issue 11, pp. 925 - 932
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e57020 - e57020
Lung cancer (LC) with its different subtypes is generally known as a therapy resistant cancer with the highest morbidity rate worldwide. Therapy resistance of... 
EPITHELIAL-MESENCHYMAL TRANSITION | TRANSFORMATION | THERAPY | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | GROWTH | HMGA2 | MICE | CARCINOMA | PROGRESSION | TUMOR-INITIATING CELLS | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Cadherins - metabolism | Vimentin - metabolism | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Homeodomain Proteins - metabolism | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Antigens, CD - genetics | Antigens, CD - metabolism | Octamer Transcription Factor-3 - genetics | Small Cell Lung Carcinoma - metabolism | Adenocarcinoma - metabolism | Neoplastic Stem Cells - metabolism | Vimentin - genetics | Thy-1 Antigens - genetics | Hyaluronan Receptors - metabolism | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Cadherins - genetics | Lung Neoplasms - genetics | Carcinoma, Large Cell - metabolism | Nanog Homeobox Protein | Immunophenotyping | Small Cell Lung Carcinoma - genetics | Mice, SCID | Hyaluronan Receptors - genetics | Homeodomain Proteins - genetics | Thy-1 Antigens - metabolism | Small Cell Lung Carcinoma - pathology | Animals | Octamer Transcription Factor-3 - metabolism | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Mice | Primary Cell Culture | Care and treatment | Analysis | Stem cells | Cancer cells | Physiological aspects | Research | Cancer | Adenocarcinoma | Vimentin | Cell culture | Therapy | Biotechnology | Thoracic surgery | Mesenchyme | Oct-4 protein | Lung | Lung cancer | Radiation | Population studies | Identification | Biology | mRNA | Metastasis | Cancer therapies | CD90 antigen | N-Cadherin | Immunology | CD44 antigen | Population | Medical research | Squamous cell carcinoma | Hematology | Cell division | Tumor cell lines | Gene expression | Cadherin | Spheroids | Morbidity | Medicine | Pathology | Medical prognosis | Pancreatic cancer | Cell lines | Irradiation | Prostate | Tumors | Index Medicus
Journal Article
FEBS Journal, ISSN 1742-464X, 01/2016, Volume 283, Issue 2, pp. 206 - 220
As a result of Helicobacter pylori adhesion to gastric epithelial cells, the bacterial effector cytotoxin‐associated gene A (CagA) is translocated... 
44 | CD | MMP | 1 | 3 | ZEB | matrix metalloproteinase | 9 | stromelysin‐1 | stromelysin-1/MMP-3 | ZEB1 | MMP-9 | CD44 | ACTIVATION | VIRULENCE FACTOR CAGA | BIOCHEMISTRY & MOLECULAR BIOLOGY | VACA POLYMORPHISMS | CANCER | MATRIX METALLOPROTEINASES | IN-VITRO | CARCINOGENESIS | SECRETION | EXPRESSION | MOLECULAR-MECHANISMS | Amino Acid Sequence | Gastric Mucosa - microbiology | Phosphorylation | Epithelial Cells - metabolism | Vimentin - metabolism | Humans | Bacterial Proteins - genetics | Helicobacter pylori - pathogenicity | Molecular Sequence Data | Matrix Metalloproteinase 3 - metabolism | Gastric Mucosa - metabolism | Antigens, Bacterial - genetics | Helicobacter Infections - pathology | Amino Acid Motifs | Host-Pathogen Interactions | Animals | Epithelial Cells - microbiology | Epithelial-Mesenchymal Transition | Hyaluronan Receptors - metabolism | Cell Line, Tumor | Bacterial Proteins - metabolism | Helicobacter Infections - metabolism | Antigens, Bacterial - metabolism | Helicobacter infections | Genetic aspects | Helicobacter pylori | Intermediate filament proteins | Stem cells | Proteins | Kinases | Ulcers | Index Medicus | Helicobacter Infections/pathology | Life Sciences | Vimentin/metabolism | Epithelial Cells/metabolism | Antigens, Bacterial/genetics | Antigens, Bacterial/metabolism | Biochemistry, Molecular Biology | Helicobacter pylori/pathogenicity | Hyaluronan Receptors/metabolism | Helicobacter Infections/metabolism | Bacteriology | Microbiology and Parasitology | Bacterial Proteins/metabolism | Epithelial Cells/microbiology | Bacterial Proteins/genetics | Gastric Mucosa/microbiology | Matrix Metalloproteinase 3/metabolism | Gastric Mucosa/metabolism
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2014, Volume 111, Issue 48, pp. 17104 - 17109
Metastasis portends a poor prognosis for cancer patients. Primary tumor cells disseminate through the bloodstream before the appearance of detectable... 
