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Publication DateClinical Cancer Research, ISSN 1078-0432, 10/2008, Volume 14, Issue 20, pp. 6456 - 6468
xenograft | NSCLC | erlotinib | mutational analysis | anti-EGFR therapy | cetuximab | biomarker | Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the respiratory system and mediastinum | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Pneumology | Carcinoma, Large Cell - drug therapy | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Adenocarcinoma - pathology | Oligonucleotide Array Sequence Analysis | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - pathology | Humans | Lung Neoplasms - metabolism | Middle Aged | Drug Resistance, Neoplasm | Immunoblotting | Male | Gene Expression Profiling | Adenocarcinoma - metabolism | Biomarkers, Tumor - metabolism | Cetuximab | Disease Models, Animal | Genes, ras - genetics | Antibodies, Monoclonal - pharmacology | Carcinoma, Non-Small-Cell Lung - metabolism | Etoposide - pharmacology | Mutation - genetics | Adenocarcinoma - drug therapy | Small Cell Lung Carcinoma - pathology | Carcinoma, Squamous Cell - drug therapy | Mice, Nude | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Mice | Carboplatin - pharmacology | Quinazolines - pharmacology | Deoxycytidine - analogs & derivatives | Erlotinib Hydrochloride | Paclitaxel - pharmacology | Prognosis | Carcinoma, Squamous Cell - metabolism | Deoxycytidine - pharmacology | Lung Neoplasms - pathology | Small Cell Lung Carcinoma - drug therapy | Tumor Suppressor Protein p53 - genetics | Small Cell Lung Carcinoma - metabolism | Antibodies, Monoclonal, Humanized | Receptor, Epidermal Growth Factor - metabolism | Vinblastine - analogs & derivatives | Polymerase Chain Reaction | Adult | Female | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Large Cell - metabolism | Radiation-Sensitizing Agents - pharmacology | Tumor Suppressor Protein p53 - metabolism | Mice, SCID | Xenograft Model Antitumor Assays | Animals | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Aged | Protein Kinase Inhibitors - pharmacology | Vinblastine - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Antineoplastic Agents, Phytogenic - pharmacology | Index Medicus
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Loading RightsAntimicrobial agents and chemotherapy, ISSN 0066-4804, 11/2015, Volume 59, Issue 11, pp. 7011 - 7017
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Models, Theoretical | Alkaloids - pharmacology | Emetine - pharmacology | Trypanosoma brucei brucei - drug effects | Benzophenanthridines - pharmacology | Drug Synergism | Berberine - pharmacology | Animals | Piperidines - pharmacology | Trypanocidal Agents - pharmacology | Harringtonines - pharmacology | Polyunsaturated Alkamides - pharmacology | Vinblastine - pharmacology | Benzodioxoles - pharmacology | Digitonin - pharmacology | Drug Combinations | Index Medicus | Experimental Therapeutics
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Loading RightsJournal of medicinal chemistry, ISSN 0022-2623, 09/2014, Volume 57, Issue 17, pp. 7216 - 7233
Paclitaxel - pharmacology | Antioxidants - chemistry | Models, Chemical | Antineoplastic Agents - chemical synthesis | Drug Resistance, Multiple - drug effects | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Amino Acids - chemistry | Alanine - chemistry | Amino Acids - pharmacology | Dose-Response Relationship, Drug | Antineoplastic Agents - pharmacology | Molecular Structure | Alanine - pharmacology | Cell Survival - drug effects | Quercetin - chemistry | Glutamic Acid - pharmacology | Antioxidants - pharmacology | Antineoplastic Agents - chemistry | Verapamil - pharmacology | Blotting, Western | Microscopy, Confocal | Quercetin - pharmacology | Cell Line, Tumor | Vinblastine - pharmacology | Dactinomycin - pharmacology | Doxorubicin - pharmacology | Glutamic Acid - chemistry | Index Medicus
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Loading RightsOncogene, ISSN 0950-9232, 04/1999, Volume 18, Issue 13, pp. 2241 - 2251
Chemotherapy | Breast cancer | Synergy | Multiple drug effects analysis | HER-2/neu (c-erbB-2) | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes | Recombinant Proteins - therapeutic use | Doxorubicin - therapeutic use | Adenocarcinoma - pathology | Receptor, ErbB-2 - genetics | Humans | Neoplasm Proteins - immunology | Antibodies, Monoclonal - therapeutic use | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Vinblastine - therapeutic use | Topoisomerase II Inhibitors | Antimetabolites, Antineoplastic - pharmacology | Receptor, ErbB-2 - antagonists & inhibitors | Receptor, ErbB-2 - immunology | Phosphorylation - drug effects | Neoplasm Proteins - genetics | Receptor, ErbB-2 - biosynthesis | Antibodies, Monoclonal - pharmacology | Etoposide - pharmacology | Combined Modality Therapy | Adenocarcinoma - drug therapy | Breast Neoplasms - drug therapy | Antineoplastic Agents, Alkylating - therapeutic use | Drug Synergism | Antimetabolites, Antineoplastic - therapeutic use | Adenocarcinoma - therapy | Antibiotics, Antineoplastic - therapeutic use | Mice, Nude | Cyclophosphamide - pharmacology | Immunization, Passive | Fluorouracil - pharmacology | Mice | Cell Cycle - drug effects | Trastuzumab | Neoplasm Transplantation | Paclitaxel - pharmacology | Antibiotics, Antineoplastic - pharmacology | Antineoplastic Agents, Alkylating - pharmacology | Transplantation, Heterologous | Fluorouracil - antagonists & inhibitors | Cyclophosphamide - therapeutic use | Breast Neoplasms - therapy | Antibodies, Monoclonal, Humanized | Fluorouracil - therapeutic use | Protein Processing, Post-Translational - drug effects | Female | Antineoplastic Agents - pharmacology | Thiotepa - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - biosynthesis | Etoposide - therapeutic use | Treatment Outcome | Cisplatin - pharmacology | Recombinant Proteins - pharmacology | Paclitaxel - therapeutic use | Neoplasms, Hormone-Dependent - therapy | Animals | Breast Neoplasms - pathology | Neoplasms, Hormone-Dependent - pathology | Vinblastine - pharmacology | Neoplasms, Hormone-Dependent - drug therapy | Doxorubicin - pharmacology | Drug Screening Assays, Antitumor | Index Medicus
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Loading RightsCancer chemotherapy and pharmacology, ISSN 0344-5704, 5/2011, Volume 67, Issue 5, pp. 1157 - 1166
Prostate carcinoma | Medicine & Public Health | Paclitaxel | Cancer Research | Oncology | Ascorbate | Pharmacology/Toxicology | Dehydroascorbate | 5-FU | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Tumors of the urinary system | Urinary tract. Prostate gland | Gynecology. Andrology. Obstetrics | Pharmacology. Drug treatments | Nephrology. Urinary tract diseases | Biological and medical sciences | Medical sciences | Antineoplastic agents | Male genital diseases | Tumors | Cell Survival - drug effects | Taxoids - pharmacology | Apoptosis - drug effects | Humans | Male | Organoplatinum Compounds - pharmacology | Drug Synergism | Prostatic Neoplasms | Vinblastine - analogs & derivatives | Ascorbic Acid - pharmacology | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Dehydroascorbic Acid - pharmacology | Vinblastine - pharmacology | Cell Cycle - drug effects | Camptothecin - pharmacology | Camptothecin - analogs & derivatives | Epirubicin - pharmacology | Drugs | Antimitotic agents | Care and treatment | Anthracyclines | Cell cycle | Drug therapy | Organic acids | Cancer | Index Medicus | Original
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Loading RightsClinical Cancer Research, ISSN 1078-0432, 10/2005, Volume 11, Issue 20, pp. 7508 - 7515
BRCA1, BRCA2 | Xenograft models | DNA damage and repair mechanisms | Pharmacogenetics/pharmacogenomics | Gastrointestinal cancers: other | Life Sciences & Biomedicine | Oncology | Science & Technology | Chromosome fragility (bloom syndrome, ataxia telangiectasia, fanconi anemia, x-linked mental retardation...) | Chemotherapy | Pharmacology. Drug treatments | Medical genetics | Biological and medical sciences | Medical sciences | Antineoplastic agents | Paclitaxel - pharmacology | Apoptosis - drug effects | Cross-Linking Reagents - pharmacology | Humans | Deoxycytidine - pharmacology | Chlorambucil - pharmacology | Fanconi Anemia Complementation Group C Protein - genetics | Dose-Response Relationship, Drug | Pancreatic Neoplasms - drug therapy | Caspases - metabolism | Fanconi Anemia Complementation Group G Protein - genetics | Time Factors | Cross-Linking Reagents - therapeutic use | Fanconi Anemia Complementation Group G Protein - deficiency | Inhibitory Concentration 50 | Female | Antineoplastic Agents - pharmacology | Melphalan - pharmacology | Cell Survival - drug effects | Fanconi Anemia Complementation Group Proteins - deficiency | Mitomycin - therapeutic use | Pancreatic Neoplasms - pathology | Fanconi Anemia Complementation Group Proteins - genetics | Etoposide - pharmacology | Pancreatic Neoplasms - genetics | Cisplatin - pharmacology | Xenograft Model Antitumor Assays - methods | Mitomycin - pharmacology | Animals | Mice, Nude | Cell Line, Tumor | Fanconi Anemia Complementation Group C Protein - deficiency | BRCA2 Protein - deficiency | Fluorouracil - pharmacology | Mice | Vinblastine - pharmacology | Mutation | Cell Cycle - drug effects | BRCA2 Protein - genetics | Deoxycytidine - analogs & derivatives | Doxorubicin - pharmacology | Index Medicus
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Loading RightsBiochemical pharmacology, ISSN 0006-2952, 03/2008, Volume 75, Issue 6, pp. 1302 - 1312
P-glycoprotein | MRP1 | Inhibitor | Drug resistance | CBT-1 | ABCG2 | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Paclitaxel - pharmacology | Humans | Insecta | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Fluorescent Dyes - metabolism | Prazosin - metabolism | Prazosin - analogs & derivatives | Depsipeptides - pharmacology | Biological Factors - blood | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Cyclosporins - pharmacology | Quinolines - pharmacology | Alkaloids | Neoplasms - blood | Antineoplastic Agents - pharmacology | Biological Transport - drug effects | Azides - metabolism | Cell Line | Adenosine Triphosphatases - metabolism | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Verapamil - pharmacology | Neoplasms - drug therapy | Rhodamine 123 - metabolism | Animals | Biological Factors - pharmacokinetics | Cell Line, Tumor | ATP Binding Cassette Transporter, Sub-Family B | Fluorouracil - pharmacology | Vinblastine - pharmacology | Multidrug Resistance-Associated Proteins - metabolism | Biological Factors - pharmacology | Index Medicus | drug-resistance | inhibitor
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Loading RightsNature cell biology, ISSN 1465-7392, 03/2007, Volume 9, Issue 3, pp. 299 - 309
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Nonmuscle Myosin Type IIA - antagonists & inhibitors | Embryonic Stem Cells - metabolism | RNA, Small Interfering - genetics | Embryonic Stem Cells - cytology | Humans | Nocodazole - pharmacology | Cercopithecus aethiops | Cell Movement - physiology | Heterocyclic Compounds, 4 or More Rings - pharmacology | Microtubules - metabolism | Nonmuscle Myosin Type IIB - antagonists & inhibitors | Transfection | Nonmuscle Myosin Type IIA - physiology | Guanine Nucleotide Exchange Factors - metabolism | Microtubules - drug effects | Nonmuscle Myosin Type IIA - genetics | Kinesin - genetics | Aminoquinolines - pharmacology | Kinesin - antagonists & inhibitors | T-Lymphoma Invasion and Metastasis-inducing Protein 1 | Nonmuscle Myosin Type IIB - physiology | Fibroblasts - metabolism | Guanine Nucleotide Exchange Factors - genetics | Nonmuscle Myosin Type IIB - genetics | Enzyme Inhibitors - pharmacology | Pyrimidines - pharmacology | Actomyosin - metabolism | Kinesin - metabolism | Naphthalenes - pharmacology | Azepines - pharmacology | Cell Movement - drug effects | Animals | Embryonic Stem Cells - drug effects | Cell Adhesion - physiology | Fibroblasts - drug effects | rac1 GTP-Binding Protein - antagonists & inhibitors | Fibroblasts - cytology | Mice | Vinblastine - pharmacology | Thiones - pharmacology | COS Cells | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Evaluation | Motility | Microtubules | Myosin | Physiological aspects | Genetic aspects | Properties | Health aspects | Cells | Index Medicus
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Loading RightsMolecular pharmacology, ISSN 0026-895X, 09/2000, Volume 58, Issue 3, pp. 624 - 632