Vimentin | Epithelial cells | Blood cells | Cell lines | Stem cells | Fluorescence | Breast cancer | Blood | Tumors | Cancer | Diagnostic | Cancer metastasis | MRNA | Nanotechnology | NanoFlares | nanotechnology | mRNA | diagnostic | cancer metastasis | SURVIVAL | MECHANISM | MULTIDISCIPLINARY SCIENCES | PERIPHERAL-BLOOD | EPITHELIAL-MESENCHYMAL TRANSITION | REGULATOR | PREDICT | METASTATIC BREAST-CANCER | PROGRESSION | MESSENGER-RNA DETECTION | Carbocyanines - chemistry | Cadherins - metabolism | Vimentin - metabolism | Humans | Neoplastic Cells, Circulating - metabolism | Carbocyanines - metabolism | Transplantation, Heterologous | Green Fluorescent Proteins - genetics | RNA, Messenger - metabolism | DNA, Antisense - genetics | Breast Neoplasms - metabolism | Vimentin - genetics | Base Sequence | Biomarkers, Tumor - metabolism | Female | Cadherins - genetics | Gold - chemistry | Green Fluorescent Proteins - metabolism | Nanotechnology - methods | Metal Nanoparticles - chemistry | RNA, Messenger - genetics | Neoplastic Cells, Circulating - chemistry | DNA, Antisense - metabolism | Fibronectins - metabolism | Breast Neoplasms - genetics | Breast Neoplasms - blood | Cell Line, Tumor | Luminescent Proteins - genetics | Biomarkers, Tumor - genetics | Fibronectins - genetics | DNA, Antisense - chemistry | Microscopy, Fluorescence | Luminescent Proteins - metabolism | Health aspects | Identification and classification | Cancer cells | Flow cytometry | Metastasis | Ribonucleic acid--RNA | Risk assessment | Index Medicus | Biological Sciences
Journal Article
STEM CELLS, ISSN 1066-5099, 06/2013, Volume 31, Issue 6, pp. 1160 - 1169
Much controversy surrounds the identity and origin of human hepatic stem and progenitor cells in part because of a lack of small animal models in which the... 
Humanized mouse | Liver reconstitution | Hematopoietic stem/progenitor cell | Hepatic progenitor cell | Surface phenotype | Transcription profiling | CLONAL IDENTIFICATION | LIVER EPITHELIAL-CELLS | C-KIT | MESENCHYMAL STEM-CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | HUMAN HEPATOCYTES | ADULT-RAT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | MICE | HEMATOLOGY | EXPRESSION | Cell Adhesion Molecules - genetics | Antigens, CD34 - metabolism | Vimentin - metabolism | Humans | Glycoproteins - metabolism | Dendritic Cells - physiology | Monocytes - metabolism | Hepatocytes - metabolism | Stem Cells - metabolism | Liver - embryology | Antigens, CD - metabolism | Epithelial Cell Adhesion Molecule | Cell Differentiation - genetics | Lymphocytes - physiology | Peptides - metabolism | Vimentin - genetics | Antigens, Neoplasm - metabolism | Hematopoietic Stem Cells - physiology | Transcription, Genetic | Monocytes - physiology | Cell Differentiation - physiology | Dendritic Cells - metabolism | Hepatocytes - physiology | alpha-Fetoproteins - metabolism | Lymphocytes - metabolism | Antigens, Neoplasm - genetics | alpha-Fetoproteins - genetics | Albumins - metabolism | Liver - metabolism | Hematopoietic Stem Cells - metabolism | Mice, SCID | AC133 Antigen | Cell Adhesion Molecules - metabolism | Animals | Mice, Inbred NOD | Stem Cells - physiology | Liver - cytology | Mice | Albumins - genetics | Dendritic cells | T cells | Intermediate filament proteins | Analysis | Stem cells | Bone marrow | Rodents | Cells | Index Medicus
Journal Article