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Binding, Competitive | Cricetinae | Paclitaxel - pharmacology | ATP Binding Cassette Transporter, Subfamily B, Member 1 - drug effects | Allosteric Regulation | Tritium | Quinolines - pharmacology | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Rhodamine 123 - pharmacology | Animals | Benzylidene Compounds - pharmacology | Drug Interactions | Isoquinolines - pharmacology | Acridines - pharmacology | Benzimidazoles - pharmacology | Cell Membrane - metabolism | Vinblastine - pharmacology | Kinetics | Nicardipine - pharmacology | Radioligand Assay | Radiopharmaceuticals - pharmacology | Tetrahydroisoquinolines | Cell Membrane - drug effects | CHO Cells | Index Medicus
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Loading RightsMolecules (Basel, Switzerland), ISSN 1420-3049, 12/2017, Volume 22, Issue 12, p. 2152
FGFR2α | Resistance | Gastrointestinal stromal tumor cells (GISTs) | Imatinib (IM) | Receptor tyrosine kinase (RTK) inhibitors | Chemotherapeutic drugs | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Gastrointestinal Stromal Tumors - enzymology | Proto-Oncogene Proteins c-met - metabolism | Focal Adhesion Kinase 1 - genetics | Paclitaxel - pharmacology | Receptor, Fibroblast Growth Factor, Type 2 - metabolism | Epithelial Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | Proto-Oncogene Proteins c-kit - metabolism | Proto-Oncogene Proteins c-akt - genetics | Gastrointestinal Stromal Tumors - pathology | Proto-Oncogene Proteins c-kit - genetics | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Focal Adhesion Kinase 1 - metabolism | Gastrointestinal Stromal Tumors - genetics | Pyrazoles - pharmacology | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Signal Transduction | Imatinib Mesylate - pharmacology | Epithelial Cells - pathology | Pyrimidines - pharmacology | Proto-Oncogene Proteins c-met - genetics | Drug Resistance, Neoplasm - genetics | Receptor, Platelet-Derived Growth Factor alpha - genetics | Anilides - pharmacology | Epithelial Cells - enzymology | Cell Line, Tumor | Phenylurea Compounds - pharmacology | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Vinblastine - pharmacology | Doxorubicin - pharmacology | Receptor, Fibroblast Growth Factor, Type 2 - genetics | Drug Resistance, Neoplasm - drug effects | Fibroblast growth factor | Target recognition | DNA damage | Chemoresistance | Drug resistance | DNA repair | Metastases | Axl protein | c-Met protein | Proteins | Clonal deletion | Protein-tyrosine kinase receptors | Inhibition | Repair | Protein-tyrosine kinase | Growth kinetics | Deoxyribonucleic acid--DNA | Tyrosine | Imatinib | Double-strand break repair | Insulin | c-Kit protein | Amplification | Signaling | Chemotherapy | Reagents | In vivo methods and tests | Mutation | Kinetics | Focal adhesion kinase | Transporter | Tumors | Apoptosis | Fibroblast growth factor receptors | Index Medicus | gastrointestinal stromal tumor cells (GISTs) | imatinib (IM) | receptor tyrosine kinase (RTK) inhibitors | chemotherapeutic drugs | resistance
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Loading RightsCancer chemotherapy and pharmacology, ISSN 0344-5704, 2/2007, Volume 59, Issue 2, pp. 157 - 164
Biomedicine | Chemosensitivity | Oncology | Cancer Research | Confocal microscopy | Human glioblastoma cells | Pharmacology/Toxicology | Kinesin inhibitors | Monastrol analogues | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Neurology | Biological and medical sciences | Medical sciences | Tumors of the nervous system. Phacomatoses | Antineoplastic agents | Pharmacology. Drug treatments | Fluoresceins - pharmacology | Cysteine - analogs & derivatives | Flow Cytometry - methods | Paclitaxel - pharmacology | Tubulin Modulators - pharmacology | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Pyrimidines - chemistry | Dose-Response Relationship, Drug | Tubulin - metabolism | Spindle Apparatus - metabolism | Time Factors | Cysteine - pharmacology | Rotenone - pharmacology | Glioblastoma - metabolism | Molecular Structure | Kinesin - antagonists & inhibitors | Quinazolines - chemistry | Insecticides - pharmacology | Cell Survival - drug effects | Tetrahydroisoquinolines - pharmacology | Thiones - chemistry | Pyrimidines - pharmacology | Kinesin - metabolism | Acridines - pharmacology | Glioblastoma - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Spindle Apparatus - drug effects |